Immuneering Launches Pancreatic Cancer Advisory Board

Rhea-AI Summary

Immuneering (Nasdaq: IMRX), a clinical-stage oncology company, announced the formation of a Pancreatic Cancer Advisory Board to advance its lead clinical program, IMM-1-104. This follows recent Orphan Drug and Fast Track designations for IMM-1-104 in pancreatic cancer. The advisory board, comprising world-renowned oncology researchers, will provide strategic medical and clinical guidance. Members include Tanios Bekaii-Saab, M.D. (Mayo Clinic), Vincent Chung, M.D., FACP (City of Hope), Shubham Pant, M.D. (MD Anderson Cancer Center), and Jordan Berlin, M.D., FASCO (Vanderbilt-Ingram Cancer Center). CEO Ben Zeskind emphasized the board’s role in advancing IMM-1-104 and improving options for pancreatic cancer patients.

Positive

• Formation of Pancreatic Cancer Advisory Board with renowned oncology researchers.
• Recent Orphan Drug designation in pancreatic cancer for IMM-1-104.
• Fast Track designations in first- and second-line pancreatic cancer for IMM-1-104.

Negative

• No direct mention of clinical trial results or new financial information.

- Establishment reflects the clinical progress of IMM-1-104 and its promise in pancreatic cancer -

- Follows recent Orphan Drug designation in pancreatic cancer and Fast Track designations in first- and second-line pancreatic cancer for IMM-1-104 -

CAMBRIDGE, Mass., Dec. 19, 2024 (GLOBE NEWSWIRE) -- Immuneering Corporation (Nasdaq: IMRX), a clinical-stage oncology company seeking to develop and commercialize universal-RAS/RAF medicines for broad populations of cancer patients, today announced the formation of its Pancreatic Cancer Advisory Board. The advisory board, which comprises world-renowned oncology clinical researchers, will provide strategic medical and clinical guidance to the company as its pipeline, including lead clinical program IMM-1-104, continues to advance.

“We are delighted to welcome such an accomplished group of oncologists with significant clinical research expertise to our newly established pancreatic cancer advisory board,” said Ben Zeskind, Ph.D., Co-Founder and CEO of Immuneering. “Each member brings extensive oncology experience and knowledge of the patient journey that will be invaluable as we continue to advance IMM-1-104 further into clinical development. The formation of this board reflects the progress we are making in our efforts to develop better options for pancreatic cancer patients.”

The Company’s Pancreatic Cancer Advisory Board includes the following members:

• Tanios Bekaii-Saab, M.D., Professor of Medicine, Mayo Clinic
• Vincent Chung, M.D., FACP, Professor of Medical Oncology and Therapeutics Research, City of Hope
• Shubham Pant, M.D., Professor, GI Medical Oncology, MD Anderson Cancer Center
• Jordan Berlin, M.D., FASCO, Professor of Medicine, Director, Division of Hematology and Oncology, Department of Medicine, Vanderbilt-Ingram Cancer Center

See Immuneering’s website for additional information on the advisory board.

About IMM-1-104

IMM-1-104 aims to achieve universal-RAS activity that selectively impacts cancer cells to a greater extent than healthy cells, through Deep Cyclic Inhibition of the MAPK pathway with once-daily dosing. IMM-1-104 is currently being evaluated in a Phase 1/2a study in patients with advanced solid tumors harboring RAS mutations (NCT05585320).

About Immuneering Corporation

Immuneering is a clinical-stage oncology company seeking to develop and commercialize universal-RAS/RAF medicines for broad populations of cancer patients with an initial aim to develop a universal-RAS therapy. The Company aims to achieve universal activity through Deep Cyclic Inhibition of the MAPK pathway, impacting cancer cells while sparing healthy cells. Immuneering’s lead product candidate, IMM-1-104, is an oral, once-daily Deep Cyclic Inhibitor currently in a Phase 2a trial in patients with advanced solid tumors including those harboring RAS mutations. IMM-6-415 is an oral, twice-daily Deep Cyclic Inhibitor currently in a Phase 1/2a trial in patients with advanced solid tumors harboring RAS or RAF mutations. The company’s development pipeline also includes several early-stage programs. For more information, please visit www.immuneering.com.

Forward-Looking Statements

This press release contains forward-looking statements, including within the meaning of the Private Securities Litigation Reform Act of 1995. All statements contained in this press release that do not relate to matters of historical fact should be considered forward-looking statements, including, without limitation, statements regarding: Immuneering’s plans to develop, manufacture and commercialize its product candidates; the treatment potential and promise of IMM-1-104 and IMM-6-415, alone or in combination with other agents, including chemotherapy and pancreatic cancer; the clinical progress of IMM-1-104 and the ability of the advisory board to help advance the company’s programs; and the timing for release of additional results from the Phase 2a portion of the trial for IMM-1-104 and the Phase 1 portion of the trial for IMM-6-415.

These forward-looking statements are based on management’s current expectations. These statements are neither promises nor guarantees, but involve known and unknown risks, uncertainties and other important factors that may cause our actual results, performance or achievements to be materially different from any future results, performance or achievements expressed or implied by the forward-looking statements, including, but not limited to, the following: the risks inherent in oncology drug research and development, including target discovery, target validation, lead compound identification, and lead compound optimization; we have incurred significant losses, are not currently profitable and may never become profitable; our projected cash runway; our need for additional funding and ability to continue as a going concern; our unproven approach to therapeutic intervention; our ability to address regulatory questions and the uncertainties relating to regulatory filings, reviews and approvals; the lengthy, expensive, and uncertain process of clinical drug development, including potential delays in or failure to obtain regulatory approvals; our reliance on third parties and collaborators to conduct our clinical trials, manufacture our product candidates, and develop and commercialize our product candidates, if approved; failure to compete successfully against other drug companies; protection of our proprietary technology and the confidentiality of our trade secrets; potential lawsuits for, or claims of, infringement of third-party intellectual property or challenges to the ownership of our intellectual property; our patents being found invalid or unenforceable; costs and resources of operating as a public company; and unfavorable or no analyst research or reports.

These and other important factors discussed under the caption “Risk Factors” in our Quarterly Report on Form 10-Q for period ended September 30, 2024, and our other reports filed with the U.S. Securities and Exchange Commission, could cause actual results to differ materially from those indicated by the forward-looking statements made in this press release. Any such forward-looking statements represent management's estimates as of the date of this press release. While we may elect to update such forward-looking statements at some point in the future, except as required by law, we disclaim any obligation to do so, even if subsequent events cause our views to change. These forward-looking statements should not be relied upon as representing our views as of any date subsequent to the date of this press release.

Media Contact:
Gina Nugent
gina@nugentcommunications.com

Investor Contact:
Laurence Watts
619-916-7620
laurence@newstreetir.com

FAQ

What is the significance of Immuneering's Pancreatic Cancer Advisory Board?

The Pancreatic Cancer Advisory Board will provide strategic medical and clinical guidance to advance IMM-1-104 and improve treatment options for pancreatic cancer patients.

Who are the members of Immuneering's Pancreatic Cancer Advisory Board?

The advisory board includes Tanios Bekaii-Saab, M.D. (Mayo Clinic), Vincent Chung, M.D., FACP (City of Hope), Shubham Pant, M.D. (MD Anderson Cancer Center), and Jordan Berlin, M.D., FASCO (Vanderbilt-Ingram Cancer Center).

What recent designations has IMM-1-104 received?

IMM-1-104 has received Orphan Drug designation in pancreatic cancer and Fast Track designations in first- and second-line pancreatic cancer.

How will the advisory board impact IMM-1-104's development?

The advisory board will provide expert guidance to advance IMM-1-104 further into clinical development, aiming to develop better treatment options for pancreatic cancer patients.