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SQZ Biotechnologies, spun out of MIT, is at the forefront of developing next-generation cell therapies. The company leverages its proprietary technology to harness the power of patients' immune systems to combat various diseases. SQZ Biotechnologies aims to empower cells to change lives through innovative scientific advancements.

The core business of SQZ focuses on creating groundbreaking treatments that target a wide range of medical conditions. By altering immune cells to enhance their disease-fighting capabilities, the company seeks to make significant strides in the field of immunotherapy. Their cutting-edge technology allows for precise modification of cells, paving the way for more effective and personalized treatments.

Recently, SQZ Biotechnologies has made substantial progress in its research and development efforts. Key achievements include successful preclinical trials and the initiation of various clinical programs. These programs aim to address challenging conditions like cancer and autoimmune diseases, offering new hope to patients worldwide.

Current projects at SQZ involve a robust pipeline of therapies that are in different stages of development. The company is also engaged in strategic partnerships with leading pharmaceutical companies and academic institutions. These collaborations are crucial in accelerating the development and commercialization of their innovative therapies.

Financially, SQZ Biotechnologies remains committed to driving growth and value for its shareholders. With a solid balance sheet and strategic investments in research, the company is well-positioned to advance its mission of transforming patient care through cutting-edge cell therapies.

Latest News: For the most updated information on SQZ Biotechnologies' performance, events, and developments, visit the StockTitan website to stay informed.

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SQZ Biotechnologies announced significant advancements in its point-of-care (POC) manufacturing system, achieving a 55% reduction in processing time per batch, now under 6 hours. The first clinical application is anticipated with an IND submission for celiac disease in the first half of 2023. Presentations at ASGCT 2022 highlighted the potential for cell therapies across multiple disease areas using their Cell Squeeze® technology, which shows promise for efficient delivery and editing of various cell types, enhancing therapeutic accessibility.

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SQZ Biotechnologies (SQZ) has announced its first quarter 2022 financial results, highlighting significant developments. The FDA granted Fast Track Designation for the lead APC clinical candidate SQZ-PBMC-HPV and IND clearance to initiate a Phase 1/2 trial for the eAPC candidate targeting HPV16+ solid tumors. Total revenue for the quarter was $2.9 million, a decrease from $5.5 million in Q1 2021. R&D expenses rose to $17 million, and net loss increased to $21 million from $15.4 million in 2021. As of March 31, 2022, the company had $122.9 million in cash, sufficient to fund operations through mid-2023.

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SQZ Biotechnologies (NYSE: SQZ) announced a live R&D investor event on May 19, 2022, from 4:05 - 5:30 p.m. ET, focusing on its point-of-care manufacturing system and its SQZ® TAC clinical development program for celiac disease, with an FDA application expected in early 2023. Collaboration with STEMCELL Technologies will be part of the discussion, alongside a fireside chat featuring notable experts from MIT and the company leadership. The event will be accessible both onsite and virtually, with a replay available afterward.

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SQZ Biotechnologies (NYSE: SQZ) announced promising results from its point-of-care (POC) manufacturing platform, capable of producing cell therapies in under 10 hours. The company is collaborating with STEMCELL Technologies to develop a research-use-only (RUO) system that enhances access to cell engineering capabilities. SQZ plans to present data on its POC system and hematopoietic stem cell engineering at the 2022 ASGCT Annual Meeting on May 18. The technology aims to improve the accessibility and cost-effectiveness of cell therapies, supporting advancements in the field.

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SQZ Biotechnologies (NYSE: SQZ) announced CEO Armon Sharei will present at the Bank of America Securities 2022 Healthcare Conference on May 10 in Las Vegas, NV, and at the H.C. Wainwright Global Investment Conference on May 25 in Miami, FL. Presentation details include:

  • May 10: 5:00-5:30 p.m. ET
  • May 25: 9:30-10:00 a.m. ET

Webcast links are available on the company's website, where replays will be accessible for 90 days. SQZ focuses on cell therapies for oncology, autoimmune, and infectious diseases.

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SQZ Biotechnologies (NYSE: SQZ) announced that the FDA has granted Fast Track Designation for its lead therapy candidate, SQZ-PBMC-HPV, aimed at treating HPV16+ advanced solid tumors. This designation may accelerate development and review processes for treatments for serious diseases. The candidate has shown promise in early clinical data, demonstrating potential anti-tumor activity and favorable tolerability. The ongoing Phase 1/2 clinical trial includes monotherapy and combination therapy evaluations, targeting significant treatment opportunities in oncology.

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SQZ Biotechnologies has reported significant preclinical advancements in its eAPC platform, which shows that mRNA-based expression of CD86, IL-2, and IL-12 markedly enhances CD8 T cell activity against diverse antigens, including HPV and KRAS. Data presented at the AACR 2022 Annual Meeting indicates effective T cell responses in humanized mouse models. The SQZ-eAPC-HPV candidate is currently undergoing a Phase 1/2 trial (COMMANDER-001) for HPV16+ tumors, demonstrating promising potential for improved patient outcomes through enhanced immune responses.

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SQZ Biotechnologies (NYSE: SQZ) announced that CEO Armon Sharei will present at two upcoming conferences: the 21st Annual Needham Virtual Healthcare Conference on April 13 from 9:30-10:10 AM ET, and Chardan’s 6th Annual Genetic Medicines & Cell Therapy Manufacturing Summit on April 26 from 10:00-10:25 AM ET. Webcast details for both presentations are available on the company's investors' page. SQZ Biotechnologies is a clinical-stage biotech firm focusing on cell therapies across multiple areas, including oncology and autoimmune diseases.

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SQZ Biotechnologies has published preclinical research demonstrating the effectiveness of its Tolerizing Antigen Carrier (TAC) platform in combating autoimmune diseases, particularly type 1 diabetes (T1D). The study shows that TACs effectively delayed the onset of T1D, reduced autoreactive T cells, and induced regulatory T cells. The company plans to submit an IND for celiac disease in H1 2023 and is developing a point-of-care manufacturing system for clinical trials. The findings suggest a significant potential for TACs in therapy for autoimmune diseases.

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SQZ Biotechnologies has received a $2 million SBIR Phase II grant from the National Institute of General Medical Sciences to develop methods for reprogramming immune cells into dopamine-producing neurons. This innovative approach aims to offer a new treatment paradigm for Parkinson's disease, potentially eliminating the need for chronic immunosuppression. The company's proprietary Cell Squeeze technology may enable efficient cell engineering with significant therapeutic potential beyond Parkinson's, targeting conditions like Multiple Sclerosis and Type 1 diabetes.

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FAQ

What is the market cap of SQZ (SQZ)?

The market cap of SQZ (SQZ) is approximately 12.8M.

What does SQZ Biotechnologies specialize in?

SQZ Biotechnologies specializes in developing next-generation cell therapies using its proprietary technology to enhance the immune system's ability to combat diseases.

Where was SQZ Biotechnologies founded?

SQZ Biotechnologies was spun out of MIT.

What are the core areas of focus for SQZ Biotechnologies?

The core areas of focus include developing treatments for cancer, autoimmune diseases, and other medical conditions by modifying immune cells.

What recent progress has SQZ Biotechnologies made?

SQZ Biotechnologies has made significant progress in preclinical trials and has initiated various clinical programs to address challenging medical conditions.

Who are SQZ Biotechnologies' partners?

SQZ Biotechnologies has strategic partnerships with leading pharmaceutical companies and academic institutions.

What is the financial outlook for SQZ Biotechnologies?

SQZ Biotechnologies is financially robust, with strategic investments in research and a solid balance sheet.

How does SQZ Biotechnologies aim to change patient care?

SQZ Biotechnologies aims to transform patient care by developing personalized cell therapies that harness the immune system's power to fight diseases.

What sets SQZ Biotechnologies apart from other biotech companies?

SQZ Biotechnologies' proprietary technology for precise cell modification and its focus on harnessing the immune system set it apart in the biotech field.

How can I stay updated on SQZ Biotechnologies' latest news?

For the latest updates, visit the StockTitan website and follow SQZ Biotechnologies' dedicated section.

What is the mission of SQZ Biotechnologies?

The mission of SQZ Biotechnologies is to empower cells to change lives by developing cutting-edge therapies for various diseases.

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SQZ Stock Data

12.83M
Biological Product (except Diagnostic) Manufacturing
Manufacturing
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