Arcturus Therapeutics Holdings Inc. - ARCT STOCK NEWS

Arcturus Therapeutics Holdings Inc. (ARCT) reported its 2020 financial results, showing total revenues of $9.5 million, a significant decline from $20.8 million in 2019. The company incurred a net loss of $72.1 million for the year, compared to $26.0 million in the previous year. Despite this, Arcturus is advancing its ARCT-021 COVID-19 vaccine into Phase 3 trials and has received $46.6 million to support its vaccine stockpiling. The company expects its cash position of $463 million to sustain operations for over two years.

Arcturus Therapeutics Holdings Inc. (Nasdaq: ARCT) announced the acquisition of an exclusive license from Alexion Pharmaceuticals for patent-pending nucleic acid purification technologies. This strategic move aims to enhance the production efficiency of mRNA, critical for the development of vaccines and therapies. With this technology, Arcturus can scale up mRNA production while ensuring higher purity. This acquisition strengthens Arcturus' existing intellectual property portfolio, which is vital for its operations in RNA medicines and vaccines, including COVID-19 and Influenza.

Arcturus Therapeutics Holdings Inc. (Nasdaq: ARCT) will release its financial results for the quarter and year ended December 31, 2020, after market close on March 1, 2021. Following this announcement, a conference call and webcast will take place at 4:30 p.m. ET. Arcturus is focused on developing mRNA medicines and vaccines for infectious diseases, with products targeting COVID-19, Influenza, and rare liver and respiratory diseases. The company utilizes its proprietary LUNAR® and STARR™ technologies and is supported by a strong patent portfolio and various collaborations.

Arcturus Therapeutics Holdings Inc. (Nasdaq: ARCT), a clinical-stage mRNA medicines company, announced its participation in several upcoming investor conferences. Notable events include:

• BIO CEO & Investor Digital Conference: February 12, 2021, at 12:00 p.m. ET
• Raymond James Annual Institutional Investors Conference: March 3, 2021, at 11:40 a.m. ET
• H.C. Wainwright Global Life Sciences Conference: March 9, 2021, at 7:00 a.m. ET
• Barclays Global Healthcare Conference: March 10, 2021, at 1:50 p.m. ET

Arcturus focuses on developing vaccines and treatments for infectious diseases.

Arcturus Therapeutics Holdings Inc. (Nasdaq: ARCT) will engage in a panel discussion at the 13th Annual Biotech Showcase™ Investor Conference.

The discussion, titled COVID-19 Vaccines: All things impacted by COVID-19, will occur on January 11, 2020, at 1:00 p.m. ET. The event can be accessed on-demand from January 12 to March 31, 2020, via the event platform.

Arcturus specializes in mRNA medicines, with a diverse pipeline addressing COVID-19, Influenza, and rare diseases.

Arcturus Therapeutics has received FDA allowance for its IND application regarding the Phase 2 clinical study of its vaccine candidate ARCT-021, based on preceding favorable data from the Phase 1/2 study. The Phase 2 trial will involve 600 participants, evaluating both safety and immunogenicity. The aim is to inform dosing for a prospective Phase 3 study planned for Q2 2021, pending successful results. The ARCT-021 vaccine shows promise for a differentiated profile and may potentially require only a single dose for adequate protection against SARS-CoV-2.

Arcturus Therapeutics Holdings Inc. (Nasdaq: ARCT) has selected ARCT-032, an aerosolized mRNA therapeutic candidate, for Cystic Fibrosis (CF) treatment. This candidate aims to express functional CFTR protein in the lungs, addressing the root cause of CF lung disease. The development is backed by preclinical data showing potential to restore CFTR activity in affected models. The company emphasizes ARCT-032's capability to benefit all CF patients, regardless of genetic mutations, enhancing existing treatment options.

Arcturus Therapeutics Holdings announced approval from the Singapore Health Sciences Authority to conduct a Phase 2 clinical study for its COVID-19 vaccine candidate, ARCT-021. This follows promising results from the Phase 1/2 trial, which demonstrated a robust immune response in all participants. The Phase 2 study aims to identify the best vaccination regimen ahead of a global Phase 3 study anticipated in Q2 2021. Preliminary preclinical data indicated significant protection from SARS-CoV-2 in animal models, further supporting the candidate's potential efficacy.

Arcturus Therapeutics Holdings Inc. (NASDAQ: ARCT) has announced a public offering of 1,365,000 shares priced at $110.00 each, aiming for approximately $150 million in gross proceeds. The offering includes a 30-day option for underwriters to purchase an additional 204,750 shares. The funds are designated for clinical trials and manufacturing its LUNAR-COV19 vaccine. The offering is underpinned by a registration statement filed with the SEC, with closing anticipated around December 10, 2020.