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Can-Fite to Present Late-Stage Clinical Pipeline and Licensing Opportunities at BIO International Convention 2026

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Can-Fite (NYSE American: CANF) will present its late-stage clinical pipeline and licensing opportunities at the BIO International Convention 2026, held June 22–25 in San Diego.

The company plans partnering meetings focused on oncology, liver disease, inflammatory disease, and regional licensing for Namodenoson and Piclidenoson.

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Positive

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Negative

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News Market Reaction – CANF

+1.00%
+1.00% Session close to close

In the Jun 17 session, CANF gained 1.00%, reflecting a mild positive market reaction.

Data tracked by StockTitan Argus on the day of publication.

Market Context

This announcement highlights Can-Fite’s intent to leverage the BIO International Convention to advan...
Analysis

This announcement highlights Can-Fite’s intent to leverage the BIO International Convention to advance licensing and commercialization discussions around its late-stage pipeline. The company features two pivotal Phase III programs, ongoing Phase II studies, and clinical experience in over 1,600 patients, alongside regional deals generating about $20M in payments. In assessing this news, investors may track future partnership announcements, progression of Namodenoson and Piclidenoson trials, and any updates related to existing licensing agreements.

Key Figures

Phase III Namodenoson: Pivotal Phase III study Phase IIa Namodenoson: Phase IIa completed Phase IIb Namodenoson: Ongoing Phase IIb study +5 more
8 metrics
Phase III Namodenoson Pivotal Phase III study Advanced hepatocellular carcinoma (HCC)
Phase IIa Namodenoson Phase IIa completed Pancreatic cancer study completed successfully
Phase IIb Namodenoson Ongoing Phase IIb study MASH indication
Phase III Piclidenoson Pivotal Phase III study Psoriasis program
Planned Phase II Phase II study planned Lowe Syndrome (rare genetic disease)
Patients treated More than 1,600 patients Clinical experience across A3AR-based programs
Licensing payments Approximately $20 million Upfront and milestone payments from regional deals
BIO Convention dates June 22–25, 2026 BIO International Convention in San Diego

Historical Context

5 past events · Latest: Jun 02 (Positive)
Pattern 5 events
Date Event Sentiment 24h Move Catalyst
Jun 02 Pancreatic data update Positive -4.0% Encouraging Namodenoson Phase 2a pancreatic cancer observations and RAS-pathway focus.
May 18 Veterinary publication Positive -3.0% Peer-reviewed Piclidenoson canine osteoarthritis data and large Vetbiolix deal potential.
May 13 Phase 2b planning Positive +7.4% Plan for Namodenoson Phase 2b combo study in pancreatic cancer after favorable Phase 2a.
Apr 30 Phase 2a results Positive +6.7% Positive Namodenoson Phase 2a pancreatic cancer data with durable disease stabilization.
Mar 30 Vetbiolix trial update Positive -4.1% Completion of enrollment in Piclidenoson canine osteoarthritis Phase 2 Vetbiolix study.

24h Move is the share-price change in the day after each event; other market factors may also have contributed.

Pattern Detected

Recent positive clinical and partnership news often produced mixed reactions, with several selloffs on good data and only some announcements aligning with upside moves.

Recent Company History

Over the last few months, CANF has repeatedly highlighted progress across Namodenoson and Piclidenoson, including positive Phase 2a pancreatic cancer data, plans for a Phase 2b combo study, and a Vetbiolix deal potentially worth up to $325 million. Despite largely positive clinical updates, share-price reactions have alternated between gains and pullbacks. Today’s BIO Convention partnering announcement continues this pattern of emphasizing an advanced pipeline and licensing strategy without adding new efficacy data.

Key Terms

phase iii, phase iia, phase iib, hepatocellular carcinoma, +3 more
7 terms
phase iii medical
"The Company's lead drug candidate, Namodenoson, is currently being evaluated in a pivotal Phase III study"
A Phase III trial is the late-stage clinical study that tests whether a medical treatment works and is safe in a large group of patients, often comparing it to standard care. Think of it as a final dress rehearsal or full-scale road test before regulators decide on approval; positive or negative results strongly influence a drug maker’s chance to sell the treatment, future revenue, and investment risk.
phase iia medical
"in pancreatic cancer following the successful completion of a Phase IIa study"
Phase IIa is an early mid-stage clinical study that tests whether a new drug or treatment shows the intended biological effect in patients and helps identify the best dose. Think of it as a focused test-drive to see if a medicine does what it’s supposed to and what dose is tolerable before larger trials. Investors watch Phase IIa results because positive findings reduce technical risk and can materially increase the program’s value, while negative results raise the likelihood of costly delays or failure.
phase iib medical
"and conducting a Phase IIb study for MASH."
Phase IIb is a mid-stage clinical trial that tests whether an experimental treatment works and what dose is best by studying it in a larger group of patients than early tests. For investors, Phase IIb results are important because they substantially reduce uncertainty about a drug’s effectiveness and safety, and positive or negative outcomes often drive company valuation, partnership interest, and the likelihood of advancing to the large, costly Phase III trials.
hepatocellular carcinoma medical
"a pivotal Phase III study for advanced hepatocellular carcinoma (HCC)"
Hepatocellular carcinoma is the most common form of primary liver cancer, arising from the main functional cells of the liver. For investors it matters because its serious health impact drives demand for diagnostic tests, treatments and long-term care; progress in trials or approvals can change a drugmaker’s revenue outlook much like a successful product launch can reshape a company’s future.
psoriasis medical
"Piclidenoson, Can-Fite's drug candidate for inflammatory diseases, is currently being evaluated in a pivotal Phase III study for psoriasis"
Psoriasis is a chronic skin condition where the body's defenses cause skin cells to build up rapidly, producing red, scaly, and often itchy patches. It matters to investors because it creates a steady market for long-term treatments, devices and services—similar to a recurring customer need—affecting drug development, clinical trial pipelines, pricing, and healthcare spending across pharmaceuticals and medical providers.
a3 adenosine receptor medical
"Can-Fite's proprietary A3 adenosine receptor (A3AR) platform technology has demonstrated a favorable safety profile"
A3 adenosine receptor is a specific protein on the surface of certain cells that acts like a lock responding to the natural molecule adenosine; when activated it influences inflammation, blood flow, and cell survival. For investors, it matters because drugs that selectively target this receptor can change disease outcomes or side-effect profiles, so clinical trial results or regulatory decisions about such drugs can materially affect biotech valuations and the potential market for new therapies.
orally administered therapies technical
"serves as the foundation for the Company's pipeline of orally administered therapies targeting cancer"
Orally administered therapies are medicines designed to be taken by mouth as tablets, capsules, liquids or chewables, delivering active drug through the digestive system. Investors care because oral drugs are usually easier and cheaper to manufacture, distribute and take than injected therapies, which can boost sales potential, patient adherence and market adoption, but they also face regulatory testing, formulation challenges and patent competition that affect profitability.

AI-generated analysis. How Rhea-AI works. Not financial advice.

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Company to Conduct Partnering Meetings Focused on Oncology, Liver Disease and Inflammatory Disease

RAMAT GAN, Israel, June 17, 2026 (GLOBE NEWSWIRE) -- Can-Fite BioPharma Ltd. (NYSE American: CANF) (TASE: CANF), a biotechnology company advancing a pipeline of proprietary small-molecule drugs targeting oncological and inflammatory diseases, today announced its participation in the BIO International Convention 2026, to be held June 22–25, 2026, in San Diego, California. BIO International Convention | June 22-25 | San Diego

During the conference, Can-Fite will conduct partnering meetings with pharmaceutical companies, biotechnology firms, and potential strategic partners to discuss licensing and commercialization opportunities for its advanced clinical-stage pipeline.

The Company's lead drug candidate, Namodenoson, is currently being evaluated in a pivotal Phase III study for advanced hepatocellular carcinoma (HCC), in pancreatic cancer following the successful completion of a Phase IIa study and conducting a Phase IIb study for MASH.  Piclidenoson, Can-Fite's drug candidate for inflammatory diseases, is currently being evaluated in a pivotal Phase III study for psoriasis and is undertaking the preparatory work for a Phase II study in the rare genetic disease, Lowe Syndrome.

Can-Fite's proprietary A3 adenosine receptor (A3AR) platform technology has demonstrated a favorable safety profile in more than 1,600 patients treated to date and serves as the foundation for the Company's pipeline of orally administered therapies targeting cancer, liver, and inflammatory diseases.

The Company has established multiple regional licensing agreements for its drug candidates and continues to pursue strategic partnerships to maximize the global value of its pipeline. To date, these agreements have generated approximately $20 million in upfront and milestone payments, with the potential for additional milestone payments and royalties.

"BIO International Convention is one of the most important partnering events in the biotechnology industry, bringing together companies seeking innovative therapeutic assets and strategic collaborations," said Dr. Sari Fishman, Vice President of Business Development at Can-Fite BioPharma. "With two pivotal Phase III programs, an ongoing Phase IIb study in MASH, and additional opportunities in oncology and rare diseases, we look forward to meeting with potential partners to discuss licensing, commercialization, and value-creating collaborations for our clinical-stage assets."

Dr. Fishman will be available for partnering meetings throughout the conference.

About Can-Fite BioPharma Ltd.

Can-Fite BioPharma Ltd. (NYSE American: CANF) (TASE: CANF) is an advanced clinical stage drug development Company with a platform technology that is designed to address multi-billion dollar markets in the treatment of cancer, liver, and inflammatory disease. The Company’s lead drug candidate, Piclidenoson recently reported topline results in a Phase 3 trial for psoriasis and commenced a pivotal Phase 3 trial. Can-Fite’s liver drug, Namodenoson, is being evaluated in a Phase III trial for hepatocellular carcinoma (HCC), a Phase 2b trial for the treatment of MASH, and in a Phase 2a study in pancreatic cancer. Namodenoson has been granted Orphan Drug Designation in the U.S. and Europe and Fast Track Designation as a second line treatment for HCC by the U.S. Food and Drug Administration. Namodenoson has also shown proof of concept to potentially treat other cancers including colon, prostate, and melanoma. CF602, the Company’s third drug candidate, has shown efficacy in the treatment of erectile dysfunction. These drugs have an excellent safety profile with experience in over 1,600 patients in clinical studies to date. For more information please visit: www.canfite.com.

Forward-Looking Statements

This press release may contain forward-looking statements, about Can-Fite’s expectations, beliefs or intentions regarding, among other things, its product development efforts. All statements in this communication, other than those relating to historical facts, are “forward looking statements”. Forward-looking statements can be identified by the use of forward-looking words such as “believe,” “expect,” “intend,” “plan,” “may,” “should” or “anticipate” or their negatives or other variations of these words or other comparable words or by the fact that these statements do not relate strictly to historical or current matters. For example, the Company is using forward-looking statements when it discusses the completion of the offerings, the satisfaction of customary closing conditions related to the offerings and the intended use of proceeds therefrom. Forward-looking statements relate to anticipated or expected events, activities, trends or results as of the date they are made. Because forward-looking statements relate to matters that have not yet occurred, these statements are inherently subject to known and unknown risks, uncertainties and other factors that may cause Can-Fite’s actual results, performance or achievements to be materially different from any future results, performance or achievements expressed or implied by the forward-looking statements. Important factors that could cause actual results, performance or achievements to differ materially from those anticipated in these forward-looking statements include, among other things, our market and other conditions, history of losses and needs for additional capital to fund our operations and our inability to obtain additional capital on acceptable terms, or at all; uncertainties of cash flows and inability to meet working capital needs; the initiation, timing, progress and results of our preclinical studies, clinical trials and other product candidate development efforts; our ability to advance our product candidates into clinical trials or to successfully complete our preclinical studies or clinical trials; our receipt of regulatory approvals for our product candidates, and the timing of other regulatory filings and approvals; the clinical development, commercialization and market acceptance of our product candidates; our ability to establish and maintain strategic partnerships and other corporate collaborations; the implementation of our business model and strategic plans for our business and product candidates; the scope of protection we are able to establish and maintain for intellectual property rights covering our product candidates and our ability to operate our business without infringing the intellectual property rights of others; competitive companies, technologies and our industry; risks related to not satisfying the continued listing requirements of NYSE American; and statements as to the impact of the political and security situation in Israel on our business. More information on these risks, uncertainties and other factors is included from time to time in the “Risk Factors” section of Can-Fite’s Annual Report on Form 20-F filed with the SEC on March 26, 2026 and other public reports filed with the SEC and in its periodic filings with the TASE. Existing and prospective investors are cautioned not to place undue reliance on these forward-looking statements, which speak only as of the date hereof. Can-Fite undertakes no obligation to publicly update or review any forward-looking statement, whether as a result of new information, future developments or otherwise, except as may be required by any applicable securities laws.

Contact

Can-Fite BioPharma
Motti Farbstein
info@canfite.com
+972-3-9241114


FAQ

What will Can-Fite (NYSE:CANF) present at BIO International Convention 2026?

Can-Fite will present its late-stage clinical pipeline and licensing opportunities at BIO International Convention 2026. According to Can-Fite, discussions will center on oncology, liver disease, and inflammatory disease programs, including Namodenoson and Piclidenoson, and potential commercialization partnerships with global pharmaceutical and biotechnology companies.

What is the clinical status of Namodenoson in Can-Fite's pipeline (CANF)?

Namodenoson is in a pivotal Phase III study for advanced hepatocellular carcinoma. According to Can-Fite, it completed a Phase IIa pancreatic cancer study and is in a Phase IIb trial for MASH, positioning Namodenoson as a key asset for partnering and regional licensing deals.

How advanced is Piclidenoson in clinical development for Can-Fite (CANF)?

Piclidenoson is being evaluated in a pivotal Phase III study for psoriasis. According to Can-Fite, the company is also preparing a Phase II study in the rare genetic disorder Lowe Syndrome, expanding Piclidenoson’s potential applications in inflammatory and rare disease markets for future partnerships.

How much licensing revenue has Can-Fite (CANF) generated from its drug candidates?

Can-Fite reports about $20 million from upfront and milestone payments under regional licensing agreements. According to Can-Fite, these deals cover its clinical-stage drug candidates and may provide additional future milestone payments and royalties, enhancing the potential long-term value of its partnered pipeline assets.

What is Can-Fite's A3 adenosine receptor platform and its safety record?

Can-Fite’s A3 adenosine receptor platform underpins its orally administered therapies for cancer, liver, and inflammatory diseases. According to Can-Fite, this platform has shown a favorable safety profile in more than 1,600 treated patients, supporting ongoing late-stage clinical programs and discussions with potential strategic partners.

Why is BIO International Convention 2026 important for Can-Fite (CANF) investors?

BIO International Convention 2026 offers Can-Fite broad access to potential licensors and strategic collaborators. According to Can-Fite, the company will hold partnering meetings to explore licensing, commercialization, and value-creating collaborations across its pivotal Phase III programs and other advanced clinical-stage assets.