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Plus Therapeutics Inc Financials

PSTV
Source SEC Filings (10-K/10-Q) Updated Dec 31, 2025 Currency USD FYE December

This page shows Plus Therapeutics Inc (PSTV) financial statements, including the income statement, balance sheet, cash flow statement, and key financial ratios. View 17 years of annual fundamentals and quarterly data, with year-over-year growth rates and compound annual growth rates (CAGR). All figures are derived from SEC filings (10-K and 10-Q reports).

Financial Health Signals

Profitability Growth Leverage Liquidity Cash Flow Returns 12 / 100
Financial Profile 12/100

Based on FY2025 annual data. Scores normalized against common benchmarks. How we calculate these scores

Profitability
0

Plus Therapeutics Inc has an operating margin of -293.5%, meaning the company retains $-293 of operating profit per $100 of revenue. This below-average margin results in a low score of 0/100, suggesting thin profitability after operating expenses. This is down from -252.3% the prior year.

Growth
16

Plus Therapeutics Inc's revenue declined 10.5% year-over-year, from $5.8M to $5.2M. This contraction results in a growth score of 16/100.

Leverage
39

Plus Therapeutics Inc has a moderate D/E ratio of 3.09. This balance of debt and equity financing earns a leverage score of 39/100.

Liquidity
20

Plus Therapeutics Inc's current ratio of 1.23 means current assets barely cover short-term liabilities. This tight liquidity results in a low score of 20/100, which could limit financial flexibility.

Cash Flow
0

While Plus Therapeutics Inc generated -$20.8M in operating cash flow, capex of $67K consumed most of it, leaving -$20.8M in free cash flow. This results in a low score of 0/100, reflecting heavy capital investment rather than weak cash generation.

Returns
0

Plus Therapeutics Inc generates a -560.2% ROE, indicating limited profit relative to shareholders' investment. This results in a returns score of 0/100.

Piotroski F-Score Weak
3/9

Plus Therapeutics Inc passes 3 of 9 financial strength tests. 2 of 4 profitability signals pass, 1 of 3 leverage/liquidity signals pass, neither operating efficiency signal passes.

Earnings Quality Low Quality
0.93x

For every $1 of reported earnings, Plus Therapeutics Inc generates $0.93 in operating cash flow (-$20.8M OCF vs -$22.4M net income). This low ratio suggests earnings are primarily driven by accounting accruals rather than cash generation, which may not be sustainable.

Interest Coverage At Risk
-27.9x

Plus Therapeutics Inc earns $-27.9 in operating income for every $1 of interest expense (-$15.3M vs $548K). This narrow margin raises concern about the company's ability to service its debt if operating income declines.

Key Financial Metrics

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Earnings & Revenue

Revenue
$5.2M
YoY-10.5%
10Y CAGR+0.7%

Plus Therapeutics Inc generated $5.2M in revenue in fiscal year 2025. This represents a decrease of 10.5% from the prior year.

EBITDA
-$14.9M
YoY-7.5%

Plus Therapeutics Inc's EBITDA was -$14.9M in fiscal year 2025, measuring earnings before interest, taxes, depreciation, and amortization. This represents a decrease of 7.5% from the prior year.

Net Income
-$22.4M
YoY-72.5%

Plus Therapeutics Inc reported -$22.4M in net income in fiscal year 2025. This represents a decrease of 72.5% from the prior year.

EPS (Diluted)
$-0.29

Plus Therapeutics Inc earned $-0.29 per diluted share (EPS) in fiscal year 2025. This represents an increase of 87.6% from the prior year.

Cash & Balance Sheet

Free Cash Flow
-$20.8M
YoY-94.8%

Plus Therapeutics Inc generated -$20.8M in free cash flow in fiscal year 2025, representing cash available after capex. This represents a decrease of 94.8% from the prior year.

Cash & Debt
$4.3M
YoY+5500.0%
5Y CAGR-12.6%
10Y CAGR-11.4%

Plus Therapeutics Inc held $4.3M in cash against $0 in long-term debt as of fiscal year 2025.

Dividends Per Share
N/A
Shares Outstanding
139M

Plus Therapeutics Inc had 139M shares outstanding in fiscal year 2025. This represents an increase of 2251.9% from the prior year.

Margins & Returns

Gross Margin
N/A
Operating Margin
-293.5%
YoY-41.1pp
10Y CAGR+22.5pp

Plus Therapeutics Inc's operating margin was -293.5% in fiscal year 2025, reflecting core business profitability. This is down 41.1 percentage points from the prior year.

Net Margin
-429.4%
YoY-206.6pp
10Y CAGR-42.0pp

Plus Therapeutics Inc's net profit margin was -429.4% in fiscal year 2025, showing the share of revenue converted to profit. This is down 206.6 percentage points from the prior year.

Return on Equity
-560.2%
5Y CAGR-288.3pp
10Y CAGR-406.6pp

Plus Therapeutics Inc's ROE was -560.2% in fiscal year 2025, measuring profit generated per dollar of shareholder equity.

Capital Allocation

R&D Spending
$8.4M
YoY-20.8%
5Y CAGR+25.4%
10Y CAGR-7.9%

Plus Therapeutics Inc invested $8.4M in research and development in fiscal year 2025. This represents a decrease of 20.8% from the prior year.

Share Buybacks
N/A
Capital Expenditures
$67K
YoY-54.1%
10Y CAGR-19.8%

Plus Therapeutics Inc invested $67K in capex in fiscal year 2025, funding long-term assets and infrastructure. This represents a decrease of 54.1% from the prior year.

PSTV Income Statement

Metric Q4'25 Q3'25 Q2'25 Q1'25 Q4'24 Q3'24 Q2'24 Q1'24
Revenue $1.4M-2.1% $1.4M+0.5% $1.4M+31.3% $1.1M-25.0% $1.4M-3.0% $1.5M+13.8% $1.3M-23.7% $1.7M
Cost of Revenue N/A N/A N/A N/A N/A N/A N/A N/A
Gross Profit N/A N/A N/A N/A N/A N/A N/A N/A
R&D Expenses $2.9M+20.7% $2.4M+95.5% $1.2M-29.0% $1.8M-19.7% $2.2M-23.5% $2.9M+3.1% $2.8M+0.4% $2.8M
SG&A Expenses $4.2M+21.1% $3.4M+104.7% $1.7M-40.8% $2.8M-9.2% $3.1M+30.4% $2.4M+8.8% $2.2M-0.5% $2.2M
Operating Income -$5.7M-28.1% -$4.5M-191.4% -$1.5M+56.5% -$3.5M+9.3% -$3.9M-2.7% -$3.8M-2.8% -$3.7M-12.1% -$3.3M
Interest Expense N/A N/A N/A $548K+861.4% $57K-6.6% $61K+125.9% $27K-20.6% $34K
Income Tax N/A N/A N/A N/A N/A N/A N/A N/A
Net Income -$5.7M-29.2% -$4.4M-185.9% $5.2M+129.6% -$17.4M-345.8% -$3.9M-35.8% -$2.9M+2.2% -$2.9M+9.8% -$3.3M
EPS (Diluted) N/A $-0.04 $-0.01+99.2% $-1.19 N/A $-0.37+47.9% $-0.71+5.3% $-0.75

PSTV Balance Sheet

Metric Q4'25 Q3'25 Q2'25 Q1'25 Q4'24 Q3'24 Q2'24 Q1'24
Total Assets $16.3M-12.6% $18.7M+80.4% $10.3M-14.2% $12.1M+81.8% $6.6M-4.9% $7.0M-37.8% $11.2M+99.5% $5.6M
Current Assets $15.2M-13.7% $17.6M+90.9% $9.2M-15.2% $10.9M+106.7% $5.3M-2.0% $5.4M-42.8% $9.4M+122.6% $4.2M
Cash & Equivalents $4.3M-68.0% $13.3M+495.1% $2.2M-77.4% $9.9M+12882.9% $76K-93.8% $1.2M-75.1% $4.9M+69.3% $2.9M
Inventory N/A N/A N/A N/A N/A N/A N/A N/A
Accounts Receivable N/A N/A N/A N/A N/A N/A N/A N/A
Goodwill $372K0.0% $372K0.0% $372K0.0% $372K0.0% $372K0.0% $372K0.0% $372K0.0% $372K
Total Liabilities $12.3M-9.5% $13.6M+86.1% $7.3M-79.5% $35.7M+129.1% $15.6M+28.2% $12.2M-35.5% $18.8M+80.1% $10.5M
Current Liabilities $12.3M-9.6% $13.6M+86.1% $7.3M-30.7% $10.6M-32.1% $15.6M+28.4% $12.1M-35.5% $18.8M+80.7% $10.4M
Long-Term Debt N/A N/A N/A N/A N/A N/A N/A N/A
Total Equity $4.0M-20.9% $5.1M+66.6% $3.0M+112.8% -$23.6M-164.2% -$8.9M-73.0% -$5.2M+32.1% -$7.6M-57.6% -$4.8M
Retained Earnings -$515.9M-1.1% -$510.2M-0.9% -$505.7M+1.0% -$510.9M-3.5% -$493.5M-0.8% -$489.6M-0.6% -$486.7M-0.6% -$483.8M

PSTV Cash Flow Statement

Metric Q4'25 Q3'25 Q2'25 Q1'25 Q4'24 Q3'24 Q2'24 Q1'24
Operating Cash Flow -$6.3M-145.6% -$2.5M+56.1% -$5.8M+6.1% -$6.2M-409.7% -$1.2M+67.1% -$3.7M-220.0% -$1.1M+74.5% -$4.5M
Capital Expenditures $30K+11.1% $27K+285.7% $7K+133.3% $3K-72.7% $11K-21.4% $14K-82.7% $81K+102.5% $40K
Free Cash Flow -$6.3M-144.2% -$2.6M+55.6% -$5.8M+6.0% -$6.2M-405.3% -$1.2M+66.9% -$3.7M-200.1% -$1.2M+73.0% -$4.6M
Investing Cash Flow -$1.1M-183.0% $1.3M+128.0% -$4.6M-230.2% $3.6M+5459.4% $64K+811.1% -$9K+99.8% -$3.8M-944.5% -$364K
Financing Cash Flow $2.8M-77.2% $12.3M+340.2% $2.8M-77.5% $12.4M $0 $0-100.0% $7.0M+997.3% -$776K
Dividends Paid N/A N/A N/A N/A N/A N/A N/A N/A
Share Buybacks N/A N/A N/A N/A $0 $0 $0-100.0% $374K

PSTV Financial Ratios

Metric Q4'25 Q3'25 Q2'25 Q1'25 Q4'24 Q3'24 Q2'24 Q1'24
Gross Margin N/A N/A N/A N/A N/A N/A N/A N/A
Operating Margin -420.0%-99.2pp -320.8%-210.2pp -110.7%+223.3pp -333.9%-57.7pp -276.2%-15.3pp -260.9%+28.1pp -289.1%-92.3pp -196.7%
Net Margin -417.9%-101.3pp -316.6%-687.2pp 370.6%+2013.7pp -1643.2%-1366.7pp -276.4%-79.0pp -197.4%+32.5pp -229.9%-35.4pp -194.4%
Return on Equity -143.0%-55.5pp -87.5%-257.3pp 169.8% N/A N/A N/A N/A N/A
Return on Assets -35.0%-11.3pp -23.7%-73.5pp 49.8%+194.1pp -144.3%-85.5pp -58.8%-17.7pp -41.2%-15.0pp -26.2%+31.8pp -58.0%
Current Ratio 1.23-0.1 1.29+0.0 1.26+0.2 1.03+0.7 0.34-0.1 0.44-0.1 0.50+0.1 0.41
Debt-to-Equity 3.09+0.4 2.69+0.3 2.41+3.9 -1.51+0.2 -1.74+0.6 -2.35+0.1 -2.47-0.3 -2.16
FCF Margin -459.9%-275.6pp -184.3%+233.3pp -417.6%+165.5pp -583.1%-496.6pp -86.5%+167.2pp -253.7%-157.5pp -96.3%+175.3pp -271.5%

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Frequently Asked Questions

Plus Therapeutics Inc (PSTV) reported $5.2M in total revenue for fiscal year 2025. This represents a -10.5% change compared to the previous fiscal year. Revenue measures the total income earned from the company's primary business operations before any expenses are deducted.

Plus Therapeutics Inc (PSTV) revenue declined by 10.5% year-over-year, from $5.8M to $5.2M in fiscal year 2025.

No, Plus Therapeutics Inc (PSTV) reported a net income of -$22.4M in fiscal year 2025, with a net profit margin of -429.4%.

Plus Therapeutics Inc (PSTV) reported diluted earnings per share of $-0.29 for fiscal year 2025. EPS represents the portion of a company's net income allocated to each outstanding share of common stock and is widely used to evaluate profitability on a per-share basis.

Plus Therapeutics Inc (PSTV) had EBITDA of -$14.9M in fiscal year 2025, measuring earnings before interest, taxes, depreciation, and amortization.

Plus Therapeutics Inc (PSTV) had an operating margin of -293.5% in fiscal year 2025, reflecting the profitability of core business operations before interest and taxes.

Plus Therapeutics Inc (PSTV) had a net profit margin of -429.4% in fiscal year 2025, representing the share of revenue converted into profit after all expenses.

Plus Therapeutics Inc (PSTV) has a return on equity of -560.2% for fiscal year 2025, measuring how efficiently the company generates profit from shareholder equity.

Plus Therapeutics Inc (PSTV) generated -$20.8M in free cash flow during fiscal year 2025. This represents a -94.8% change compared to the previous fiscal year. Free cash flow represents the cash a company generates after accounting for capital expenditures, and is widely used to assess financial flexibility and shareholder value.

Plus Therapeutics Inc (PSTV) generated -$20.8M in operating cash flow during fiscal year 2025, representing cash generated from core business activities.

Plus Therapeutics Inc (PSTV) had $16.3M in total assets as of fiscal year 2025, including both current and long-term assets.

Plus Therapeutics Inc (PSTV) invested $67K in capital expenditures during fiscal year 2025, funding long-term assets and infrastructure.

Plus Therapeutics Inc (PSTV) invested $8.4M in research and development during fiscal year 2025.

Plus Therapeutics Inc (PSTV) had 139M shares outstanding as of fiscal year 2025.

Plus Therapeutics Inc (PSTV) had a current ratio of 1.23 as of fiscal year 2025, which is considered adequate.

Plus Therapeutics Inc (PSTV) had a debt-to-equity ratio of 3.09 as of fiscal year 2025, measuring the company's financial leverage by comparing total debt to shareholder equity.

Plus Therapeutics Inc (PSTV) had a return on assets of -137.1% for fiscal year 2025, measuring how efficiently the company uses its assets to generate profit.

Based on fiscal year 2025 data, Plus Therapeutics Inc (PSTV) had $4.3M in cash against an annual operating cash burn of $20.8M. This gives an estimated cash runway of approximately 2 months at the current burn rate. Cash runway measures how long a company can continue operating before running out of cash, assuming no additional funding.

Plus Therapeutics Inc (PSTV) has a Piotroski F-Score of 3 out of 9, indicating weak financial health. The F-Score evaluates nine binary signals across profitability (positive ROA, positive cash flow, improving ROA, earnings quality), leverage (decreasing debt, improving liquidity, no share dilution), and operating efficiency (improving gross margin, improving asset turnover). Scores of 7–9 indicate strong and improving fundamentals. Learn more in our complete guide to financial health indicators.

Plus Therapeutics Inc (PSTV) has an earnings quality ratio of 0.93x, considered low quality (accrual-driven). This ratio compares operating cash flow to net income. A ratio above 1.0x means the company generates more cash than its reported earnings, indicating sustainable, cash-backed profits. Ratios below 1.0x suggest earnings rely on accounting accruals rather than actual cash generation. Learn more in our complete guide to financial health indicators.

Plus Therapeutics Inc (PSTV) has an interest coverage ratio of -27.9x, meaning it can struggle to cover its interest obligations. This ratio divides operating income by interest expense. Ratios above 5x indicate strong debt-servicing ability, while ratios below 2x suggest the company may face difficulty meeting interest payments if earnings decline. Learn more in our complete guide to financial health indicators.

Plus Therapeutics Inc (PSTV) scores 12 out of 100 on our Financial Profile, indicating weak overall financial health. This composite score evaluates six dimensions: profitability (operating margin), revenue growth, leverage (debt-to-equity), liquidity (current ratio), cash flow quality (free cash flow margin), and shareholder returns (return on equity). Each dimension is normalized against standard financial benchmarks. Learn more in our complete guide to financial health indicators.

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