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Neurogene Financials

NGNE
Source SEC Filings (10-K/10-Q) Updated Dec 31, 2025 Currency USD FYE December

This page shows Neurogene (NGNE) financial statements, including the income statement, balance sheet, cash flow statement, and key financial ratios. View 14 years of annual fundamentals and quarterly data, with year-over-year growth rates and compound annual growth rates (CAGR). All figures are derived from SEC filings (10-K and 10-Q reports).

Rhea AI NGNE FY2025

Neurogene is running an equity-funded development engine where higher R&D spend translates directly into deeper cash burn.

From FY2023 to FY2025, R&D spending climbed from $44.4M to $75.0M while operating cash burn widened from -$51.4M to -$77.2M, and cash fell to $103.8M despite $307.0M of financing inflows over the same stretch. That combination says new funding has mainly supported a larger development platform rather than creating a durable cash cushion or an operating self-funding loop.

Accounting losses and cash burn are moving together: FY2025 net loss was -$90.4M and operating cash flow was -$77.2M, while capex was only $1.2M. That points to cash use being driven mainly by research and other operating spend, not by heavy fixed-asset investment.

The balance sheet has been rebuilt through financing, not operating improvement: equity moved from -$145.7M in FY2022 to $264.9M in FY2025 while no long-term debt was reported. That matters because today’s losses are being absorbed primarily by shareholder capital rather than by a growing creditor burden.

[ NOT FINANCIAL ADVICE ]

Financial Health Signals

Profitability Growth Leverage Liquidity Cash Flow Returns 33 / 100
Financial Profile 33/100

Based on FY2025 annual data, averaged across the last 3 years for performance metrics (most-recent year weighted highest). How this score is calculated →

Health score ≠ stock price. This rates the quality of Neurogene's business: profitability, growth, balance sheet strength. It doesn't tell you whether the stock is a good buy at today's price. Not financial advice. Use it alongside valuation analysis and your own research.

Leverage
100

Neurogene carries a low D/E ratio of 0.09, meaning only $0.09 of long-term debt for every $1 of shareholders' equity. This conservative leverage earns a score of 100/100, indicating a strong balance sheet with room for future borrowing.

Liquidity
100

With a current ratio of 16.56, Neurogene holds $16.56 in current assets for every $1 of short-term obligations. This comfortable liquidity earns a score of 100/100.

Returns
0

Neurogene generates a -34.1% ROE, indicating limited profit relative to shareholders' investment. This results in a returns score of 0/100. This is down from -24.2% the prior year.

Piotroski F-Score Weak
1/9

Neurogene passes 1 of 9 financial strength tests. 1 of 4 profitability signals pass, no leverage/liquidity signals pass (rising debt, declining liquidity, or share dilution), neither operating efficiency signal passes.

Earnings Quality Low Quality
0.85x

For every $1 of reported earnings, Neurogene generates $0.85 in operating cash flow (-$77.2M OCF vs -$90.4M net income). This low ratio suggests earnings are primarily driven by accounting accruals rather than cash generation, which may not be sustainable.

Interest Coverage At Risk
-20665.6x

Neurogene earns $-20665.6 in operating income for every $1 of interest expense (-$103.3M vs $5K). This narrow margin raises concern about the company's ability to service its debt if operating income declines.

Key Financial Metrics

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Earnings & Revenue

Revenue
$0
YoY-100.0%

Neurogene generated $0 in revenue in fiscal year 2025. This represents a decrease of 100.0% from the prior year.

EBITDA
-$100.3M
YoY-26.3%

Neurogene's EBITDA was -$100.3M in fiscal year 2025, measuring earnings before interest, taxes, depreciation, and amortization. This represents a decrease of 26.3% from the prior year.

Net Income
-$90.4M
YoY-20.2%

Neurogene reported -$90.4M in net income in fiscal year 2025. This represents a decrease of 20.2% from the prior year.

EPS (Diluted)
$-4.24
YoY+0.9%

Neurogene earned $-4.24 per diluted share (EPS) in fiscal year 2025. This represents an increase of 0.9% from the prior year.

Cash & Balance Sheet

Free Cash Flow
-$78.4M
YoY-9.7%

Neurogene generated -$78.4M in free cash flow in fiscal year 2025, representing cash available after capex. This represents a decrease of 9.7% from the prior year.

Cash & Debt
$103.8M
YoY-24.0%
5Y CAGR-11.6%
10Y CAGR+10.1%

Neurogene held $103.8M in cash against $0 in long-term debt as of fiscal year 2025.

Dividends Per Share
N/A
Shares Outstanding
15M
YoY+4.3%
5Y CAGR-18.2%
10Y CAGR-1.0%

Neurogene had 15M shares outstanding in fiscal year 2025. This represents an increase of 4.3% from the prior year.

Margins & Returns

Gross Margin
N/A
Operating Margin
N/A
Net Margin
N/A
Return on Equity
-34.1%
YoY-9.9pp
5Y CAGR-16.7pp
10Y CAGR-14.0pp

Neurogene's ROE was -34.1% in fiscal year 2025, measuring profit generated per dollar of shareholder equity. This is down 9.9 percentage points from the prior year.

Capital Allocation

R&D Spending
$75.0M
YoY+23.1%
5Y CAGR+25.2%
10Y CAGR+16.9%

Neurogene invested $75.0M in research and development in fiscal year 2025. This represents an increase of 23.1% from the prior year.

Share Buybacks
N/A
Capital Expenditures
$1.2M
YoY+46.4%
5Y CAGR-11.8%
10Y CAGR+46.5%

Neurogene invested $1.2M in capex in fiscal year 2025, funding long-term assets and infrastructure. This represents an increase of 46.4% from the prior year.

NGNE Income Statement

Metric Q4'25 Q3'25 Q2'25 Q1'25 Q4'24 Q3'24 Q2'24 Q1'24
Revenue N/A $0 $0 N/A N/A $0-100.0% $925K N/A
Cost of Revenue N/A N/A N/A N/A N/A N/A N/A N/A
Gross Profit N/A N/A N/A N/A N/A N/A N/A N/A
R&D Expenses N/A $17.2M-11.0% $19.4M+9.0% $17.8M N/A $16.3M+3.4% $15.7M+16.3% $13.5M
SG&A Expenses N/A $6.6M-2.4% $6.7M-17.7% $8.2M N/A $5.9M+10.9% $5.3M+1.5% $5.2M
Operating Income N/A -$23.8M+8.8% -$26.1M-0.6% -$25.9M N/A -$22.2M-10.2% -$20.1M-7.2% -$18.8M
Interest Expense N/A $1K0.0% $1K-50.0% $2K N/A $3K-25.0% $4K+33.3% $3K
Income Tax N/A N/A N/A N/A N/A N/A N/A N/A
Net Income N/A -$21.0M+4.8% -$22.0M+2.8% -$22.6M N/A -$20.2M-9.3% -$18.5M-9.3% -$16.9M
EPS (Diluted) N/A $-0.99+5.7% $-1.05+2.8% $-1.08 N/A $-1.19-9.2% $-1.09-9.0% $-1.00

NGNE Balance Sheet

Metric Q4'25 Q3'25 Q2'25 Q1'25 Q4'24 Q3'24 Q2'24 Q1'24
Total Assets $288.6M+0.3% $287.8M-3.2% $297.3M-5.7% $315.3M-6.1% $335.7M+104.6% $164.1M-8.7% $179.8M-7.9% $195.3M
Current Assets $271.8M+0.5% $270.5M-3.0% $279.0M-5.9% $296.4M-6.2% $315.9M+119.9% $143.6M-9.7% $159.1M-8.6% $174.1M
Cash & Equivalents $103.8M+46.3% $71.0M+20.7% $58.8M-16.9% $70.8M-48.2% $136.6M+105.0% $66.6M-40.0% $111.0M-26.0% $150.1M
Inventory N/A N/A N/A N/A N/A N/A N/A N/A
Accounts Receivable N/A N/A N/A N/A N/A N/A N/A N/A
Goodwill N/A N/A N/A N/A N/A N/A N/A N/A
Total Liabilities $23.7M+6.4% $22.3M-7.4% $24.1M+2.4% $23.5M-7.3% $25.4M-5.1% $26.7M+7.6% $24.8M+1.0% $24.6M
Current Liabilities $16.4M+11.6% $14.7M-4.7% $15.4M+9.6% $14.1M-7.0% $15.2M-4.1% $15.8M+20.9% $13.1M+10.6% $11.8M
Long-Term Debt N/A N/A N/A N/A N/A N/A N/A N/A
Total Equity $264.9M-0.2% $265.5M-2.8% $273.3M-6.4% $291.8M-6.0% $310.4M+125.9% $137.4M-11.4% $155.0M-9.2% $170.8M
Retained Earnings -$352.6M-7.5% -$327.9M-6.8% -$307.0M-7.7% -$284.9M-8.6% -$262.3M-8.0% -$242.8M-9.1% -$222.6M-9.1% -$204.1M

NGNE Cash Flow Statement

Metric Q4'25 Q3'25 Q2'25 Q1'25 Q4'24 Q3'24 Q2'24 Q1'24
Operating Cash Flow -$17.4M+10.7% -$19.5M-0.2% -$19.5M+6.3% -$20.8M-18.7% -$17.5M-12.4% -$15.6M+2.1% -$15.9M+26.6% -$21.6M
Capital Expenditures $128K+0.8% $127K-14.2% $148K-81.0% $780K+572.4% $116K-30.5% $167K-63.7% $460K+607.7% $65K
Free Cash Flow -$17.6M+10.6% -$19.6M-0.1% -$19.6M+9.0% -$21.6M-22.4% -$17.6M-12.0% -$15.7M+3.8% -$16.4M+24.7% -$21.7M
Investing Cash Flow $29.6M+34.6% $22.0M+195.2% $7.5M+116.5% -$45.0M+56.1% -$102.6M-254.3% -$29.0M-22.7% -$23.6M-178.9% $29.9M
Financing Cash Flow $20.7M+112.8% $9.7M+17881.5% $54K+1250.0% $4K-100.0% $190.1M+144987.8% $131K-67.2% $399K+106.1% -$6.5M
Dividends Paid N/A N/A N/A N/A N/A N/A N/A N/A
Share Buybacks N/A N/A N/A N/A N/A N/A N/A N/A

NGNE Financial Ratios

Metric Q4'25 Q3'25 Q2'25 Q1'25 Q4'24 Q3'24 Q2'24 Q1'24
Gross Margin N/A N/A N/A N/A N/A N/A N/A N/A
Operating Margin N/A N/A N/A N/A N/A N/A -2176.7% N/A
Net Margin N/A N/A N/A N/A N/A N/A -1999.1% N/A
Return on Equity N/A -7.9%+0.2pp -8.1%-0.3pp -7.8% N/A -14.7%-2.8pp -11.9%-2.0pp -9.9%
Return on Assets N/A -7.3%+0.1pp -7.4%-0.2pp -7.2% N/A -12.3%-2.0pp -10.3%-1.6pp -8.7%
Current Ratio 16.56-1.8 18.39+0.3 18.07-3.0 21.03+0.2 20.84+11.8 9.09-3.1 12.17-2.6 14.74
Debt-to-Equity 0.090.0 0.080.0 0.090.0 0.080.0 0.08-0.1 0.19+0.0 0.16+0.0 0.14
FCF Margin N/A N/A N/A N/A N/A N/A -1767.9% N/A

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Frequently Asked Questions

Neurogene (NGNE) reported $0 in total revenue for fiscal year 2025. This represents a -100.0% change compared to the previous fiscal year. Revenue measures the total income earned from the company's primary business operations before any expenses are deducted.

Neurogene (NGNE) revenue declined by 100% year-over-year, from $925K to $0 in fiscal year 2025.

No, Neurogene (NGNE) reported a net income of -$90.4M in fiscal year 2025.

Neurogene (NGNE) reported diluted earnings per share of $-4.24 for fiscal year 2025. This represents a 0.9% change compared to the previous fiscal year. EPS represents the portion of a company's net income allocated to each outstanding share of common stock and is widely used to evaluate profitability on a per-share basis.

Neurogene (NGNE) had EBITDA of -$100.3M in fiscal year 2025, measuring earnings before interest, taxes, depreciation, and amortization.

Neurogene (NGNE) has a return on equity of -34.1% for fiscal year 2025, measuring how efficiently the company generates profit from shareholder equity.

Neurogene (NGNE) generated -$78.4M in free cash flow during fiscal year 2025. This represents a -9.7% change compared to the previous fiscal year. Free cash flow represents the cash a company generates after accounting for capital expenditures, and is widely used to assess financial flexibility and shareholder value.

Neurogene (NGNE) generated -$77.2M in operating cash flow during fiscal year 2025, representing cash generated from core business activities.

Neurogene (NGNE) had $288.6M in total assets as of fiscal year 2025, including both current and long-term assets.

Neurogene (NGNE) invested $1.2M in capital expenditures during fiscal year 2025, funding long-term assets and infrastructure.

Neurogene (NGNE) invested $75.0M in research and development during fiscal year 2025.

Neurogene (NGNE) had 15M shares outstanding as of fiscal year 2025.

Neurogene (NGNE) had a current ratio of 16.56 as of fiscal year 2025, which is generally considered healthy.

Neurogene (NGNE) had a debt-to-equity ratio of 0.09 as of fiscal year 2025, measuring the company's financial leverage by comparing total debt to shareholder equity.

Neurogene (NGNE) had a return on assets of -31.3% for fiscal year 2025, measuring how efficiently the company uses its assets to generate profit.

Based on fiscal year 2025 data, Neurogene (NGNE) had $103.8M in cash against an annual operating cash burn of $77.2M. This gives an estimated cash runway of approximately 16 months at the current burn rate. Cash runway measures how long a company can continue operating before running out of cash, assuming no additional funding.

Neurogene (NGNE) has a Piotroski F-Score of 1 out of 9, indicating weak financial health. The F-Score evaluates nine binary signals across profitability (positive ROA, positive cash flow, improving ROA, earnings quality), leverage (decreasing debt, improving liquidity, no share dilution), and operating efficiency (improving gross margin, improving asset turnover). Scores of 7 to 9 indicate strong and improving fundamentals. Learn more in our complete guide to financial health indicators.

Neurogene (NGNE) has an earnings quality ratio of 0.85x, considered low quality (accrual-driven). This ratio compares operating cash flow to net income. A ratio above 1.0x means the company generates more cash than its reported earnings, indicating sustainable, cash-backed profits. Ratios below 1.0x suggest earnings rely on accounting accruals rather than actual cash generation. Learn more in our complete guide to financial health indicators.

Neurogene (NGNE) has an interest coverage ratio of -20665.6x, meaning it can struggle to cover its interest obligations. This ratio divides operating income by interest expense. Ratios above 5x indicate strong debt-servicing ability, while ratios below 2x suggest the company may face difficulty meeting interest payments if earnings decline. Learn more in our complete guide to financial health indicators.

Neurogene (NGNE) scores 33 out of 100 on our Financial Profile, indicating weak overall financial health. This composite score evaluates six dimensions: profitability (operating margin), revenue growth, leverage (debt-to-equity), liquidity (current ratio), cash flow quality (free cash flow margin), and shareholder returns (return on equity). Each dimension is normalized against standard financial benchmarks. Learn more in our complete guide to financial health indicators.

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