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Geron Corp - GERN STOCK NEWS

Welcome to our dedicated page for Geron news (Ticker: GERN), a resource for investors and traders seeking the latest updates and insights on Geron stock.

Overview

Geron Corp (GERN) is a clinical-stage biopharmaceutical company committed to pioneering innovative therapies in the field of oncology. At the heart of its research is the development of first-in-class telomerase inhibitors, which target the underlying cellular mechanism that enables cancer cells to maintain telomere length—a key factor that contributes to their unchecked replication. This advanced approach positions Geron as a focused innovator within the broad landscape of cancer treatment development, emphasizing a precision-driven strategy that seeks to fundamentally alter how hematologic cancers are managed.

Core Business and Therapeutic Focus

The company’s main product candidate, imetelstat, is a potent, specific inhibitor designed to disrupt telomerase activity. This mechanism is central to the survival and proliferation of cancer cells, particularly in hematologic malignancies. By inhibiting telomerase, imetelstat potentially restricts the limitless division of malignant cells, thereby offering a novel therapeutic pathway for conditions such as myelodysplastic syndromes and myelofibrosis. The clinical-stage exploration of imetelstat underscores Geron Corp's commitment to transforming cancer treatment protocols and deepening our understanding of oncology therapy.

Revenue Model and Corporate Strategy

Geron Corp operates with a revenue model rooted in strategic collaborations within the pharmaceutical and biotechnology sectors. The company leverages licensing agreements, milestone-based payments, and royalty structures to support its research and operational endeavors. This multifaceted approach not only diversifies the financial underpinnings of its business strategy but also reinforces its role as an essential contributor to the oncology therapeutic landscape.

Industry Position and Research Emphasis

Within the competitive framework of biopharmaceutical research, Geron distinguishes itself by focusing exclusively on the development of innovative cancer therapies. Its research-driven approach is underscored by rigorous clinical studies and a deep understanding of the molecular biology of cancer. The company is positioned among specialized entities that are exploring targeted treatment options, relying on sophisticated scientific methodologies to bridge the gap between research innovations and practical, clinical applications.

Scientific and Clinical Expertise

Geron Corp marries scientific inquiry with clinical application through its emphasis on personalized and mechanism-based approaches in treating cancer. Its efforts in developing imetelstat represent a blend of cutting-edge research and meticulous clinical evaluation, providing insights into the potential of telomerase inhibition as a therapeutic modality. By prioritizing expert analysis over speculative claims, Geron consistently communicates an evidence-based narrative that underpins its clinical trials and strategic partnerships.

Operational and Strategic Highlights

  • Innovative Mechanism of Action: The focus on telomerase inhibition addresses a fundamental aspect of cancer cell immortality, offering a concrete rationale behind the therapeutic potential of imetelstat.
  • Focused Clinical Applications: With a targeted approach to hematologic malignancies, Geron becomes a key player in the niche area of blood cancer therapies.
  • Strategic Collaborations: Revenue generation through partnerships and licensing highlights the company’s integrated approach to research, development, and commercial strategy.
  • Scientific Rigor: The company’s operations are underpinned by robust clinical research, embodying the principles of precise and evidence-based innovation in oncology.

Conclusion

In summary, Geron Corp represents a paradigm of focused research and development within the biopharmaceutical industry. Its innovative approach to cancer treatment, primarily through the development of a first-in-class telomerase inhibitor, underscores its commitment to addressing complex oncological challenges through scientific precision and clinical expertise. This detailed exploration helps investors, analysts, and industry watchers gain a nuanced understanding of Geron Corp’s operations, setting a clear context for its role in the evolving landscape of cancer therapeutics.

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Geron Corporation (NASDAQ: GERN) appointed John F. McDonald to its Board of Directors effective September 7, 2022. McDonald, a seasoned executive with over 30 years in the biopharmaceutical industry, aims to enhance Geron's strategic and commercial objectives, particularly in advancing imetelstat. His past roles include leadership positions at Novo Nordisk and Biogen. The company's clinical focus remains on the telomerase inhibitor, imetelstat, currently undergoing two Phase 3 trials for hematologic malignancies, with top-line results expected in early January 2023.

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Geron Corporation (Nasdaq: GERN) has announced that CEO John A. Scarlett will present at three major investor conferences in New York City. The events include the Morgan Stanley 20th Annual Global Healthcare Conference on September 12, 2022, H.C. Wainwright 24th Annual Global Investment Conference on September 13, 2022, and the Baird 2022 Global Healthcare Conference on September 14, 2022. Webcasts will be available on Geron's website and archived for 30 days. Geron focuses on developing its first-in-class telomerase inhibitor, imetelstat, for treating hematologic malignancies.

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Geron Corporation (NASDAQ: GERN) has initiated the IMproveMF Phase 1 study, aimed at evaluating the combination of imetelstat and ruxolitinib in frontline myelofibrosis patients. Preclinical data indicated promising effects of this combination. The study will assess safety, pharmacokinetics, and clinical activity, with the first patient already dosed. Results are anticipated by late 2023. Imetelstat, a first-in-class telomerase inhibitor, shows potential in modifying disease progression in myelofibrosis, setting it apart from existing treatments.

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Geron Corporation (NASDAQ: GERN) announced the granting of non-statutory stock options for 365,800 shares to new employees as part of their employment inducement. The options were granted on August 17, 2022, at an exercise price of $2.15 per share, equivalent to the closing stock price on that date. These options have a 10-year term and vest over four years, rewarding continued employment. This grant follows Nasdaq Listing Rule 5635(c)(4) and is part of Geron's 2018 Inducement Award Plan.

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Geron Corporation (NASDAQ: GERN) has reported its financial results for Q2 2022, marking a net loss of $28.1 million, or $0.07 per share. Revenue for the quarter stood at $73,000, down from $107,000 in Q2 2021. The company maintains a strong balance sheet with $220 million in cash and marketable securities and has amended its loan facility to secure an additional $50 million. Key upcoming milestones include Phase 3 trial results for lower risk MDS expected in January 2023, U.S. regulatory submissions planned for 2023, and a potential commercial launch of imetelstat in 2024.

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Geron Corporation (NASDAQ: GERN) will release its Q2 2022 financial results on August 11, 2022, after the market closes. The details will be available on the company’s website. A conference call to discuss these results and upcoming milestones is scheduled for 4:30 p.m. ET on the same day. The call will be accessible via a live webcast on their site, with an archive available for 30 days. Geron is focused on developing its telomerase inhibitor, imetelstat, for hematologic malignancies and is conducting two Phase 3 trials.

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Geron Corporation (Nasdaq: GERN), a biopharmaceutical firm focused on hematologic malignancies, announced that CEO John A. Scarlett will participate in a fireside chat at the 2022 Wedbush PacGrow Healthcare Virtual Conference on Wednesday, August 10, 2022, at 12:35 p.m. ET. The event will be webcasted through the Investor Relations section on Geron's website and will be available for replay for 30 days post-event. Geron is currently advancing two Phase 3 trials: IMerge for lower risk myelodysplastic syndromes and IMpactMF for refractory myelofibrosis.

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Geron Corporation (Nasdaq: GERN) has granted non-statutory stock options for 405,800 shares to new employees as part of their employment inducements. These options, issued on July 20, 2022, have an exercise price of $1.94 per share, matching the stock's closing price on the grant date. They feature a 10-year term and vesting over four years. Geron is focused on developing imetelstat, a telomerase inhibitor, for hematologic malignancies, with two ongoing Phase 3 clinical trials: IMerge and IMpactMF.

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Geron Corporation announces an expansion of its loan facility with Hercules Capital and Silicon Valley Bank, increasing access from $75 million to $125 million. This amendment allows for an additional $50 million in potential non-dilutive capital in 2023, crucial for the company as it anticipates top-line results from the Phase 3 IMerge trial in January 2023. Funding aims to support operations and potential commercialization of imetelstat until mid-2024.

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Geron Corporation (Nasdaq: GERN) has granted a non-statutory stock option to purchase 70,000 shares of common stock to a new employee as an induction measure. This option was granted on June 15, 2022, with an exercise price of $1.30 per share, equal to the stock's closing price on that date. The option vests over four years, starting with 12.5% after six months, subject to continued employment. Geron, focused on developing a telomerase inhibitor for hematologic malignancies, is conducting two Phase 3 trials: IMerge and IMpactMF.

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FAQ

What is the current stock price of Geron (GERN)?

The current stock price of Geron (GERN) is $1.48 as of April 1, 2025.

What is the market cap of Geron (GERN)?

The market cap of Geron (GERN) is approximately 938.7M.

What is Geron Corp's primary focus?

Geron Corp is dedicated to the research and development of innovative cancer therapies, particularly through the use of first-in-class telomerase inhibitors.

How does the company plan to treat cancers?

The company is exploring the use of imetelstat, a potent telomerase inhibitor, to target the cell replication process in hematologic malignancies such as myelodysplastic syndromes and myelofibrosis.

What makes Geron Corp's approach unique?

Geron Corp employs a targeted mechanism-based strategy by inhibiting telomerase, a key enzyme that allows cancer cells limitless replication, thus addressing a fundamental aspect of cancer biology.

How does Geron generate revenue?

The company generates revenue primarily through collaboration agreements, licensing arrangements, milestone payments, and royalties, which support its research and clinical operations.

How is Geron positioned within the oncology research space?

Geron Corp is recognized for its focused research on telomerase inhibition, situating it among specialized entities within the broader oncology and biopharmaceutical sectors.

What therapeutic areas are targeted by imetelstat?

Imetelstat is primarily being developed for hematologic malignancies, with a focus on diseases such as myelodysplastic syndromes and myelofibrosis, where traditional treatment options are limited.
Geron Corp

Nasdaq:GERN

GERN Rankings

GERN Stock Data

938.67M
632.76M
0.1%
78.42%
9.17%
Biotechnology
Pharmaceutical Preparations
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United States
FOSTER CITY