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Ayala Pharm - ADXS STOCK NEWS

Welcome to our dedicated page for Ayala Pharm news (Ticker: ADXS), a resource for investors and traders seeking the latest updates and insights on Ayala Pharm stock.

Ayala Pharmaceuticals (ADXS) is a clinical-stage biotech company pioneering novel cancer immunotherapies and small molecule treatments targeting rare tumors and aggressive cancers. This dedicated news hub provides investors and healthcare professionals with timely updates on clinical developments, regulatory milestones, and strategic partnerships.

Our curated collection features official press releases, trial result announcements, and expert analyses of ADXS's proprietary bacterial-based immunotherapy platform. Key focus areas include advancements in modifying the tumor microenvironment, progress across the company's oncology pipeline, and collaborations advancing next-generation cancer therapies.

Users can expect comprehensive coverage of:
• Clinical trial updates for immunotherapy candidates
• Strategic partnership announcements with biopharma leaders
• Regulatory developments across global markets
• Scientific presentations at major oncology conferences

Bookmark this page for verified updates on Ayala Pharm's progress in developing treatments that harness the immune system to combat challenging cancers. Check regularly for new insights into their dual-platform approach combining bacterial vectors and targeted small molecules.

Rhea-AI Summary

OS Therapies (NYSE-A: OSTX) has entered into an asset purchase agreement to acquire listeria monocytogenes-based immuno-oncology programs and IP assets from Ayala Pharmaceuticals. The acquisition includes a Phase 2 lung cancer and Phase 1 prostate cancer program, along with direct ownership of IP related to OST-HER2 for osteosarcoma.

The deal, valued at $0.5 million in cash and $7.5 million in OSTX shares, eliminates milestone payments and reduces royalty obligations for OST-HER2. The company recently secured $7.1 million in financing at $4.00 per share, providing cash runway into 2026. The monthly burn rate is approximately $0.4M.

OS Therapies plans to request BLA for OST-HER2 in osteosarcoma in Q2 2025, with potential approval and Priority Review Voucher by end of 2025. The company is prohibited from issuing shares for 6 months and suspended equity line usage below $12.00 per share.

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OS Therapies (NYSE-A: OSTX) has entered an asset purchase agreement to acquire listeria monocytogenes-based immuno-oncology programs and IP assets from Ayala Pharmaceuticals. The acquisition includes a Phase 2 lung cancer and Phase 1 prostate cancer program, along with direct ownership of IP related to OST-HER2 for osteosarcoma.

The deal involves a $0.5 million cash payment and $7.5 million in OSTX common shares. The company recently secured $7.1 million in financing at $4.00 per share, providing cash runway into 2026. OS Therapies plans to request BLA for OST-HER2 in osteosarcoma in Q2 2025, with potential FDA approval and Priority Review Voucher by end of 2025.

The agreement eliminates milestone payment obligations and reduces royalty rates for OST-HER2. The company's current burn rate is approximately $0.4M monthly, and they are prohibited from issuing shares for capital raising for 6 months and below $12.00 per share.

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Ayala Pharmaceuticals, a clinical-stage oncology company, has filed a Form 15 with the SEC to deregister its common stock under the Exchange Act and suspend reporting obligations. This move will make the company no longer a public reporting entity once the Form 15 is effective.

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Ayala Pharmaceuticals, Inc. completes the sale of AL102 and AL101 to Immunome, Inc. for $20 million in cash, 2,175,489 shares of Immunome common stock, and potential milestone payments of up to $37.5 million. The sale includes the transfer of specified liabilities related to AL102. Ayala expresses satisfaction with the transaction, highlighting the expertise of Immunome in advancing AL102.
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Ayala Pharmaceuticals Completes Patient Enrollment in Phase 3 RINGSIDE Study for AL102 in Desmoid Tumors
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Immunome, Inc. has entered into a definitive asset purchase agreement with Ayala Pharmaceuticals, Inc. to acquire AL102 and related drug candidate AL101. The agreement includes a $20 million cash payment and $30 million in Immunome common stock, with up to an additional $37.5 million in milestone payments. AL102 is a small molecule gamma secretase inhibitor currently being evaluated in a Phase 3 trial for the treatment of desmoid tumors, showing promising results in terms of tumor reduction and anti-tumor activity.
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Ayala Pharmaceuticals receives FDA Orphan Drug Designation for AL102, a Gamma Secretase Inhibitor (GSI), for the treatment of desmoid tumors (DT). Desmoid tumors are rare connective tissue tumors that affect approximately 1,700 patients in the US annually. AL102 is currently being evaluated in the Phase 3 RINGSIDE study.
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Ayala Pharmaceuticals announces positive results from the RINGSIDE study evaluating AL102 for the treatment of desmoid tumors. The treatment achieved an Overall Response Rate of 83% in the evaluable population, with an 88% reduction in tumor volume and 85% reduction in T2W signal intensity. Phase 3 registration segment of RINGSIDE is enrolling patients globally.
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Ayala Pharmaceuticals completes merger with Biosight, expands product pipeline
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Ayala Pharmaceuticals announces successful End-of-Phase 2 meeting with FDA regarding AL102 for desmoid tumors. Enrollment in Phase 3 of RINGSIDE trial continuing as planned. Definitive merger agreement with Biosight expected to close in Q3 2023.
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NYSE:ADXS

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1.28M
42.63M
0%
10.23%
0.54%
Biotechnology
Healthcare
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United States
Wilmington