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Atara Biotherape - ATRA STOCK NEWS

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Overview of Atara Biotherapeutapeutics Inc

Atara Biotherapeutics Inc (Symbol: ATRA) is a U.S.-based biotherapeutics company dedicated to developing innovative therapies aimed at transforming the treatment landscape for patients suffering from serious diseases. With a strong focus on immunotherapy, cellular therapy, and transformative therapeutic solutions, Atara Biotherapeutics leverages cutting‐edge research into activin, myostatin and other critical growth factors to address complex underlying mechanisms of diseases such as solid tumors, hematologic cancers, and autoimmune disorders.

Core Business and Operational Focus

Atara Biotherapeutics operates in the competitive U.S. healthcare sector with a single, integrated operating segment that is focused entirely on therapeutic development. The company drives its research and development efforts by exploring the intersection of cellular therapies and T-cell engineering. This strategy underscores its commitment to harnessing the body’s own defense mechanisms to create targeted, potent treatments that aim to disrupt disease progression. The company’s approach is built on over a decade of research and clinical exploration, resulting in a pipeline of innovative product candidates that seek to redefine current therapeutic standards.

Innovative Product Candidates and Research Direction

The company has developed multiple innovative product candidates designed to address critical disease pathways. Its portfolio includes T-cell based therapies and advanced platforms such as the CAR T Platform, which highlights the company’s specialization in cellular therapy. In addition to its internally developed candidates, Atara Biotherapeutics has also engaged in strategic collaborations that bolster its research capacity and clinical insights. These collaborations enable the sharing of specialized expertise and resources, further fortifying its development of safe and effective therapeutic solutions.

Scientific Approach and Industry Collaboration

Atara Biotherapeutics’ research is inspired by pioneering discoveries in growth factor biology, which inform its approach to reversing or halting pathological processes underlying various diseases. The company’s commitment to scientific rigor is reflected in its methodical evaluation of molecular targets, including activin and myostatin, that have significant implications for patient care. Collaborations with renowned institutions, such as partnerships with leading cancer centers, play a vital role in validating and accelerating the development of its therapeutic candidates. This synergistic approach fosters an environment of innovation and precision medicine.

Market Position and Competitive Landscape

Positioned within the biotech and healthcare sectors, Atara Biotherapeutics faces both significant opportunities and challenges characteristic of drug development companies. Its niche focus on T-cell and cellular therapies places it among a competitive group of innovators striving to address critical unmet medical needs. What sets Atara apart is the integration of robust scientific research with strategic collaborations and a focused therapeutic pipeline. By concentrating on areas where traditional treatments have reached their limits, the company reinforces its commitment to offering alternative, mechanism-driven therapeutic options that are supported by extensive preclinical and clinical research.

Expertise and Trustworthiness in Therapeutic Development

The depth of experience at Atara Biotherapeutics is demonstrated through its comprehensive approach to treatment development. The company applies advanced scientific methods and leverages ongoing research to refine its product candidates continuously. Its clinical development strategies emphasize safety, efficacy, and reliable delivery of therapeutic benefits to patients. This dedication to scientific excellence, combined with collaborations with esteemed medical institutions, enhances its credibility and positions the company as a knowledgeable entity within the biotherapeutics space.

Key Business Segments and Value Proposition

While the company's operations are centralized within a single reportable segment, its focus encompasses the entire spectrum of therapeutic innovation—from early-stage research to clinical development. This unified operational focus allows Atara Biotherapeutics to efficiently coordinate its research, streamline development processes, and pivot when necessary based on scientific insights. The primary value proposition of the company lies in its ability to translate complex biological insights into practical therapies, thereby offering new hope and treatment avenues for patients facing severe and often life-threatening conditions.

Conclusion

Atara Biotherapeutics Inc presents a comprehensive example of modern biotherapeutic innovation. By maintaining a steadfast focus on cellular and T-cell therapies along with robust scientific and clinical collaborations, the company is systematically addressing some of the most challenging areas in healthcare. Its endeavors are underpinned by scientific expertise, rigorous methodology, and a commitment to developing therapies that are both transformative and rooted in deep molecular insights, reaffirming its position as a significant research-driven entity in the biotherapeutics industry.

Rhea-AI Summary

Atara Biotherapeutics (NASDAQ: ATRA) announced significant milestones for its T-cell immunotherapies in 2021, including FDA Fast Track designation for ATA188 in multiple sclerosis, enhancing its market position. The company aims for tab-cel® to be the first allogeneic therapy approved in the EU for post-transplant lymphoproliferative disease, with decisions expected in 2022. Key presentations will occur at the J.P. Morgan Healthcare Conference on January 12. The company is also advancing CAR T programs targeting solid tumors. 2022 is projected to be a pivotal year for Atara's drug approvals.

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Atara Biotherapeutics (NASDAQ: ATRA) announced the grant of 57,164 restricted stock units and options to purchase 64,925 shares of common stock to newly hired employees. These awards, approved by the Compensation Committee, are part of Atara’s 2018 Inducement Plan, intended as an incentive for new staff. The restricted stock units vest over four years, while stock options vest in a similar timeframe with a ten-year term. The exercise price for stock options is set at $16.89, equal to the stock's closing price on January 3, 2022.

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Atara Biotherapeutics and Be The Match BioTherapies have extended their collaboration to supply healthy donor cells for Atara's off-the-shelf T-cell immunotherapy platform. This partnership aims to support patients with cancer and autoimmune diseases by utilizing Be The Match's extensive registry of over 22 million diverse HLA immune profiles. Atara's lead therapy, tab-cel, is currently under Phase 3 study and has recently submitted a marketing authorization application in the EU, marking a significant step towards availability for patients.

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Atara Biotherapeutics (NASDAQ: ATRA) announced that its President and CEO, Pascal Touchon, will present at the 40th Annual J.P. Morgan Healthcare Conference on January 12, 2022, at 2:15 PM PST / 5:15 PM EST. The presentation will highlight Atara's advancements in T-cell immunotherapy, focusing on their allogeneic Epstein-Barr virus (EBV) T-cell platform aimed at treating cancer and autoimmune diseases. A live audio webcast will be available on their website, with a replay accessible for 30 days.

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Atara Biotherapeutics has announced promising results from its Phase 3 ALLELE study of tabelecleucel (tab-cel) for treating EBV+ PTLD, showing a 50% objective response rate. Among responders, 11 of 19 had a response lasting over six months, with a median time to response of 1.1 months. The one-year survival rate for responders was 89.2%, compared to 32.4% for non-responders. Tab-cel has been well-tolerated, with no new safety concerns, and is under review by the EMA for potential approval.

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Atara Biotherapeutics announced promising results for ATA2271, a CAR T-cell therapy targeting mesothelioma, at the ESMO I-O Congress. Early data show that ATA2271 demonstrates good safety and significant persistence in patients after four weeks, with no severe adverse events reported. The therapy aims to improve outcomes in advanced mesothelioma, where median survival is only 9-17 months despite standard treatments. In vivo studies indicate that ATA2271 can eradicate tumors in mice, highlighting its potential in treating challenging solid tumors.

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Atara Biotherapeutics, Inc. (NASDAQ: ATRA) announced the grant of 21,438 restricted stock units and stock options to newly hired employees, as part of the 2018 Inducement Plan, with the grants dated December 1, 2021. The restricted stock units vest over four years, while the stock options, priced at $17.36 each, also follow a four-year vesting period. This grant is in compliance with Nasdaq Listing Rule 5635(c)(4) and aims to attract talent critical for the company's mission in T-cell immunotherapy.

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Atara Biotherapeutics has announced that the European Medicines Agency (EMA) has fully validated the Marketing Authorization Application (MAA) for its investigational treatment tabelecleucel (tab-cel). This therapy targets Epstein-Barr virus-positive post-transplant lymphoproliferative disease (EBV+ PTLD), a rare and aggressive cancer with no approved options. The MAA will be evaluated by the EMA’s Committee for Medicinal Products for Human Use (CHMP), with a decision expected in the second half of 2022. Tab-cel has shown a 50% objective response rate in clinical trials, demonstrating significant potential for this patient population.

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Atara Biotherapeutics (Nasdaq: ATRA), a leader in T-cell immunotherapy, announced that CEO Pascal Touchon will participate in three virtual conferences. These include the Cowen 5th Annual IO Next Summit on November 15, 2021, at 9:45 a.m. EST, the Stifel 2021 Virtual Healthcare Conference, also on November 15, 2021, at 4:40 p.m. EST, and the Evercore ISI 4th Annual HealthCONx Virtual Conference on November 30, 2021, at 10:05 a.m. EST. Live webcasts will be available on their website, with archived replays accessible for 30 days.

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Atara Biotherapeutics, Inc. (NASDAQ: ATRA) has granted 52,474 restricted stock units and 5,618 stock options to newly hired employees as part of its employee inducement plan. The stock units will vest over four years, while the stock options have a ten-year term with an exercise price of $16.51, aligned with the closing price on the grant date of November 1, 2021. This initiative aims to attract talent under Nasdaq Listing Rule 5635(c)(4).

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FAQ

What is the current stock price of Atara Biotherape (ATRA)?

The current stock price of Atara Biotherape (ATRA) is $6.01 as of April 1, 2025.

What is the market cap of Atara Biotherape (ATRA)?

The market cap of Atara Biotherape (ATRA) is approximately 35.2M.

What is the core focus of Atara Biotherapeutics?

Atara Biotherapeutics focuses on the development of innovative cellular therapies and immunotherapies designed to treat serious diseases, including various cancers and autoimmune disorders. Its work is centered on leveraging advanced T-cell engineering and molecular research to address complex disease mechanisms.

How does Atara Biotherapeutics generate revenue?

The company operates as a single integrated research and development entity, primarily generating revenue through its collaborative partnerships, licensing agreements, and the advancement of its therapeutic candidates through clinical development. Its business model emphasizes innovation and strategic collaborations within the biotech sector.

What types of therapies does Atara Biotherapeutics develop?

The company specializes in developing T-cell based therapies, including those utilizing CAR T platforms, and other cellular-based treatments. Its therapeutic candidates are designed to tackle the underlying biological mechanisms of diseases such as cancers, solid tumors, and autoimmune conditions.

Who are some of Atara Biotherapeutics' key collaborators?

Atara Biotherapeutics collaborates with renowned medical research institutions and cancer centers, enhancing its research and clinical development capabilities. These collaborations facilitate access to specialized expertise, rigorous testing protocols, and shared insights that drive its therapeutic innovation.

How does the company differentiate itself within the competitive biotech industry?

Atara differentiates itself through a focused approach on cellular and T-cell therapies, underpinned by deep scientific research and strategic clinical partnerships. Its commitment to addressing complex disease mechanisms with mechanism-driven therapies sets it apart from more generalized treatment developers.

What is the significance of the company’s research on growth factors?

The research into growth factors such as activin and myostatin is central to Atara’s strategy, as these molecules play a crucial role in disease progression. By targeting these factors, the company aims to modulate the underlying biological processes, offering novel and potentially more effective treatment solutions.

What should investors know about Atara Biotherapeutics' business model?

Investors should note that Atara operates with a singular focus on therapeutic innovation within the biotherapeutics sphere. Its business model is centered on comprehensive R&D, strategic partnerships, and advancing novel therapeutic candidates, which collectively build a foundation of scientific expertise and operational efficiency.
Atara Biotherape

Nasdaq:ATRA

ATRA Rankings

ATRA Stock Data

35.15M
4.56M
21.98%
50.5%
12.2%
Biotechnology
Biological Products, (no Disgnostic Substances)
Link
United States
THOUSAND OAKS