Can-Fite BioPharma Ltd. - CANF STOCK NEWS

Can-Fite BioPharma (NYSE American: CANF) announced plans to hold virtual investor meetings at the J.P. Morgan Healthcare Conference. The company reported a complete response to Namodenoson for hepatocellular carcinoma (HCC) in its Phase II study. In Q1 2022, patient enrollment for a pivotal Phase III trial for HCC is expected to commence, supported by the FDA and EMA’s approval of the study design. Namodenoson has Orphan Drug Designation in the U.S. and Europe, with Fast Track Status in the U.S.

These developments position Can-Fite favorably in the competitive biopharma landscape.

Can-Fite BioPharma Ltd (NYSE American: CANF) announced key upcoming events expected to enhance shareholder value throughout 2022. The company plans to release topline data from a Phase III psoriasis study in Q1 2022, examining a primary endpoint related to Piclidenoson. Additionally, it will commence enrollment in a Phase IIb NASH study and a Phase III liver cancer study in H1 2022. Can-Fite has raised $10 million recently, complementing $13.3 million reported in Q3 2021, positioning the company well for ongoing clinical trials.

Can-Fite BioPharma Ltd (NYSE American: CANF) announced plans to file new patent applications for Namodenoson, a treatment targeting advanced liver cancer. This follows clinical data where a patient with advanced hepatocellular carcinoma (HCC) exhibited complete tumor clearance after treatment. The company is set to begin patient enrollment for a pivotal Phase III trial in Q1 2022 to support a New Drug Application (NDA). Can-Fite's IP portfolio now includes approximately 200 patents across 16 families, reinforcing its position in treating advanced cancers.

Can-Fite BioPharma Ltd. (NYSE American: CANF) announced the exercise of warrants by a healthcare-focused institutional investor to purchase 150 million ordinary shares (5 million ADSs) at $2.00 each, generating gross proceeds of $10 million. The ADSs and ordinary shares are registered under a SEC Form F-1. The new warrants will allow for future purchases of up to 180 million ordinary shares at the same price. Proceeds will be used for working capital, including advancing Phase II and Phase III clinical trials for liver diseases.

Can-Fite BioPharma (NYSE American: CANF) announced that a patient in its Phase II study of Namodenoson for hepatocellular carcinoma (HCC) achieved a Complete Response, with all cancer lesions cleared. The patient has survived five years post-treatment, showcasing significant clinical benefits including normal liver function. Can-Fite plans to start a pivotal Phase III trial in Q1 2022, aiming for New Drug Application submissions. The drug has Orphan Drug Designation and Fast Track Status in the U.S. and Europe, highlighting its potential in the treatment of liver cancer.

Can-Fite BioPharma Ltd (NYSE American: CANF) announced the completion of treatment for approximately 400 psoriasis patients in its Phase III Comfort™ study. The study uses Piclidenoson, an A3 adenosine receptor agonist, with a primary endpoint of PASI 75 response at week 16. Positive interim data has been reported. The psoriasis market is projected to reach $11.3 billion by 2025. Can-Fite has out-licensed Piclidenoson in multiple regions, pending regulatory approval, with potential milestone payments and royalties.

Can-Fite BioPharma Ltd. (NYSE American: CANF) reported financial results for the quarter ended September 30, 2021, highlighting key developments in its clinical pipeline. The company completed patient enrollment in its Phase III Comfort™ psoriasis study, with results expected in Q1 2022. Notably, Can-Fite discontinued its Phase II COVID-19 trial to focus on its primary indications. The financial results show revenues of $0.65 million, a slight increase from $0.61 million, while net loss decreased to $8.49 million, down from $10.81 million in 2020. The company’s cash and equivalents reached $13.3 million, bolstered by fundraising activities.

Can-Fite BioPharma (NYSE American: CANF) announced that CEO Dr. Pnina Fishman will present at the 5th Annual NASH Summit from November 29 to December 2, 2021. Dr. Fishman's presentation, scheduled for December 1 at 1:30 PM ET, will discuss the Phase 2a study of Namodenoson, an A3AR Agonist, in treating Non-alcoholic Fatty Liver Disease and Non-alcoholic Steatohepatitis. The 5th Annual NASH Summit gathers experts to enhance understanding of NASH clinical science. Namodenoson recently completed a successful Phase IIa trial, meeting its primary endpoint.

Can-Fite BioPharma announced that its veterinary partner, Vetbiolix, has initiated a safety and efficacy study of Piclidenoson for treating canine osteoarthritis, targeting a market expected to reach $3 billion by 2024. Safety results are anticipated in Q1 2022, with efficacy data expected in Q4 2022. Piclidenoson has shown a favorable safety profile in over 1,500 human patients. The study aims to provide a safer alternative to existing treatments, with Vetbiolix responsible for development costs and potential royalties upon regulatory approval.