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AbCellera Biologics Inc. (Nasdaq: ABCL) is a trailblazer in the Canadian biotechnology sector, specializing in the accelerated discovery of monoclonal antibody (mAbs) therapeutics. The company leverages cutting-edge microfluidic technology to address the complexities of identifying and developing effective antibodies from single immune cells. This breakthrough approach enables high-throughput analysis, expediting the process of bringing new therapies to patients who need them the most.
AbCellera's core business revolves around its integrated antibody discovery and development platform, which combines proprietary technologies, expert teams, and data-driven methodologies. This platform empowers AbCellera to identify and optimize clinical candidates with unparalleled speed and precision, offering a competitive edge to its partners. The company's strategic partnerships span emerging biotechs and leading pharmaceutical firms, aimed at tackling the most challenging issues in drug development.
Among its recent achievements, AbCellera presented groundbreaking data on its T-cell engager (TCE) programs at the Society for Immunotherapy of Cancer Annual Meeting. The innovative TCE platform includes novel CD3-binding antibodies engineered to fine-tune T-cell responses, thereby enhancing the efficacy and safety profiles of cancer therapies. AbCellera's research is breaking new ground in immuno-oncology, with promising results in targeting prostate-specific membrane antigen (PSMA) and melanoma-associated antigen 4 (MAGE-A4).
Financially, AbCellera reported $38 million in total revenue for 2023, alongside significant investments in research and development. Despite a net loss that reflects its aggressive growth strategy, the company remains well-positioned with approximately $1 billion in available liquidity. This financial stability supports continued innovation and expansion, particularly in advancing internal programs and strategic partnerships.
AbCellera is committed to overcoming traditional barriers in antibody drug discovery, aiming to deliver better medicines faster. The company's robust pipeline and forward-looking strategies make it a significant player in the biotech industry, poised to make a lasting impact on global healthcare.
AbCellera (Nasdaq: ABCL) will release its first-quarter 2021 financial results on May 13, 2021, and host an earnings conference call at 2:00 p.m. PT (5:00 p.m. ET). A live webcast will be accessible via the Investor Relations website, with a replay available afterward.
AbCellera specializes in antibody discovery by analyzing immune systems, partnering with various drug developers to streamline drug development processes.
AbCellera (Nasdaq: ABCL) and Empirico Inc. announced a strategic collaboration focusing on multi-target drug discovery. The partnership utilizes advanced technologies and data analysis to identify therapeutic targets and antibodies. Empirico will select up to five targets using its Precision Insights Platform, while AbCellera will leverage its AI for antibody discovery. AbCellera will receive research payments and may earn royalties from developed products. The collaboration aims to address challenges in drug development by linking human genetics to therapy insights.
AbCellera (Nasdaq: ABCL) announced the publication of preclinical data in Science Translational Medicine demonstrating the high potency of bamlanivimab (LY-CoV555) against SARS-CoV-2. The findings indicate that bamlanivimab significantly reduces viral load post-exposure, highlighting its potential to decrease viral shedding and transmission. In clinical trials, bamlanivimab has shown to cut hospitalizations by 70% in high-risk COVID-19 patients. It has also been authorized in over 15 countries and supports ongoing efforts to develop next-generation antibodies.
AbCellera (Nasdaq: ABCL) has announced an expanded collaboration with Gilead Sciences that includes a multi-year, multi-target antibody discovery initiative and access to AbCellera's Trianni Mouse® technology. The agreement entails upfront payments, milestone payments, and royalties based on the commercialization of antibodies developed. AbCellera will produce panels of antibodies for up to eight new targets across various indications, enhancing drug development efficiency with advanced technology.
AbCellera (Nasdaq: ABCL) announced positive results from a Phase 3 trial of bamlanivimab and etesevimab, reducing COVID-19-related hospitalizations and deaths by 87% in high-risk patients. No deaths occurred in the treatment group, while 14 were reported in the placebo cohort. Milestones achieved include Emergency Use Authorization from the FDA and expanded access in the EU. The study involved 769 patients, showing a safety profile consistent with earlier trials. Bamlanivimab was the first COVID-19 therapeutic candidate to receive FDA EUA.
AbCellera (Nasdaq: ABCL) announced a positive scientific opinion from the EMA's CHMP for the use of bamlanivimab alone and in combination with etesevimab for treating COVID-19 in high-risk patients aged 12 and older. This recommendation allows EU member states to make informed decisions on therapy usage before market authorization. The CHMP opinion was backed by positive results from Eli Lilly's BLAZE-1 trial, showing a 70% reduction in hospitalization rates. Bamlanivimab has also received authorization in over 10 countries and generated $871 million in sales in 2020.
AbCellera (NASDAQ: ABCL) will present at the 10th Annual SVB Leerink Global Healthcare Conference on February 25, 2021, at 1:20 p.m. PT. A live audio webcast will be accessible on AbCellera’s Investor Relations website, with a replay available afterward. AbCellera is a technology company focused on discovering antibodies from natural immune systems, partnering with drug developers to accelerate drug development and reduce costs. The press release includes forward-looking statements about potential risks and uncertainties in their business operations.
AbCellera (Nasdaq: ABCL) has appointed Ester Falconer, Ph.D., as Chief Technology Officer effective January 28, 2021. Dr. Falconer will oversee the company's strategy to enhance therapeutic antibody discovery technologies. Previously, she led R&D at AbCellera and contributed significantly to the development of the COVID-19 therapeutic bamlanivimab. Her appointment is expected to strengthen leadership and innovation within the company. Dr. Falconer has been with AbCellera since 2015, advancing through various roles, and holds a Ph.D. in genetics and cell biology.
AbCellera (Nasdaq: ABCL) announced that bamlanivimab (LY-CoV555) 700 mg, developed with Eli Lilly, received Emergency Use Authorization (EUA) from the FDA for treating mild to moderate COVID-19 in high-risk patients. The therapy demonstrated a 70% reduction in hospitalizations in the Phase 3 BLAZE-1 trial, which involved over 1,000 patients. Lilly plans to manufacture over 250,000 doses in Q1 2021. Bamlanivimab, developed from an antibody discovered in a recovered COVID-19 patient, is part of AbCellera's pandemic response efforts, identifying over 2,300 unique antibodies.
AbCellera (Nasdaq: ABCL) is set to announce its fourth-quarter and full-year 2020 financial results on March 29, 2021, after U.S. market close. An earnings conference call will follow at 2:00 p.m. PT (5:00 p.m. ET). The live webcast will be accessible via AbCellera’s Investor Relations website, with a replay available post-call.
AbCellera specializes in discovering and analyzing antibodies for drug development, collaborating with various drug developers to streamline processes and reduce costs.
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