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Arrowhead Pharma Financials

ARWR
Source SEC Filings (10-K/10-Q) Updated Mar 31, 2026 Currency USD FYE September

This page shows Arrowhead Pharma (ARWR) financial statements, including the income statement, balance sheet, cash flow statement, and key financial ratios. View 16 years of annual fundamentals and quarterly data, with year-over-year growth rates and compound annual growth rates (CAGR). All figures are derived from SEC filings (10-K and 10-Q reports).

Rhea AI ARWR FY2025

Arrowhead’s event-driven revenue sits on a large recurring R&D base, so reported earnings can swing far faster than underlying spending.

Cash conversion improved alongside operations: operating cash flow swung to $179.6M from -$462.9M in FY2024. Net income did not follow, staying at -$1.6M because interest expense reached $89.4M, so financing costs absorbed much of the operating rebound even as the core business stopped consuming cash.

The jump to positive free cash flow was also a capital intensity shift: capital spending fell to $22.7M from $141.5M in FY2024. That makes FY2024 look more like a build year than a normal cash-burn baseline, and it means FY2025 cash generation came from lighter reinvestment as well as better operations.

Near-term liquidity looks comfortable with a current ratio of 4.9x and cash of $226.5M. But the company remains balance-sheet dependent: liabilities of $919.2M still exceed equity of $466.1M, so the recovery has not yet returned the business to a fully self-funded posture.

[ NOT FINANCIAL ADVICE ]

Financial Health Signals

Profitability Growth Leverage Liquidity Cash Flow Returns 43 / 100
Financial Profile 43/100

Based on FY2025 annual data, averaged across the last 3 years for performance metrics (most-recent year weighted highest). How this score is calculated →

Health score ≠ stock price. This rates the quality of Arrowhead Pharma's business: profitability, growth, balance sheet strength. It doesn't tell you whether the stock is a good buy at today's price. Not financial advice. Use it alongside valuation analysis and your own research.

Profitability
0

Arrowhead Pharma has an operating margin of 11.9%, meaning the company retains $12 of operating profit per $100 of revenue. This below-average margin results in a low score of 0/100, suggesting thin profitability after operating expenses. This is up from -16927.1% the prior year.

Growth
100

Arrowhead Pharma's revenue surged 23258.2% year-over-year to $829.4M, reflecting rapid business expansion. This strong growth earns a score of 100/100.

Leverage
62

Arrowhead Pharma has a moderate D/E ratio of 1.97. This balance of debt and equity financing earns a leverage score of 62/100.

Liquidity
97

With a current ratio of 4.86, Arrowhead Pharma holds $4.86 in current assets for every $1 of short-term obligations. This comfortable liquidity earns a score of 97/100.

Cash Flow
0

Arrowhead Pharma's free cash flow margin of 18.9% results in a low score of 0/100. Capital expenditures of $22.7M absorb a large share of operating cash flow.

Returns
0

Arrowhead Pharma generates a -0.4% ROE, indicating limited profit relative to shareholders' investment. This results in a returns score of 0/100. This is up from -323.3% the prior year.

Altman Z-Score Safe
6.97

Arrowhead Pharma scores 6.97, well above the 2.99 safe threshold. The score is driven primarily by a large market capitalization ($10.9B) relative to total liabilities ($919.2M). This indicates low bankruptcy risk based on profitability, leverage, and asset efficiency.

Piotroski F-Score Neutral
4/9

Arrowhead Pharma passes 4 of 9 financial strength tests. 3 of 4 profitability signals pass, no leverage/liquidity signals pass (rising debt, declining liquidity, or share dilution), both operating efficiency signals pass.

Earnings Quality Mixed
-110.09x

For every $1 of reported earnings, Arrowhead Pharma generates $-110.09 in operating cash flow ($179.6M OCF vs -$1.6M net income). This mixed ratio suggests some earnings may rely on non-cash accounting items.

Interest Coverage At Risk
1.1x

Arrowhead Pharma earns $1.1 in operating income for every $1 of interest expense ($98.3M vs $89.4M). This narrow margin raises concern about the company's ability to service its debt if operating income declines.

Key Financial Metrics

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Earnings & Revenue

Revenue
$829.4M
YoY+23258.2%
5Y CAGR+56.6%
10Y CAGR+115.6%

Arrowhead Pharma generated $829.4M in revenue in fiscal year 2025. This represents an increase of 23258.2% from the prior year.

EBITDA
$120.5M
YoY+120.6%

Arrowhead Pharma's EBITDA was $120.5M in fiscal year 2025, measuring earnings before interest, taxes, depreciation, and amortization. This represents an increase of 120.6% from the prior year.

Net Income
-$1.6M
YoY+99.7%

Arrowhead Pharma reported -$1.6M in net income in fiscal year 2025. This represents an increase of 99.7% from the prior year.

EPS (Diluted)
$-0.01
YoY+99.8%

Arrowhead Pharma earned $-0.01 per diluted share (EPS) in fiscal year 2025. This represents an increase of 99.8% from the prior year.

Cash & Balance Sheet

Free Cash Flow
$156.9M
YoY+126.0%

Arrowhead Pharma generated $156.9M in free cash flow in fiscal year 2025, representing cash available after capex. This represents an increase of 126.0% from the prior year.

Cash & Debt
$226.5M
YoY+120.6%
5Y CAGR+9.5%
10Y CAGR+10.8%

Arrowhead Pharma held $226.5M in cash against $0 in long-term debt as of fiscal year 2025.

Dividends Per Share
N/A
Shares Outstanding
136M
YoY+9.1%
5Y CAGR+5.8%
10Y CAGR+8.6%

Arrowhead Pharma had 136M shares outstanding in fiscal year 2025. This represents an increase of 9.1% from the prior year.

Margins & Returns

Gross Margin
N/A
Operating Margin
11.9%
YoY+16938.9pp
5Y CAGR+117.7pp
10Y CAGR+25135.9pp

Arrowhead Pharma's operating margin was 11.9% in fiscal year 2025, reflecting core business profitability. This is up 16938.9 percentage points from the prior year.

Net Margin
-0.2%
YoY+16882.2pp
5Y CAGR+95.9pp
10Y CAGR+24068.1pp

Arrowhead Pharma's net profit margin was -0.2% in fiscal year 2025, showing the share of revenue converted to profit. This is up 16882.2 percentage points from the prior year.

Return on Equity
-0.4%
YoY+322.9pp
5Y CAGR+18.0pp
10Y CAGR+83.1pp

Arrowhead Pharma's ROE was -0.4% in fiscal year 2025, measuring profit generated per dollar of shareholder equity. This is up 322.9 percentage points from the prior year.

Capital Allocation

R&D Spending
$607.2M
YoY+20.0%
5Y CAGR+36.3%
10Y CAGR+29.1%

Arrowhead Pharma invested $607.2M in research and development in fiscal year 2025. This represents an increase of 20.0% from the prior year.

Share Buybacks
N/A
Capital Expenditures
$22.7M
YoY-84.0%
5Y CAGR+13.7%
10Y CAGR+27.7%

Arrowhead Pharma invested $22.7M in capex in fiscal year 2025, funding long-term assets and infrastructure. This represents a decrease of 84.0% from the prior year.

ARWR Income Statement

Metric Q2'26 Q1'26 Q4'25 Q3'25 Q2'25 Q1'25 Q4'24 Q3'24
Revenue $73.7M-72.1% $264.0M+2.9% $256.5M+823.7% $27.8M-94.9% $542.7M+21608.4% $2.5M N/A $0
Cost of Revenue N/A N/A N/A N/A N/A N/A N/A N/A
Gross Profit N/A N/A N/A N/A N/A N/A N/A N/A
R&D Expenses $173.3M-2.2% $177.2M+1.4% $174.7M+7.6% $162.4M+22.0% $133.1M-2.8% $137.0M N/A $152.4M
SG&A Expenses $41.7M-9.3% $46.0M+22.1% $37.7M+21.7% $30.9M+9.0% $28.4M+5.6% $26.9M N/A $23.7M
Operating Income -$141.3M-446.1% $40.8M-7.5% $44.1M+126.6% -$165.6M-143.4% $381.2M+336.2% -$161.4M N/A -$176.1M
Interest Expense $23.8M+6.0% $22.5M+3.7% $21.7M-11.0% $24.4M+12.7% $21.6M0.0% $21.6M N/A $5.1M
Income Tax $7K-75.9% $29K-99.9% $20.0M+4676.7% -$437K-124.9% $1.8M+1601.9% $103K N/A $0
Net Income -$132.7M-530.8% $30.8M+229.7% -$23.8M+86.4% -$175.2M-147.3% $370.4M+314.0% -$173.1M N/A -$170.8M
EPS (Diluted) $-0.93-522.7% $0.22 N/A $-1.26-145.8% $2.75+297.8% $-1.39 N/A $-1.38

ARWR Balance Sheet

Metric Q2'26 Q1'26 Q4'25 Q3'25 Q2'25 Q1'25 Q4'24 Q3'24
Total Assets $2.3B+41.4% $1.6B+15.8% $1.4B+0.3% $1.4B-12.3% $1.6B+55.2% $1.0B-11.1% $1.1B+29.0% $883.8M
Current Assets $1.8B+56.7% $1.2B+23.5% $950.6M+0.4% $946.9M-16.6% $1.1B+99.0% $570.5M-18.0% $695.5M+54.5% $450.1M
Cash & Equivalents $188.5M-6.5% $201.6M-11.0% $226.5M+74.5% $129.8M-30.1% $185.7M+244.6% $53.9M-47.5% $102.7M+48.0% $69.4M
Inventory N/A N/A N/A N/A N/A N/A N/A N/A
Accounts Receivable $15.7M-92.8% $218.9M+3107.4% $6.8M-29.6% $9.7M+310.1% $2.4M-5.4% $2.5M $0 $0
Goodwill N/A N/A N/A N/A N/A N/A N/A N/A
Total Liabilities $1.7B+59.7% $1.0B+12.7% $919.2M+7.1% $858.3M-3.6% $890.2M-7.4% $961.1M+0.7% $954.4M+72.5% $553.2M
Current Liabilities $295.2M-15.0% $347.4M+77.7% $195.5M+0.5% $194.5M-11.8% $220.5M+135.2% $93.8M-9.1% $103.2M+6.7% $96.7M
Long-Term Debt $159.6M N/A N/A N/A N/A N/A N/A N/A
Total Equity $614.0M+8.0% $568.4M+22.0% $466.1M-10.8% $522.3M-23.6% $683.3M+1199.4% $52.6M-71.6% $185.4M-43.9% $330.5M
Retained Earnings -$1.7B-8.3% -$1.6B+1.9% -$1.6B-1.5% -$1.6B-12.3% -$1.4B+20.6% -$1.8B-10.6% -$1.6B-11.7% -$1.5B

ARWR Cash Flow Statement

Metric Q2'26 Q1'26 Q4'25 Q3'25 Q2'25 Q1'25 Q4'24 Q3'24
Operating Cash Flow $84.4M+526.4% $13.5M-34.2% $20.5M+113.2% -$154.7M-133.6% $460.1M+414.5% -$146.3M-6.6% -$137.2M-18.9% -$115.4M
Capital Expenditures $2.6M+19.4% $2.1M-71.3% $7.5M+216.8% $2.4M-55.4% $5.3M-29.5% $7.5M-69.1% $24.3M+68.1% $14.4M
Free Cash Flow $81.9M+622.5% $11.3M-12.8% $13.0M+108.3% -$157.1M-134.5% $454.8M+395.7% -$153.8M+4.8% -$161.5M-24.4% -$129.9M
Investing Cash Flow -$894.3M-3666.7% -$23.7M-132.7% $72.6M-48.6% $141.4M+133.6% -$420.2M-646.4% $76.9M+134.5% -$222.9M-3308.0% $6.9M
Financing Cash Flow $795.7M+5494.7% -$14.8M-502.0% $3.7M+108.6% -$42.7M-146.2% $92.4M+347.7% $20.6M-94.7% $389.1M+672.2% $50.4M
Dividends Paid N/A N/A N/A N/A N/A N/A N/A N/A
Share Buybacks N/A N/A N/A N/A N/A N/A N/A N/A

ARWR Financial Ratios

Metric Q2'26 Q1'26 Q4'25 Q3'25 Q2'25 Q1'25 Q4'24 Q3'24
Gross Margin N/A N/A N/A N/A N/A N/A N/A N/A
Operating Margin -191.6%-207.0pp 15.5%-1.7pp 17.2%+613.4pp -596.2%-666.5pp 70.2%+6526.7pp -6456.5% N/A N/A
Net Margin -180.0%-191.7pp 11.7%+20.9pp -9.3%+621.9pp -631.1%-699.4pp 68.3%+6991.7pp -6923.4% N/A N/A
Return on Equity -21.6%-27.0pp 5.4%+10.5pp -5.1%+28.5pp -33.6%-87.8pp 54.2%+383.3pp -329.1% N/A -51.7%
Return on Assets -5.9%-7.8pp 1.9%+3.6pp -1.7%+11.0pp -12.7%-36.2pp 23.5%+40.6pp -17.1% N/A -19.3%
Current Ratio 6.23+2.9 3.38-1.5 4.860.0 4.87-0.3 5.15-0.9 6.09-0.7 6.74+2.1 4.65
Debt-to-Equity 2.69+0.9 1.82-0.2 1.97+0.3 1.64+0.3 1.30-17.0 18.28+13.1 5.15+3.5 1.67
FCF Margin 111.0%+106.8pp 4.3%-0.8pp 5.1%+570.8pp -565.7%-649.5pp 83.8%+6235.3pp -6151.5% N/A N/A

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Frequently Asked Questions

Arrowhead Pharma (ARWR) reported $829.4M in total revenue for fiscal year 2025. This represents a 23258.2% change compared to the previous fiscal year. Revenue measures the total income earned from the company's primary business operations before any expenses are deducted.

Arrowhead Pharma (ARWR) revenue grew by 23258.2% year-over-year, from $3.6M to $829.4M in fiscal year 2025.

No, Arrowhead Pharma (ARWR) reported a net income of -$1.6M in fiscal year 2025, with a net profit margin of -0.2%.

Arrowhead Pharma (ARWR) reported diluted earnings per share of $-0.01 for fiscal year 2025. This represents a 99.8% change compared to the previous fiscal year. EPS represents the portion of a company's net income allocated to each outstanding share of common stock and is widely used to evaluate profitability on a per-share basis.

Arrowhead Pharma (ARWR) had EBITDA of $120.5M in fiscal year 2025, measuring earnings before interest, taxes, depreciation, and amortization.

Arrowhead Pharma (ARWR) had an operating margin of 11.9% in fiscal year 2025, reflecting the profitability of core business operations before interest and taxes.

Arrowhead Pharma (ARWR) had a net profit margin of -0.2% in fiscal year 2025, representing the share of revenue converted into profit after all expenses.

Arrowhead Pharma (ARWR) has a return on equity of -0.4% for fiscal year 2025, measuring how efficiently the company generates profit from shareholder equity.

Arrowhead Pharma (ARWR) generated $156.9M in free cash flow during fiscal year 2025. This represents a 126.0% change compared to the previous fiscal year. Free cash flow represents the cash a company generates after accounting for capital expenditures, and is widely used to assess financial flexibility and shareholder value.

Arrowhead Pharma (ARWR) generated $179.6M in operating cash flow during fiscal year 2025, representing cash generated from core business activities.

Arrowhead Pharma (ARWR) had $1.4B in total assets as of fiscal year 2025, including both current and long-term assets.

Arrowhead Pharma (ARWR) invested $22.7M in capital expenditures during fiscal year 2025, funding long-term assets and infrastructure.

Arrowhead Pharma (ARWR) invested $607.2M in research and development during fiscal year 2025.

Arrowhead Pharma (ARWR) had 136M shares outstanding as of fiscal year 2025.

Arrowhead Pharma (ARWR) had a current ratio of 4.86 as of fiscal year 2025, which is generally considered healthy.

Arrowhead Pharma (ARWR) had a debt-to-equity ratio of 1.97 as of fiscal year 2025, measuring the company's financial leverage by comparing total debt to shareholder equity.

Arrowhead Pharma (ARWR) had a return on assets of -0.1% for fiscal year 2025, measuring how efficiently the company uses its assets to generate profit.

Arrowhead Pharma (ARWR) has an Altman Z-Score of 6.97, placing it in the Safe Zone (low bankruptcy risk). The Z-Score combines five financial ratios (working capital, retained earnings, EBIT, market capitalization, and revenue relative to total assets) to predict the likelihood of bankruptcy. Scores above 2.99 indicate financial safety while scores below 1.81 suggest financial distress. Learn more in our complete guide to financial health indicators.

Arrowhead Pharma (ARWR) has a Piotroski F-Score of 4 out of 9, indicating neutral financial health. The F-Score evaluates nine binary signals across profitability (positive ROA, positive cash flow, improving ROA, earnings quality), leverage (decreasing debt, improving liquidity, no share dilution), and operating efficiency (improving gross margin, improving asset turnover). Scores of 7 to 9 indicate strong and improving fundamentals. Learn more in our complete guide to financial health indicators.

Arrowhead Pharma (ARWR) has an earnings quality ratio of -110.09x, considered mixed quality. This ratio compares operating cash flow to net income. A ratio above 1.0x means the company generates more cash than its reported earnings, indicating sustainable, cash-backed profits. Ratios below 1.0x suggest earnings rely on accounting accruals rather than actual cash generation. Learn more in our complete guide to financial health indicators.

Arrowhead Pharma (ARWR) has an interest coverage ratio of 1.1x, meaning it can struggle to cover its interest obligations. This ratio divides operating income by interest expense. Ratios above 5x indicate strong debt-servicing ability, while ratios below 2x suggest the company may face difficulty meeting interest payments if earnings decline. Learn more in our complete guide to financial health indicators.

Arrowhead Pharma (ARWR) scores 43 out of 100 on our Financial Profile, indicating moderate overall financial health. This composite score evaluates six dimensions: profitability (operating margin), revenue growth, leverage (debt-to-equity), liquidity (current ratio), cash flow quality (free cash flow margin), and shareholder returns (return on equity). Each dimension is normalized against standard financial benchmarks. Learn more in our complete guide to financial health indicators.

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