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Karyopharm Therapeutics Inc. - KPTI STOCK NEWS

Welcome to our dedicated page for Karyopharm Therapeutics news (Ticker: KPTI), a resource for investors and traders seeking the latest updates and insights on Karyopharm Therapeutics stock.

Karyopharm Therapeutics Inc. (Nasdaq: KPTI) is a commercial-stage pharmaceutical company focused on pioneering novel cancer therapies. The company specializes in the discovery, development, and commercialization of drugs targeting nuclear export proteins for the treatment of cancer and other significant diseases. Its flagship product, XPOVIO® (selinexor), is a first-in-class, oral exportin 1 (XPO1) inhibitor and is approved in the U.S. for multiple oncology indications. These include combination therapies with Velcade® (bortezomib) and dexamethasone for multiple myeloma, as well as treatments for adult patients with relapsed or refractory diffuse large B-cell lymphoma (DLBCL).

Recent achievements highlight the company's commitment to advancing its late-stage clinical pipeline. Notably, Karyopharm has been at the forefront in evaluating selinexor's efficacy in combination therapies for multiple myeloma, endometrial cancer, and myelofibrosis. The company recently reported long-term follow-up data from a Phase 1/3 study on selinexor in combination with ruxolitinib in myelofibrosis patients, showing promising results in spleen volume and symptom reduction.

Financially, Karyopharm reported total revenue of $33.7 million for Q4 2023, with a full-year revenue of $146.0 million. Despite a competitive market, the company managed to maintain steady growth and focused resources on its high-potential pipeline. With a cash position of $192.4 million as of December 31, 2023, Karyopharm is well-positioned to continue its innovative research and development efforts.

Karyopharm's collaborations with global partners, including Antengene, Menarini, Neopharm, and FORUS, have extended the reach of XPOVIO to various international markets such as Europe, China, South Korea, and Israel. This international expansion underscores the global demand for innovative cancer therapies.

For more information, please visit www.karyopharm.com.

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Karyopharm Therapeutics Inc. (Nasdaq: KPTI) announced the grant of 26,350 restricted stock units (RSUs) to 4 newly-hired employees as part of the 2022 Inducement Stock Incentive Plan. The RSU awards will vest over three years, with 33 1/3% of the shares vesting on each anniversary of the Grant Date. The vesting is subject to the employees' continued service, and the RSU awards will be immediately exercisable in full under certain conditions.
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Karyopharm Therapeutics Inc. (Nasdaq: KPTI) will report its second quarter 2023 financial results on August 2, 2023. The company will host a conference call to discuss the financial results and other updates at 8:00 a.m. ET on the same day. Investors can access the call and webcast through the company's website or by dialing the provided numbers. This announcement indicates the company's commitment to transparency and communication with its stakeholders, which can positively impact investor confidence and stock performance.
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Karyopharm Therapeutics Inc. (KPTI) - Karyopharm Therapeutics presented updated exploratory subgroup analyses from the SIENDO study in patients with advanced or recurrent TP53 wild-type endometrial cancer at the virtual ASCO Plenary Series. The study showed promising efficacy signals for selinexor in TP53 wild-type endometrial cancer patients, with a median progression-free survival (PFS) of 27.4 months. No new safety signals were identified, and the ongoing pivotal Phase 3 study of selinexor as maintenance therapy in TP53 wild-type endometrial cancer is further supported by these results.
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Karyopharm Therapeutics Inc. announces updated exploratory subgroup analysis from the SIENDO study, providing further support for the ongoing Phase 3 study of selinexor as a maintenance therapy in patients with TP53 wild-type endometrial cancer.
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Karyopharm Therapeutics has granted 171,400 restricted stock units (RSUs) to 11 new employees. The RSU awards will vest over three years, with 33 1/3% of the shares vesting on each anniversary of the employee's employment. The awards are subject to continued service and can be exercised in full in the event of a change in control or termination.
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FAQ

What is the current stock price of Karyopharm Therapeutics (KPTI)?

The current stock price of Karyopharm Therapeutics (KPTI) is $0.635 as of December 20, 2024.

What is the market cap of Karyopharm Therapeutics (KPTI)?

The market cap of Karyopharm Therapeutics (KPTI) is approximately 82.5M.

What is Karyopharm Therapeutics' main focus?

Karyopharm Therapeutics specializes in the discovery, development, and commercialization of drugs targeting nuclear export proteins for the treatment of cancer and other major diseases.

What is XPOVIO® (selinexor)?

XPOVIO® is a first-in-class, oral exportin 1 (XPO1) inhibitor approved for the treatment of multiple oncology indications, including multiple myeloma and diffuse large B-cell lymphoma (DLBCL).

What recent achievements has Karyopharm reported?

Karyopharm recently announced promising long-term follow-up data from a Phase 1/3 study on selinexor in combination with ruxolitinib for myelofibrosis. The company also reported strong financial performance with total revenue of $146.0 million for the year 2023.

Who are Karyopharm's global partners?

Karyopharm has partnered with Antengene, Menarini, Neopharm, and FORUS to market XPOVIO in international markets, including Europe, China, South Korea, and Israel.

What are Karyopharm's financial highlights?

For Q4 2023, Karyopharm reported total revenue of $33.7 million and a full-year revenue of $146.0 million. The company had a cash position of $192.4 million as of December 31, 2023.

What are the key indications for XPOVIO?

XPOVIO is approved for use in combination with Velcade and dexamethasone for multiple myeloma, in combination with dexamethasone for heavily pre-treated multiple myeloma, and as a monotherapy for relapsed or refractory diffuse large B-cell lymphoma (DLBCL).

What is the significance of Karyopharm's research on nuclear export proteins?

Karyopharm's research targets nuclear export dysregulation, a fundamental mechanism of oncogenesis, aiming to develop therapies that inhibit this process and treat various cancers effectively.

How does Karyopharm support clinical trials and research?

Karyopharm is engaged in several mid- and late-stage clinical trials across multiple high unmet need cancer indications, including endometrial cancer and myelofibrosis. The company also collaborates with global partners and research institutions to advance its pipeline.

What are the safety considerations for XPOVIO?

Common treatment-emergent adverse events for XPOVIO include nausea, vomiting, diarrhea, and neutropenia. Patients are advised not to breastfeed during treatment. Full prescribing information is available on www.XPOVIO.com.

How can I get more information about Karyopharm's products or clinical trials?

For more information, you can contact Karyopharm's Medical Information department at +1 (888) 209-9326 or via email at medicalinformation@karyopharm.com.

Karyopharm Therapeutics Inc.

Nasdaq:KPTI

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82.52M
117.36M
6.15%
50%
15.11%
Biotechnology
Pharmaceutical Preparations
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United States of America
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