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Anavex Life Sciences Corp. (Nasdaq: AVXL) is a clinical-stage biopharmaceutical company dedicated to the development of novel therapeutics for neurodegenerative and neurodevelopmental disorders. Headquartered in New York, Anavex focuses on precision medicine to treat diseases with high unmet medical needs, such as Alzheimer's disease, Parkinson's disease, Rett syndrome, and schizophrenia.
Anavex's lead compound, ANAVEX 2-73 (blarcamesine), is an orally available small molecule targeting sigma-1 and muscarinic receptors. It aims to restore cellular homeostasis, showing promise in multiple CNS disorders. Blarcamesine has successfully completed Phase 2a and Phase 2b/3 trials for Alzheimer's disease and various studies in Rett syndrome, including a recent Phase 2/3 EXCELLENCE pediatric trial demonstrating significant improvements in Rett Syndrome Behaviour Questionnaire (RSBQ) scores.
The company also has other promising drug candidates, such as ANAVEX 3-71, targeting sigma-1 and M1 muscarinic receptors. This candidate has exhibited disease-modifying activity in Alzheimer's disease models and is currently in a Phase 2 trial for schizophrenia.
Anavex actively engages in partnerships and collaborations, including support from the Michael J. Fox Foundation for Parkinson's Research. With a robust intellectual property portfolio, Anavex is committed to advancing its pipeline through rigorous clinical trials to bring effective treatments to market.
Recent highlights include presenting at key industry conferences and filing a Marketing Authorisation application with the European Medicines Agency (EMA) for blarcamesine in Alzheimer's disease. Anavex also recently bolstered its executive team with seasoned professionals to drive its R&D and clinical strategies forward.
For more information, visit www.anavex.com or follow the company on Twitter, Facebook, Instagram, and LinkedIn.
Anavex Life Sciences Corp. (Nasdaq: AVXL) announced that its CEO, Christopher U. Missling, PhD, will participate in a panel discussion titled “Establishing Mutually Beneficial Collaborations” at the World EPA Congress 2021 on April 15, 2021. Anavex is focused on developing therapies for neurodegenerative disorders like Alzheimer's and Parkinson’s diseases. Their lead candidate, ANAVEX®2-73, has shown promising results in Phase 2 trials targeting Alzheimer’s and Parkinson’s dementia. The World EPA Congress is a key event in healthcare evidence and pricing, happening from April 13-15, 2021.
Anavex Life Sciences Corp. (Nasdaq: AVXL) announced that the Independent Data Safety Monitoring Board (DSMB) has reviewed the preliminary data from its Phase 2b/3 Alzheimer’s study of ANAVEX®2-73 (blarcamesine). The DSMB recommended continuing the study without modifications. The ongoing clinical trial is over 92% enrolled, focusing on safety and efficacy, with endpoints assessing cognition and daily function. ANAVEX®2-73 targets the sigma-1 receptor and may restore neural homeostasis, signaling potential in neurodegenerative treatments.
Anavex Life Sciences Corp. (AVXL) announced the inclusion of ANAVEX®2-73 (blarcamesine) in a peer-reviewed article published in Neuropharmacology. This publication highlights the drug's potential in treating Alzheimer's disease based on a 57-week Phase 2a trial with 32 patients, showing significant improvements in cognition and daily activities, particularly in those with a functional SIGMAR1 gene. A follow-up study demonstrated further efficacy. An ongoing Phase 2b/3 trial is set to refine patient selection using these findings.
Anavex Life Sciences Corp. (Nasdaq: AVXL) announced that Christopher U. Missling, PhD, President and CEO, will present at the H.C. Wainwright Global Life Sciences Conference on March 9-10, 2021. The presentation will be available as a webcast on Anavex's website starting March 9, 2021. The company is focused on developing therapeutics for neurodegenerative disorders like Alzheimer’s and Parkinson’s diseases. Anavex’s lead drug candidate, ANAVEX®2-73, has shown promising results in clinical trials for Alzheimer's and Parkinson’s diseases, targeting key receptors to restore cellular homeostasis.
Anavex Life Sciences Corp. (Nasdaq: AVXL) announced that its CEO, Christopher U. Missling, PhD, will participate in the NIH virtual Rare Disease Day® event on March 1, 2021. The event aims to raise awareness about rare diseases and facilitate discussions among stakeholders in research and therapeutic development. Anavex is committed to advancing therapeutics for neurodegenerative disorders like Alzheimer’s and Parkinson’s. This event is free and open to the public, showcasing discussions, stories, and collaborations in the field.
Anavex Life Sciences Corp. (Nasdaq: AVXL), a clinical-stage biopharmaceutical company, announced that CEO Christopher U. Missling will present at the Precision in Clinical Trials Virtual Summit on February 24, 2021. The company focuses on therapeutics for neurodegenerative disorders, with lead candidate ANAVEX®2-73 having successfully completed Phase 2a trials for Alzheimer's and Parkinson's diseases. The candidate targets sigma-1 and muscarinic receptors and has shown potential in halting disease progression according to preclinical studies.
Anavex Life Sciences Corp. (Nasdaq: AVXL) announced its participation in the 10th Annual SVB Leerink Global Healthcare Conference. Christopher U. Missling, PhD, President and CEO, will present on February 25th, 2021, at 12:00 p.m. EST, discussing the company's progress on therapeutics for neurodegenerative disorders like Alzheimer’s and Parkinson’s. The presentation will be available via webcast and can be replayed online. Anavex is known for its lead drug candidate, ANAVEX®2-73, which recently completed successful clinical trials.
Anavex Life Sciences Corp. (Nasdaq: AVXL) reported its financial results for the fiscal quarter ended December 31, 2020, posting a net loss of $7.9 million, or $0.12 per share. As of the reporting date, the company had approximately $75 million in cash and cash equivalents, providing a runway for up to three years. ANAVEX®2-73 is advancing in clinical trials for Alzheimer’s, Parkinson’s, and Rett syndrome, with 86% recruitment in the ongoing Phase 2b/3 Alzheimer's trial. Recent milestones include a $995,862 research grant from the Michael J. Fox Foundation.
Anavex Life Sciences Corp. (Nasdaq: AVXL) will release its financial results for the fiscal quarter ending December 31, 2020, on February 11, 2021. A conference call will be held at 4:30 pm ET to discuss these results, along with updates on clinical programs and corporate highlights. Anavex is focused on developing therapies for neurodegenerative disorders like Alzheimer’s and Parkinson’s diseases. The company’s lead candidate, ANAVEX®2-73, has shown promise in clinical trials targeting significant CNS diseases.
Anavex Life Sciences Corp. (Nasdaq: AVXL) has received a research grant of $995,862.51 from The Michael J. Fox Foundation for Parkinson’s Research to further develop ANAVEX®2-73 (blarcamesine) as a treatment for Parkinson’s disease. This funding follows a previous award that supported preclinical studies indicating the drug’s potential as a disease-modifying treatment. ANAVEX®2-73 targets the sigma-1 receptor, crucial for promoting neuroplasticity and restoring neural cell homeostasis. Parkinson's disease affects over 10 million people globally, underlining the significance of this research.
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