IFF Pharma Solutions Unveils Breakthrough Research at AAPS 2024 PharmSci 360
IFF Pharma Solutions will showcase breakthrough research at AAPS 2024 PharmSci 360 in Salt Lake City, Utah, from Oct. 20-23. The company will demonstrate the critical role of excipients in drug formulation through scientific posters and presentations. Key advancements include:
- Nitrosamine risk mitigation
- Controlled-release performance
- Extrusion spheronization processibility and pellet quality
- Softgel stability
- Formulation of plant-based pharmaceutical gummies
IFF experts will present research on topics such as immediate-release solutions, controlled release matrix tablet formulations, and analytical methods for detecting nitrites in pharmaceutical excipients. The company aims to empower pharmaceutical manufacturers to develop safer, more effective formulations.
IFF Pharma Solutions presenterà ricerche innovative all'AAPS 2024 PharmSci 360 a Salt Lake City, Utah, dal 20 al 23 ottobre. L'azienda dimostrerà il ruolo fondamentale degli eccipienti nella formulazione dei farmaci attraverso poster scientifici e presentazioni. Le principali innovazioni includono:
- Mitigazione del rischio di nitrosamine
- Performance a rilascio controllato
- Processabilità e qualità delle pellet mediante estrusione e sferonizzazione
- Stabilità dei softgel
- Formulazione di gomme farmaceutiche a base vegetale
Gli esperti di IFF presenteranno ricerche su argomenti come soluzioni a rilascio immediato, formulazioni di compresse a matrice a rilascio controllato e metodi analitici per la rilevazione dei nitriti negli eccipienti farmaceutici. L'azienda punta a potenziare i produttori farmaceutici nello sviluppo di formulazioni più sicure ed efficaci.
IFF Pharma Solutions presentará investigaciones innovadoras en AAPS 2024 PharmSci 360 en Salt Lake City, Utah, del 20 al 23 de octubre. La compañía demostrará el rol crítico de los excipientes en la formulación de medicamentos a través de carteles científicos y presentaciones. Los avances clave incluyen:
- Mitigación del riesgo de nitrosaminas
- Rendimiento de liberación controlada
- Procesabilidad y calidad de pellets en el proceso de extrusión y esferonización
- Estabilidad de los softgels
- Formulación de gomitas farmacéuticas a base de plantas
Los expertos de IFF presentarán investigaciones sobre temas como soluciones de liberación inmediata, formulaciones de tabletas de matriz de liberación controlada y métodos analíticos para detectar nitritos en excipientes farmacéuticos. La compañía busca empoderar a los fabricantes farmacéuticos para desarrollar formulaciones más seguras y efectivas.
IFF Pharma Solutions는 10월 20일부터 23일까지 유타주 솔트레이크시티에서 열리는 AAPS 2024 PharmSci 360에서 혁신적인 연구를 선보일 예정입니다. 이 회사는 과학 포스터와 발표를 통해 약물 제형에서의 부형제의 중요성을 시연합니다. 주요 발전 사항은 다음과 같습니다:
- 나이트로사민 위험 완화
- 조절 방출 성능
- 압출 구형화의 가공성과 펠렛 품질
- 소프트젤 안정성
- 식물 기반의 제약 구미의 제형
IFF 전문가들은 즉각 방출 솔루션, 조절 방출 매트릭스 정제 제형 및 제약 부형제에서 아질산염을 검출하기 위한 분석 방법 등의 주제에 대한 연구를 발표할 것입니다. 이 회사는 제약 제조업체가 더 안전하고 효과적인 제형을 개발할 수 있도록 지원하는 것을 목표로 합니다.
IFF Pharma Solutions présentera des recherches révolutionnaires lors de l'AAPS 2024 PharmSci 360 à Salt Lake City, Utah, du 20 au 23 octobre. L'entreprise démontrera le rôle critique des excipients dans la formulation des médicaments à travers des posters scientifiques et des présentations. Les avancées clés comprennent :
- Atténuation du risque de nitrosamines
- Performance à libération contrôlée
- Processabilité et qualité des pellets par extrusion et spheronisation
- Stabilité des softgels
- Formulation de gommes pharmaceutiques à base de plantes
Les experts d'IFF présenteront des recherches sur des thèmes tels que solutions à libération immédiate, formulations de comprimés à matrice à libération contrôlée et méthodes analytiques pour détecter les nitrites dans les excipients pharmaceutiques. L'entreprise vise à permettre aux fabricants pharmaceutiques de développer des formulations plus sûres et plus efficaces.
IFF Pharma Solutions wird auf der AAPS 2024 PharmSci 360 in Salt Lake City, Utah, vom 20. bis 23. Oktober bahnbrechende Forschungen präsentieren. Das Unternehmen wird die entscheidende Rolle der Hilfsstoffe in der Arzneiformulierung durch wissenschaftliche Poster und Präsentationen demonstrieren. Zu den wichtigsten Fortschritten gehören:
- Minderung des Nitrosaminrisikos
- Kontrollierte Freisetzungsleistung
- Prozessierbarkeit und Pelletqualität durch Extrusionsspheronisation
- Stabilität von Softgels
- Formulierung von pflanzlichen Arzneimittel-Gummis
Die Experten von IFF werden Forschungen zu Themen wie sofortfreisetzenden Lösungen, kontrollierte Freisetzungsmatrix-Tablettenformulierungen und analytischen Methoden zur Detektion von Nitriten in pharmazeutischen Hilfsstoffen präsentieren. Das Unternehmen hat sich zum Ziel gesetzt, Pharmahersteller zu befähigen, sicherere und wirksamere Formulierungen zu entwickeln.
- IFF is presenting breakthrough research at a major industry event, demonstrating innovation leadership
- The company is showcasing advancements in critical areas of drug formulation and delivery
- IFF's research aims to improve drug safety and effectiveness, potentially increasing market competitiveness
- None.
Attendees can explore the pivotal role of excipients in drug delivery and gain exclusive insights
"Our latest research underscores IFF's unwavering commitment to pushing the boundaries of industry knowledge and innovation," said Paula Garcia Todd, global application development and innovation leader, Pharma Solutions, IFF. "By leveraging our deep expertise in polymers and excipients, we're empowering pharmaceutical manufacturers to develop safer, more effective formulations that keep them at the forefront of an ever-evolving industry."
Showcasing Science-Backed Technologies
IFF experts will demonstrate how excipients can support the formulation and manufacturing of safe drug products and present novel research on nitrosamine formation kinetics at the following sessions.
- Tuesday, Oct. 22, 10:30 to 11:30 a.m. Mountain Time (MT) - Two scientific posters will offer new insights into immediate-release solutions. Yeli Zhang Ph.D., senior lead applications scientist, will present "The Selection of Microcrystalline Cellulose Based Excipient in Extrusion Spheronization." Jin Zhao Ph.D., lead scientist, will present plant-based softgel superior performance in heat tolerance and stability compared to gelatin capsules under various aging conditions with his poster "Vegetarian Softgels Using SeaGel® Technology for Pharmaceutical Applications."
- Tuesday, Oct. 22, 12:30 to 1:30 p.m. MT - Nasrin Mahmoudi Ph.D., senior lead application scientist will present "Low Nitrite-Controlled Release Formulations for Water-Soluble Drugs," showcasing the development of a safe and robust controlled release matrix tablet formulation for active pharmaceutical ingredients (APIs) with vulnerable amines.
- Wednesday, Oct. 23, 10:30 to 11:30 a.m. MT on 360 Stage #3 exhibit hall - Koudi Zhu, senior analytical scientist, will discuss a highly sensitive two-dimensional ion chromatography mass spectrometry (2D-IC/MS) method for detecting trace nitrite in hydroxypropyl methylcellulose (HPMC) with her presentation "Analytical Method Advances in Measuring Nitrites in Pharmaceutical Excipients."
- Wednesday, Oct. 23, 11:30 a.m. to 12:30 p.m. MT - Mark Dreibelbis Ph.D., senior research and development scientist, will share findings that explore the hydrophilic polymer properties that predict controlled-release performance of matrix tables with "Predicting Hydroxypropyl Methylcellulose-Controlled Release Matrix Performance with Powder Dissolution Temperature."
Audience members attending poster sessions can expect exclusive insights on how different carrageenan grades affect the properties of pharmaceutical gummy formulations, and the role of lubricant ingredients in enhancing the stability of tablet pectin coatings.
- Monday, Oct. 21, 2:30 p.m. MT - "Formulation and In Vitro Evaluation of Carrageenan Based Gummies" by Dr. Nasrin Mahmoudi.
- Wednesday, Oct. 23, 12:30 p.m. MT - "Impact of Lubricant on Functional Tablet Coatings Containing Pectin" by Becca Putans, Ph.D., lead scientist.
To learn more, book a meeting with the IFF Pharma Solutions team at booth #2705 here, or visit the Knowledge Hub to discover IFF's proprietary research and latest scientific posters.
Welcome to IFF
At IFF (NYSE:IFF), an industry leader in food, beverage, health, biosciences and scent, science and creativity meet to create essential solutions for a better world – from global icons to unexpected innovations and experiences. With the beauty of art and the precision of science, we are an international collective of thinkers who partners with customers to bring scents, tastes, experiences, ingredients and solutions for products the world craves. Together, we will do more good for people and planet. Learn more at iff.com, X (Twitter) , Facebook, Instagram, and LinkedIn.
©2024 International Flavors & Fragrances Inc. (IFF). IFF, the IFF Logo, and all trademarks and service marks denoted with TM, SM or ® are owned by IFF or affiliates of IFF unless otherwise noted. All Rights Reserved.
Contact:
Emily Kaufman
Global Communications Specialist
+1 908-670-5691
emily.kaufman@iff.com
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