BioXcel Therapeutics to Present an Update from its Ongoing Trial of BXCL701 in Aggressive Forms of Prostate Cancer at the 2021 ASCO Genitourinary Cancers Symposium

Rhea-AI Summary

BioXcel Therapeutics (BTAI) has announced an update regarding its Phase 1b/2 trial of BXCL701, an investigational oral innate immunity activator for aggressive prostate cancer. The update will be presented at the virtual 2021 ASCO Genitourinary Cancers Symposium from February 11 to 13, 2021. The poster, titled BXCL701 combined with pembrolizumab in men with metastatic castration-resistant prostate cancer, will be available starting February 11 at 8:00 a.m. ET. BXCL701 aims to convert 'cold' tumors into 'hot' tumors, enhancing immune response against cancer.

NEW HAVEN, Conn., Feb. 04, 2021 (GLOBE NEWSWIRE) -- BioXcel Therapeutics, Inc. ("BioXcel" or the "Company") (Nasdaq: BTAI), a clinical-stage biopharmaceutical company utilizing artificial intelligence approaches to develop transformative medicines in neuroscience and immuno-oncology, today announced that an update from its ongoing Phase 1b/2 trial of BXCL701, the Company's investigational, oral innate immunity activator, in aggressive forms of prostate cancer will be presented in a poster session at the virtual 2021 ASCO Genitourinary ("ASCO GU") Cancers Symposium. ASCO GU is being held from Thursday, February 11, 2021 to Saturday, February 13, 2021.

Poster Presentation Details:
Title: BXCL701, first-in-class oral activator of systemic innate immunity pathway, combined with pembrolizumab (Keytruda) in men with metastatic castration-resistant prostate cancer (mCRPC)
Poster Session: Prostate Cancer - Advanced
Time: Available starting on February 11, 2021 at 8:00 a.m. Eastern Time
Abstract Number: 124

The abstract will be available on the ASCO GU website at meetinglibrary.asco.org/ on Monday, February 8, 2021 at 5:00 p.m. ET. At the start of the poster session, the poster will be available in the “News & Media” section of the Company’s website at www.bioxceltherapeutics.com.

About BXCL701

BXCL701 is an investigational orally administered innate immune activator designed to initiate inflammation in the tumor microenvironment. Approved and experimental immunotherapies often struggle to address cancers that appear "cold" or uninflamed. Therefore, BXCL701 may render "cold" tumors "hot," making them more detectable by the adaptive immune system and thereby facilitating the development of a strong anti-cancer immune response. BTI's preclinical data supports BXCL701's synergy with both current checkpoint inhibitor-based therapies and emerging immunotherapies directed to activate T-cells, such as IL-2.

This candidate is currently being developed as therapy for aggressive forms of prostate cancer ("cold" tumor) and advanced solid tumors that are refractory or treatment naïve to checkpoint inhibitors ("hot" tumors).

BioXcel Therapeutics, Inc.

BioXcel Therapeutics, Inc. is a clinical stage biopharmaceutical company focused on drug development that utilizes artificial intelligence approaches to develop transformative medicines in neuroscience and immuno-oncology. BioXcel's drug re-innovation approach leverages existing approved drugs and/or clinically validated product candidates together with big data and proprietary machine learning algorithms to identify new therapeutic indices. BioXcel's two most advanced clinical development programs are BXCL501, an investigational, proprietary, orally dissolving thin film formulation of dexmedetomidine for the treatment of agitation and opioid withdrawal symptoms, and BXCL701, an investigational, orally administered, systemic innate immunity activator in development for the treatment of aggressive forms of prostate cancer and advanced solid tumors that are refractory or treatment naïve to checkpoint inhibitors. For more information, please visit www.bioxceltherapeutics.com.

Contact Information:

BioXcel Therapeutics, Inc.

www.bioxceltherapeutics.com

Investor Relations:

Mary Coleman
BioXcel Therapeutics, VP of Investment Relations
MColeman@bioxceltherapeutics.com
1.475.238.6837

John Graziano
Solebury Trout
jgraziano@soleburytrout.com
1.646.378.2942

Media:

Julia Deutsch
Solebury Trout
jdeutsch@soleburytrout.com
1.646.378.2967

 

FAQ

What is the purpose of the BXCL701 trial announced by BioXcel Therapeutics (BTAI)?

The BXCL701 trial aims to evaluate its effectiveness as an oral innate immunity activator in treating aggressive forms of prostate cancer.

When will the BXCL701 trial update be presented at the ASCO GU Symposium?

The update on BXCL701 will be presented from February 11 to 13, 2021, at the virtual ASCO Genitourinary Cancers Symposium.

What is the significance of BXCL701 in treating 'cold' tumors?

BXCL701 is designed to activate the innate immune system, potentially converting 'cold' tumors into 'hot' tumors to improve detection and treatment.

What is the poster title for the BXCL701 presentation at ASCO GU?

The poster is titled BXCL701, first-in-class oral activator of systemic innate immunity pathway, combined with pembrolizumab in men with metastatic castration-resistant prostate cancer.

Where can I find the BXCL701 abstract for the ASCO GU Symposium?

The abstract will be available on the ASCO GU website starting February 8, 2021, at 5:00 p.m. ET.