Welcome to our dedicated page for Candel Therapeutics news (Ticker: CADL), a resource for investors and traders seeking the latest updates and insights on Candel Therapeutics stock.
Candel Therapeutics, Inc. (CADL) is a Massachusetts-based biotechnology company, also known as Advantagene, Inc., specializing in the development of cutting-edge immuno-oncology platforms aimed at treating solid tumors. The company's focus is on leveraging the body's immune system to combat cancer through innovative viral immunotherapies.
At the core of Candel Therapeutics' technology are two proprietary platforms: the Gene Mediated Cytotoxic Immunotherapy (GMCI™) platform and the RQNestin34.5 platform. Designed as an 'off-the-shelf' solution, GMCI™ aims to generate a personalized and precise immune response against cancer, utilizing the patient's own immune system. The RQNestin34.5 platform, on the other hand, is centered around the use of genetically modified herpes simplex virus (HSV) constructs to target and destroy cancer cells.
As a clinical-stage biopharmaceutical company, Candel Therapeutics is dedicated to translating its scientific advancements into viable treatments for patients. The company has made substantial progress with its platforms, demonstrating promising results in clinical studies aiming to establish the efficacy and safety of these novel therapies.
Among the company's recent highlights is its presentation at the American Society of Clinical Oncology (ASCO), where it shared significant updates on its ongoing projects. Candel Therapeutics continues to engage in strategic partnerships and collaborations to advance its mission of making effective cancer treatments accessible to patients globally.
Candel Therapeutics is committed to maintaining robust investor relations, offering transparent updates and clear communication about its financial health, project milestones, and future directions. The company's leadership frequently engages with stakeholders to ensure alignment with their goals and expectations.
For the latest news and detailed financial information, investors and interested parties can contact Theodore Jenkins, Vice President of Investor Relations and Business Development, at tjenkins@candeltx.com or Kyle Evans, Account Director at ICR Westwicke, at CandelPR@westwicke.com.
Candel Therapeutics, Inc. (Nasdaq: CADL) reported financial results for Q4 and FY 2022, showcasing promising advancements in its viral immunotherapy programs. The company extended its cash runway into Q2 2024 with cash and equivalents of $70.1 million, down from $82.6 million in 2021. Notably, CAN-2409 demonstrated a 77% disease control rate in non-small cell lung cancer patients. Candel anticipates multiple clinical data readouts in 2023, including topline results from its prostate cancer trial in Q4 2024. Despite a net loss of $5.1 million for Q4 2022, the company's strategic partnerships and ongoing trials bolster its potential to innovate cancer treatments.
Candel Therapeutics (Nasdaq: CADL) announced that CEO Paul Peter Tak will participate in a fireside chat at the Guggenheim 2023 Healthcare Talks Oncology Day on February 8, 2023, at 3:20 p.m. EST. This event will occur at the St. Regis Hotel in New York City. A live webcast can be accessed under the 'Events and Presentations' section on Candel's website, with a replay available for 30 days after the event.
Candel is focused on developing novel viral immunotherapies to treat cancer, utilizing genetically modified adenovirus and herpes simplex virus platforms. Their lead candidates are CAN-2409 and CAN-3110.
Candel Therapeutics, a clinical stage biopharmaceutical company focused on viral immunotherapies, announced that CEO Paul Peter Tak will participate in a virtual fireside chat at B. Riley Securities’ 3rd Annual Oncology Conference. The event is scheduled for January 19, 2023, at 11:30 am EST. A live webcast will be available on the company’s website, with an archive accessible for 90 days post-event. Candel is known for its innovative approaches to cancer treatment, employing genetically modified viruses to enhance anti-tumor immune responses.
Candel Therapeutics (Nasdaq: CADL) presented promising data from its oncology pipeline, highlighting CAN-2409's 77% disease control rate in advanced non-small cell lung cancer patients and CAN-3110's median overall survival of 11.6 months in recurrent high-grade glioma. The company plans to prioritize CAN-3110 for further development and will not pursue phase 3 trials for CAN-2409 in glioma. Additionally, Candel announced a partnership with the University of Pennsylvania to enhance CAR-T cell therapies using its enLIGHTEN™ Discovery Platform. Cash reserves were reported at $77.2M, ensuring operations into Q1 2024.
Candel Therapeutics (Nasdaq: CADL) will host its first virtual R&D Day on December 6, 2022, presenting new clinical data from its phase 2 trial of CAN-2409 in late-stage non-small cell lung cancer (NSCLC) and CAN-3110 in high-grade glioma. The event will showcase insights from leading experts in immunology and oncology, discussing therapeutic combination opportunities and the scientific rationale behind Candel's collaboration with the University of Pennsylvania using the enLIGHTEN™ discovery platform. An interactive Q&A session will follow the presentations.
Candel Therapeutics presented updated results from its phase 1 trial of CAN-3110 for recurrent high-grade glioma (rHGG) at the SNO Annual Meeting. The trial involved 41 patients, with no dose-limiting toxicities observed. The median overall survival was reported at 11.6 months post-administration, with one patient achieving a complete response lasting over a year. The treatment showed positive effects on T cell activation and diversity, suggesting a shift in the tumor microenvironment. Future studies will explore the impact of multiple CAN-3110 injections on survival.
Candel Therapeutics, Inc. (Nasdaq: CADL) presented late-breaking data from a phase 1 trial of its lead viral immunotherapy, CAN-2409, combined with nivolumab for high-grade glioma patients. The combination showed promising results, being well tolerated with no significant added toxicity. It induced systemic immune activation and improved median overall survival (mOS) for patients with methylated MGMT promoter to 30.6 months after gross total resection. The trial supports the potential therapeutic synergy between CAN-2409 and immune checkpoint inhibitors.
Candel Therapeutics (Nasdaq: CADL) reported Q3 2022 results, achieving significant developments, including a partnership with the University of Pennsylvania's Center for Cellular Immunotherapies to explore viral immunotherapy and CAR-T cell combinations. The Company secured orphan drug designation for CAN-2409 in glioma and added new leadership. Financially, Q3 net loss decreased to $8.7 million from $16.2 million YoY. Cash position stood at $77.2 million, sufficient to sustain operations through Q1 2024.
Candel Therapeutics (Nasdaq: CADL) announced new clinical data to be presented at the 37th Annual Meeting of the Society for Immunotherapy of Cancer and the 27th Annual Meeting of the Society for Neuro-Oncology, scheduled for November 11 and 18, 2022, respectively. Key highlights include presentations on CAN-2409's efficacy in high-grade glioma and its impact on tumor microenvironments. These findings could significantly advance understanding of viral immunotherapy in treating cancer.
On November 1, 2022, Candel Therapeutics, Inc. (Nasdaq: CADL) announced that its CEO, Paul Peter Tak, will participate in several investor conferences this month. The events include the Credit Suisse 31st Annual Healthcare Conference on November 8 at 8:35 am PT, the BMO Biopharma Spotlight Series: Oncology Day on November 9 at 10:00 am ET, and the Jefferies London Healthcare Conference on November 16 at 7:25 am GMT. For webcast recordings, visit Candel's website. Candel focuses on developing viral immunotherapies for cancer using genetically modified viruses to enhance anti-tumor responses.
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