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Science 37 Reports Quarterly Financial Results for the Period Ended September 30, 2021

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Science 37 Holdings reported strong financial results for Q3 2021, with revenue of $14.2 million, a 116% increase year-over-year. Net bookings reached $35.9 million, up 342% compared to the same quarter in 2020. Adjusted gross profit was $4.0 million, reflecting an improved adjusted gross margin of 28.4%. However, the company faced a net loss of $14.7 million, leading to diluted earnings per share of $(3.23). For the year, total revenue guidance is set between $53.7 million and $54.2 million.

Positive
  • Revenue increased by 116% year-over-year.
  • Net bookings rose by 342% compared to Q3 2020.
  • Achieved adjusted gross profit of $4.0 million.
Negative
  • Net loss of $14.7 million, worsened from $7.7 million in 2020.
  • Diluted EPS declined to $(3.23) from $(0.90) year-over-year.
  • Adjusted EBITDA decreased to $(12.0) million compared to $(6.7) million in 2020.

LOS ANGELES, Nov. 15, 2021 (GLOBE NEWSWIRE) -- Science 37 Holdings, Inc. (Nasdaq: SNCE), (“Science 37”) the Operating System for today’s more agile clinical trials, today reported its financial results for the quarter ended September 30, 2021.

“We are pleased to have delivered another quarter of strong financial performance, marked by the early achievement of our previously communicated full year net bookings projections in September,” said David Coman, Chief Executive Officer of Science 37. “These results reflect the rapidly expanding market and the adoption of our Operating System as the industry standard. We expect this strong momentum to continue as more pharmaceutical sponsors strive to accelerate clinical trials by enabling universal access to patients and providers, anywhere.”

Quarterly Financial Highlights

  • Revenue was $14.2 million for the quarter ended September 30, 2021, a 116% increase compared to the same period in 2020.
  • Net bookings were $35.9 million for the quarter ended September 30, 2021, a 342% increase compared to the same period in 2020.
  • Adjusted Gross Profit was $4.0 million for the quarter ended September 30, 2021, compared to $(0.5) million for the same period in 2020. Adjusted Gross Margin was 28.4% for the quarter ended September 30, 2021, compared to (7.0%) percent for the same period in the prior year.
  • Net loss was $14.7 million for the quarter ended September 30, 2021, resulting in diluted earnings per share of $(3.23), compared to a net loss of $7.7 million in the same period in 2020, or diluted earnings per share of $(0.90).
  • Adjusted Net Loss was $13.9 million for the quarter ended September 30, 2021, compared to an Adjusted Net Loss of $7.8 million in the same period in 2020.
  • Adjusted EBITDA was $(12.0) million for the quarter end September 30, 2021, compared to $(6.7) million in the same period in 2020.

2021 Financial Outlook

Science 37 is providing guidance for the calendar year ending December 31, 2021 as follows:

  • Total revenues between $53.7 and $54.2 million.
  • Adjusted EBITDA between $(43.7) and $(45.7) million.
  • Basic shares outstanding are expected to be approximately 114.7 million.

The foregoing 2021 Financial Outlook statements represent management's current estimates as of the date of this release. Actual results may differ materially depending on a number of factors. Investors are urged to read the Cautionary Note Regarding Forward-Looking Statements included in this release. Management does not assume any obligation to update these estimates.

Webcast and Conference Call Details

Science 37 will host a conference call today, November 15, 2021, at 8:00 a.m. ET to discuss its quarter ended September 30, 2021 financial results. The conference call can be accessed live by dialing (844) 467-7754 for domestic callers or (270) 215-9366 for international callers and referring to Conference ID: 3157111. A live webcast of the conference call will be available on the “Investor Relations” section of the Company's website at https://investors.science37.com/. An archived copy of the webcast will be available on the website after the call.

About Science 37

Science 37’s mission is to enable universal access to clinical research—making it easier for patients and providers to participate from anywhere and helping to accelerate the development of treatments that impact patient lives. As a pioneer of decentralized clinical trials, the Science 37 Clinical Trial Operating System (OS) supports today’s more agile clinical research designs with its full stack, end-to-end technology platform and specialized networks of patient communities, telemedicine investigators, mobile nurses, remote coordinators and connected devices. Configurable to enable any study type, the Science 37 OS enables up to 15x faster enrollment, 28% better retention and 3x more people of color, as compared to the traditional site-centric clinical trial model, with industry-leading workflow orchestration, evidence generation and data harmonization. For more information, visit https://www.science37.com.

Cautionary Note Regarding Forward-Looking Statements

This press release contains certain forward-looking statements within the meaning of the federal securities laws, including statements regarding the services offered by Science 37 and the markets in which it operates, and Science 37’s projected future results. These forward-looking statements generally are identified by the words “believe,” “project,” “expect,” “anticipate,” “estimate,” “intend,” “strategy,” “future,” “opportunity,” “plan,” “may,” “should,” “will,” “would,” “will be,” “will continue,” “will likely result” and similar expressions. Forward-looking statements are predictions, projections and other statements about future events that are based on current expectations and assumptions and, as a result, are subject to risks and uncertainties. Many factors could cause actual future events to differ materially from the forward-looking statements in this press release, including but not limited to: (i) the ability to maintain the listing of Science 37’s securities on Nasdaq, (ii) volatility in the price of Science 37’s securities due to a variety of factors, including changes in the competitive and highly regulated industries in which Science 37 plans to operate, variations in performance across competitors, changes in laws and regulations affecting Science 37’s business and changes in its capital structure, (iii) the ability to recognize anticipated benefits of the business combination between Science 37, Inc. and LifeSci Acquisition II Corp. (“LifeSci”), (iv) the ability to implement business plans, forecasts, and other expectations, and to identify and realize additional opportunities, (v) the risk that Science 37 may never achieve or sustain profitability, (vi) the risk that Science 37 will need to raise additional capital to execute its business plan, which may not be available on acceptable terms or at all; and (vii) the potential adverse effects of the ongoing global COVID-19 pandemic. The foregoing list of factors is not exhaustive. You should carefully consider the foregoing factors and the other risks and uncertainties described in the “Risk Factors” section of LifeSci’s definitive proxy statement/prospectus filed with the U.S. Securities and Exchange Commission (the “SEC”) on September 24, 2021 and other documents filed by Science 37 from time to time with the SEC. These filings identify and address other important risks and uncertainties that could cause actual events and results to differ materially from those contained in the forward-looking statements. Forward-looking statements speak only as of the date they are made. Readers are cautioned not to put undue reliance on forward-looking statements, and Science 37 assumes no obligation and does not intend to update or revise these forward-looking statements, whether as a result of new information, future events, or otherwise, except as required by law. Science 37 does not give any assurance that Science 37 will achieve its expectations.

Use of Non-GAAP Financial Measures

In addition to the financial measures prepared in accordance with U.S. Generally Accepted Accounting Principles ("GAAP"), this press release contains certain non-GAAP financial measures, including adjusted gross profit, adjusted EBITDA and adjusted net income (loss). A “non-GAAP financial measure” is generally defined as a numerical measure of a company’s financial performance that excludes or includes amounts from the most directly comparable measure calculated and presented in accordance with GAAP in the statements of operations, balance sheets, or statements of cash flows of the Company. Please refer to the reconciliations of the non-GAAP financial measures to their most directly comparable GAAP measures included in this press release and the accompanying tables contained at the end of this release.

The Company defines Adjusted Gross Profit as Gross Profit excluding share-based compensation expense.

The Company defines Adjusted Net Income (including adjusted diluted earnings per share) as net income (including diluted earnings per share) excluding transactions that the Company believes are not representative of its core operations, namely: restructuring and other costs; transaction and integration-related expenses; share-based compensation expense; other income (expense), net; and gain or loss on extinguishment of debt.

EBITDA represents earnings before interest, taxes, depreciation, and amortization. The Company defines adjusted EBITDA as EBITDA, further adjusted to exclude expenses and transactions that the Company believes are not representative of its core operations, namely: restructuring and other costs; transaction and integration-related expenses; share-based compensation expense; other income (expense), net; and gain or loss on extinguishment of debt.

Each of the non-GAAP measures noted above are used by management and the Board to evaluate the Company's core operating results because they exclude certain items whose fluctuations from period-to-period do not necessarily correspond to changes in the core operations of the business.

Management believes that adjusted gross profit, adjusted EBITDA and adjusted net income (Loss) are helpful to investors, analysts, and other interested parties because they can assist in providing a more consistent and comparable overview of our operations across our historical periods. In addition, these measures are frequently used by analysts, investors, and other interested parties to evaluate and assess performance.

Non-GAAP measures have limitations in that they do not reflect all of the amounts associated with the Company's results of operations as determined in accordance with GAAP. Also, other companies might calculate these measures differently.

Contacts:

INVESTOR RELATIONS:
Caroline Paul
Gilmartin Group
investors@science37.com

MEDIA INQUIRIES:
Margie Kooman
Science 37
Phone: (984) 377-3737
Email: pr@science37.com

SCIENCE 37, INC.
CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS
(Unaudited)

  Three Months Ended
September 30,
  Nine Months Ended
September 30,
 
  2021  2020  2021  2020 
Revenues (including amounts with related parties) $14,235,697  $6,583,413  $39,221,524  $12,541,208 
                 
Operating expenses:                
Cost of revenues (including amounts with related parties)  10,318,268   7,050,897   26,245,932   10,929,068 
Selling, general and administrative  16,931,866   6,301,712   37,477,055   17,870,603 
Depreciation and amortization  1,915,517   1,141,801   5,188,586   3,162,424 
Restructuring Costs           699,473 
Total operating expenses  29,165,651   14,494,410   68,911,573   32,661,568 
                 
Loss from operations  (14,929,954)  (7,910,997)  (29,690,049)  (20,120,360)
                 
Other income:                
Interest income  151   1,554   1,424   76,019 
Sublease income (including amounts with related parties)  230,235   232,294   444,153   696,882 
Other income  7,697   (6,681)  11,954   (2,489)
Total other income  238,083   227,167   457,531   770,412 
                 
Net loss and other comprehensive loss $(14,691,871) $(7,683,830) $(29,232,518) $(19,349,948)
                 
Loss per share:                
Basic and diluted $(3.23) $(0.90) $(7.66) $(2.29)
                 
Weighted average common shares outstanding:                
Weighted average shares used to compute basic and diluted net loss per share  4,551,755   8,522,923   3,818,717   8,458,434 

SCIENCE 37, INC.
CONDENSED CONSOLIDATED BALANCE SHEETS

  (unaudited)    
  September 30,
2021
  December 31,
2020
 
Assets        
Current assets:        
Cash and cash equivalents $7,996,362  $32,478,948 
Restricted cash  -   1,004,142 
Accounts receivable, net (including amounts with related parties)  6,998,708   11,200,252 
Prepaid expenses and other current assets  4,226,079   1,364,162 
Total current assets  19,221,149   46,047,504 
         
Property and equipment, net  1,157,818   535,384 
Operating lease right-of-use assets  2,362,445   2,210,253 
Capitalized software, net  16,679,024   8,054,367 
Other assets  325,782   183,718 
Total assets $39,746,218  $57,031,226 
         
Liabilities, redeemable convertible preferred stock and stockholders’ deficit        
Current liabilities:        
Accounts payable $7,488,575  $4,401,874 
Accrued expenses and other liabilities  10,727,474   8,762,839 
Deferred revenue  6,571,281   5,136,457 
Total current liabilities  24,787,330   18,301,170 
         
Long-term liabilities:        
Long-term deferred revenue  1,055,624   427,667 
Operating lease liabilities  1,485,288   1,127,837 
Other long-term liabilities  1,541,313   223,619 
Total liabilities  28,869,555   20,080,293 
         
Redeemable convertible preferred stock:        
Preferred stock, $0.0001 par value; 41,692,230 shares authorized, 41,587,368 issued and outstanding at September 30, 2021 and December 31, 2020  143,086,271   143,086,271 
         
Stockholders’ deficit:        
Common stock, $0.0001 par value; 74,666,115 shares authorized, 4,595,168 and 2,765,097 issued and outstanding at September 30, 2021 and December 31, 2020, respectively  1,039   856 
Additional paid-in capital  4,769,114   1,611,049 
Accumulated deficit  (136,979,761)  (107,747,243)
Total stockholders’ deficit  (132,209,608)  (106,135,338)
Total liabilities, redeemable convertible preferred stock and stockholders’ deficit $39,746,218  $57,031,226 

SCIENCE 37, INC.
CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS
(Unaudited)

  Nine Months Ended September 30, 
  2021  2020 
Operating activities        
Net loss $(29,232,518) $(19,349,948)
Adjustments to reconcile net loss to net cash used in        
operating activities:        
Depreciation and amortization  5,188,586   3,162,424 
Amortization of operating ROU assets  1,153,257   1,400,294 
Stock based compensation  1,913,096   1,789 
Changes in assets and liabilities:        
Accounts receivable (including amounts with related parties)  4,201,546   (3,265,235)
Prepaid expenses and other current assets  (2,861,917)  (1,265,844)
Other assets  (142,065)  363,156 
Accounts payable  2,109,901   3,163,309 
Accrued expenses and other current liabilities  577,494   3,158,333 
Deferred revenue  2,062,780   (976,377)
Operating lease liabilities  (947,997)  (3,399,177)
Other long-term liabilities  1,317,693   143,369 
Net cash used in operating activities  (14,660,144)  (16,863,907)
         
Investing activities        
Capitalized software development costs  (11,338,853)  (3,938,788)
Purchases of fixed assets  (732,883)  (244,677)
Net cash used in investing activities  (12,071,736)  (4,183,465)
         
Financing activities        
Proceeds from Series D-1 financing, net of issuance costs     39,923,805 
Cash received from stock option exercises  1,245,152   116,240 
Net cash provided by financing activities  1,245,152   40,040,045 
         
Net decrease in cash, cash equivalents, and restricted cash  (25,486,728)  18,992,673 
Cash, cash equivalents, and restricted cash, beginning of period  33,483,090   28,808,017 
Cash, cash equivalents, and restricted cash, end of period $7,996,362  $47,800,690 
Supplemental disclosures of non-cash activities:        
Net change in accounts payable and accrued expenses and other current liabilities related to capitalized software and fixed asset additions $(2,363,941) $(208,363)
ROU asset obtained in exchange for operating lease liabilities $(1,305,448) $- 

SCIENCE 37, INC.
NON-GAAP FINANCIAL MEASURES
(Unaudited)

The following table reconciles Gross Profit (loss) to Adjusted Gross Profit:

  Three Months Ended September 30,  Nine Months Ended September 30, 
  2021  2020  2021  2020 
Gross profit $3,917,429  $(467,485) $12,975,591  $1,612,140 
Stock-based compensation expense (direct)  129,464   4,381   346,516   (70,058)
Adjusted gross profit $4,046,894  $(463,104) $13,322,108  $1,542,082 

The following table reconciles Net income (loss) to Adjusted EBITDA:

  Three Months Ended
September 30,
  Nine Months Ended
September 30,
 
  2021  2020  2021  2020 
Net loss $(14,691,871) $(7,683,830) $(29,232,518) $(19,349,948)
Interest income  (151)  (1,554)  (1,424)  (76,019)
Depreciation and amortization  1,915,517   1,141,801   5,188,586   3,162,424 
Other income (1)  (237,932)  (225,613)  (456,107)  (694,394)
Stock-based compensation expense  997,979   105,341   1,913,096   1,789 
Restructuring costs  -    -   -    699,473 
Adjusted EBITDA $(12,016,458) $(6,663,855) $(22,588,367) $(16,256,674)


(1)For the three months ended September 30, 2021 and 2020, other income includes $230,235 and $232,294, respectively, of sublease income. For the nine months ended September 30, 2021 and 2020, other income includes $444,153 and $696,882, respectively, of sublease income.

The following table reconciles Net Income (loss) to Adjusted Net Loss:



 
 Three Months Ended September 30,  Nine Months Ended September 30, 
  2021  2020  2021  2020 
Net loss $(14,691,871) $(7,683,830) $(29,232,518) $(19,349,948)
Interest income  (151)  (1,554)  (1,424)  (76,019)
Other income (1)  (237,932)  (225,613)  (456,107)  (694,394)
Stock-based compensation expense  997,979   105,341   1,913,096   1,789 
Restructuring costs  -    -   -    699,473 
Adjusted net loss $(13,931,976) $(7,805,656) $(27,776,953) $(19,419,098)


(1)For the three months ended September 30, 2021 and 2020, other income includes $230,235 and $232,294, respectively, of sublease income. For the nine months ended September 30, 2021 and 2020, other income includes $444,153 and $696,882, respectively, of sublease income.


FAQ

What were Science 37's Q3 2021 revenue figures?

Science 37 reported Q3 2021 revenue of $14.2 million, a 116% increase year-over-year.

How much did net bookings grow in Q3 2021 for SNCE?

Net bookings increased by 342% in Q3 2021, reaching $35.9 million.

What is the projected total revenue for Science 37 in 2021?

Science 37 projects total revenues between $53.7 million and $54.2 million for the year ending December 31, 2021.

How did Science 37's adjusted gross profit perform in Q3 2021?

The adjusted gross profit for Q3 2021 was $4.0 million, compared to a loss of $0.5 million in Q3 2020.

What was the diluted earnings per share for Science 37 in Q3 2021?

The diluted earnings per share for Q3 2021 was $(3.23), a decrease from $(0.90) in the same quarter in 2020.

Science 37 Holdings, Inc.

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