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Atossa Therapeutics Inc - ATOS STOCK NEWS

Welcome to our dedicated page for Atossa Therapeutics news (Ticker: ATOS), a resource for investors and traders seeking the latest updates and insights on Atossa Therapeutics stock.

About Atossa Therapeutics Inc.

Atossa Therapeutics Inc. (Nasdaq: ATOS) is a clinical-stage biopharmaceutical company dedicated to addressing significant unmet medical needs in oncology, with a primary focus on breast cancer treatment and prevention. Headquartered in Seattle, Washington, Atossa leverages cutting-edge science and proprietary technologies to develop innovative therapeutics that aim to improve patient outcomes and quality of life.

Core Business and Focus Areas

The company's flagship program centers on the development of (Z)-endoxifen, a potent and proprietary Selective Estrogen Receptor Modulator (SERM) designed to treat and prevent estrogen receptor-positive (ER+) breast cancer. Unlike traditional tamoxifen therapies, (Z)-endoxifen bypasses liver metabolism, achieving therapeutic concentrations more efficiently and reducing the risk of side effects. This innovative formulation is encapsulated to prevent degradation in the stomach, ensuring higher bioavailability and efficacy.

Atossa's pipeline also includes intraductal microcatheter technology, which enables the targeted delivery of therapies directly to the site of breast cancer. This approach is being explored for the administration of fulvestrant, immunotherapies, and chimeric antigen receptor (CAR) T-cell therapies, offering a potentially transformative method for localized treatment.

Clinical Trials and Research

Atossa is actively advancing multiple clinical trials to validate the safety and efficacy of its therapies. The company's Phase 2 EVANGELINE study focuses on premenopausal women with ER+/HER2- breast cancer, evaluating (Z)-endoxifen as a neoadjuvant treatment. Preliminary data has demonstrated significant tumor shrinkage, reduction in Ki-67 proliferation markers, and a favorable safety profile. Additional Phase 2 trials are investigating (Z)-endoxifen's impact on mammographic breast density and its potential in treating ductal carcinoma in situ (DCIS).

Collaborations with organizations like Eli Lilly and Quantum Leap Healthcare Collaborative further enhance Atossa's clinical capabilities, enabling the exploration of combination therapies such as (Z)-endoxifen with abemaciclib (a CDK 4/6 inhibitor) for high-risk breast cancer patients.

Intellectual Property and Competitive Positioning

Atossa's robust intellectual property portfolio includes multiple issued U.S. patents and numerous pending applications for (Z)-endoxifen and related technologies. This strong patent protection underscores the company's commitment to innovation and provides a competitive edge in the oncology therapeutics market.

Operating within the highly competitive biopharmaceutical industry, Atossa differentiates itself through its focus on targeted therapies, proprietary drug formulations, and patient-centric approaches. The company's emphasis on addressing gaps in current treatment paradigms positions it as a key player in the oncology space.

Market and Growth Potential

The global breast cancer therapeutics market continues to expand, driven by rising incidence rates and advancements in treatment options. Atossa's innovative pipeline addresses critical gaps in this market, particularly for patients with endocrine-resistant tumors or those seeking alternatives to chemotherapy. By focusing on both treatment and prevention, Atossa aims to capture a significant share of this growing market segment.

Challenges and Opportunities

As a clinical-stage company, Atossa faces challenges typical of the biopharmaceutical sector, including high R&D costs, regulatory hurdles, and the need for successful clinical trial outcomes. However, its strategic partnerships, strong intellectual property position, and focus on unmet medical needs provide a solid foundation for long-term growth and success.

Conclusion

Atossa Therapeutics Inc. exemplifies innovation and dedication in the fight against breast cancer. Through its proprietary (Z)-endoxifen and advanced delivery technologies, the company is poised to make a meaningful impact on oncology therapeutics. With a strong clinical pipeline, strategic collaborations, and robust intellectual property, Atossa is well-positioned to address significant unmet medical needs and drive advancements in breast cancer treatment and prevention.

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Atossa Therapeutics, a biopharmaceutical company focused on breast cancer, announces a share repurchase program of up to $10 million. The program reflects confidence in the company's strategic priorities and long-term prospects.
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Atossa Therapeutics has fully enrolled the pharmacokinetic run-in cohort of its Phase 2 EVANGELINE study. The study is testing Atossa's patented SERM, (Z)-endoxifen, and exemestane plus goserelin as a neoadjuvant treatment for pre-menopausal women with ER+/HER2- breast cancer. The goal of the PK run-in cohort is to determine if the 40mg dose delivers optimal plasma concentrations. Data is expected in Q3 of this year.
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FAQ

What is the current stock price of Atossa Therapeutics (ATOS)?

The current stock price of Atossa Therapeutics (ATOS) is $0.741 as of March 3, 2025.

What is the market cap of Atossa Therapeutics (ATOS)?

The market cap of Atossa Therapeutics (ATOS) is approximately 96.0M.

What is the primary focus of Atossa Therapeutics Inc.?

Atossa focuses on developing innovative medicines for oncology, particularly breast cancer treatment and prevention.

What is (Z)-endoxifen?

(Z)-endoxifen is a proprietary Selective Estrogen Receptor Modulator (SERM) designed to treat and prevent estrogen receptor-positive breast cancer.

What makes Atossa's (Z)-endoxifen unique?

(Z)-endoxifen bypasses liver metabolism, achieving therapeutic concentrations efficiently and reducing side effects compared to traditional therapies.

What clinical trials is Atossa currently conducting?

Atossa is conducting Phase 2 trials for (Z)-endoxifen, including the EVANGELINE study for ER+/HER2- breast cancer and studies on mammographic breast density reduction.

How does Atossa differentiate itself in the oncology market?

Atossa differentiates through proprietary drug formulations, targeted delivery technologies, and a focus on unmet medical needs in breast cancer treatment.

What partnerships does Atossa have?

Atossa collaborates with organizations like Eli Lilly and Quantum Leap Healthcare Collaborative to enhance its clinical capabilities.

What challenges does Atossa face as a clinical-stage company?

Atossa faces challenges such as high R&D costs, regulatory hurdles, and the need for successful clinical trial outcomes.

What is Atossa's intellectual property strategy?

Atossa has a robust patent portfolio protecting (Z)-endoxifen and related technologies, ensuring a competitive edge in oncology therapeutics.

What market does Atossa target?

Atossa targets the growing global breast cancer therapeutics market, focusing on areas of unmet medical need.

Where is Atossa Therapeutics headquartered?

Atossa Therapeutics is headquartered in Seattle, Washington.
Atossa Therapeutics Inc

Nasdaq:ATOS

ATOS Rankings

ATOS Stock Data

96.04M
125.71M
0.07%
28.14%
6.94%
Biotechnology
Pharmaceutical Preparations
Link
United States
SEATTLE