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Benitec Biopharma Inc. (NASDAQ: BNTC) is a clinical-stage biotechnology company pioneering the use of its proprietary 'Silence and Replace' DNA-directed RNA interference (ddRNAi) platform to develop novel genetic medicines. Headquartered in Hayward, California, Benitec is focused on creating treatments for chronic and life-threatening human diseases through gene-silencing technology that targets and 'turns off' specific disease-related genes, offering sustained treatments, and even potential cures, with a single dose.
Benitec's ddRNAi technology combines RNA interference with gene therapy to deliver long-lasting silencing of disease-causing genes. This approach has significant advantages over traditional RNA interference methods, being easier to deliver, safer, more targeted, and more efficient. This transformative technology is protected by over 40 global patents and can potentially silence genes related to thousands of human diseases.
The company is advancing a robust pipeline of in-house and partnered drug development programs targeting conditions such as Oculopharyngeal Muscular Dystrophy (OPMD) and Hepatitis B Virus (HBV). One of its leading projects, BB-301, is designed to slow or halt the progression of OPMD by silencing the faulty mutant PABPN1 gene and replacing it with a functional version. The BB-301 program has shown promising preliminary results, with significant improvements in clinical trial endpoints.
Benitec has recently announced several operational updates, including the initiation of the first clinical trial using the 'Silence and Replace' platform and the successful closing of a $40 million PIPE financing to support the development and commercialization of BB-301. The company's financial condition shows a focused investment in research and development with notable participation from prominent investors.
For the latest updates on Benitec Biopharma's performance, projects, and developments, visit their official website at www.benitec.com.
Benitec Biopharma (NASDAQ: BNTC) reported its financial results for the second fiscal quarter ending December 31, 2022. Revenue decreased to $14,000 from $25,000 year-over-year, while operating expenses rose to $5.6 million. Research and development expenses specifically for its OPMD project increased to $3.8 million. Notably, the first patient has been enrolled in the BB-301 clinical development program aimed at treating Oculopharyngeal Muscular Dystrophy (OPMD). The company anticipates interim clinical results in 2023 following a six-month observational study and subsequent dosing of BB-301.
Benitec Biopharma Inc. (NASDAQ: BNTC) has announced the enrollment of its first patient into the natural history phase of its BB-301 clinical development program targeted at oculopharyngeal muscular dystrophy (OPMD). This six-month pre-treatment observation phase aims to evaluate baseline patient conditions before proceeding with the Phase 1b/2a treatment study scheduled for 2023. CEO Jerel A. Banks stated that high enrollment interest has been reported, marking a significant milestone for the Company's clinical development goals. The NH Study will utilize various quantitative radiographic measures to assess dysphagia progression in OPMD patients.
Benitec Biopharma Inc. (NASDAQ: BNTC) announced its Fiscal Year First Quarter financial results for the period ending September 30, 2022. The company reported a net loss of $5.1 million, or $0.47 per share, an improvement from a net loss of $5.0 million, or $0.62 per share, in the same quarter last year. Total revenues remained at $0. Total expenses decreased to $4.6 million from $4.8 million. Significant progress was made in the Oculopharyngeal Muscular Dystrophy (OPMD) Natural History Study, with subject screening set to start in November 2022. The company anticipates initiating its BB-301 treatment study in 2023.
Benitec Biopharma Inc. (Nasdaq: BNTC) has successfully closed a public offering of 29,809,471 shares of common stock at a price of $0.60 each, along with warrants to purchase an equal number of shares. The offering generated approximately $17.9 million prior to expenses. The proceeds will be used for the clinical development of BB-301, including various studies, and to advance other product candidates, as well as for general corporate purposes. JMP Securities acted as the sole book-running manager for this offering.
Benitec Biopharma (BNTC) has priced an underwritten public offering of 29,809,471 shares of its common stock, including pre-funded warrants, and accompanying warrants at a combined price of $0.60 per share. The offering aims to raise approximately $17.9 million for clinical development of its product BB-301 and related growth activities, with expected closure on September 15, 2022. The warrants are exercisable upon increase in authorized shares, with an exercise price of $0.66, expiring five years from the initial exercise date.
Benitec Biopharma (NASDAQ: BNTC) reported financial results for FY 2022, ending June 30, 2022. Total revenues increased to $73,000, up from $59,000 in FY 2021, primarily due to higher licensing and royalty revenues. However, total expenses rose to $17.9 million, leading to a net loss of $18.2 million or $2.23 per share, compared to a net loss of $13.9 million or $3.23 per share the previous year. The company is advancing its gene therapy pipeline, particularly the BB-301 program for Oculopharyngeal Muscular Dystrophy, with clinical trials planned to start in 2023.
Benitec Biopharma Inc. (BNTC) reported its Q3 Fiscal Year 2022 financial results, showing total revenues of $48,000, a significant increase from $1,000 in Q3 2021. The company's operating expenses decreased to $3.5 million, down from $3.79 million in the previous year. Benitec is advancing its BB-301 clinical development program, with key milestones achieved, including the completion of necessary regulatory submissions in France. The first patients are expected to enroll in the BB-301 treatment study by April 2023, following a six-month observational period.
Benitec Biopharma (NASDAQ: BNTC) reported its Q2 financial results for FY 2022. Total revenues increased to $25,000 from $1,000 in Q2 2021, attributed to licensing and royalty income. Operating expenses rose to $4.9 million, up from $3.2 million, primarily driven by higher research and development costs. The net loss for the quarter was $4.8 million, or $0.59 per share. Key developments include successful regulatory interactions supporting the BB-301 clinical program, expected to commence in mid-2022, targeting Oculopharyngeal Muscular Dystrophy.
Benitec Biopharma (BNTC) reported its Q1 fiscal results for the period ending September 30, 2021. The company reported total revenues of $0, down from $55,000 in Q1 2020, primarily due to reduced licensing and royalty revenues. Operating expenses surged to $4.8 million, compared to $2.7 million in the prior year, with research and development costs rising significantly to $2.8 million. The net loss reached $5 million, highlighting a negative EPS of $0.62. Positive updates were shared regarding the BB-301 program, including successful animal studies and planned Phase 1b/2a trials set for 2022.
Benitec Biopharma (NASDAQ: BNTC) provided an operational update and announced its fiscal year 2021 results, ending June 30. Total revenue was $59,000, a decrease from $102,000 in 2020, largely due to the cessation of government grants. Total expenses grew to $13.7 million from $8.4 million the previous year, with significant increases in R&D costs. The net loss was $13.9 million, or $3.23 per share, compared to a loss of $8.3 million, or $8.10 per share in 2020. The firm has $19.8 million in cash as it progresses its gene therapy programs, particularly BB-301 for Oculopharyngeal Muscular Dystrophy.