Welcome to our dedicated page for AnaptysBio news (Ticker: ANAB), a resource for investors and traders seeking the latest updates and insights on AnaptysBio stock.
AnaptysBio, Inc. (Nasdaq: ANAB) is a clinical-stage biotechnology company dedicated to developing innovative immunology therapeutics to address unmet medical needs. Founded in 2005, AnaptysBio leverages its proprietary SHM-XEL platform to generate high-affinity therapeutic antibodies by harnessing the natural process of somatic hypermutation (SHM) under controlled conditions. The SHM-XEL platform mimics key features of the human immune system and overcomes the limitations of prior antibody technologies.
Headquartered in San Diego, AnaptysBio is focused on creating a robust pipeline of novel therapeutic antibody candidates targeting autoimmune, inflammatory, and oncology indications. The company boasts a portfolio that includes clinical-stage immune cell modulators such as rosnilimab (PD-1 agonist) and ANB032 (BTLA agonist), both in Phase 2 trials for rheumatoid arthritis (RA), ulcerative colitis (UC), and atopic dermatitis (AD).
AnaptysBio has shown significant progress in its clinical programs. Notably, the company reported positive top-line results from its global Phase 3 GEMINI-1 and GEMINI-2 trials evaluating imsidolimab (IL-36R mAb) for generalized pustular psoriasis (GPP). The results demonstrated rapid clearance of GPP symptoms with a single intravenous dose followed by effective maintenance with monthly subcutaneous doses.
Financially, AnaptysBio is on solid ground, reiterating a cash runway through year-end 2026 with expected year-end 2023 cash and investments of $400 to $410 million. The company's strategic collaborations, including its partnership with GSK for Jemperli (dostarlimab-gxly), provide additional financial support and validation of their therapeutic candidates' commercial potential.
Recently, AnaptysBio announced an exclusive license agreement with Centessa Pharmaceuticals for a BDCA2 modulator portfolio, including ANB101, further expanding its pipeline. The company plans to submit investigational new drug (IND) applications for ANB033 (anti-CD122 antagonist) and ANB101 in 2024.
With a commitment to patient-centric innovation and a strategic approach to partnerships and financial management, AnaptysBio continues to advance its mission of delivering transformative therapies to improve patients' lives globally.
FAQ
What is the current stock price of AnaptysBio (ANAB)?
The current stock price of AnaptysBio (ANAB) is $16.63 as of January 23, 2025.
What is the market cap of AnaptysBio (ANAB)?
The market cap of AnaptysBio (ANAB) is approximately 479.7M.
What does AnaptysBio specialize in?
AnaptysBio specializes in developing therapeutic antibodies for autoimmune, inflammatory, and oncology diseases using its proprietary SHM-XEL platform.
What are the key clinical programs of AnaptysBio?
AnaptysBio's key clinical programs include immune cell modulators like rosnilimab (PD-1 agonist) and ANB032 (BTLA agonist), both in Phase 2 trials for rheumatoid arthritis, ulcerative colitis, and atopic dermatitis.
What recent achievements has AnaptysBio reported?
AnaptysBio recently reported positive top-line results from its Phase 3 GEMINI-1 and GEMINI-2 trials evaluating imsidolimab for generalized pustular psoriasis, demonstrating effective treatment and maintenance.
What are AnaptysBio's financial highlights?
AnaptysBio reiterates a cash runway through year-end 2026, with expected year-end 2023 cash and investments of $400 to $410 million, supported by strategic collaborations and licensing agreements.
What is the SHM-XEL platform?
The SHM-XEL platform is AnaptysBio's proprietary technology that replicates the human immune system's antibody maturation process to generate high-affinity therapeutic antibodies.
Who are AnaptysBio's strategic partners?
AnaptysBio's strategic partners include GSK, with whom they collaborate on the development and commercialization of Jemperli (dostarlimab-gxly) and other therapeutic antibodies.
What is the focus of AnaptysBio's preclinical immune cell modulator portfolio?
AnaptysBio's preclinical immune cell modulator portfolio focuses on advancing candidates like ANB033 (anti-CD122 antagonist) and ANB101 (BDCA2 modulator) for autoimmune and inflammatory diseases.
How does AnaptysBio's SHM-XEL platform benefit their antibody development?
The SHM-XEL platform allows AnaptysBio to generate high-affinity, fully human therapeutic antibodies with optimal properties such as high affinity, function, cross-reactivity, and manufacturability.
What are the recent licensing agreements by AnaptysBio?
AnaptysBio recently entered an exclusive license agreement with Centessa Pharmaceuticals for a BDCA2 modulator portfolio, including the lead asset ANB101.
What are AnaptysBio's plans for 2024?
In 2024, AnaptysBio plans to move ANB033 and ANB101 into clinical development with IND submissions, and continue advancing its clinical trials for rosnilimab and ANB032.