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Metacrine Announces Resignation of Chief Medical Officer

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Metacrine, Inc. (NASDAQ:MTCR) announced the resignation of Chief Medical Officer Hubert C. Chen, M.D., effective December 31, 2021, as he pursues a new opportunity. Preston Klassen, M.D., MHS, CEO, will oversee ongoing clinical trials and future operations. The company recognizes Dr. Chen's contributions over the past three years, emphasizing the strength of the R&D team he has built to advance their inflammatory bowel disease (IBD) program into clinical phases. Metacrine continues to focus on developing therapies for gastrointestinal and liver diseases.

Positive
  • Preston Klassen's assumption of clinical operations may provide leadership continuity.
  • Strong R&D team established by Hubert Chen is expected to support ongoing projects.
Negative
  • The departure of a key executive raises concerns about continuity in leadership.

SAN DIEGO, Dec. 27, 2021 (GLOBE NEWSWIRE) -- Metacrine, Inc. (NASDAQ:MTCR), a clinical-stage biopharmaceutical company pioneering differentiated therapies for patients with gastrointestinal and liver diseases, today announced that Hubert C. Chen, M.D., chief medical officer, has resigned to pursue a new opportunity. Dr. Chen’s resignation is effective December 31, 2021. Preston Klassen, M.D., MHS, chief executive officer, is expected to assume responsibility for Metacrine’s ongoing clinical trials and future clinical operations.

“We appreciate Hubert’s significant contributions during the last three years as we moved our pipeline through several important milestones,” said Preston Klassen, M.D., MHS, CEO, Metacrine. “Hubert has established a strong team in our R&D organization that will continue to serve us well as we focus our resources on moving our IBD program into the clinic. We wish Hubert success in his future endeavors.”

About Metacrine

Metacrine, Inc. is a clinical-stage biopharmaceutical company building a pipeline of differentiated therapies to treat gastrointestinal and liver diseases. Metacrine has developed a proprietary farnesoid X receptor (FXR) platform utilizing a unique chemical scaffold, which has demonstrated an improved therapeutic profile in clinical trials. To learn more, visit www.metacrine.com.

Forward-Looking Statements

This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. Statements in this press release that are not purely historical are forward-looking statements. Such forward-looking statements include, among other things, statements about plans for initiating future clinical trials and studies. Words such as “may,” “will,” “expect,” “plan,” “aim,” “projected,” “likely,” “anticipate,” “estimate,” “intend,” “potential,” “prepare,” “perceived,” “believes” and similar expressions (as well as other words or expressions referencing future events, conditions or circumstances) are intended to identify forward-looking statements. These forward-looking statements are based on Metacrine’s expectations and assumptions that may never materialize or prove to be incorrect. Each of these forward-looking statements involves risks and uncertainties. Actual results may differ materially from those projected in any forward-looking statements due to numerous risks and uncertainties, including but not limited to: risks and uncertainties regarding regulatory approvals for MET409 or MET642; potential delays in initiating, enrolling or completing any clinical trials; potential adverse side effects or other safety risks associated with Metacrine’s product candidates; competition from third parties that are developing products for similar uses; and Metacrine’s ability to obtain, maintain and protect its intellectual property. Information regarding the foregoing and additional risks may be found in the section entitled “Risk Factors” in Metacrine’s Quarterly Report on Form 10-Q filed with the Securities and Exchange Commission (the “SEC”) on November 12, 2021, and in Metacrine’s other filings with the SEC. All forward-looking statements contained in this press release speak only as of the date on which they were made. Except as required by law, Metacrine assumes no obligation to update any forward-looking statements contained herein to reflect any change in expectations, even as new information becomes available.

Investor & Media Contact
Steve Kunszabo
Metacrine, Inc.
+1 (858) 369-7892
skunszabo@metacrine.com


FAQ

What happened at Metacrine on December 27, 2021?

Metacrine announced the resignation of Chief Medical Officer Hubert C. Chen, effective December 31, 2021.

Who will take over clinical operations at Metacrine after Dr. Chen's resignation?

Preston Klassen, M.D., MHS, the CEO, is expected to assume responsibility for clinical operations.

What impact does Hubert Chen's resignation have on Metacrine?

While Dr. Chen's departure may affect leadership continuity, the strong R&D team he built is expected to continue supporting Metacrine's projects.

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