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Overview
Absci Corp (ABSI) is a cutting-edge synthetic biology company leveraging generative AI and scalable wet lab technologies to revolutionize the discovery and design of novel biologics. With its Integrated Drug Creation™ platform, Absci seamlessly unifies biological drug discovery and cell line development, enabling the rapid and efficient design of candidate therapeutics.
Core Business and Technological Expertise
At its core, Absci is dedicated to transforming the drug discovery process by combining massive data inputs and advanced AI algorithms with state-of-the-art laboratory validation techniques. This dual approach allows the company to screen billions of cells per week and validate AI-designed antibodies in a matter of weeks. The platform optimizes multiple drug characteristics simultaneously, which is essential for enhancing therapeutic benefit and streamlining the time to clinic.
Collaborative Ecosystem
Absci's robust collaboration model forms a significant part of its strategy. By partnering with leading academic institutions, global pharmaceutical companies, and innovative technology firms, the company enhances the development of novel therapeutic assets in various fields such as oncology, immunology, and even animal health. These partnerships not only bolster its research capabilities but also position Absci as a versatile player in today’s competitive biotech landscape.
Market Position and Competitive Landscape
Operating at the confluence of AI and synthetic biology, Absci stands out for its ability to rapidly generate and validate candidate therapies. Unlike traditional methods that often involve slower, isolated processes, its integrated platform allows for multiple drug attributes to be optimized concurrently. Such innovation is increasingly significant among peers in the biotech sector, where speed and efficiency in research are critical competitive differentiators. The collaborative ventures with renowned entities add layers of validation and authority to its approach, firmly positioning it within a competitive yet ever-evolving market.
Operational Model and Value Proposition
Absci’s operational model is built around a data-first philosophy that harnesses both computational power and reliable lab-based experimentation. This holistic approach reduces the traditional gap between bioinformatics design and biological validation. By embracing generative AI, the company is able to design antibodies de novo and rapidly transition promising candidates from digital models to wet lab proofs-of-concept. The company’s methodology not only accelerates the pipeline but also increases the probability of identifying successful therapeutic candidates.
Key Differentiators
- Generative AI Drug Creation: Absci’s AI models enable the design of novel biologic therapeutics with unprecedented speed and precision.
- Integrated Workflow: The simultaneous integration of biologic discovery with cell line development streamlines research and enhances therapeutic potential.
- Collaborative Partnerships: Strategic alliances with leading pharma companies, research institutes, and technology firms underpin its diverse research pipeline and reinforce its industry credibility.
Industry Relevance
Within the broader synthetic biology and biotechnology sectors, Absci embodies the drive toward data-driven discovery and rapid therapeutic development. The company’s innovative approach eliminates many inefficiencies inherent in conventional drug discovery processes. By employing a technology-forward strategy, Absci creates a scalable model that is not only applicable in human therapeutics but is also expanding into adjacent markets such as veterinary medicine.
Conclusion
In summary, Absci Corp represents a paradigm shift in the biopharmaceutical industry. Its pioneering use of generative AI combined with integrated wet lab validation sets a new standard for drug discovery. The comprehensive approach to optimizing multiple facets of drug development offers investors and industry analysts deep insights into the future of biologic therapeutics, firmly establishing Absci as an innovative force in synthetic biology and AI-enabled drug creation.
Absci (Nasdaq: ABSI), a data-first generative AI drug creation company, has announced its participation in the 43rd Annual J.P. Morgan Healthcare Conference in San Francisco. The company's management will deliver a presentation on Wednesday, January 15th at 4:30 p.m. Pacific Time (7:30 p.m. Eastern Time).
Investors and interested parties can access both the live presentation and archived webcast through Absci's investor relations website at investors.absci.com.
Absci (NASDAQ: ABSI) announced significant updates across its pipeline and AI platform at its 2024 R&D Day. The company highlighted progress on several drug candidates:
ABS-201, a novel anti-PRLR antibody for androgenic alopecia, demonstrated improved hair regrowth compared to minoxidil in preclinical trials, targeting a market of approximately 80 million individuals in the U.S. Phase 1 trials are expected to begin in 1H 2026.
ABS-101, an anti-TL1A antibody, showed promising safety profile in 13-week toxicology studies, with Phase 1 trials anticipated in 1H 2025. The company also reported progress on ABS-301 for immuno-oncology and ABS-501, a novel anti-HER2 antibody. Additionally, Absci achieved a breakthrough in designing antibodies targeting the HIV 'caldera' region, potentially advancing universal HIV vaccine development.
Absci (Nasdaq: ABSI), a data-first generative AI drug creation company, announced its participation in the 36th Annual Piper Sandler Healthcare Conference in New York. The company's Founder & CEO Sean McClain will join a panel discussion on 'The Promise of AI in Drug Development' scheduled for Thursday, December 5th at 2:00 p.m. Eastern Time. Those interested in attending can request registration details through their Piper Sandler representative.
Absci (ABSI) reported Q3 2024 financial results and business updates. Revenue increased to $1.7 million from $0.7 million year-over-year. Net loss widened to $27.4 million from $22.0 million in Q3 2023. The company delivered AI-designed antibody sequences to AstraZeneca, meeting their first milestone, and entered a new collaboration with Twist Bioscience. R&D expenses increased to $18.0 million from $11.0 million YoY. Cash position stands at $127.1 million, expected to fund operations into first half of 2027. The company reduced its expected cash use for 2024 to $75 million from $80 million previously.
Absci (Nasdaq: ABSI), a data-first generative AI drug creation company, has announced its upcoming 2024 R&D Day scheduled for December 12th in New York City. The event will run from 9:00 a.m. to approximately 12:00 p.m. Eastern Time, featuring presentations from Absci's leadership team and guest speakers, followed by an interactive Q&A session. Interested participants can access both live and archived webcasts of the event through the company's investor relations website at investors.absci.com.
Absci (NASDAQ: ABSI) and Twist Bioscience announced a collaboration to design a novel therapeutic using generative AI. The partnership combines Absci's AI drug creation platform with Twist's DNA synthesis technology to accelerate pharmaceutical R&D. The companies will develop a therapeutic candidate against an undisclosed target, utilizing Absci's AI de novo design capabilities and Twist's silicon-based synthesis platform, including Multiplexed Gene Fragments for testing antibody candidates. Both companies plan to seek a partner for clinical development and commercialization. This program adds to Absci's portfolio of collaborations with companies like AstraZeneca and Merck.
Absci (Nasdaq: ABSI), a data-first generative AI drug creation company, has announced its participation in multiple investor conferences in November 2024. The schedule includes the Truist Securities BioPharma Symposium in New York, Guggenheim Securities Inaugural Healthcare Innovation Conference in Boston, UBS Global Healthcare Conference in California, Stifel 2024 Healthcare Conference in New York, and Jefferies London Healthcare Conference in the UK. The company will participate in fireside chats and host one-on-one meetings. Live and archived webcasts will be available on Absci's investor relations website.
Absci (Nasdaq: ABSI), a data-first generative AI drug creation company, has announced it will report business updates and financial and operating results for the third quarter of 2024 before market open on Tuesday, November 12, 2024. The company's management will host a conference call and webcast at 8:00 a.m. Eastern Time / 5:00 a.m. Pacific Time on the same day to discuss developments, results, and outlook.
Investors can access the live audio webcast on Absci's investor relations website at investors.absci.com. The webcast will also be archived for later replay. This announcement indicates Absci's commitment to transparency and shareholder communication, providing an opportunity for investors to gain insights into the company's performance and future prospects.
Absci (Nasdaq: ABSI), a data-first generative AI drug creation company, has announced its participation in three upcoming investor conferences in September 2024:
- Morgan Stanley 22nd Annual Global Healthcare Conference: Fireside chat on September 5th at 5:35 p.m. ET
- Citi 2024 Global TMT Conference: Fireside chat on September 6th at 8:20 a.m. ET
- H.C. Wainwright 26th Annual Global Investment Conference: Fireside chat on September 10th at 12:00 p.m. ET
Interested parties can access live and archived webcasts of these events on Absci's investor relations website at investors.absci.com.
Absci (Nasdaq: ABSI) reported Q2 2024 financial results and business updates. Key highlights include:
1. Non-human primate studies for ABS-101 showed 2-3x extended half-life compared to antibodies in clinical development.
2. Collaboration with Memorial Sloan Kettering Cancer Center to develop up to six novel oncology therapeutics.
3. Revenue decreased to $1.3 million from $3.4 million in Q2 2023.
4. Net loss reduced to $24.8 million from $41.7 million in Q2 2023.
5. Cash position of $145.2 million as of June 30, 2024.
6. Company expects to initiate Phase 1 clinical studies for ABS-101 in early 2025.