Ginkgo Bioworks Reports Fourth Quarter and Full Year 2022 Financial Results
Ginkgo Bioworks Holdings reported a 52% increase in total revenue for 2022, reaching $478 million, exceeding guidance. The company added 59 new Cell Programs, marking 90% growth. Despite this, fourth-quarter revenue fell 34% to $98 million due to reduced COVID-19 testing services. Biosecurity revenue for 2022 was $334 million, up 66%. However, a loss from operations totaled $(2.2) billion, impacted by high stock-based compensation. Ginkgo forecasts at least $275 million in total revenue for 2023, with a plan to add 100 new Cell Programs and expects Biosecurity revenue of at least $100 million.
- Total revenue increased 52% to $478 million in 2022.
- 59 new Cell Programs added, representing 90% growth.
- Year-end cash balance exceeds $1.3 billion, ensuring financial flexibility.
- Biosecurity revenue rose 66% to $334 million, double the previous guidance.
- Guidance for 2023 includes adding 100 new Cell Programs.
- Fourth quarter total revenue decreased 34% to $98 million.
- Fourth quarter Biosecurity revenue declined 61% compared to the prior year.
- Loss from operations reached $(2.2) billion due to high stock-based compensation.
59 new Cell Programs added in 2022, representing
Year end cash balance of over
"We added 59 new programs to the cell programming platform in 2022 as our team delivered toward the high end of our program guidance," said
Recent Business Highlights & Strategic Positioning
- Added 20 new Cell Programs to the Foundry platform in the fourth quarter of 2022, for a total of 59 new programs in the full year, representing
90% growth over 2021 - Generated Foundry revenue of
in 2022, representing growth of$144 million 27% over 2021 - As previously announced, a subset of targeted milestones that were expected to contribute to 2022 Foundry revenue remained unearned in the fourth quarter, though Ginkgo continues to work toward the achievement of these milestones
- Concentric by Ginkgo, Ginkgo's biosecurity and public health offering, generated
in Biosecurity revenue in 2022, representing growth of$334 million 66% over 2021 and more than doubling the original guidance provided inMarch 2022 - Concentric continued to expand the Traveler-Based Genomic Surveillance program with
Centers for Disease Control and Prevention (CDC ) and XpresCheck, adding three new participating airports (for a total of seven) and completing a recent pilot initiative to detect influenza variants in addition to SARS-CoV-2 - Concentric continues to establish international partnerships, including in
Australia ,Botswana ,Qatar ,Rwanda ,Saudi Arabia , theUnited Kingdom , andUkraine , as well as multilateral partnerships with AfricaCDC and African Risk Capacity - Downstream value – which consists of potential value to Ginkgo from its Cell Engineering customers and includes potential royalties, milestone payments, and equity interests – is an important component of the financial potential of most programs, and Ginkgo added over
in aggregate revenue potential from downstream milestone payments in connection with new Cell Programs in 2022. This is in addition to the financial potential from royalties and equity consideration obtained in connection with those Cell Programs$2.0 billion - Ginkgo launched Ginkgo Enzyme Services, which aims to solve challenges for R&D teams developing enzymes, from discovery of novel enzyme activity through optimization of enzyme function and large scale manufacturing
- Ginkgo opened Bioworks7, which adds 6,600 square feet of Biosafety Level 2 (BSL-2) lab space at Ginkgo's headquarters in
Boston's Seaport District , expanding its mammalian foundry platform to provide significant runway to support new program additions in the pharma & biotech vertical
Fourth Quarter 2022 Financial Highlights
- Fourth quarter 2022 Total revenue of
, down from$98 million in the comparable prior year period, a decrease of$148 million 34% , due to the expected reduction in K-12 COVID-19 testing services - Fourth quarter 2022 Foundry revenue of
, up from$53 million in the comparable prior year period, an increase of$34 million 56% - Fourth quarter 2022 Biosecurity revenue of
, down from$45 million in the comparable prior year period, a decrease of$114 million 61% , with fourth quarter 2022 Biosecurity gross profit margin of33% - Fourth quarter 2022 Loss from operations of
(inclusive of stock-based compensation expense of$(235) million ), compared to Loss from operations of$111 million (inclusive of stock-based compensation expense of$(1,685) million ) in the comparable prior year period. The stock-based compensation expense primarily relates to the continued GAAP accounting for the modification of restricted stock units issued prior to becoming a public company, as disclosed in our annual report on Form 10-K filed with the$1,673 million SEC onMarch 29, 2022 - Fourth quarter 2022 Adjusted EBITDA of
, down from$(80) million in the comparable prior year period$1 million - Cash and cash equivalents balance as of the end of the fourth quarter of over
puts Ginkgo in a strong financial position to pursue its strategic objectives$1.3 billion
Full Year 2022 Financial Highlights
- Full year 2022 Total revenue of
, up from$478 million in the prior year, an increase of$314 million 52% - Full year 2022 Foundry revenue of
, up from$144 million in the prior year, an increase of$113 million 27% - Full year 2022 Biosecurity revenue of
, up from$334 million in the prior year, an increase of$201 million 66% , with full year 2022 Biosecurity gross profit margin of39% - Full year 2022 Loss from operations of
(inclusive of stock-based compensation expense of$(2.2) billion ), compared to$1.9 billion (inclusive of stock-based compensation expense of$(1.8) billion ) in the prior year$1.7 billion - Full year 2022 Adjusted EBITDA of
, down from$(173) million in the prior year$(106) million
Full Year 2023 Guidance
- Ginkgo expects to add 100 new Cell Programs to the Foundry platform in 2023
- Ginkgo expects Total revenue of at least
in 2023$275 million - Ginkgo expects Foundry revenue of at least
in 2023. This guidance excludes the impact of any downstream value share revenue, although Ginkgo is still working toward the achievement of downstream value share in 2023$175 million - While Biosecurity remains an uncertain business, Ginkgo expects Biosecurity revenue in 2023 of at least
, with nearly half of this revenue expected to come from emerging product lines that are more recurring in nature, such as federal and international partnerships supporting pathogen monitoring and biosecurity infrastructure development$100 million
Timing of Filing Annual Report on Form 10-K
Ginkgo became a large accelerated filer as of
As such, we will be filing a Form 12b-25 for an automatic extension to our Form 10-K filing deadline. We are working diligently to file our Annual Report as soon as practicable and within the automatic extension period of fifteen calendar days from the prescribed due date.
Conference Call Details
Ginkgo will host a videoconference today,
To ask a question ahead of the presentation, please submit your questions to @Ginkgo on
A webcast link is available on Ginkgo's Investor Relations website and a replay will be made available following the presentation.
Ginkgo Investor Website: https://investors.ginkgobioworks.com/events/
Audio-Only Dial Ins:
+1 646 876 9923 (
+1 301 715 8592 (
+1 312 626 6799 (
+1 669 900 6833 (
+1 253 215 8782 (Tacoma)
+1 346 248 7799 (
+1 408 638 0968 (
Webinar ID: 999 3790 5942
If you experience technical difficulties with any of these dial-ins or if you need international dial-in numbers, please visit our web site at https://investors.ginkgobioworks.com/events/ for updated dial-in information.
About
Forward-Looking Statements of
This press release, the presentation, and the conference call and webcast contain certain forward-looking statements within the meaning of the federal securities laws, including statements regarding our plans, strategies, current expectations, operations and anticipated results of operations, both business and financial, including the potential for future revenue related to downstream value in the form of potential future milestone payments and royalties and/or equity consideration, all of which are subject to known and unknown risks, uncertainties and other factors that may cause our actual results, performance or achievements, market trends, or industry results to differ materially from those expressed or implied by such forward-looking statements. These forward-looking statements generally are identified by the words "believe," "can," "project," "potential," "expect," "anticipate," "estimate," "intend," "strategy," "future," "opportunity," "plan," "may," "should," "will," "would," "will be," "will continue," "will likely result," and similar expressions. Forward-looking statements are predictions, projections and other statements about future events that are based on current expectations and assumptions and, as a result, are subject to risks and uncertainties. Many factors could cause actual future events to differ materially from the forward-looking statements in this document, including but not limited to: (i) volatility in the price of Ginkgo's securities due to a variety of factors, including changes in the competitive and highly regulated industries in which Ginkgo operates and plans to operate, variations in performance across competitors, and changes in laws and regulations affecting Ginkgo's business, (ii) the ability to implement business plans, forecasts, and other expectations, and to identify and realize additional business opportunities, (iii) the risk of downturns in demand for products using synthetic biology, (iv) the unpredictability of the duration of the COVID-19 pandemic and the demand for COVID-19 testing and the commercial viability of our COVID-19 testing business, (v) changes to the biosecurity industry, including due to advancements in technology, emerging competition and evolution in industry demands, standards and regulations, (vi) our ability to realize the expected benefits of merger and acquisition transactions, (vii) the outcome of any legal proceedings against Ginkgo, including as a result of recent acquisitions, (viii) our ability to realize the expected benefits from and the success of our Foundry platform programs, (ix) our ability to successfully develop engineered cells, bioprocesses, data packages or other deliverables, and (x) the product development or commercialization success of our customers. The foregoing list of factors is not exhaustive. You should carefully consider the foregoing factors and the other risks and uncertainties described in the "Risk Factors" section of Ginkgo's most recent quarterly report on Form 10-Q filed with the
Use of Non-GAAP Financial Measures
Certain of the financial measures included in this release, including Adjusted EBITDA, have not been prepared in accordance with generally accepted accounting principles ("GAAP"), and constitute "non-GAAP financial measures" as defined by the SEC. Ginkgo has included these non-GAAP financial measures because it believes they provide an additional tool for investors to use in evaluating Ginkgo's financial performance and prospects. Due to the nature and/or size of the items being excluded, such items do not reflect future gains, losses, expenses or benefits and are not indicative of our future operating performance. These non-GAAP financial measures are supplemental to, should not be considered in isolation from, or as an alternative to, financial measures determined in accordance with GAAP. In addition, these non-GAAP financial measures may differ from non-GAAP financial measures with comparable names used by other companies. See the reconciliation below for additional information regarding certain of the non-GAAP financial measures included in this release, including a description of these non-GAAP financial measures and a reconciliation of the historic measures to Ginkgo's most comparable GAAP financial measures.
Ginkgo Bioworks Contacts:
INVESTOR CONTACT:
investors@ginkgobioworks.com
MEDIA CONTACT:
press@ginkgobioworks.com
Condensed Consolidated Balance Sheets | ||||
(in thousands, except per share data, unaudited) | ||||
As of | As of | |||
2022 | 2021 | |||
Assets | ||||
Current assets: | ||||
Cash and cash equivalents | $ 1,315,792 | $ 1,550,004 | ||
Accounts receivable, net | 80,907 | 131,544 | ||
Accounts receivable - related parties | 1,558 | 4,598 | ||
Inventory, net | 4,364 | 3,362 | ||
Prepaid expenses and other current assets | 47,458 | 33,537 | ||
Total current assets | 1,450,079 | 1,723,045 | ||
Property and equipment, net | 314,773 | 145,770 | ||
Operating lease right-of-use assets | 400,762 | — | ||
Investments | 112,188 | 102,037 | ||
Equity method investments | 1,543 | 13,194 | ||
Intangible assets, net | 111,041 | 21,642 | ||
60,210 | 21,312 | |||
Other non-current assets | 88,725 | 43,990 | ||
Total assets | $ 2,070,990 | |||
Liabilities and Stockholders' Equity | ||||
Current liabilities: | ||||
Accounts payable | ||||
Deferred revenue | 47,817 | 33,240 | ||
Accrued expenses and other current liabilities | 114,694 | 93,332 | ||
Total current liabilities | 172,962 | 134,761 | ||
Non-current liabilities: | ||||
Deferred rent, net of current portion | — | 18,746 | ||
Deferred revenue, net of current portion | 174,767 | 155,991 | ||
Operating lease liabilities, non-current | 413,256 | — | ||
Lease financing obligation | — | 22,283 | ||
Warrant liabilities | 10,868 | 135,838 | ||
Other non-current liabilities | 31,191 | 35,992 | ||
Total liabilities | 803,044 | 503,611 | ||
Commitments and contingencies | ||||
Stockholders' equity: | ||||
Preferred stock, | — | — | ||
Common stock, | 190 | 161 | ||
Additional paid-in capital | 6,136,378 | 3,804,844 | ||
Accumulated deficit | (4,397,659) | (2,297,925) | ||
Accumulated other comprehensive loss | (2,632) | (1,715) | ||
1,736,277 | 1,505,365 | |||
Non-controlling interest | — | 62,014 | ||
Total stockholders' equity | 1,736,277 | 1,567,379 | ||
Total liabilities and stockholders' equity | $ 2,070,990 |
Condensed Consolidated Statements of Operations and Comprehensive Loss | |||||||||
(in thousands, except share and per share data, unaudited) | |||||||||
Three Months Ended | Year Ended | ||||||||
2022 | 2021 | 2022 | 2021 | ||||||
Foundry revenue | |||||||||
Biosecurity revenue: | |||||||||
Product | 12,431 | 8,418 | 35,455 | 23,040 | |||||
Service | 32,597 | 105,920 | 298,585 | 177,808 | |||||
Total revenue | 98,285 | 148,494 | 477,706 | 313,837 | |||||
Costs and operating expenses: | |||||||||
Cost of Biosecurity product revenue | 7,447 | 4,832 | 20,646 | 20,017 | |||||
Cost of Biosecurity service revenue | 22,771 | 61,746 | 183,570 | 109,673 | |||||
Research and development (1) | 181,155 | 985,025 | 1,052,643 | 1,149,662 | |||||
General and administrative (1) | 121,420 | 781,626 | 1,429,799 | 862,952 | |||||
Total operating expenses | 332,793 | 1,833,229 | 2,686,658 | 2,142,304 | |||||
Loss from operations | (234,508) | (1,684,735) | (2,208,952) | (1,828,467) | |||||
Other income (expense): | |||||||||
Interest income | 11,412 | 496 | 20,262 | 837 | |||||
Interest expense | 1,647 | (551) | (106) | (2,373) | |||||
Gain (loss) on equity method investments | 10,003 | (4,663) | (43,761) | (77,284) | |||||
Loss on investments | (13,354) | (14,552) | (53,335) | (11,543) | |||||
Change in fair value of warrant liabilities | 28,871 | 77,097 | 124,970 | 58,615 | |||||
Gain on settlement of partnership agreement | — | 23,826 | — | 23,826 | |||||
Gain on deconsolidation of subsidiaries | — | — | 31,889 | — | |||||
Other income (expense), net | 7,005 | (2,596) | 7,634 | (1,733) | |||||
Total other income (expense), net | 45,584 | 79,057 | 87,553 | (9,655) | |||||
Loss before income taxes | (188,924) | (1,605,678) | (2,121,399) | (1,838,122) | |||||
Income tax benefit | (14,770) | (683) | (15,027) | (1,480) | |||||
Net loss | (174,154) | (1,604,995) | (2,106,372) | (1,836,642) | |||||
Net loss attributable to non-controlling interest | 2,390 | (4,339) | (1,443) | (6,595) | |||||
Net loss attributable to Ginkgo Bioworks | |||||||||
Net loss per share attributable to Ginkgo Bioworks | |||||||||
Basic | |||||||||
Diluted | |||||||||
Weighted average common shares outstanding: | |||||||||
Basic | 1,854,951,611 | 1,531,138,824 | 1,679,061,465 | 1,359,848,803 | |||||
Diluted | 1,856,609,515 | 1,531,551,830 | 1,679,838,849 | 1,360,373,343 | |||||
Comprehensive loss: | |||||||||
Net loss | |||||||||
Other comprehensive loss: | |||||||||
Foreign currency translation adjustment | 5,278 | (838) | (917) | (1,715) | |||||
Total other comprehensive loss | 5,278 | (838) | (917) | (1,715) | |||||
Comprehensive loss | |||||||||
(1) | R&D and G&A expenses included a significant charge for stock-based compensation expense as a result of the modification | ||||||||
Three Months Ended | Year Ended | ||||||||
(in thousands) | 2022 | 2021 | 2022 | 2021 | |||||
Research and development | |||||||||
General and administrative | 43,059 | 742,543 | 1,202,099 | 757,247 | |||||
Total |
Condensed Consolidated Statements of Cash Flows | ||||
(in thousands, unaudited) | ||||
Year Ended | ||||
2022 | 2021 | |||
Cash flows from operating activities: | ||||
Net loss | ||||
Adjustments to reconcile net loss to net cash used in operating activities: | ||||
Depreciation and amortization | 42,552 | 29,076 | ||
Stock-based compensation | 1,930,641 | 1,606,020 | ||
Non-cash customer consideration | (34,263) | (24,185) | ||
Loss on equity method investments | 43,761 | 77,284 | ||
Loss on investments | 53,335 | 11,543 | ||
Change in fair value of notes receivable | (3,757) | 3,508 | ||
Change in fair value of warrant liabilities | (124,970) | (58,615) | ||
Gain on deconsolidation of subsidiaries | (31,889) | — | ||
Deferred income tax benefit | (14,609) | — | ||
Loss on disposal of equipment | 3,091 | — | ||
Non-cash lease expense | 19,082 | — | ||
Amortization of finance lease right-of-use assets | 1,871 | — | ||
Non-cash severance and retention bonus expense associated with an | 6,152 | — | ||
Other non-cash activity | 183 | (270) | ||
Changes in operating assets and liabilities: | ||||
Accounts receivable | 55,024 | (114,094) | ||
Prepaid expenses and other current assets | (8,687) | (2,981) | ||
Inventory | 164 | (626) | ||
Operating lease right-of-use assets | 13,233 | — | ||
Other non-current assets | 921 | (539) | ||
Accounts payable | (10,844) | (2,247) | ||
Accrued expenses and other current liabilities | (39,639) | 44,796 | ||
Deferred revenue, current and non-current | (36,417) | (10,498) | ||
Operating lease liabilities, current and non-current | (10,792) | — | ||
Deferred rent, non-current | — | 6,032 | ||
Other non-current liabilities | 31 | 18,620 | ||
Net cash used in operating activities | (252,198) | (253,818) | ||
Cash flows from investing activities: | ||||
Purchases of property and equipment | (52,271) | (56,521) | ||
Deconsolidation of subsidiaries - cash | (55,721) | — | ||
Business acquisitions, net of cash acquired | 82,367 | (12,040) | ||
Asset acquisitions, net of cash acquired | (7,639) | — | ||
Purchases of notes receivable | (40,000) | — | ||
Proceeds from notes receivable | 10,000 | 304 | ||
Purchase of investment in equity securities | (3,691) | (5,000) | ||
Other | (439) | — | ||
Net cash used in investing activities | (67,394) | (73,257) | ||
Cash flows from financing activities: | ||||
Proceeds from reverse recapitalization, net of redemptions of | — | 1,509,629 | ||
Proceeds from exercise of stock options | 240 | 167 | ||
Repurchases of common stock | — | (24,998) | ||
Taxes paid related to net share settlement of equity awards | (981) | (9,463) | ||
Principal payments on finance/capital leases and lease financing | (1,237) | (1,123) | ||
Contributions from non-controlling interests | — | 59,933 | ||
Proceeds from public offering, net of issuance costs | 99,303 | — | ||
Proceeds from issuance of Series E convertible preferred stock, net of | — | — | ||
Contingent consideration payment | (521) | — | ||
Payment of equity issuance costs | (1,467) | — | ||
Net cash provided by financing activities | 95,337 | 1,534,145 | ||
Effect of foreign exchange rates on cash and cash equivalents | 908 | (19) | ||
Net (decrease) increase in cash, cash equivalents and restricted cash | (223,347) | 1,207,051 | ||
Cash and cash equivalents, beginning of period | 1,550,004 | 380,801 | ||
Restricted cash, beginning of period | 42,924 | 5,076 | ||
Cash, cash equivalents and restricted cash, beginning of period | 1,592,928 | 385,877 | ||
Cash and cash equivalents, end of period | 1,315,792 | 1,550,004 | ||
Restricted cash, end of period | 53,789 | 42,924 | ||
Cash, cash equivalents and restricted cash, end of period | $ 1,369,581 | $ 1,592,928 | ||
Selected Non-GAAP Financial Measures | ||||||||||
(in thousands, unaudited) | ||||||||||
Three Months Ended | Year Ended | |||||||||
2022 | 2021 | 2022 | 2021 | |||||||
Net loss attributable to Ginkgo Bioworks | ||||||||||
Interest income | (11,412) | (496) | (20,262) | (837) | ||||||
Interest expense | (1,647) | 551 | 106 | 2,373 | ||||||
Income tax benefit | (14,770) | (683) | (15,027) | (1,480) | ||||||
Depreciation and amortization | 13,950 | 8,003 | 42,552 | 29,076 | ||||||
EBITDA | (190,423) | (1,593,281) | (2,097,560) | (1,800,915) | ||||||
Stock-based compensation (1) | 111,230 | 1,672,843 | 1,940,920 | 1,687,607 | ||||||
(Gain) loss on equity method investments (2) | (7,612) | 4,080 | 45,315 | 74,445 | ||||||
Loss on investments | 13,354 | 14,552 | 53,335 | 11,543 | ||||||
Change in fair value of warrant liabilities | (28,871) | (77,097) | (124,970) | (58,615) | ||||||
Gain on settlement of partnership agreement | — | (23,826) | — | (23,826) | ||||||
Gain on deconsolidation of subsidiaries | — | — | (31,889) | — | ||||||
Merger and acquisition related expenses (3) | 26,045 | — | 46,229 | — | ||||||
Other (4) | (3,924) | 3,291 | (4,153) | 3,712 | ||||||
Adjusted EBITDA | ||||||||||
(1) | For the years ended | ||||||||
(2) | Represents losses on equity method investments under the hypothetical liquidation at book value method, net of losses attributable | ||||||||
(3) | Represents transaction and integration costs directly related to mergers and acquisitions including (i) due diligence, legal, | ||||||||
(4) | For the year ended |
Segment Information | |||||||
(in thousands, unaudited) | |||||||
Three Months Ended | Year Ended | ||||||
2022 | 2021 | 2022 | 2021 | ||||
Revenue: | |||||||
Foundry | |||||||
Biosecurity | 45,028 | 114,338 | 334,040 | 200,848 | |||
Total revenue | 98,285 | 148,494 | 477,706 | 313,837 | |||
Segment cost of revenue: | |||||||
Biosecurity | 30,218 | 66,578 | 204,216 | 129,690 | |||
Segment research and development expense: | |||||||
Foundry | 99,886 | 46,015 | 273,356 | 160,634 | |||
Biosecurity | 590 | 1,165 | 1,937 | 31,035 | |||
Total segment research and development expense | 100,476 | 47,180 | 275,293 | 191,669 | |||
Segment general and administrative expense: | |||||||
Foundry | 63,723 | 29,504 | 168,586 | 74,407 | |||
Biosecurity | 13,670 | 9,731 | 56,353 | 31,039 | |||
Total segment general and administrative expense | 77,393 | 39,235 | 224,939 | 105,446 | |||
Segment operating income (loss): | |||||||
Foundry | (110,352) | (41,363) | (298,276) | (122,052) | |||
Biosecurity | 550 | 36,864 | 71,534 | 9,084 | |||
Total segment operating loss | (109,802) | (4,499) | (226,742) | (112,968) | |||
Operating expenses not allocated to segments: | |||||||
Stock-based compensation (1) | 111,230 | 1,672,843 | 1,940,920 | 1,687,607 | |||
Depreciation and amortization | 14,796 | 7,686 | 42,552 | 28,185 | |||
Change in fair value of contingent | (1,320) | (293) | (1,262) | (293) | |||
Loss from operations |
(1) | Includes |
View original content to download multimedia:https://www.prnewswire.com/news-releases/ginkgo-bioworks-reports-fourth-quarter-and-full-year-2022-financial-results-301760050.html
SOURCE
FAQ
What was Ginkgo Bioworks' total revenue for 2022?
How many new Cell Programs did Ginkgo Bioworks add in 2022?
What is Ginkgo Bioworks' revenue guidance for 2023?
What was the loss from operations for Ginkgo Bioworks in 2022?