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SQZ Biotechnologies, spun out of MIT, is at the forefront of developing next-generation cell therapies. The company leverages its proprietary technology to harness the power of patients' immune systems to combat various diseases. SQZ Biotechnologies aims to empower cells to change lives through innovative scientific advancements.

The core business of SQZ focuses on creating groundbreaking treatments that target a wide range of medical conditions. By altering immune cells to enhance their disease-fighting capabilities, the company seeks to make significant strides in the field of immunotherapy. Their cutting-edge technology allows for precise modification of cells, paving the way for more effective and personalized treatments.

Recently, SQZ Biotechnologies has made substantial progress in its research and development efforts. Key achievements include successful preclinical trials and the initiation of various clinical programs. These programs aim to address challenging conditions like cancer and autoimmune diseases, offering new hope to patients worldwide.

Current projects at SQZ involve a robust pipeline of therapies that are in different stages of development. The company is also engaged in strategic partnerships with leading pharmaceutical companies and academic institutions. These collaborations are crucial in accelerating the development and commercialization of their innovative therapies.

Financially, SQZ Biotechnologies remains committed to driving growth and value for its shareholders. With a solid balance sheet and strategic investments in research, the company is well-positioned to advance its mission of transforming patient care through cutting-edge cell therapies.

Latest News: For the most updated information on SQZ Biotechnologies' performance, events, and developments, visit the StockTitan website to stay informed.

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SQZ Biotechnologies (NYSE: SQZ) reported its full year 2021 financial results, highlighting significant advancements in its clinical programs. The company achieved a revenue increase to $27.1 million from $21.0 million in 2020. Notable clinical milestones included the advancement of its SQZ-PBMC-HPV-101 candidate into combination therapy following positive early trial results and FDA clearance for its Enhanced APC candidate. However, the net loss widened to $68.7 million compared to $50.5 million in the previous year. Cash reserves are reported at $143.5 million.

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SQZ Biotechnologies Company (NYSE: SQZ) announced the presentation of new preclinical findings on its enhanced antigen presenting cell (eAPC) platform at the American Association for Cancer Research (AACR) Annual Meeting on April 8-13, 2022. The eAPC platform effectively delivers multiple mRNA, enhancing CD8 T cell responses against various diseases, including HPV. The FDA granted IND clearance for SQZ-eAPC-HPV, its first therapeutic candidate targeting HPV16+ solid tumors. Additionally, a Trial in Progress presentation will detail the ENVOY-001 Phase 1/2 trial of SQZ-AAC-HPV in patients with HPV-related tumors.

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SQZ Biotechnologies has published significant preclinical research regarding their Cell Squeeze® platform, demonstrating its capacity to engineer immune cells (T cells, B cells, NK cells, and monocytes) for enhanced MHC-I antigen presentation, crucial for activating killer T cells in disease treatment. This research is published in the Journal of Immunology and supports the development of clinical programs. The platform aims to advance cancer vaccines and improve patient outcomes, with FDA IND clearance for enhanced APCs.

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SQZ Biotechnologies has received FDA clearance for its investigational new drug application for SQZ-eAPC-HPV, enabling the initiation of the COMMANDER-001 Phase 1/2 clinical trial targeting HPV16+ solid tumors. This novel cell therapy candidate employs a unique engineering approach that combines multiple mRNAs. The trial aims to evaluate safety and tolerability while assessing clinical responses in patients. SQZ eAPCs have demonstrated promising preclinical results, highlighting their potential in oncological applications.

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SQZ Biotechnologies (NYSE: SQZ) has appointed John Maraganore, Ph.D., former CEO of Alnylam Pharmaceuticals, as a strategic advisor. Maraganore, known for his extensive experience in biotech, is expected to contribute significantly to the advancement of SQZ's cell therapy programs. The company aims to leverage its proprietary Cell Squeeze technology to address multiple diseases, enhancing the accessibility of therapies. CEO Armon Sharei expressed enthusiasm about the collaboration, particularly after recent positive clinical response data.

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SQZ Biotechnologies Company (NYSE: SQZ) has shared interim results from its Phase 1/2 trial for its APC therapy targeting HPV16+ tumors. A patient with checkpoint refractory head-and-neck cancer showed noteworthy clinical improvement and a complete radiographic response in the target lesion. The investigational treatment was well tolerated, with no dose-limiting toxicities observed. Notable increases in CD8 T cells and PD-L1 expression were reported. Following this progress, the trial will explore combination therapies. A conference call is scheduled for today at 8:00 a.m. ET.

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SQZ Biotechnologies (NYSE: SQZ) has reported interim results from its ongoing Phase 1/2 trial of SQZ-PBMC-HPV, a cell therapy aimed at advanced HPV16+ tumors. The highest-dose cohort showed positive outcomes, including a radiographic response in a heavily treated patient and significant increases in CD8 T cell infiltration. Notably, the therapy was well tolerated without dose-limiting toxicities. The findings will be presented at the ESMO Immuno-Oncology Congress on December 9, along with plans to advance into combination therapy with checkpoint inhibitors.

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SQZ Biotechnologies has joined the Roche Accelerator, which aims to enhance its strategic planning and market entry in China. This partnership underscores the company's ongoing collaboration with Roche, established in 2015, particularly in oncology programs. Armon Sharei, CEO of SQZ, highlighted the opportunity to address significant patient needs in China with their SQZ™ cell therapies. The collaboration aims to facilitate the exploration of local applications for their innovative cell therapy approach.

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SQZ Biotechnologies (NYSE: SQZ) announced its participation in the 4th Annual Evercore ISI HealthCONx Conference on December 1. CEO Armon Sharei, Ph.D., will provide a corporate overview during a fireside chat scheduled from 9:15-9:35 am ET. SQZ will also conduct one-on-one meetings with attendees. Details regarding the presentation and a webcast will be accessible on the company's website for 90 days post-event. SQZ focuses on advancing cell therapies across oncology, autoimmune, and infectious disease sectors.

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SQZ Biotechnologies (NYSE:SQZ) has announced its participation in the Stifel 2021 Virtual Healthcare Conference on November 17. CEO Armon Sharei, Ph.D., will provide a corporate overview and engage in one-on-one meetings. The presentation is scheduled for 10:00 am ET and will be available via webcast. Details on the webcast and corporate overview will be available on the company’s website.

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FAQ

What is the market cap of SQZ (SQZ)?

The market cap of SQZ (SQZ) is approximately 12.8M.

What does SQZ Biotechnologies specialize in?

SQZ Biotechnologies specializes in developing next-generation cell therapies using its proprietary technology to enhance the immune system's ability to combat diseases.

Where was SQZ Biotechnologies founded?

SQZ Biotechnologies was spun out of MIT.

What are the core areas of focus for SQZ Biotechnologies?

The core areas of focus include developing treatments for cancer, autoimmune diseases, and other medical conditions by modifying immune cells.

What recent progress has SQZ Biotechnologies made?

SQZ Biotechnologies has made significant progress in preclinical trials and has initiated various clinical programs to address challenging medical conditions.

Who are SQZ Biotechnologies' partners?

SQZ Biotechnologies has strategic partnerships with leading pharmaceutical companies and academic institutions.

What is the financial outlook for SQZ Biotechnologies?

SQZ Biotechnologies is financially robust, with strategic investments in research and a solid balance sheet.

How does SQZ Biotechnologies aim to change patient care?

SQZ Biotechnologies aims to transform patient care by developing personalized cell therapies that harness the immune system's power to fight diseases.

What sets SQZ Biotechnologies apart from other biotech companies?

SQZ Biotechnologies' proprietary technology for precise cell modification and its focus on harnessing the immune system set it apart in the biotech field.

How can I stay updated on SQZ Biotechnologies' latest news?

For the latest updates, visit the StockTitan website and follow SQZ Biotechnologies' dedicated section.

What is the mission of SQZ Biotechnologies?

The mission of SQZ Biotechnologies is to empower cells to change lives by developing cutting-edge therapies for various diseases.

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12.83M
Biological Product (except Diagnostic) Manufacturing
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