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Sernova Biotherapeutics Inc - SEOVF STOCK NEWS

Welcome to our dedicated page for Sernova Biotherapeutics news (Ticker: SEOVF), a resource for investors and traders seeking the latest updates and insights on Sernova Biotherapeutics stock.

Sernova Corp. is a clinical-stage biotechnology company focused on developing therapeutic cell technologies for chronic diseases like insulin-dependent diabetes, thyroid disease, and hemophilia A. The company's lead asset, the Cell Pouch System, is an implantable medical device that creates a natural vascularized tissue environment for long-term survival of therapeutic cells. Sernova's technology aims to provide a 'functional cure' for diabetes and other chronic conditions by releasing essential factors to address deficiencies in patients' bodies. The company is also working on shielding therapeutic cells from immune system attacks and developing an off-the-shelf iPSC-based islet replacement therapy in partnership with Evotec. In addition, Sernova is progressing programs for hypothyroid disease and hemophilia A using its Cell Pouch System.

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Sernova Biotherapeutics (SEOVF) has submitted an Investigational New Drug (IND) application to the FDA for its Cell Pouch bio-hybrid organ with autologous thyroid cells to treat hypothyroidism in patients undergoing total thyroidectomy. The technology aims to restore natural thyroid function without requiring immune suppression therapy.

Preclinical trials have shown promising results, demonstrating that reimplanting thyroid tissue into the pre-vascularized Cell Pouch restored thyroxine (T4) and triiodothyronine (T3) hormones to pre-thyroidectomy levels without hormone supplementation. Imaging and histology confirmed functional thyroid tissues within the Cell Pouch five months post-reimplantation.

Upon FDA clearance, Sernova plans to initiate a first-in-human clinical trial to evaluate safety, tolerability, and efficacy in patients undergoing thyroidectomy for benign nodular disease.

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Sernova Biotherapeutics (TSX: SVA) (OTCQB: SEOVF) has appointed Ross Haghighat as Chair of the Board. Haghighat brings over three decades of experience in founding, funding, and scaling technology ventures in healthcare, with expertise in driving successful innovations, strategic growth, and mergers and acquisitions in the biotechnology sector.

The company, which focuses on developing Cell Pouch bio-hybrid organ as a functional cure for Type 1 diabetes (T1D), also announced its corporate continuance from the Canada Business Corporations Act to the Business Corporations Act (British Columbia). Additionally, the company has changed its name from Sernova Corp. to Sernova Biotherapeutics Inc., while maintaining its existing ticker symbols.

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Sernova Corp. (TSX: SVA, OTCQB: SEOVF, FSE/XETRA: PSH) announced the results of its annual and special general meeting held virtually on January 10, 2025. A total of 74,190,067 common shares were voted, representing 22.8% of all outstanding shares as of November 12, 2024.

Key resolutions approved include the election of six directors: Tanya Lewis (99.6% for), Bernd Muehlenweg (99.7% for), David Paterson (99.4% for), Jonathan Rigby (99.4% for), Steven Sangha (99.4% for), and Ross Haghighat (99.5% for). KPMG LLP was appointed as auditors until the next annual meeting. Other approved resolutions include the continuance as a British Columbia , adoption of new articles, alteration of the share structure to add unlimited Preferred Shares, and an increase in the maximum number of common shares reserved for stock option grants to 50,000,000.

A conditional grant of 5,500,000 options was also approved for officers under the Option Plan. Jonathan Rigby, Sernova’s President and CEO, expressed gratitude for the shareholders' support, emphasizing the company's strengthened management team, new corporate branding, and reinvigorated corporate culture.

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Sernova Corp (TSX: SVA) (OTCQB: SEOVF) has rescheduled its annual general and special meeting of shareholders from January 7, 2025, to January 10, 2025, at 1:00pm ET. The postponement is due to a recent postal strike in Canada, which affected the company's ability to mail meeting materials through Canada Post to meet regulatory requirements. The record date remains November 12, 2024.

Shareholders must submit their proxies by 1:00 p.m. ET on January 8, 2025, either through TMX Trust Company, by telephone, or online. The Management Information Circular is available on Sernova's website and SEDAR+ profile.

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Sernova Corp (TSX: SVA, OTCQB: SEOVF) announced key strategic initiatives, including a non-binding letter of intent with HealthGena and GOLDTRACK Ventures for 'Project REEM Ventures' to explore product development and commercialization opportunities in Saudi Arabia for type 1 diabetes treatment. The company also welcomed Dr. Robert Gabbay, former Chief Scientific and Medical Officer at the American Diabetes Association, as a clinical advisor. Sernova will host a virtual Town Hall on December 13 and hold its Annual General Meeting on January 7, 2025. The company is developing a Cell Pouch bio-hybrid organ as a potential functional cure for type 1 diabetes and thyroid disorders.

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Sernova Corp. (TSX:SVA) (OTCQB:SEOVF) has announced positive interim data from its ongoing Phase I/II clinical trial of the Cell Pouch Transplant System for type 1 diabetes (T1D). The trial shows sustained insulin independence in all 6 patients of Cohort A after islet transplantation. Notably, histological data from a patient's explanted Cell Pouch after 5+ years revealed abundant, well-vascularized, functioning islets producing insulin, glucagon, and somatostatin. The Cell Pouch demonstrated no evidence of fibrosis or degradation after long-term implantation. Sernova plans to complete Cohort B soon and initiate Cohort C with an optimized immune suppression regimen. The company is also developing iPSC-derived islet-like clusters with partner Evotec for a scalable cell source.

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Sernova Corp. (TSX:SVA) (OTCQB:SEOVF), a clinical-stage biotech company focusing on regenerative medicine cell therapies, has appointed Jonathan Rigby as its new CEO. Rigby, a type 1 diabetic himself, brings extensive experience in raising capital, leading biotech companies to Nasdaq listings, and achieving strategic acquisitions. The Board believes Rigby's leadership will position Sernova to achieve its strategic milestones.

Rigby's background includes several CEO roles and board positions in biotech companies, particularly in the diabetes field. He holds a degree in biological sciences and an MBA. The appointment aims to drive Sernova's growth and realize its full potential in developing treatments for chronic diseases, including its ongoing phase 1/2a clinical trial in type 1 diabetes.

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Sernova Corp. (SVA) announces FDA Orphan Drug Designation and Rare Pediatric Disease Designation for Hemophilia A program, using Cell Pouch™ with cells corrected for Factor VIII production. The designations provide tax credits, FDA fee waivers, market exclusivity, and priority review voucher benefits, aiming to impact patients globally.
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Sernova Corp. announced an update on its conformal coating immune protection technology program, aiming to eliminate the need for chronic immunosuppression medications in islet cell transplantation for type 1 diabetes treatment. The update presented positive advancements in coating composition and process, including a 500% increase in production capacity and an 89% encapsulation yield. The final product contained 98% coated islets and demonstrated biocompatibility and glucose-stimulated insulin transfer. Pilot studies established optimal conditions for diabetes reversal, and release criteria for clinical manufacturing have been developed. Manufacturing of coating scale-up equipment is in progress.
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Sernova Corp presents positive interim results from Phase 1/2 clinical trial investigating islet allotransplantation into Cell Pouch
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FAQ

What is the current stock price of Sernova Biotherapeutics (SEOVF)?

The current stock price of Sernova Biotherapeutics (SEOVF) is $0.1388 as of February 28, 2025.

What is the market cap of Sernova Biotherapeutics (SEOVF)?

The market cap of Sernova Biotherapeutics (SEOVF) is approximately 46.0M.

What is Sernova Corp. focused on developing?

Sernova Corp. is focused on developing therapeutic cell technologies for chronic diseases like insulin-dependent diabetes, thyroid disease, and hemophilia A.

What is the Cell Pouch System developed by Sernova Corp.?

The Cell Pouch System is an implantable medical device that creates a natural vascularized tissue environment for long-term survival of therapeutic cells.

What is the goal of Sernova's technology in addressing chronic diseases?

Sernova's technology aims to provide a 'functional cure' for diabetes and other chronic conditions by releasing essential factors to address deficiencies in patients' bodies.

What partnership has Sernova entered into for developing an islet replacement therapy?

Sernova has entered into a partnership with Evotec to develop an off-the-shelf iPSC-based islet replacement therapy.

What additional programs is Sernova working on using the Cell Pouch System?

Sernova is progressing programs for hypothyroid disease resulting from thyroid gland removal and an ex vivo lentiviral Factor VIII gene therapy for hemophilia A using its Cell Pouch System.

How does Sernova plan to shield therapeutic cells from immune system attacks?

Sernova is working on a proprietary technology to shield therapeutic cells from immune system attacks with the goal of eliminating the need for chronic, systemic immunosuppression.

What is Sernova's approach to providing potentially unlimited insulin-producing cells for diabetes treatment?

Sernova's partnership with Evotec aims to provide a potentially unlimited supply of insulin-producing cells to treat millions of patients with insulin-dependent diabetes (type 1 and type 2).

What is the status of Sernova's ongoing clinical study for diabetes treatment?

Sernova's Cell Pouch System has demonstrated its potential to be a 'functional cure' for people with T1D in an ongoing Phase 1/2 clinical study at the University of Chicago, with Cell Pouches implanted for periods of more than four years and counting.

Who is the research collaboration partner of Sernova in the field of Hemophilia A?

Sernova has announced a research collaboration with Professor Antonia Follenzi, an expert in Hemophilia A at the University of Piemonte Orientale.

Where can one find more information about Sernova Corp.?

For further information, please contact Sernova Corp. directly.

What recent achievement has Sernova Corp. announced related to the Cell Pouch System?

Sernova Corp. has announced proof-of-concept data supporting the clinical evaluation of the Cell Pouch System as a potential treatment for post-operative hypothyroidism.
Sernova Biotherapeutics Inc

OTC:SEOVF

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45.99M
315.01M
3.98%
0.05%
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