[Form 4] Vor Biopharma Inc. Insider Trading Activity

Rhea-AI Filing Summary

Vor Biopharma Inc. (VOR) insiders reported multiple open-market sales of common stock on 10/08/2025 and 10/09/2025. The filings show four sale transactions totaling 124,146 shares disposed at weighted-average prices ranging from $31.9181 to $34.3391. After these transactions, the reported beneficial ownership held by Reprogrammed Interchange LLC and attributed to Reid Hoffman fell to 1,374,775 shares (direct/indirect holdings by Reprogrammed). The Form 4 includes explanations that the reported prices are weighted averages from multiple trades and offers to provide trade-level detail on request. The document is signed by Reid Hoffman and Frank Huang on 10/10/2025.

Positive

• Full Form 4 disclosure filed and signed, providing weighted-average prices and offering trade-level detail on request
• Clear attribution of holdings to Reprogrammed Interchange LLC and explanation of Reid Hoffman’s indirect pecuniary interest

Negative

• Material insider selling: total of 124,146 shares sold across four transactions on 10/08/2025–10/09/2025
• Reduced beneficial holdings reported for Reprogrammed Interchange LLC to 1,374,775 shares following the sales

Insights

Corporate Governance / Insider Trading Expert

TL;DR: Significant open-market sales by an affiliated investor reduced holdings; disclosure is explicit with weighted-average pricing.

The filings report four separate sale events on 10/08/2025 and 10/09/2025 totaling 124,146 shares sold at weighted-average prices between $31.9181 and $34.3391. The reporting structure shows sales executed by Reprogrammed Interchange LLC and by an individual reporting person, with beneficial ownership attributed to Reprogrammed at 1,374,775 shares after the transactions.

Risk dependencies include market impact and timing: these are open-market dispositions (transaction code S), and the filings disclose only weighted-average prices while offering to provide per-trade detail on request. Monitor subsequent Forms 4 for additional disposals or changes in beneficial ownership in the near term (weeks to months) to assess ongoing insider positioning.

SEC Form 4

FORM 4

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940

OMB APPROVAL

OMB Number:			3235-0287
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hours per response:			0.5

Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.

1. Name and Address of Reporting Person^*

Reprogrammed Interchange LLC

(Last) (First) (Middle)

101 MISSION STREET, SUITE 1000

(Street)

SAN FRANCISCO CA 94105

(City) (State) (Zip)

2. Issuer Name and Ticker or Trading Symbol
Vor Biopharma Inc. [ VOR ]

5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)

	Director	X	10% Owner
	Officer (give title below)		Other (specify below)

3. Date of Earliest Transaction (Month/Day/Year)
10/08/2025

4. If Amendment, Date of Original Filed (Month/Day/Year)

6. Individual or Joint/Group Filing (Check Applicable Line)

	Form filed by One Reporting Person
X	Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	3. Transaction Code (Instr. 8)		4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
			Code	V	Amount	(A) or (D)	Price
Common Stock	10/08/2025		S		60,926	D	$33.7536(1)	1,437,995(2)	D
Common Stock	10/08/2025		S		14,336	D	$34.3391(3)	1,423,659(2)	D
Common Stock	10/09/2025		S		33,842	D	$31.9181(4)	1,389,817(2)	D
Common Stock	10/09/2025		S		15,042	D	$32.4052(5)	1,374,775(2)	D

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
				Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares

1. Name and Address of Reporting Person^*

Reprogrammed Interchange LLC

(Last) (First) (Middle)

101 MISSION STREET, SUITE 1000

(Street)

SAN FRANCISCO CA 94105

(City) (State) (Zip)

Relationship of Reporting Person(s) to Issuer

	Director	X	10% Owner
	Officer (give title below)		Other (specify below)

1. Name and Address of Reporting Person^*

Hoffman Reid

(Last) (First) (Middle)

101 MISSION STREET, SUITE 1000

(Street)

SAN FRANCISCO CA 94105

(City) (State) (Zip)

Relationship of Reporting Person(s) to Issuer

	Director	X	10% Owner
	Officer (give title below)		Other (specify below)

Explanation of Responses:

1. This transaction was executed in multiple trades at prices ranging from $33.20 to $34.19. The price reported above reflects the weighted average sale price. The Reporting Person undertakes to provide upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate sale price.

2. The securities are held by Reprogrammed Interchange LLC ("Reprogrammed"). Reid Hoffman may be deemed a beneficial owner of securities held by Reprogrammed by virtue of his shared control over and indirect pecuniary interest in Reprogrammed. Mr. Hoffman disclaims beneficial ownership of the securities held by Reprogrammed, except to the extent of his pecuniary interest therein.

3. This transaction was executed in multiple trades at prices ranging from $34.20 to $34.53. The price reported above reflects the weighted average sale price. The Reporting Person undertakes to provide upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate sale price.

4. This transaction was executed in multiple trades at prices ranging from $31.26 to $32.25. The price reported above reflects the weighted average sale price. The Reporting Person undertakes to provide upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate sale price.

5. This transaction was executed in multiple trades at prices ranging from $32.26 to $32.855. The price reported above reflects the weighted average sale price. The Reporting Person undertakes to provide upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate sale price.

	/s/ Reid Hoffman	10/10/2025
	/s/ Frank Huang, Manager of Reprogrammed Interchange LLC	10/10/2025
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
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FAQ

What insider transactions were reported for Vor Biopharma (VOR)?

Insiders reported four open-market sales totaling 124,146 shares on 10/08/2025 and 10/09/2025.

At what prices were the VOR shares sold?

The Form 4 reports weighted-average sale prices ranging from $31.9181 to $34.3391; per-trade details are available on request per the filing.

Who conducted the sales listed on the Form 4?

Sales were reported by Reprogrammed Interchange LLC and Reid Hoffman is named as a reporting person with indirect pecuniary interest in Reprogrammed.

How many VOR shares remain beneficially owned after the reported transactions?

The filing reports 1,374,775 shares beneficially owned following the reported transactions.

When was the Form 4 signed?

The Form 4 is signed by Reid Hoffman and Frank Huang, Manager of Reprogrammed Interchange LLC, on 10/10/2025.