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Candel Therapeutics, Inc. - CADL STOCK NEWS

Welcome to our dedicated page for Candel Therapeutics news (Ticker: CADL), a resource for investors and traders seeking the latest updates and insights on Candel Therapeutics stock.

Candel Therapeutics, Inc. (CADL) is a Massachusetts-based biotechnology company, also known as Advantagene, Inc., specializing in the development of cutting-edge immuno-oncology platforms aimed at treating solid tumors. The company's focus is on leveraging the body's immune system to combat cancer through innovative viral immunotherapies.

At the core of Candel Therapeutics' technology are two proprietary platforms: the Gene Mediated Cytotoxic Immunotherapy (GMCI™) platform and the RQNestin34.5 platform. Designed as an 'off-the-shelf' solution, GMCI™ aims to generate a personalized and precise immune response against cancer, utilizing the patient's own immune system. The RQNestin34.5 platform, on the other hand, is centered around the use of genetically modified herpes simplex virus (HSV) constructs to target and destroy cancer cells.

As a clinical-stage biopharmaceutical company, Candel Therapeutics is dedicated to translating its scientific advancements into viable treatments for patients. The company has made substantial progress with its platforms, demonstrating promising results in clinical studies aiming to establish the efficacy and safety of these novel therapies.

Among the company's recent highlights is its presentation at the American Society of Clinical Oncology (ASCO), where it shared significant updates on its ongoing projects. Candel Therapeutics continues to engage in strategic partnerships and collaborations to advance its mission of making effective cancer treatments accessible to patients globally.

Candel Therapeutics is committed to maintaining robust investor relations, offering transparent updates and clear communication about its financial health, project milestones, and future directions. The company's leadership frequently engages with stakeholders to ensure alignment with their goals and expectations.

For the latest news and detailed financial information, investors and interested parties can contact Theodore Jenkins, Vice President of Investor Relations and Business Development, at tjenkins@candeltx.com or Kyle Evans, Account Director at ICR Westwicke, at CandelPR@westwicke.com.

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Candel Therapeutics, Inc. (CADL) receives FDA Fast Track Designation for CAN-3110, a promising oncolytic viral immunotherapy candidate for recurrent high-grade glioma. Positive results from the phase 1b clinical trial show a nearly doubled median overall survival with a single injection, highlighting the therapy's potential to address the unmet needs in this therapy-resistant condition.
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Candel Therapeutics, Inc. (Nasdaq: CADL) has highlighted upcoming milestones, including data readouts in lung, pancreatic, brain, and prostate cancer, as well as recent successes in immunotherapy. The company received Fast Track Designation from the FDA for its product candidate, CAN-2409, and reported positive clinical trial data for CAN-3110. These developments position Candel for progress and differentiation in the cancer therapeutics market.
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Candel Therapeutics, Inc. (Candel) (Nasdaq: CADL) has been granted Fast Track Designation by the FDA for its lead investigational adenovirus asset CAN-2409 plus prodrug for the treatment of pancreatic ductal adenocarcinoma (PDAC) to improve overall survival. The company presented encouraging overall survival and immunological biomarker data based on an interim analysis of the randomized, phase 2 clinical trial at the Society for Immunotherapy of Cancer (SITC) Annual Meeting. The estimated survival rate of patients who received the CAN-2409 plus prodrug regimen was 71.4% at both 24 and 36 months, compared to only 16.7% in patients treated with standard of care (SoC) chemoradiation prior to surgery alone. Candel remains on track to release updated overall survival data in the second quarter of 2024.
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Candel Therapeutics, Inc. (CADL) strategically restructures to focus on developing CAN-3110 and the enLIGHTEN™ Discovery Platform, reducing workforce by 50% to extend cash runway into Q4 2024. The company aims to prioritize spend on clinical data readouts for CAN-2409 in non-small cell lung cancer, pancreatic cancer, and prostate cancer in 2024.
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Candel Therapeutics, Inc. (CADL) reported positive survival data from phase 2 trials of CAN-2409 in NSCLC and pancreatic cancer, and CAN-3110 in recurrent HGG. The company also presented promising results for Alpha-201-macro1 and provided a corporate update on financial results.
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Candel Therapeutics presents two posters at the 2023 SITC Annual Meeting, showcasing the enLIGHTEN™ Discovery Platform. The platform combines artificial intelligence, machine learning, and herpes simplex virus to develop viral immunotherapies for solid tumors. The first poster highlights the potential of the enLIGHTEN™ viral chassis Alpha-201 to orchestrate changes in the tumor microenvironment and enhance anti-tumor immune responses. The second poster introduces Alpha-201-macro1, an investigational agent designed to interfere with the CD47/SIRPα pathway and demonstrate potent anti-tumor effects.
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Candel Therapeutics announced positive interim data from a phase 2 clinical trial of CAN-2409 for pancreatic cancer. The overall survival rate at 36 months was 71.4% in CAN-2409 treated patients compared to 16.7% in the control arm. Immune response was observed in PDAC tissue after CAN-2409 treatment. The treatment was well tolerated with no dose-limiting toxicities.
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Candel Therapeutics announces positive results from the first-in-human clinical trial of CAN-3110 in recurrent high-grade glioma
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Candel Therapeutics to present three posters at SITC Annual Meeting, including clinical trial data for CAN-2409 in pancreatic cancer
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Candel Therapeutics announces updated activity data from its phase 2 clinical trial of CAN-2409 in non-small cell lung cancer patients. The data shows an encouraging number of long survivors, with 10 patients living over 18 months and 4 patients living over 24 months. These patients had low or negative PD-L1 expression, suggesting CAN-2409's potential to convert immunosuppressive tumors into long-term survivors. Biomarker data also indicates a correlation between immune cell activation and survival. Overall survival data for Cohort 2 is expected in Q2 2024.
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FAQ

What is the current stock price of Candel Therapeutics (CADL)?

The current stock price of Candel Therapeutics (CADL) is $5.09 as of November 7, 2024.

What is the market cap of Candel Therapeutics (CADL)?

The market cap of Candel Therapeutics (CADL) is approximately 163.3M.

What does Candel Therapeutics, Inc. specialize in?

Candel Therapeutics focuses on developing immuno-oncology platforms aimed at treating solid tumors using viral immunotherapies.

What are the main platforms developed by Candel Therapeutics?

The main platforms are the Gene Mediated Cytotoxic Immunotherapy (GMCI™) platform and the RQNestin34.5 platform.

How does the GMCI™ platform work?

The GMCI™ platform generates a personalized immune response against cancer using the patient's own immune system.

What is unique about the RQNestin34.5 platform?

The RQNestin34.5 platform uses genetically modified herpes simplex virus (HSV) constructs to target and destroy cancer cells.

Is Candel Therapeutics a clinical-stage company?

Yes, Candel Therapeutics is a clinical-stage biopharmaceutical company focused on viral immunotherapies for cancer treatment.

What recent achievements has Candel Therapeutics made?

Candel Therapeutics presented significant updates at the American Society of Clinical Oncology (ASCO) and continues to progress in its clinical studies.

Who can I contact for investor relations at Candel Therapeutics?

You can contact Theodore Jenkins, Vice President of Investor Relations and Business Development, at tjenkins@candeltx.com.

Who handles media inquiries for Candel Therapeutics?

Media inquiries are handled by Kyle Evans, Account Director at ICR Westwicke, reachable at CandelPR@westwicke.com.

What types of cancer are targeted by Candel Therapeutics' platforms?

Candel Therapeutics focuses on treating solid tumors through its immuno-oncology platforms.

Where is Candel Therapeutics based?

Candel Therapeutics is based in Massachusetts, USA.

Candel Therapeutics, Inc.

Nasdaq:CADL

CADL Rankings

CADL Stock Data

163.31M
32.09M
30.85%
20.36%
5.11%
Biotechnology
Biological Products, (no Disgnostic Substances)
Link
United States of America
NEEDHAM