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Agilent Announces the Innovative Mito-rOCR Assay Kit for Mitochondrial Research

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Agilent Technologies (NYSE: A) has launched the Mito-rOCR Assay Kit, a new solution for analyzing mitochondrial function in cells. This innovative kit measures cells' relative oxygen consumption rate (rOCR), providing insights into mitochondrial health and performance. The assay is compatible with various fluorescent plate readers and multimode imagers, including the BioTek Cytation series. Key features include direct compound reconstitution in assay medium, reversibility, and integration with Agilent Seahorse Analytics cloud-based software for streamlined data analysis. The kit aims to democratize cell analysis by making sophisticated mitochondrial research accessible to researchers of all skill levels.

Agilent Technologies (NYSE: A) ha lanciato il Mito-rOCR Assay Kit, una nuova soluzione per analizzare la funzione mitocondriale nelle cellule. Questo kit innovativo misura il tasso relativo di consumo di ossigeno delle cellule (rOCR), fornendo approfondimenti sulla salute e sulle prestazioni mitocondriali. L'analisi è compatibile con vari lettori di piastre fluorescenti e imagers multimodali, inclusa la serie BioTek Cytation. Le caratteristiche principali includono la ricostituzione diretta dei composti nel mezzo di analisi, la reversibilità e l'integrazione con il software basato su cloud Agilent Seahorse Analytics per un'analisi dei dati semplificata. Il kit mira a sdoganare l'analisi cellulare rendendo la ricerca mitocondriale sofisticata accessibile a ricercatori di tutti i livelli di abilità.

Agilent Technologies (NYSE: A) ha lanzado el Mito-rOCR Assay Kit, una nueva solución para analizar la función mitocondrial en las células. Este kit innovador mide la tasa de consumo de oxígeno relativa de las células (rOCR), proporcionando información sobre la salud y el rendimiento mitocondrial. El ensayo es compatible con varios lectores de placas fluorescentes y en modo múltiple, incluida la serie BioTek Cytation. Las características clave incluyen la reconstitución directa de compuestos en el medio de ensayo, la reversibilidad y la integración con el software en la nube Agilent Seahorse Analytics para un análisis de datos optimizado. El kit tiene como objetivo democratizar el análisis celular haciendo que la investigación mitocondrial sofisticada sea accesible para investigadores de todos los niveles de habilidad.

Agilent Technologies (NYSE: A)는 세포에서 미토콘드리아 기능을 분석하기 위한 새로운 솔루션인 Mito-rOCR Assay Kit를 출시했습니다. 이 혁신적인 키트는 세포의 상대적 산소 소비 속도(rOCR)를 측정하여 미토콘드리아 건강과 성능에 대한 통찰력을 제공합니다. 이 분석법은 BioTek Cytation 시리즈를 포함한 다양한 형광 플레이트 리더 및 멀티모드 이미저와 호환됩니다. 주요 기능으로는 분석 매체에서의 직접적인 화합물 재구성, 가역성 및 Agilent Seahorse Analytics 클라우드 기반 소프트웨어와의 통합을 통한 데이터 분석의 간소화가 있습니다. 이 키트는 고급 미토콘드리아 연구를 모든 기술 수준의 연구자들이 접근할 수 있도록 하여 세포 분석을 민주화하는 것을 목표로 하고 있습니다.

Agilent Technologies (NYSE: A) a lancé le Mito-rOCR Assay Kit, une nouvelle solution pour analyser la fonction mitochondriale dans les cellules. Ce kit innovant mesure le taux de consommation d'oxygène relatif des cellules (rOCR), offrant des perspectives sur la santé et les performances mitochondriales. L'essai est compatible avec divers lecteurs de plaques fluorescentes et des imageurs multimodes, y compris la série BioTek Cytation. Les caractéristiques clés incluent la reconstitution directe des composés dans le milieu d'essai, la réversibilité et l'intégration avec le logiciel basé sur le cloud Agilent Seahorse Analytics pour une analyse de données rationalisée. Le kit vise à démocratiser l'analyse cellulaire en rendant la recherche mitochondriale sophistiquée accessible aux chercheurs de tous niveaux de compétences.

Agilent Technologies (NYSE: A) hat das Mito-rOCR Assay Kit auf den Markt gebracht, eine neue Lösung zur Analyse der mitochondrialen Funktion in Zellen. Dieses innovative Kit misst die relative Sauerstoffverbrauchsrate der Zellen (rOCR) und bietet Einblicke in die Gesundheit und Leistung der Mitochondrien. Der Test ist mit verschiedenen fluoreszierenden Plattenlesern und multimodalen Bildgebungsgeräten, einschließlich der BioTek Cytation-Serie, kompatibel. Zu den Hauptmerkmalen gehören die direkte Rekonstruktion von Verbindungen im Assay-Medium, die Reversibilität und die Integration mit der cloudbasierten Software Agilent Seahorse Analytics für eine vereinfachte Datenanalyse. Das Kit zielt darauf ab, die Zellanalyse zu demokratisieren, indem es anspruchsvolle mitochondriale Forschung für Forscher aller Fähigkeitsstufen zugänglich macht.

Positive
  • Introduction of new product expanding company's metabolic analysis solutions portfolio
  • Product addresses market demand for easy-to-use assays compatible with various fluorescence plate readers
  • Integration with existing Agilent Seahorse Analytics platform enhances product ecosystem
Negative
  • None.

Insights

The launch of Agilent's Mito-rOCR Assay Kit represents an incremental product advancement rather than a significant market-moving event. While the kit offers improved accessibility for mitochondrial research, its immediate financial impact is likely to be minimal relative to Agilent's $38.4B market cap and diverse product portfolio.

The key innovation lies in the kit's versatility and ease of use, compatible with various fluorescent plate readers and offering streamlined data analysis through cloud-based software. However, this is more of a strategic positioning move to expand market reach rather than a breakthrough that would significantly impact revenue streams.

The product enhances Agilent's existing metabolic analysis portfolio but isn't likely to materially affect near-term financial performance or stock valuation. Long-term benefits may include increased market penetration in academic and research settings, though this would be gradual rather than transformative.

Streamlined solution for mitochondrial assessment democratizes cell analysis making it accessible to more researchers

SANTA CLARA, Calif.--(BUSINESS WIRE)-- Agilent Technologies Inc. (NYSE: A) announces the new Mito-rOCR Assay Kit. This easy and streamlined end-to-end solution makes sophisticated analysis of mitochondrial function available to researchers of all skill levels. With this cost-effective and versatile kit, researchers can easily incorporate functional assessment of relative mitochondrial respiration into their cell physiology and disease pathology studies.

Mitochondria are central to energy production processes that drive cellular activity, and mitochondrial dysfunction is linked to numerous diseases and conditions. The Mito-rOCR assay enables more researchers to explore this crucial aspect of biology with accuracy and ease. The assay can be used with various compatible fluorescent plate readers and multimode imagers that meet its requirements for sensitivity, detection capabilities, and environmental control.

For example, the BioTek Cytation series of fluorescence plate readers and multimode imagers are ideal for the Mito-rOCR assay. Their advanced software allows them to handle various applications, maintain optimal conditions, and automate processes, making them reliable and adaptable for different research needs.

The Mito-rOCR assay measures cells’ relative oxygen consumption rate (rOCR), enabling sensitive detection of changes in mitochondrial function. This approach offers thorough insights into mitochondrial health and performance. With the Mito-rOCR Assay Kit, compounds are reconstituted directly in the assay medium, eliminating the need for additional solvents.

Notably, the assay is also reversible; the reagent remains outside the cells to prevent interference with cellular processes and can be easily removed to allow further downstream analyses. Data analysis is conducted using the Mito-rOCR Analysis Module within Agilent Seahorse Analytics. This cloud-based software makes importing data, linearizing signals, calculating slopes, and generating data tables and bar charts easy and streamlined.

Chris Braun, associate vice president of Marketing in Agilent’s Cell Analysis Division, commented on the importance of this announcement. “The Agilent Mito-rOCR Assay Kit was developed in direct response to customer feedback, as they told us they needed an easy-to-use assay that works with various fluorescence plate readers. The Mito-rOCR Assay Kit delivers this with a robust assay that supports multiplexing. This innovative assay democratizes the measurement of relative oxygen consumption rate in live cells, enabling more researchers to study cellular respiration and related biological processes.”

A key part of Agilent’s family of metabolic analysis solutions, the Mito-rOCR Assay Kit further expands Agilent’s broad range of uniquely enabling tools for interrogating cellular metabolism. These tools deliver a functional view of cell metabolism to more scientists, facilitating scientific advancement and accelerating discovery across critical areas of biological investigation.

About Agilent Technologies

Agilent Technologies Inc. (NYSE: A) is a global leader in analytical and clinical laboratory technologies, delivering insights and innovation that help our customers bring great science to life. Agilent’s full range of solutions includes instruments, software, services, and expertise that provide trusted answers to our customers' most challenging questions. The company generated revenue of $6.85 billion in fiscal 2022 and employs approximately 18,000 people worldwide. Information about Agilent is available at www.agilent.com. To receive the latest Agilent news, please subscribe to the Agilent Newsroom. Follow Agilent on LinkedIn and Facebook.

Media Contact

Naomi Goumillout

Agilent Technologies

+1.978.314.1862

naomi.goumillout@agilent.com

Source: Agilent Technologies Inc.

FAQ

What is the new Mito-rOCR Assay Kit announced by Agilent (NYSE: A)?

The Mito-rOCR Assay Kit is a new solution for analyzing mitochondrial function that measures cells' relative oxygen consumption rate (rOCR), making sophisticated analysis accessible to researchers of all skill levels.

Which plate readers are compatible with Agilent's (NYSE: A) new Mito-rOCR Assay Kit?

The Mito-rOCR Assay Kit is compatible with various fluorescent plate readers and multimode imagers that meet sensitivity, detection, and environmental control requirements, including the BioTek Cytation series.

How does Agilent's (NYSE: A) Mito-rOCR Assay Kit analyze data?

Data analysis is conducted using the Mito-rOCR Analysis Module within Agilent Seahorse Analytics, a cloud-based software that handles data importing, signal linearization, slope calculations, and generates data tables and charts.

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