Welcome to our dedicated page for AC Immune news (Ticker: ACIU), a resource for investors and traders seeking the latest updates and insights on AC Immune stock.
AC Immune SA (ACIU) is a Swiss clinical-stage biopharmaceutical company pioneering precision medicine for neurodegenerative diseases like Alzheimer's. This page provides investors and researchers with centralized access to official news, financial disclosures, and scientific developments directly from the company.
Key resources include earnings reports, clinical trial updates, strategic collaborations, and regulatory milestones. Stay informed on ACIU's progress in developing diagnostic tools and therapies targeting protein misfolding pathologies through its proprietary platforms.
Content spans pipeline advancements, peer-reviewed research highlights, and material business events. Bookmark this page to efficiently track ACIU's contributions to neuroscience innovation and make data-driven decisions based on verified company communications.
AC Immune reported Q2 2024 financial results and provided a corporate update. Key highlights include:
- Exclusive option and license agreement with Takeda for ACI-24.060, with $100 million upfront and potential milestones up to $2.1 billion
- ACI-24.060 ABATE Phase 2 trial in Alzheimer's disease progressing as planned
- ACI-7104.056 VacSYn Phase 2 trial in Parkinson's disease on track for interim data in H2 2024
- Promising preclinical results for ACI-19764, an NLRP3 inhibitor
- Cash balance of CHF 175.2 million, providing a three-year runway
Financial results: Contract revenues of CHF 0.7 million, R&D expenses of CHF 17.1 million, G&A expenses of CHF 4.6 million, and a net loss of CHF 22.8 million for Q2 2024.
AC Immune SA (NASDAQ: ACIU) unveiled a novel class of neurodegenerative disease-fighting drug-candidates called morADC (Morphomer® Antibody Drug Conjugate) at AAIC 2024. This technology combines brain-penetrant Morphomer® small molecules with SupraAntigen® monoclonal antibodies to target toxic proteins in the central nervous system. Key findings include:
1. Significant synergies in blood-brain barrier penetration and protein aggregation inhibition
2. Capability for single or dual-targeting strategies
3. Enhanced anti-aggregation effects compared to parent molecules
4. Multiplied antibody brain exposure
The morADC platform aims to overcome challenges faced by existing modalities and improve clinical outcomes for patients with neurodegenerative diseases.
AC Immune SA (NASDAQ: ACIU) announced that its active-immunotherapy candidate, ACI-35.030 (now called JNJ-2056), has received Fast Track designation from the FDA for Alzheimer's disease treatment. The therapy targets the pathologic form of the Tau protein, phosphorylated Tau (pTau). A Phase 2b clinical trial called ReTain is currently recruiting participants with preclinical Alzheimer's disease.
Key points:
- First active immunotherapy tested in a preclinical AD population
- Potential therapeutic advantages and benefits in convenience and access
- Shown to specifically target toxic form of Tau in Phase 1b/2a clinical testing
- Developed in partnership with Janssen Pharmaceuticals
- ReTain trial is fully funded and conducted by Janssen
AC Immune SA (NASDAQ: ACIU) will present three oral presentations at the Alzheimer's Association International Conference (AAIC 2024) in Philadelphia, showcasing its precision medicine pipeline for neurodegenerative diseases. The presentations will focus on:
1. [18F]ACI-19626, a first-in-class TDP-43-PET tracer
2. ACI-24.060, an active immunotherapy inducing anti-Abeta antibodies
3. morADC (Morphomer®-Antibody Drug Conjugates), a new class of neurodegenerative disease-fighting drugs
Additionally, a poster presentation will compare clinical endpoint progression rates in sporadic Alzheimer's disease and Down Syndrome-related Alzheimer's disease.
The clinical-stage biopharmaceutical company AC Immune (NASDAQ: ACIU) announced its participation in the Jefferies 2024 Global Healthcare Conference in New York, scheduled for June 5-6, 2024.
Company management will engage in a fireside chat on June 5 at 3:30 PM (ET), which can be accessed via webcast. Additionally, AC Immune will hold one-on-one meetings with investors. This involvement aims to highlight their precision medicine advancements for neurodegenerative diseases.
The webcast and an archived replay will be available on AC Immune’s website.
AC Immune reported its first quarter 2024 financial results and corporate update, highlighting a landmark deal with Takeda for ACI-24.060 with $100 million upfront and potential payments of up to $2.1 billion. The ACI-24.060 ABATE Phase 2 trial is on track to report results in Q2 2024, and the ACI-7104.056 VacSYn Phase 2 trial in Parkinson's disease is progressing. The company has a three-year cash runway with CHF 104.8 million. Financially, the company had a cash balance of CHF 104.8 million, R&D expenses of CHF 15.2 million, and reported a net loss of CHF 17.9 million for the quarter.
AC Immune and Takeda have signed an exclusive option and license agreement for ACI-24.060, an active immunotherapy targeting Amyloid Beta for Alzheimer's disease. Takeda will pay AC Immune $100 million upfront, with additional potential milestones totaling around $2.1 billion. AC Immune will host a conference call and webcast to discuss the agreement.
