Welcome to our dedicated page for Tango Therapeutics news (Ticker: TNGX), a resource for investors and traders seeking the latest updates and insights on Tango Therapeutics stock.
Tango Therapeutics, Inc. (NASDAQ: TNGX) is a pioneering biotechnology company focused on discovering and developing novel medicines aimed at targeting cancer vulnerabilities. Founded in 2017 with an initial $55 million Series A investment from Third Rock Ventures, Tango leverages the latest advancements in DNA sequencing and CRISPR-based target discovery. Their goal is to create breakthrough medicines that offer deeper and more sustained benefits than current targeted therapies and to extend the effectiveness of available immuno-oncology agents.
Tango Therapeutics concentrates on three core areas of drug development, each addressing well-defined patient populations with limited treatment options. These areas include:
- Loss of tumor suppressor gene function
- Multiple oncogenic drivers
- Immune evasion
The company’s robust product pipeline includes several promising candidates:
- TNG908 - An MTA-cooperative inhibitor of PRMT5 designed to selectively target cancer cells with MTAP deletions.
- TNG462 - Another advanced preclinical candidate aimed at targeting different cancer types.
- TNG348 - Recently entered Phase 1/2 clinical trials for advanced ovarian, breast, and other cancers with DNA damage repair pathway defects.
- Other discovery programs such as TNG260 and TNG348, focusing on different cancer types with limited current treatment options.
In recent developments, Tango announced dosing the first patient in the TNG348 Phase 1/2 trial, a significant milestone for the company. The trial will assess the safety, pharmacokinetics, pharmacodynamics, and efficacy of TNG348 both as a single agent and in combination with olaparib, a PARP inhibitor.
Tango has established partnerships with several key players in the pharmaceutical industry. These collaborations have significantly bolstered their drug development pipeline. However, recent news highlights the termination of the TNG348 Phase 1/2 clinical trial due to observed toxicity, underscoring the inherent risks in drug development.
For more information, visit www.tangotx.com.
Tango Therapeutics (TNGX) announced significant advancements in cancer treatments, including the start of a Phase 1/2 trial for TNG908, a PRMT5 inhibitor, now open for enrollment targeting MTAP-deleted tumors. The company also declared TNG462 and TNG260 as development candidates for similar applications. With a robust cash position of $450 million, Tango aims to progress its pipeline into late 2024. Financially, Tango reported a net loss of $25.2 million for Q1 2022, with research and development expenses rising to $24.3 million compared to $15 million a year prior.
Tango Therapeutics (NASDAQ: TNGX) announced its management team will participate in a fireside chat at Guggenheim Synthetic Lethality Day 2022 on May 16 at 10:00 AM ET. The event will be accessible via a live webcast found on the company's website under the 'Events & Presentations' section. Additionally, a replay will be available for 30 days post-event. The company focuses on developing precision cancer medicines by leveraging synthetic lethality, targeting tumor suppressor gene loss, and enhancing cancer treatments.
Tango Therapeutics (TNGX) announced significant developments, including the Fast Track Designation for its lead candidate, TNG908, an inhibitor targeting MTAP-deleted cancers. The company plans to start a Phase 1/2 clinical trial in Q2 2022, with preliminary data expected in H1 2023. Tango also reported financial results for 2021, revealing a net loss of $58.2 million and a revenue of $37 million. A strong cash position of $485 million is anticipated to support operations through the second half of 2024.
Tango Therapeutics (NASDAQ: TNGX) announced three abstracts selected for presentation at the AACR 2022 Annual Meeting, highlighting innovative cancer therapies. The presentations will cover:
- TNG908: an MTAP-null selective PRMT5 inhibitor showing tumor regressions in various cancer models.
- USP1 inhibitor: exploring synthetic lethality in BRCA1-mutant cancer via PCNA ubiquitination.
- UMIBB: introducing a Bayesian method enhancing CRISPR-Cas9 screen analysis.
These advancements aim to strengthen precision oncology and enrich Tango's therapeutic pipeline.
Tango Therapeutics, Inc. (NASDAQ: TNGX) announced the presentation of an e-Poster at the 2022 ESMO Targeted Anticancer Therapies Congress, scheduled for March 7-8, 2022. The poster titled 'Evidence for synergy between TNG908, an MTAP-null selective PRMT5 inhibitor, and sotorasib in an MTAP-null/KRASG12C xenograft model' will be presented on March 4 at 12:00 CET. Tango focuses on developing precision cancer medicines based on synthetic lethality, targeting crucial cancer pathways.
Tango Therapeutics (NASDAQ: TNGX) has announced participation in two virtual investor conferences in February 2022. The Guggenheim 2022 Oncology Conference is scheduled for February 9 at 9:00 AM ET, followed by the 11th Annual SVB Leerink Global Healthcare Conference on February 16 at 1:00 PM ET. Live webcasts of these events will be available on the company's website, with replays accessible for 30 days post-event. Tango specializes in precision cancer medicines, employing innovative approaches to target cancer effectively.
Tango Therapeutics, a biotechnology company focused on precision cancer medicines, announced participation in two virtual investor conferences in February 2022. The Guggenheim 2022 Oncology Conference is scheduled for February 9, 2022, at 9:00 AM ET, while the 11th Annual SVB Leerink Global Healthcare Conference will take place on February 16, 2022, at 1:00 PM ET. Live webcasts will be available under the 'Events & Presentations' section on the company’s website, with replays accessible for 30 days.
Tango Therapeutics, Inc. (NASDAQ: TNGX) announced the FDA's clearance of the IND for its lead program, TNG908, a selective PRMT5 inhibitor targeting cancers with MTAP deletions. The first-in-human clinical trial is expected to commence in 1H 2022, with preliminary data anticipated in 1H 2023. The company is also advancing its Target 3 program, aimed at reversing immune evasion in STK11 mutant cancers, and plans to develop a USP1 inhibitor for BRCA1-mutant cancers in 2H 2022. Tango’s cash balance is projected to fund operations into 2H 2024.
Tango Therapeutics (NASDAQ: TNGX) announced participation in the Jefferies London Healthcare Conference on November 18, 2021. The management team will present, with the session available on-demand starting at 8 AM GMT. A replay will be accessible for 30 days on the company's website. Tango focuses on precision cancer medicine, leveraging synthetic lethality to target cancer cells and enhance treatment efficacy. For more details, visit tangotx.com.
Tango Therapeutics (TNGX) reported a strong cash position of $504 million, ensuring funding for operations through 2024. The company is on track for an IND filing for TNG908, a PRMT5 inhibitor targeting cancers with MTAP deletion, expected in Q4 2021. Q3 2021 collaboration revenue rose to $6.8 million, a significant turnaround from a prior decline. R&D expenses increased to $21.9 million, while the net loss decreased to $19.6 million or $0.28 per share, down from $26.8 million previously.
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