Purple Biotech Reports Second Quarter 2025 Financial Results
Purple Biotech (NASDAQ/TASE: PPBT) reported Q2 2025 financial results and significant clinical progress across its pipeline. The company highlighted positive data from its CAPTN-3 tri-specific antibody platform at EACR 2025, with plans to submit an IND for IM1240 in 2026.
Key clinical achievements include statistically significant Phase 2 results for CM24 in pancreatic cancer, showing up to 78% reduction in death risk and 37.5% ORR in biomarker-selected patients. The company also initiated a Phase 2 study of NT219 in head and neck cancer.
Financial highlights include reduced R&D expenses to $0.6M (down 76.9% YoY), operating loss of $1.2M (down 64.3% YoY), and cash position of $5.6M, providing runway into Q3 2026.
Purple Biotech (NASDAQ/TASE: PPBT) ha comunicato i risultati finanziari del secondo trimestre 2025 e importanti progressi clinici nel suo portafoglio di progetti. L'azienda ha evidenziato dati positivi dalla sua piattaforma di anticorpi tri-specifici CAPTN-3 presentati all'EACR 2025, con l'intenzione di presentare una domanda IND per IM1240 nel 2026.
Tra i principali risultati clinici si segnalano risultati statistici significativi di Fase 2 per CM24 nel tumore al pancreas, con una riduzione del rischio di morte fino al 78% e un tasso di risposta obiettiva (ORR) del 37,5% nei pazienti selezionati tramite biomarcatori. L'azienda ha inoltre avviato uno studio di Fase 2 su NT219 nel tumore della testa e del collo.
I dati finanziari evidenziano una riduzione delle spese per R&S a 0,6 milioni di dollari (in calo del 76,9% su base annua), una perdita operativa di 1,2 milioni di dollari (in calo del 64,3% su base annua) e una posizione di cassa di 5,6 milioni di dollari, garantendo liquidità fino al terzo trimestre 2026.
Purple Biotech (NASDAQ/TASE: PPBT) informó los resultados financieros del segundo trimestre de 2025 y avances clínicos significativos en su cartera. La compañía destacó datos positivos de su plataforma de anticuerpos trispecíficos CAPTN-3 en el EACR 2025, con planes para presentar un IND para IM1240 en 2026.
Los logros clínicos clave incluyen resultados estadísticamente significativos de Fase 2 para CM24 en cáncer de páncreas, mostrando hasta un 78% de reducción en el riesgo de muerte y un 37.5% de tasa de respuesta objetiva (ORR) en pacientes seleccionados por biomarcadores. La compañía también inició un estudio de Fase 2 de NT219 en cáncer de cabeza y cuello.
Los aspectos financieros incluyen una reducción de los gastos en I+D a 0.6 millones de dólares (una disminución del 76.9% interanual), una pérdida operativa de 1.2 millones de dólares (una disminución del 64.3% interanual) y una posición de efectivo de 5.6 millones de dólares, proporcionando recursos hasta el tercer trimestre de 2026.
Purple Biotech (NASDAQ/TASE: PPBT)는 2025년 2분기 재무 실적과 파이프라인 전반에 걸친 중요한 임상 진전을 보고했습니다. 회사는 EACR 2025에서 CAPTN-3 삼중특이성 항체 플랫폼의 긍정적인 데이터를 강조했으며, 2026년에 IM1240에 대한 IND 제출 계획을 발표했습니다.
주요 임상 성과로는 췌장암에서 CM24의 2상 임상에서 통계적으로 유의미한 결과를 포함하며, 바이오마커로 선택된 환자에서 사망 위험이 최대 78% 감소하고 객관적 반응률(ORR)이 37.5%에 달했습니다. 또한 회사는 두경부암에서 NT219 2상 연구를 시작했습니다.
재무 하이라이트로는 연구개발비가 0.6백만 달러로 76.9% 감소했고, 영업손실은 1.2백만 달러로 64.3% 감소했으며, 현금 보유액은 5.6백만 달러로 2026년 3분기까지 운영 자금을 확보했습니다.
Purple Biotech (NASDAQ/TASE : PPBT) a publié ses résultats financiers du deuxième trimestre 2025 ainsi que des progrès cliniques significatifs sur son pipeline. La société a mis en avant des données positives de sa plateforme d’anticorps tri-spécifiques CAPTN-3 lors de l’EACR 2025, avec l’intention de soumettre un IND pour IM1240 en 2026.
Les principales avancées cliniques incluent des résultats statistiquement significatifs de phase 2 pour CM24 dans le cancer du pancréas, montrant une réduction du risque de décès pouvant atteindre 78 % et un taux de réponse objective (ORR) de 37,5 % chez des patients sélectionnés par biomarqueurs. La société a également lancé une étude de phase 2 de NT219 dans le cancer de la tête et du cou.
Les points financiers clés comprennent une réduction des dépenses en R&D à 0,6 million de dollars (en baisse de 76,9 % en glissement annuel), une perte d’exploitation de 1,2 million de dollars (en baisse de 64,3 % en glissement annuel) et une trésorerie de 5,6 millions de dollars, assurant une autonomie financière jusqu’au troisième trimestre 2026.
Purple Biotech (NASDAQ/TASE: PPBT) berichtete über die Finanzergebnisse des zweiten Quartals 2025 und bedeutende klinische Fortschritte in seiner Pipeline. Das Unternehmen hob positive Daten seiner CAPTN-3 tri-spezifischen Antikörperplattform auf dem EACR 2025 hervor und plant, 2026 einen IND-Antrag für IM1240 einzureichen.
Wichtige klinische Erfolge umfassen statistisch signifikante Phase-2-Ergebnisse für CM24 bei Bauchspeicheldrüsenkrebs, mit einer Reduktion des Sterberisikos um bis zu 78 % und einer objektiven Ansprechrate (ORR) von 37,5 % bei biomarkerselektierten Patienten. Zudem startete das Unternehmen eine Phase-2-Studie mit NT219 bei Kopf-Hals-Krebs.
Finanzielle Highlights sind reduzierte F&E-Ausgaben auf 0,6 Mio. USD (Rückgang um 76,9 % im Jahresvergleich), ein operativer Verlust von 1,2 Mio. USD (Rückgang um 64,3 % im Jahresvergleich) und eine Barreserve von 5,6 Mio. USD, die Mittel bis ins dritte Quartal 2026 sichert.
- Significant Phase 2 efficacy for CM24 with 78% reduction in death risk and 37.5% ORR in biomarker-selected patients
- Operating loss decreased by 64.3% to $1.2M compared to Q2 2024
- R&D expenses reduced by 76.9% to $0.6M year-over-year
- Cash runway extended into Q3 2026
- Cash position of only $5.6M may require additional funding
- Seeking external partners or investment for CM24 Phase 2b study
- IND submission for CAPTN-3 platform delayed until 2026
Insights
Purple Biotech shows promising data for novel cancer platforms despite losses, with strong biomarker results offering clear development pathway through 2026.
Purple Biotech's Q2 report presents a mixed but strategically focused picture of the company's oncology pipeline. The company's innovative CAPTN-3 tri-specific antibody platform is generating encouraging preclinical data demonstrating synergistic activity between its three functional arms - masked CD3, NKG2A, and tumor-associated antigen targeting. The lead candidate from this platform, IM1240, is advancing toward an IND submission expected in 2026.
Most compelling are the statistically significant efficacy results from the CM24 Phase 2 study in pancreatic cancer, where biomarker-selected patients showed dramatic improvements:
The NT219 program has also progressed, with Phase 2 trials now initiated in head and neck cancer, combining with either pembrolizumab or cetuximab.
Financially, Purple has significantly reduced its cash burn, with R&D expenses decreasing
The identification of predictive biomarkers for CM24 is particularly significant as it creates a clearer regulatory pathway and improves the risk/reward profile for this asset. The company's overall focus on immune evasion and drug resistance mechanisms targets critical unmet needs in oncology.
Purple Biotech's tri-specific antibody approach and impressive biomarker-driven results represent significant scientific advances in targeting treatment-resistant cancers.
Purple Biotech's CAPTN-3 platform represents a scientifically elegant approach to cancer immunotherapy. The tri-specific antibody design simultaneously addresses three critical challenges in immuno-oncology: conditional T-cell activation (via masked CD3), overcoming immune suppression (via NKG2A targeting), and tumor specificity (via tumor-associated antigen targeting).
The scientific value of this approach lies in its potential to enhance both specificity and efficacy while minimizing off-target toxicity - a persistent challenge with traditional T-cell engagers. The platform's spotlight at ASGCT 2025 by Dr. Amir Horowitz specifically for its targeting of the HLA-E/NKG2A axis is noteworthy, as this pathway is increasingly recognized as a critical immune checkpoint in both innate and adaptive immunity.
The CM24 data presented at AACR 2025 demonstrates the power of biomarker-driven patient selection in clinical trials. The
The NT219 program targeting IRS1/2 degradation and STAT3 inhibition addresses fundamental mechanisms of treatment resistance. The initiation of the Phase 2 study in head and neck cancer with established immunotherapy and targeted therapy combinations represents a logical clinical development strategy based on the molecular profile of these tumors.
Overall, Purple's pipeline shows a coherent scientific strategy focused on overcoming core mechanisms of treatment resistance and immune evasion that have limited the efficacy of existing cancer therapies.
Platform validating preclinical data presented at EACR 2025 for CAPTN-3 tri-specific T cell engager show synergistic activity of the platform’s masked CD3, NKG2A, and tumor-associated antigen arms
First CAPTN-3 trispecific antibody targeting novel tumor associated antigen, 5T4, advances toward first-in-human clinical trials, with IND submission expected in 2026
Positive Phase 2 data from CM24 study in biomarker-enriched pancreatic ductal adenocarcinoma (PDAC) reported at AACR 2025
NT219 Phase 2 study in head and neck cancer initiated in June 2025
REHOVOT, Israel, Aug. 06, 2025 (GLOBE NEWSWIRE) -- Purple Biotech Ltd. (“Purple Biotech” or “the Company”) (NASDAQ/TASE: PPBT), a clinical-stage company developing first-in-class therapies that seek to overcome tumor immune evasion and drug resistance, announced today financial results for the three months ended June 30, 2025.
“Our CAPTN-3 tri-specific antibody platform is differentiated not only by its masked CD3 arm for conditional T cell activation, but also by the addition of an NKG2A arm for additional T cell and NK cell activation, and a third arm targeting the tumor-associated antigen. This approach is supported by other masked TCEs showing early safety and efficacy signals,” stated Purple Biotech CEO Gil Efron. “We are focusing our activities on advancing IM1240, our first CAPTN-3 antibody, through IND-enabling studies, with the goal of initiating a Phase 1 study in 2026. Additionally, we have now established a clear path forward for CM24 for its Phase 2b study, utilizing the predictive biomarkers we observed in the Phase 2 trial, and we are seeking partners or investment to support this next study.”
Recent Clinical and Corporate Highlights:
CAPTN-3 Tri-Specific Antibody Platform
- Showcased comprehensive in vivo and ex vivo data at EACR 2025, highlighting the synergistic activity of the platform’s masked CD3, NKG2A, and tumor-associated antigen arms
- Platform was spotlighted by Dr. Amir Horowitz at ASGCT 2025 for its approach to targeting the HLA-E/NKG2A axis to selectively activate NK and CD8+ T cells, potentially addressing treatment resistance
- First investigational new drug (IND) application from the CAPTN-3 platform, for IM1240 capped-CD3x5T4xNKG2A antibody, is expected to be submitted in 2026
CM24 (α-CEACAM1 monoclonal antibody)
- Final Phase 2 data for CM24 study presented at AACR Annual Meeting 2025
- Statistically significant efficacy in biomarker subgroup analyses was observed:
78% reduction in risk of death and81% reduction in risk of progression or death in patients with defined pretreatment ranges of serum or tumor CEACAM1 and37.5% objective response rate (ORR) in this subgroup compared to0% in the respective control group61% reduction in risk of death and72% reduction in risk of progression or death in patients with defined pretreatment ranges of serum CEACAM1 or myeloperoxidase (MPO) and31% ORR in this subgroup compared to0% in the respective control group90% reduction in risk of death and81% reduction in risk of progression or death in high tumor CEACAM1 and low PD-L1 combined positive score (CPS) subgroup
- The biomarkers identified in the CM24 Phase 2 study are planned to be used for patient selection in the Phase 2b study
NT219 (IRS1/2 degrader and STAT3 blocker)
- Biomarker insights from the Phase 1 study were presented at AACR Annual Meeting 2025
- Initiated NT219 Phase 2 study in recurrent and/or metastatic squamous cell carcinoma of the head and neck (R/M SCCHN) to evaluate NT219 in combination with pembrolizumab (Keytruda) or cetuximab (Erbitux)
- Phase 2 study is led by Dr. Antonio Jimeno, Professor and Director of the Head and Neck Cancer Program, and Principal Investigator Dr. Alice Weaver, at the University of Colorado Anschutz Medical Campus
Financial Results for the Three Months Ended June 30, 2025
Research and Development Expenses were
General and Administrative Expenses were
Operating Loss was
Adjusted Operating Loss (as reconciled below) was
Finance Income, net was
Net Loss was
As of June 30, 2025, Purple Biotech had cash and cash equivalents and short-term deposits of
About Purple Biotech
Purple Biotech Ltd. (NASDAQ/TASE: PPBT) is a clinical-stage company developing first-in-class therapies that seek to overcome tumor immune evasion and drug resistance. The Company’s oncology pipeline includes CAPTN-3, CM24 and NT219. The Company is advancing CAPTN-3, a preclinical platform of conditionally activated tri-specific antibodies, which engage both T cells and NK cells to induce a strong, localized immune response within the tumor microenvironment. The cleavable capping technology confines the compound’s therapeutic activity to the local tumor microenvironment, thereby potentially increasing the anticipated therapeutic window in patients. The third arm specifically targets the Tumor Associated Antigen (TAA). The technology presents a novel mechanism of action by unleashing both innate and adaptive immune systems to mount an optimal anti-tumoral immune response. IM1240 is the first tri-specific antibody in development that targets the 5T4 antigen, which is expressed in a variety of solid tumors and is associated with advanced disease, increased invasiveness, and poor clinical outcomes. CM24 is a humanized monoclonal antibody that blocks CEACAM1, which supports tumor immune evasion and survival through multiple pathways. CEACAM1 on tumor cells, immune cells and neutrophil extracellular traps is a novel target for the treatment of multiple cancer indications. As proof of concept of these novel pathways, the Company completed a Phase 2 study for the treatment of pancreatic ductal adenocarcinoma (PDAC) with CM24 as a combination therapy with the anti-PD-1 checkpoint inhibitor nivolumab and chemotherapy, demonstrating clear and consistent improvement across all efficacy endpoints and the identification of two potential serum biomarkers and other potential tissue biomarkers. NT219 is a dual inhibitor, novel small molecule that simultaneously targets IRS1/2 and STAT3. A Phase 1 dose escalation study was concluded as a monotherapy and in combination with cetuximab, in which NT219 demonstrated anti-tumor activity in combination with cetuximab in second-line patients with recurrent and/or metastatic squamous cell carcinoma of the head and neck (R/M SCCHN). A Phase 2 study in collaboration with the University of Colorado Anschutz Medical Campus, to treat R/M SCCHN patients with NT219 in combination with cetuximab or pembrolizumab was initiated. The Company’s corporate headquarters are located in Rehovot, Israel. For more information, please visit https://purple-biotech.com/.
Non-IFRS Financial Measures
This press release includes information about certain financial measures that are not prepared in accordance with International Financial Reporting Standards (“IFRS”), including adjusted operating loss. This non-IFRS measure is not based on any standardized methodology prescribed by IFRS and is not necessarily comparable to similar measures presented by other companies. Adjusted operating loss adjusts for non-cash share-based compensation expenses. The Company’s management and board of directors utilize this non-IFRS financial measure to evaluate the Company’s performance. The Company provides this non-IFRS measure of the Company’s performance to investors because management believes that this non-IFRS financial measure, when viewed with the Company’s results under IFRS and the accompanying reconciliations, are useful in identifying underlying trends in ongoing operations. However, this non-IFRS measure is not a measure of financial performance under IFRS and, accordingly, should not be considered as an alternative to IFRS measures as indicators of operating performance. Further, this non-IFRS measure should not be considered a measure of the Company’s liquidity. A reconciliation of certain IFRS to non-IFRS financial measures has been provided in the tables included in this press release.
Forward-Looking Statements and Safe Harbor Statement
Certain statements in this press release that are forward-looking and not statements of historical fact are forward-looking statements within the meaning of the safe harbor provisions of the Private Securities Litigation Reform Act of 1995. Such forward-looking statements include, but are not limited to, statements that are not statements of historical fact, and may be identified by words such as “believe”, “expect”, “intend”, “plan”, “may”, “should”, “could”, “might”, “seek”, “target”, “will”, “project”, “forecast”, “continue” or “anticipate” or their negatives or variations of these words or other comparable words or by the fact that these statements do not relate strictly to historical matters. You should not place undue reliance on these forward-looking statements, which are not guarantees of future performance. Forward-looking statements reflect our current views, expectations, beliefs or intentions with respect to future events, and are subject to a number of assumptions, involve known and unknown risks, many of which are beyond our control, as well as uncertainties and other factors that may cause our actual results, performance or achievements to be significantly different from any future results, performance or achievements expressed or implied by the forward-looking statements. Important factors that could cause or contribute to such differences include, among others, risks relating to: the plans, strategies and objectives of management for future operations; product development for NT219, CM24 and IM1240; the process by which such early stage therapeutic candidates could potentially lead to an approved drug product is long and subject to highly significant risks, particularly with respect to a joint development collaboration; the fact that drug development and commercialization involves a lengthy and expensive process with uncertain outcomes; our ability to successfully develop and commercialize our pharmaceutical products; the expense, length, progress and results of any clinical trials; the impact of any changes in regulation and legislation that could affect the pharmaceutical industry; the difficulty in receiving the regulatory approvals necessary in order to commercialize our products; the difficulty of predicting actions of the U.S. Food and Drug Administration or any other applicable regulator of pharmaceutical products; the regulatory environment and changes in the health policies and regimes in the countries in which we operate; the uncertainty surrounding the actual market reception to our pharmaceutical products once cleared for marketing in a particular market; the introduction of competing products; patents obtained by competitors; dependence on the effectiveness of our patents and other protections for innovative products; our ability to obtain, maintain and defend issued patents; the commencement of any patent interference or infringement action against our patents, and our ability to prevail, obtain a favorable decision or recover damages in any such action; and the exposure to litigation, including patent litigation, and/or regulatory actions, and other factors that are discussed in our Annual Report on Form 20-F for the year ended December 31, 2024 and in our other filings with the U.S. Securities and Exchange Commission (“SEC”), including our cautionary discussion of risks and uncertainties under “Risk Factors” in our Registration Statements and Annual Reports. These are factors that we believe could cause our actual results to differ materially from expected results. Other factors besides those we have listed could also adversely affect us. Any forward-looking statement in this press release speaks only as of the date on which it is made. We disclaim any intention or obligation to publicly update or revise any forward-looking statement or other information contained herein, whether as a result of new information, future events or otherwise, except as required by applicable law. You are advised, however, to consult any additional disclosures we make in our reports to the SEC, which are available on the SEC’s website, https://www.sec.gov.
CONTACTS:
Company Contact:
IR@purple-biotech.com
| Purple Biotech Ltd. | |||||||
| Condensed Consolidated Unaudited Interim Statements of Financial Position | |||||||
| June 30, | December 31, | ||||||
| 2025 | 2024 | ||||||
| Note | USD thousand | USD thousand | |||||
| Assets | |||||||
| Cash and cash equivalents | 4,736 | 7,401 | |||||
| Short term deposits | 857 | 848 | |||||
| Other investments | 326 | 275 | |||||
| Other current assets | 394 | 384 | |||||
| Total current assets | 6,313 | 8,908 | |||||
| Non-current assets | |||||||
| Right of use assets | 88 | 164 | |||||
| Fixed assets, net | 135 | 124 | |||||
| Intangible assets | 27,842 | 27,842 | |||||
| Total non–current assets | 28,065 | 28,130 | |||||
| Total assets | 34,378 | 37,038 | |||||
| Liabilities | |||||||
| Lease liability - short term | 103 | 183 | |||||
| Accounts payable | 669 | 1,455 | |||||
| Warrants | 267 | 1,149 | |||||
| Other payables | 1,150 | 1,200 | |||||
| Total current liabilities | 2,189 | 3,987 | |||||
| Non-current liabilities | |||||||
| Post-employment benefit liabilities | 140 | 140 | |||||
| Total non-current liabilities | 140 | 140 | |||||
| Equity | |||||||
| Share capital, no par value | - | - | |||||
| Share premium | 149,823 | 147,631 | |||||
| Receipts on account of warrants | 21,145 | 21,145 | |||||
| Capital reserve for share-based payments | 7,366 | 8,875 | |||||
| Capital reserve from transactions with related parties | 761 | 761 | |||||
| Capital reserve from transactions with non-controlling interest | (859 | ) | (859 | ) | |||
| Accumulated loss | (146,231 | ) | (144,693 | ) | |||
| Equity attributable to owners of the Company | 32,005 | 32,860 | |||||
| Non-controlling interests | 44 | 51 | |||||
| Total equity | 32,049 | 32,911 | |||||
| Total liabilities and equity | 34,378 | 37,038 | |||||
Condensed Consolidated Unaudited Interim Statements of Operations and Other Comprehensive Income
| For the six months ended June 30, | For the three months ended June 30, | |||||||||||
| 2025 | 2024 | 2025 | 2024 | |||||||||
| USD thousand | USD thousand | USD thousand | USD thousand | |||||||||
| Research and development expenses | 1,312 | 5,814 | 553 | 2,391 | ||||||||
| General and administrative expenses | 1,329 | 1,840 | 683 | 865 | ||||||||
| Impairment loss | - | 202 | - | 202 | ||||||||
| Operating loss | 2,641 | 7,856 | 1,236 | 3,458 | ||||||||
| Finance income from financial instruments | (1,005 | ) | (1,419 | ) | (74 | ) | (946 | ) | ||||
| Finance expense | 15 | 41 | - | 24 | ||||||||
| Finance income | (106 | ) | (282 | ) | (73 | ) | (121 | ) | ||||
| Finance expense (income), net | (1,096 | ) | (1,660 | ) | (147 | ) | (1,043 | ) | ||||
| Loss for the period | 1,545 | 6,196 | 1,089 | 2,415 | ||||||||
| Other Comprehensive Profit: | ||||||||||||
| Items that will be transferred to profit or loss: | ||||||||||||
| Loss (profit) on cash flow hedges | - | 21 | - | 6 | ||||||||
| Total comprehensive loss for the period | 1,545 | 6,217 | 1,089 | 2,421 | ||||||||
| Loss attributable to: | ||||||||||||
| Owners of the Company | 1,538 | 6,167 | 1,085 | 2,405 | ||||||||
| Non-controlling interests | 7 | 29 | 4 | 10 | ||||||||
| 1,545 | 6,196 | 1,089 | 2,415 | |||||||||
| Total comprehensive loss attributable to | ||||||||||||
| Owners of the Company | 1,538 | 6,188 | 1,085 | 2,411 | ||||||||
| Non-controlling interests | 7 | 29 | 4 | 10 | ||||||||
| 1,545 | 6,217 | 1,089 | 2,421 | |||||||||
| Loss per share information | ||||||||||||
| Basic and diluted loss per Share – USD | 0.003 | 0.023 | 0.002 | 0.009 | ||||||||
| Number of Shares used in calculation | 536,905,219 | 267,722,200 | 547,243,964 | 275,320,200 | ||||||||
| Loss per ADS information (where 1 ADS represents 200 shares) | ||||||||||||
| Basic and diluted loss per ADS – USD | 0.57 | 4.6 | 0.40 | 1.80 | ||||||||
| Number of ADSs used in calculation | 2,684,526 | 1,338,611 | 2,736,220 | 1,376,601 | ||||||||
| The accompanying notes are an integral part of these condensed consolidated interim financial statements. |
| Purple Biotech Ltd. | ||||||||||||
| Condensed Consolidated Unaudited Interim Statements | ||||||||||||
| Reconciliation of Adjusted Operating Loss | ||||||||||||
| For the six months ended June 30, | For the three months ended June 30, | |||||||||||
| 2025 | 2024 | 2025 | 2024 | |||||||||
| USD thousand | USD thousand | USD thousand | USD thousand | |||||||||
| Operating loss for the period | 2,641 | 7,856 | 1,236 | 3,458 | ||||||||
| Less ESOP expenses | (152 | ) | (484 | ) | (59 | ) | (218 | ) | ||||
| 2,489 | 7,372 | 1,177 | 3,240 | |||||||||
| Condensed Consolidated Unaudited Interim Statements of Cash Flows | ||||||
| For the six months ended June 30, | ||||||
| 2025 | 2024 | |||||
| USD thousand | USD thousand | |||||
| Cash flows from operating activities: | ||||||
| Loss for the period | (1,545 | ) | (6,196 | ) | ||
| Adjustments: | ||||||
| Depreciation | 92 | 97 | ||||
| Impairment loss | - | 202 | ||||
| Finance expenses (income), net | (1,096 | ) | (1,660 | ) | ||
| Share-based payments | 152 | 484 | ||||
| (2,397 | ) | (7,073 | ) | |||
| Changes in assets and liabilities: | ||||||
| Changes in other investments and other current assets | (206 | ) | (162 | ) | ||
| Changes in trade payables | (821 | ) | (490 | ) | ||
| Changes in other payables | (98 | ) | (1,333 | ) | ||
| (1,125 | ) | (1,985 | ) | |||
| Net cash used in operating activities | (3,522 | ) | (9,058 | ) | ||
| Cash flows from investing activities: | ||||||
| Proceed from other investments | 290 | 187 | ||||
| Interest received | 85 | 207 | ||||
| Decrease(increase) in short-term deposits | (9 | ) | 5 | |||
| Acquisition of fixed assets | (2 | ) | - | |||
| Net cash provided by investing activities | 364 | 399 | ||||
| Cash flows from financing activities: | ||||||
| Proceeds from issuance ADSs | 664 | 938 | ||||
| ADS issuance expenses paid | (80 | ) | (125 | ) | ||
| Repayment of lease liability | (92 | ) | (91 | ) | ||
| Interest paid | (23 | ) | (21 | ) | ||
| Net cash provided by financing activities | 469 | 701 | ||||
| Net decrease in cash and cash equivalents | (2,689 | ) | (7,958 | ) | ||
| Cash and cash equivalents at the beginning of the period | 7,401 | 14,489 | ||||
| Effect of translation adjustments on cash and cash equivalents | 24 | (7 | ) | |||
| Cash and cash equivalents at the end of the period | 4,736 | 6,524 | ||||
| The accompanying notes are an integral part of these condensed consolidated interim financial statements. |
FAQ
What were Purple Biotech's (PPBT) key Q2 2025 financial results?
What were the Phase 2 results for Purple Biotech's CM24 drug in pancreatic cancer?
When will Purple Biotech submit the IND for its CAPTN-3 platform's first candidate?
What progress has Purple Biotech made with NT219 in head and neck cancer?
How much did Purple Biotech reduce its operating expenses in Q2 2025?
