Welcome to our dedicated page for Adial Pharmaceuticals news (Ticker: ADIL), a resource for investors and traders seeking the latest updates and insights on Adial Pharmaceuticals stock.
Adial Pharmaceuticals, Inc. (NASDAQ: ADIL) is a clinical-stage biopharmaceutical company focused on developing therapies for the treatment and prevention of addictions and related disorders. News about Adial often centers on the progress of its lead investigational drug, AD04, a genetically targeted serotonin-3 receptor antagonist being developed for Alcohol Use Disorder (AUD) in heavy drinking patients with specific genotypes.
On this page, readers can find coverage of Adial’s clinical development milestones, including updates on the ONWARD™ pivotal Phase 3 trial and preparations for a new Phase 3 adaptive program informed by End of Phase 2 (EOP2) feedback from the U.S. Food and Drug Administration (FDA). Company announcements describe FDA recognition of AUD as an unmet need, support for Adial’s adaptive trial design, and confirmation of primary efficacy endpoints based on heavy drinking days.
Adial’s news flow also highlights its precision medicine strategy. Releases describe a partnership with Genomind to validate a cheek swab genetic test that identifies SNPs in serotonergic system genes such as HTR3A, HTR3B, and SLC6A4, enabling selection of biomarker-positive patients, including those with the AG+ genotype. Additional stories cover intellectual property developments, such as provisional and international patent applications for AD04 that the company expects, once granted, to protect core assets to at least 2045.
Investors and observers can also follow capital markets and listing-related updates, including public offerings of stock and warrants, at-the-market sales agreements, Nasdaq compliance notices, and extensions related to minimum bid price requirements. Together, these items provide context on how Adial is financing and structuring its efforts to advance AD04 and its broader addiction treatment pipeline. Bookmark this page to review new regulatory, clinical, financing, and intellectual property announcements as they are reported.
Adial Pharmaceuticals announced positive pre-clinical results for PNV-5030, indicating its potential to reduce opioid use and alleviate pain. PNV-5030 exhibited over 1000-fold selectivity over the adenosine A1 receptor and demonstrated superior solubility compared to other compounds in its class. In mouse models, PNV-5030 alone provided significant pain relief similar to low doses of morphine, and remarkably, when combined with morphine, it achieved pain relief equivalent to a higher morphine dose. The company plans to advance PNV-5030 into clinical trials in 2022.
Adial Pharmaceuticals (NASDAQ: ADIL; ADILW) has announced that CEO William Stilley will present at the Dawson James Securities Small Cap Growth Conference on October 21, 2021, at 9:45 am ET. The conference will take place at the Wyndham Grand Hotel in Jupiter, Florida, where Stilley will also hold one-on-one meetings with investors. Adial is focused on therapies for addiction, with its lead product AD04 currently in a pivotal Phase 3 clinical trial for Alcohol Use Disorder. Live webcast details can be found on Adial's investor relations website.
Adial Pharmaceuticals (NASDAQ:ADIL;ADILW) has been invited to present at the virtual MicroCap Rodeo Fall Harvest - Best Ideas Conference on October 5, 2021, at 2:30 PM ET. CEO William Stilley will present live, followed by one-on-one meetings during the event. Adial focuses on developing therapies for addiction, with its lead product, AD04, currently in a pivotal Phase 3 clinical trial for Alcohol Use Disorder. The company aims to address various addictive disorders, including Opioid Use Disorder.
Adial Pharmaceuticals (NASDAQ: ADIL; ADILW) has reported that over 50% of patients have completed the ONWARD™ Phase 3 trial for AD04, targeting Alcohol Use Disorder (AUD) based on specific genetic profiles. This 24-week trial, involving 25 sites across Scandinavia and Eastern Europe, aims to analyze the efficacy and safety of AD04. With 303 patients enrolled, the study anticipates a favorable safety profile and is expected to meet its primary endpoint by early 2022. The trial is designed to complement behavioral therapy, enhancing the potential treatment landscape for AUD.
Adial Pharmaceuticals has announced a research collaboration with Dr. Mark Roeser from the University of Virginia to create new adenosine formulations for transdermal application, targeting wound healing. Under the agreement, Purnovate will supply lead compounds while Dr. Roeser's team evaluates them for efficacy and optimal absorption. The University will fund pre-clinical studies, with jointly developed intellectual property. The pressure ulcer wound market is projected to hit $11.2 billion by 2026, highlighting significant market potential for these therapies.
Adial Pharmaceuticals, focused on addiction treatments, announced that CEO William Stilley will present at the H.C. Wainwright 23rd Annual Global Investment Conference from September 13-15, 2021. The presentation will be available on-demand starting September 13 at 7:00 AM Eastern Time. Adial's lead drug, AD04, is being studied in its ONWARD™ Phase 3 trial for Alcohol Use Disorder (AUD) targeting specific genetic profiles, following promising Phase 2b results. The company also explores treatments for other addictions and related disorders.
Adial Pharmaceuticals has successfully closed enrollment for its ONWARD™ Phase 3 trial, achieving 302 patients across 25 clinical sites, exceeding the target of 290. This trial is assessing AD04 for Alcohol Use Disorder (AUD) in patients with specific genetic markers. The company anticipates completing patient dosing by Q1 2022 and looks forward to releasing top-line data shortly thereafter. Preliminary retention rates and safety data indicate AD04 is well-tolerated, potentially positioning it favorably against existing AUD treatments.
Adial Pharmaceuticals (NASDAQ: ADIL; ADILW) has completed enrollment for its ONWARD™ Phase 3 clinical trial, targeting 290 participants with Alcohol Use Disorder (AUD) related to specific genetic markers. The trial is expected to conclude in Q1 2022. CEO William Stilley highlighted strong patient interest, with 33% of screened subjects testing positive for targeted genetics. The market potential for AD04, a novel treatment for AUD, is estimated to exceed $36 billion in the U.S. Additionally, the trial retention rate is high with no serious adverse events reported, enhancing the drug's safety profile.
Adial Pharmaceuticals, Inc. (NASDAQ: ADIL; ADILW) will hold a conference call on August 20, 2021, at 11:00 A.M. Eastern Time to discuss clinical updates and business developments. U.S. callers can join by dialing 844-369-8770, while international participants can dial +1 862-298-0840. A webcast will also be available on the Company’s website. An audio replay will be accessible until September 3, 2021. Adial focuses on developing treatments for addiction, with its lead product, AD04, currently in a pivotal Phase 3 trial for Alcohol Use Disorder.
Adial Pharmaceuticals (NASDAQ: ADIL; ADILW) announces a conference call on August 20, 2021, at 11:00 A.M. ET for a clinical update and business developments. The call can be accessed via telephone or webcast. The Company focuses on therapies for addiction, with its lead product, AD04, currently in a pivotal Phase 3 trial targeting Alcohol Use Disorder (AUD). Prior Phase 2b results showed significant reductions in drinking frequency and quantity without major safety concerns. AD04 may also address other addictive disorders.
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