Humacyte, JDRF Collaborating to Develop Insulin-Producing Biovascular Pancreas to Treat Type 1 Diabetes
Humacyte, Inc. (Nasdaq: HUMA) has announced a significant collaboration with JDRF International to advance its Biovascular Pancreas (BVP) product candidate, aimed at improving treatments for type 1 diabetes (T1D). The BVP utilizes Humacyte’s innovative Human Acellular Vessel™ (HAV™) to deliver insulin-producing islets. JDRF will provide funding to facilitate the development and testing of BVP technology, which has the potential to enhance the efficiency of insulin delivery in diabetic patients. This partnership reflects a commitment towards addressing the challenges faced by T1D sufferers, with hopes of making substantial impacts on the quality of life for millions. The BVP and HAV remain investigational products and are not yet FDA-approved.
- Partnership with JDRF provides funding and support for the Biovascular Pancreas development.
- BVP technology could significantly enhance insulin delivery for type 1 diabetes treatment.
- Potential to improve the quality of life for millions suffering from T1D.
- BVP and HAV are still investigational and lack FDA approval.
NEW YORK, N.Y. and DURHAM, N.C., April 27, 2023 (GLOBE NEWSWIRE) -- Humacyte, Inc. (Nasdaq: HUMA), a biotechnology company pioneering the development and manufacturing of off-the-shelf, universally implantable bioengineered human tissues and organ systems, and JDRF International (JDRF), the leading global organization funding type 1 diabetes (T1D) research, today announced a new collaboration to advance the development of Humacyte’s Biovascular Pancreas (BVP) product candidate.
Humacyte’s BVP is designed to deliver insulin-producing islets using Humacyte’s investigational tissue-engineered blood vessel, the Human Acellular Vessel™ (HAV™). JDRF will provide Humacyte with funding to support the development and testing of the BVP.
“We are proud to be collaborating with JDRF, one of the leading organizations in the world focused on T1D research,” said Dr. Laura Niklason, founder and CEO of Humacyte. “Humacyte’s HAV technology, combined with insulin-producing islets, may constitute a groundbreaking development in the treatment of T1D in the future. Successful development of the BVP could improve the lives of millions of patients, and their families, who are suffering with this chronic and debilitating disease.”
“JDRF is committed to supporting the development of cell replacement therapies that could one day offer cures for type 1 diabetes,” said Esther Latres, JDRF vice president of research. “Through the successful replacement of lost or damaged insulin-producing cells, Humacyte’s Biovascular Pancreas has the potential to solve roadblocks in the delivery of insulin-producing cells, and change the lives of those living with the disease. We’re excited to support the ongoing development of this technology.”
The BVP would enable the delivery and survival of insulin-producing islets inside the body, using Humacyte’s bioengineered HAV as a “carrier” for delivery of the islets into the patient. Such technology could overcome many of the hurdles currently associated with implantation of islets into diabetic patients, increasing the effectiveness of treating T1D patients with islet cells. The HAV and BVP are investigational products and have not been approved for sale by the Food and Drug Administration or any international regulatory agency.
About Humacyte
Humacyte, Inc. (Nasdaq: HUMA) is developing a disruptive biotechnology platform to deliver universally implantable bioengineered human tissues, advanced tissue constructs, and organ systems designed to improve the lives of patients and transform the practice of medicine. The company develops and manufactures acellular tissues to treat a wide range of diseases, injuries, and chronic conditions. Humacyte’s initial opportunity, a portfolio of Human Acellular Vessels (HAVs), is currently in late-stage clinical trials targeting multiple vascular applications, including vascular trauma repair, arteriovenous access for hemodialysis, and peripheral arterial disease. Preclinical development is also underway in coronary artery bypass grafts, pediatric heart surgery, treatment of type 1 diabetes, and multiple novel cell and tissue applications. Humacyte’s 6mm HAV for arteriovenous (AV) access for performing hemodialysis was the first product candidate to receive the FDA’s Regenerative Medicine Advanced Therapy (RMAT) designation and has also received FDA Fast Track designation. The HAV received priority designation for the treatment of vascular trauma by the U.S. Secretary of Defense. For more information, visit www.Humacyte.com.
About JDRF
JDRF’s mission is to accelerate life-changing breakthroughs to cure, prevent and treat T1D and its complications. To accomplish this, JDRF has invested more than
About Type 1 Diabetes (T1D)
T1D is an autoimmune condition that causes the pancreas to make very little insulin or none at all. This leads to dependence on insulin therapy and the risk of short or long-term complications, which can include highs and lows in blood sugar; damage to the kidneys, eyes, nerves, and heart; and even death if left untreated. Globally, it impacts nearly 9 million people. Many believe T1D is only diagnosed in childhood and adolescence, but diagnosis in adulthood is common and accounts for nearly
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FAQ
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