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Bio-Rad Reports Fourth-Quarter and Full-Year 2021 Financial Results

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Bio-Rad Laboratories reported Q4 2021 net sales of $732.8 million, down 7.2% year-over-year, with a gross margin of 54.7%. The Life Science segment saw a 23.8% sales decline primarily due to reduced COVID-19 demand, while Clinical Diagnostics rose by 12.6%. The company experienced a net loss of $1,573.7 million or $52.59 per diluted share, impacted by equity securities valuation changes. For full-year 2021, net sales increased 14.8% to $2.92 billion with a net income of $4.24 billion.

Positive
  • Full-year net sales increased 14.8% to $2,922.5 million.
  • Clinical Diagnostics segment sales rose 12.6% in Q4 2021.
  • Non-GAAP net income for Q4 2021 was $97.0 million, or $3.21 per share.
Negative
  • Q4 2021 net sales decreased by 7.2% compared to Q4 2020.
  • Life Science segment sales dropped 23.8% in Q4 2021.
  • Net loss for Q4 2021 was $1,573.7 million, significantly impacting diluted EPS.

HERCULES, Calif.--(BUSINESS WIRE)-- Bio-Rad Laboratories, Inc. (NYSE: BIO and BIOb), a global leader of life science research and clinical diagnostic products, today announced financial results for the fourth quarter and year ended December 31, 2021.

Fourth-quarter 2021 net sales were $732.8 million, a decrease of 7.2 percent compared to $789.8 million reported for the fourth quarter of 2020. On a currency-neutral basis, quarterly sales decreased 6.9 percent compared to the same period in 2020. Fourth-quarter gross margin was 54.7 percent compared to 58.3 percent during the fourth quarter in 2020.

Life Science segment net sales for the fourth quarter were $326.6 million, a decrease of 23.8 percent compared to the same period in 2020. On a currency-neutral basis, Life Science segment sales decreased by 23.4 percent compared to the same quarter in 2020. The currency-neutral sales decline was primarily attributed to lower qPCR product revenue due to the decline in COVID-19 related demand. Fourth-quarter 2020 revenue also included a $32.0 million damages award related to intellectual property litigation.

Clinical Diagnostics segment net sales for the fourth quarter were $404.9 million, an increase of 12.6 percent compared to the same period in 2020. On a currency-neutral basis, net sales were up 12.8 percent versus the same quarter last year. The currency-neutral sales increase was primarily driven by recovery of routine testing.

Income from operations during the fourth quarter of 2021 was $107.0 million versus $175.2 million during the same quarter last year.

Net loss for the fourth quarter of 2021 was $1,573.7 million, or a loss of $52.59 per share, on a diluted basis, versus $839.1 million of net income, or $27.81 per share, on a diluted basis, during the same period in 2020. Net income for the fourth quarter of 2021 and 2020 was impacted by the recognition of changes in the fair market value of equity securities, primarily related to the holdings of our investment in Sartorius AG.

The effective tax rate for the fourth quarter of 2021 was 22.8 percent, compared to 22.2 percent for the same period in 2020. The effective tax rate reported in Q4 of 2021 was primarily affected by an unrealized loss in equity securities and the tax rate reported in Q4 of 2020 was primarily affected by an unrealized gain in equity securities.

“While year over year COVID-related sales declines cloud the picture, many of our markets in the life science segment are seeing continued strength from robust research and biopharma funding, while our clinical diagnostics business has benefited from a steady recovery from the pandemic. Like many others, supply chain constraints during the fourth quarter impacted our ability to fully meet customer demand,” said Norman Schwartz, Bio-Rad President and Chief Executive Officer.

GAAP Results

 

Q4 2021

Q4 2020

Revenue (millions)

$732.8

$789.8

Gross margin

54.7%

58.3%

Operating margin

14.6%

22.2%

Net (loss) income (millions)

($1,573.7)

$839.1

(Loss) Income per diluted share

($52.59)

$27.81

 

Non-GAAP Results

 

Q4 2021

Q4 2020

Revenue (millions)

$732.8

$757.9

Gross margin

55.4%

58.2%

Operating margin

15.4%

21.4%

Net income (millions)

$97.0

$121.0

Income per diluted share

$3.21

$4.01

A reconciliation between GAAP operating results and non-GAAP operating results is provided following the financial statements that are part of this press release. Non-GAAP adjustments include amortization of purchased intangibles; acquisition-related expenses and benefits; restructuring, impairment charges and valuation changes in equity-owned and debt securities; gains and losses on equity-method investments; significant litigation charges or benefits and legal costs; and discrete income tax events and the income tax effect on these non-GAAP adjustments.

Non-GAAP currency neutral revenue for the fourth quarter of 2021 was $732.8 million compared to $757.9 million which excludes $32.0 million from a legal settlement in the year ago period. We recognized COVID-related revenue of approximately $46 million, primarily from sales of qPCR instruments, in the fourth quarter of 2021 versus $132 million in 2020. Core revenue, which we define as non-GAAP currency neutral revenue and excluding COVID-related sales, increased 10.2 percent.

Non-GAAP net income and non-GAAP diluted income per share (non-GAAP EPS) are non-GAAP measures that exclude certain items detailed later in this press release under the heading “Non-GAAP Reporting.”

Non-GAAP net income for the fourth quarter of 2021 was $97.0 million, or $3.21 per share, on a diluted basis, compared to $121.0 million, or $4.01 per share, on a diluted basis, during the same period in 2020.

The non-GAAP effective tax rate for the fourth quarter of 2021 was 20.3 percent, compared to 24.3 percent for the same period in 2020. The lower rate in 2021 was driven by the geographic mix of earnings.

The following table represents a reconciliation of Bio-Rad’s reported net income (loss) and diluted income (loss) per share to non-GAAP net income and non-GAAP diluted income per share for the three months and full year ended December 31, 2021 and 2020:

(in thousands, except per share data)

Three Months Ended
December 31,

Year Ended
December 31,

 

2021

2020

2021

2020

 

GAAP net (loss) income

($1,573,659)

$839,102

$4,245,902

$3,806,267

Legal Settlements

(26,297)

(28,619)

(26,297)

Amortization of purchased intangibles

6,498

7,032

27,530

27,289

Legal matters

874

6,313

16,375

16,708

Acquisition related benefits

(3,323)

(40)

(4,160)

Restructuring (benefits) costs

(3,510)

(94)

64,289

(921)

Valuation loss (gain) on equity-owned and debt securities

2,152,505

(904,316)

(4,926,248)

(4,495,825)

Loss on equity-method investments

1,615

2,072

7,194

4,706

Other non-recurring items

1,909

1,909

(11,680)

Income tax effect on non-GAAP adjustments

(489,188)

200,524

1,064,912

1,001,155

Non-GAAP net income

$97,044

$121,013

$473,204

$317,242

 

 

 

 

 

GAAP diluted (loss) income per share

($52.59)

$27.81

$140.56

$126.20

 

Non-GAAP diluted income per share

$3.21

$4.01

$15.66

$10.52

Full Year 2021 Results

On a reported basis, net sales for the full year 2021 increased 14.8 percent to $2,922.5 million compared to $2,545.6 million for the same period in 2020. On a currency-neutral basis, net sales grew 12.7 percent. Full year reported net sales for the Life Science segment were $1,400.8 million, an increase of 13.7 percent compared to 2020. On a currency-neutral basis, sales increased 12.0 percent versus 2020. Full-year reported net sales for the Clinical Diagnostics segment were $1,515.9 million, an increase of 16.1 percent compared to 2020, or an increase of 13.6 percent on a currency-neutral basis.

Full-year gross margin was 56.1 percent, compared to 56.5 percent during the same period in 2020.

Net income for 2021 was $4,245.9 million, or $140.56 per share, on a fully diluted basis, compared to $3,806.3 million, or $126.20 per share, during the same period in 2020.

The effective tax rate in 2021 was 21.9 percent compared to 22.4 percent in 2020. The tax rate in 2021 and 2020 was affected by an unrealized gain in equity securities.

Non-GAAP currency neutral revenue for the full-year 2021 was $2,890.7 million compared to $2,513.7 million which excludes legal settlements totaling $32.0 million each year. We recognized 2021 COVID-related revenue of approximately $266 million, primarily from sales of qPCR instruments, compared to $318 million in 2020. Excluding COVID-related revenues and the legal settlements, core revenue increased 17.0 percent on a currency neutral basis.

Non-GAAP net income for 2021 was $473.2 million, or $15.66 per share, compared to $317.2 million, or $10.52 per share, during the same period in 2020.

"We successfully managed through the pandemic environment and are pleased with our overall performance for 2021,” Mr. Schwartz said. “With our core business returning to normal, we expect our COVID-related revenue to continue to taper off, making for a fairly smooth transition in the coming year. We would like to recognize employees across our organization who have been critical in supporting our customers during this last year. Our achievements in 2021 give us a solid base for growth as we head into the new year.”

2021 Full-Year Highlights

  • Full-year sales were $2,922.5 million compared to $2,545.6 million for the full year of 2020. After normalizing for the impact of currency, full-year sales increased 12.7 percent.
  • Year-to-date net income for 2021 was $4,245.9 million, or $140.56 per share, on a fully diluted basis, compared to $3,806.3 million, or $126.20 per share, during the same period in 2020.
  • The company implemented a strategy-driven restructuring program in Europe to improve operating performance.
  • We expanded our quality controls portfolio with the introduction of a complete menu of independent Quality Control ready-to-use reagents – InteliQ – designed to increase workflow efficiency for high-volume labs.
  • In June, Bio-Rad launched its PREvalence™ ddPCR® SARS-CoV-2 Wastewater Quantification Kit, a sensitive, accurate, and cost-effective tool used to detect SARS-CoV-2 in a community’s wastewater.
  • In July, Bio-Rad announced a partnership with Seegene, Inc. for the clinical development and commercialization of infectious disease molecular diagnostic products for the U.S. market.
  • In July, Bio-Rad and 10x Genomics, Inc. reached a final settlement to resolve long-running litigation. The settlement includes a global patent cross-license for patents held by both Bio-Rad and 10x Genomics, resolving outstanding issues in the field of single-cell genomics.
  • In October, Bio-Rad acquired Dropworks who is developing a droplet-based digital PCR system that will provide an entry level digital PCR workflow for life science research and diagnostic applications.
  • In December, Bio-Rad announced the appointment of Simon May as Executive Vice President and President of the Life Science Group. He will provide leadership and management of the overall strategy and business direction for the company's Life Science Group.

2022 Financial Outlook

For the full year 2022, the company anticipates non-GAAP currency-neutral revenue growth of approximately 1.0 to 2.0 percent and an estimated non-GAAP operating margin of approximately 19.0 percent. Management will discuss this outlook in greater detail on the fourth-quarter and full-year 2021 financial results conference call.

“Looking ahead to 2022, we anticipate another year of progress, building on the operating efficiencies we achieved this year,” Mr. Schwartz said. “While regional COVID upswings still persist and can impact our supply chain and order flow, we believe that we are well positioned to build on our recent momentum as we continue to return to normalcy and execute our growth strategies.”

Use of Non-GAAP Reporting and Currency-Neutral

In addition to the financial measures prepared in accordance with generally accepted accounting principles (GAAP), we use certain non-GAAP financial measures, including non-GAAP net income and non-GAAP EPS, which exclude amortization of acquisition-related intangible assets, certain acquisition-related expenses and benefits, restructuring charges, asset impairment charges, valuation changes of equity-owned and debt securities, gains and losses on equity-method investments, and significant legal-related charges or benefits and associated legal costs. Non-GAAP net income and non-GAAP EPS also exclude certain other gains and losses that are either isolated or cannot be expected to occur again with any predictability, tax provisions/benefits related to the previous items, and significant discrete tax events. We exclude the above items because they are outside of our normal operations and/or, in certain cases, are difficult to forecast accurately for future periods.

We utilize a number of different financial measures, both GAAP and non-GAAP, in analyzing and assessing the overall performance of our business, in making operating decisions, forecasting and planning for future periods, and determining payments under compensation programs. We consider the use of the non-GAAP measures to be helpful in assessing the performance of the ongoing operation of our business. We believe that disclosing non-GAAP financial measures provides useful supplemental data that, while not a substitute for financial measures prepared in accordance with GAAP, allows for greater transparency in the review of our financial and operational performance. We also believe that disclosing non-GAAP financial measures provides useful information to investors and others in understanding and evaluating our operating results and future prospects in the same manner as management and in comparing financial results across accounting periods and to those of peer companies. More specifically, management adjusts for the excluded items for the following reasons:

Amortization of purchased intangible assets: we do not acquire businesses and assets on a predictable cycle. The amount of purchase price allocated to purchased intangible assets and the term of amortization can vary significantly and are unique to each acquisition or purchase. We believe that excluding amortization of purchased intangible assets allows the users of our financial statements to better review and understand the historic and current results of our operations, and also facilitates comparisons to peer companies.

Acquisition-related expenses and benefits: we incur expenses or benefits with respect to certain items associated with our acquisitions, such as transaction costs, professional fees for assistance with the transaction; valuation or integration costs; changes in the fair value of contingent consideration, gain or loss on settlement of pre-existing relationships with the acquired entity; or adjustments to purchase price. We exclude such expenses or benefits as they are related to acquisitions and have no direct correlation to the operation of our on-going business.

Restructuring, impairment charges and valuation changes in equity-owned and debt securities and gains and losses on equity-method investments: we incur restructuring and impairment charges on individual or groups of employed assets and charges and benefits arising from valuation changes in equity-owned and debt securities and gains and losses on equity-method investments, which arise from unforeseen circumstances and/or often occur outside of the ordinary course of our on-going business. Although these events are reflected in our GAAP financials, these unique transactions may limit the comparability of our on-going operations with prior and future periods.

Significant litigation charges or benefits and legal costs: we may incur charges or benefits as well as legal costs in connection with litigation and other contingencies unrelated to our core operations. We exclude these charges or benefits, when significant, as well as legal costs associated with significant legal matters, because we do not believe they are reflective of on-going business and operating results.

Income tax expense: we estimate the tax effect of the excluded items identified above to determine a non-GAAP annual effective tax rate applied to the pretax amount in order to

calculate the non-GAAP provision for income taxes. We also adjust for items for which the nature and/or tax jurisdiction requires the application of a specific tax rate or treatment.

From time to time in the future, there may be other items excluded if we believe that doing so is consistent with the goal of providing useful information to investors and management.

Percentage sales growth in currency neutral amounts are calculated by translating prior period sales in each local currency using the current period’s monthly average foreign exchange rates for that currency and comparing that to current period sales.

There are limitations in using non-GAAP financial measures because the non-GAAP financial measures are not prepared in accordance with generally accepted accounting principles and may be different from non-GAAP financial measures used by other companies. The non-GAAP financial measures are limited in value because they exclude certain items that may have a material impact on our reported financial results. The presentation of this additional information is not meant to be considered in isolation or as a substitute for the directly comparable financial measures prepared in accordance with GAAP in the United States. Investors should review the reconciliation of the non-GAAP financial measures to their most directly comparable GAAP financial measures as provided in the tables accompanying this press release.

Conference Call and Webcast

Management will discuss fourth-quarter and full-year ended December 31, 2021 results in a conference call at 3 PM Pacific Time (6 PM Eastern Time) February 10, 2022. To listen, call 844-200-6205 within the U.S. or 929-526-1599 outside the U.S., Conference ID: 348449. You may also listen to the conference call live via a webcast that is available on the “Investor Relations” section of our website under “Quarterly Results” at

bio-rad.com. The webcast will be available for up to a year.

BIO-RAD and DROPLET DIGITAL PCR are trademarks of Bio-Rad Laboratories, Inc. in certain jurisdictions.

About Bio-Rad

Bio-Rad Laboratories, Inc. (NYSE: BIO and BIOb) is a global leader in developing, manufacturing, and marketing a broad range of innovative products for the life science research and clinical diagnostic markets. With a focus on quality and customer service for 70 years, our products advance the discovery process and improve healthcare. Our customers are university and research institutions, hospitals, public health and commercial laboratories, biotechnology and pharmaceutical companies, as well as applied laboratories that include food safety and environmental quality. Founded in 1952, Bio-Rad is based in Hercules, California, and has a global network of operations with approximately 7,900 employees worldwide. Bio-Rad had revenues of $2.9 billion in 2021. For more information, please visit bio-rad.com.

This release may be deemed to contain certain forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. These forward-looking statements include, without limitation, statements we make regarding estimated future financial performance or results; anticipating non-GAAP currency-neutral revenue growth of approximately 1.0 to 2.0 percent and an estimated non-GAAP operating margin of approximately 19.0 percent for the full year 2022; anticipating another year of progress in 2022 and building on the operating efficiencies we achieved in 2021; and believing that we are well positioned to build on our recent momentum as we continue to return to normalcy and execute our growth strategies. Forward-looking statements generally can be identified by the use of forward-looking terminology such as, "anticipate," "estimate," "believe," "expect," "continue," "will," "project," "assume," "may," "intend," or similar expressions or the negative of those terms or expressions, although not all forward-looking statements contain these words. Such statements involve risks and uncertainties, which could cause actual results to vary materially from those expressed in or indicated by the forward-looking statements. These risks and uncertainties include the duration, severity and impact of the COVID-19 pandemic, global economic conditions, supply chain issues, our ability to develop and market new or improved products, our ability to compete effectively, foreign currency exchange fluctuations, reductions in government funding or capital spending of our customers, international legal and regulatory risks, product quality and liability issues, our ability to integrate acquired companies, products or technologies into our company successfully, changes in the healthcare industry, and natural disasters and other catastrophic events beyond our control. For further information regarding the Company's risks and uncertainties, please refer to the "Risk Factors" and "Management’s Discussion and Analysis of Financial Condition and Results of Operations" in the Company's public reports filed with the Securities and Exchange Commission (the "SEC"), including the Company's Annual Report on Form 10-K for the fiscal year ended December 31, 2020, its Quarterly Report on Form 10-Q for the fiscal quarter ended September 30, 2021, and its Annual Report on Form 10-K for the fiscal year ended December 31, 2021 to be filed with the SEC. The Company cautions you not to place undue reliance on forward-looking statements, which reflect an analysis only and speak only as of the date hereof. Bio-Rad Laboratories, Inc. disclaims any obligation to update these forward-looking statements.

SOURCE: Bio-Rad Laboratories, Inc.

Bio-Rad Laboratories, Inc.

Condensed Consolidated Statements of Income

(In thousands, except per share data)

(Unaudited)

Three Months Ended Year Ended
December 31, December 31,

2021

2020

2021

2020

Net sales

$

732,769

 

$

789,839

 

$

2,922,545

 

$

2,545,626

 

Cost of goods sold

 

331,768

 

 

329,684

 

 

1,281,884

 

 

1,107,804

 

Gross profit

 

401,001

 

 

460,155

 

 

1,640,661

 

 

1,437,822

 

Selling, general and administrative expense

 

224,146

 

 

219,148

 

 

879,574

 

 

800,267

 

Research and development expense

 

69,873

 

 

65,765

 

 

271,657

 

 

226,598

 

Income from operations

 

106,982

 

 

175,242

 

 

489,430

 

 

410,957

 

Interest expense

 

364

 

 

4,703

 

 

1,551

 

 

21,861

 

Foreign currency exchange losses (gains), net

 

2,211

 

 

(707

)

 

2,753

 

 

1,771

 

Change in fair market value of equity and debt securities

 

2,152,505

 

 

(904,316

)

 

(4,926,248

)

 

(4,495,825

)

Other income, net

 

(10,043

)

 

(2,971

)

 

(26,775

)

 

(24,488

)

(Loss) income before income taxes

 

(2,038,055

)

 

1,078,533

 

 

5,438,149

 

 

4,907,638

 

Benefit from (provision for) income taxes

 

464,396

 

 

(239,431

)

 

(1,192,247

)

 

(1,101,371

)

Net (loss) income

$

(1,573,659

)

$

839,102

 

$

4,245,902

 

$

3,806,267

 

Basic (loss) earnings per share:
Net (loss) income per basic share

$

(52.59

)

$

28.13

 

$

142.33

 

$

127.86

 

Weighted average common shares - basic

 

29,922

 

 

29,833

 

 

29,831

 

 

29,768

 

Diluted (loss) earnings per share:
Net (loss) income per diluted share

$

(52.59

)

$

27.81

 

$

140.56

 

$

126.20

 

Weighted average common shares - diluted

 

29,922

 

 

30,170

 

 

30,208

 

 

30,160

 

Note: As a result of the net loss for the three months ended December 31, 2021, all potentially issuable common shares have been excluded from the diluted shares used in the computation of earnings per share as their effect was anti-dilutive.

Bio-Rad Laboratories, Inc.

Condensed Consolidated Balance Sheets

(In thousands)

December 31,
2021

December 31,
2020

(Unaudited)
Current assets:
Cash and cash equivalents

$

470,783

$

662,205

Short-term investments

 

404,695

 

334,473

Accounts receivable, net

 

423,537

 

419,424

Inventories, net

 

572,239

 

622,253

Other current assets

 

117,834

 

101,480

Total current assets

 

1,989,088

 

2,139,835

 
Property, plant and equipment, net

 

490,952

 

491,371

Operating lease right-of-use assets

 

204,798

 

202,136

Goodwill, net

 

347,343

 

291,916

Purchased intangibles, net

 

253,939

 

199,497

Other investments

 

14,387,006

 

9,561,140

Other assets

 

102,669

 

86,723

Total assets

$

17,775,795

$

12,972,618

 
Current liabilities:
Accounts payable, accrued payroll and employee benefits

$

418,927

$

362,326

Current maturities of long-term debt

 

489

 

1,798

Income and other taxes payable

 

46,299

 

57,335

Other current liabilities

 

215,223

 

210,077

Total current liabilities

 

680,938

 

631,536

 
Long-term debt, net of current maturities

 

10,514

 

12,258

Other long-term liabilities

 

3,417,209

 

2,448,884

Total liabilities

 

4,108,661

 

3,092,678

 
Total stockholders' equity

 

13,667,134

 

9,879,940

Total liabilities and stockholders' equity

$

17,775,795

$

12,972,618

Bio-Rad Laboratories, Inc.

Condensed Consolidated Statements of Cash Flows

(In thousands)

(Unaudited)

Year Ended
December 31,

 

2021

2020

 
Cash flows from operating activities:
Cash received from customers

$

2,886,489

 

$

2,531,135

 

Cash paid to suppliers and employees

 

(2,140,882

)

 

(1,886,988

)

Interest paid, net

 

(2,251

)

 

(21,639

)

Income tax payments, net

 

(134,683

)

 

(65,244

)

Other operating activities

 

47,848

 

 

18,064

 

Net cash provided by operating activities

 

656,521

 

 

575,328

 

 
Cash flows from investing activities:
Payments for acquisitions

 

(125,516

)

 

(96,655

)

Other investing activities

 

(658,922

)

 

36,405

 

Net cash used in investing activities

 

(784,438

)

 

(60,250

)

 
Cash flows from financing activities:
Payments on long-term borrowings

 

(3,020

)

 

(426,938

)

Other financing activities

 

(52,409

)

 

(96,103

)

Net cash used in financing activities

 

(55,429

)

 

(523,041

)

 
Effect of foreign exchange rate changes on cash

 

(12,636

)

 

12,427

 

 
Net (decrease) increase in cash, cash equivalents and restricted cash

 

(195,982

)

 

4,464

 

Cash, cash equivalents and restricted cash at beginning of year

 

667,115

 

 

662,651

 

Cash, cash equivalents and restricted cash at end of year

$

471,133

 

$

667,115

 

 
 
Reconciliation of net income to net cash provided by operating activities:
Net income

$

4,245,902

 

$

3,806,267

 

Adjustments to reconcile net income to net cash provided by operating activities:
Depreciation and amortization

 

133,801

 

 

138,127

 

Reduction in the carrying amount of right-of-use assets

 

39,264

 

 

37,071

 

Changes in working capital

 

13,932

 

 

51,678

 

Other

 

(3,776,378

)

 

(3,457,815

)

Net cash provided by operating activities

$

656,521

 

$

575,328

 

Bio-Rad Laboratories, Inc.
Reconciliation of GAAP financial measures to non-GAAP financial measures
(In thousands, except per share data)
(Unaudited)

In addition to the financial measures prepared in accordance with generally accepted accounting principles (GAAP), we use certain non-GAAP financial measures, including non-GAAP net income and non-GAAP diluted income per share (non-GAAP EPS), which exclude amortization of acquisition-related intangible assets; certain acquisition-related expenses and benefits; restructuring charges; asset impairment charges; valuation changes of equity-owned and debt securities; gains and losses on equity-method investments; and significant legal-related charges or benefits and associated legal costs. Non-GAAP net income and non-GAAP EPS also exclude certain other gains and losses that are either isolated or cannot be expected to occur again with any predictability, tax provisions/benefits related to the previous items, and significant discrete tax events. We exclude the above items because they are outside of our normal operations and/or, in certain cases, are difficult to forecast accurately for future periods.

We utilize a number of different financial measures, both GAAP and non-GAAP, in analyzing and assessing the overall performance of our business, in making operating decisions, forecasting and planning for future periods, and determining payments under compensation programs. We consider the use of the non-GAAP measures to be helpful in assessing the performance of the ongoing operation of our business. We believe that disclosing non-GAAP financial measures provides useful supplemental data that, while not a substitute for financial measures prepared in accordance with GAAP, allows for greater transparency in the review of our financial and operational performance. We also believe that disclosing non-GAAP financial measures provides useful information to investors and others in understanding and evaluating our operating results and future prospects in the same manner as management and in comparing financial results across accounting periods and to those of peer companies.

  Three Months Ended     Three Months Ended     Year Ended     Year Ended  
  December 31,   % of   December 31,   % of   December 31,   % of   December 31,   % of
 

2021

  revenue  

2020

  revenue  

2021

  revenue  

2020

  revenue
                 
GAAP net sales  

$

732,769

 

   

$

789,839

 

   

$

2,922,545

 

   

$

2,545,626

 

 
Legal settlements  

 

 

   

 

(31,972

)

   

 

(31,843

)

   

 

(31,972

)

 
Non-GAAP net sales  

$

732,769

 

   

$

757,867

 

   

$

2,890,702

 

   

$

2,513,654

 

 
                 
GAAP cost of goods sold  

$

331,768

 

   

$

329,684

 

   

$

1,281,884

 

   

$

1,107,804

 

 
Amortization of purchased intangibles  

 

(4,659

)

   

 

(4,622

)

   

 

(18,562

)

   

 

(18,322

)

 
Legal settlements  

 

 

   

 

(8,700

)

   

 

(3,535

)

   

 

(8,700

)

 
Restructuring benefits (costs)  

 

112

 

   

 

198

 

   

 

(25,129

)

   

 

1,903

 

 
Other non-recurring items (4)  

 

(274

)

   

 

 

   

 

(274

)

   

 

 

 
Non-GAAP cost of goods sold  

$

326,947

 

   

$

316,560

 

   

$

1,234,384

 

   

$

1,082,685

 

 
                 
GAAP gross profit  

$

401,001

 

 

54.7

%

 

$

460,155

 

 

58.3

%

 

$

1,640,661

 

 

56.1

%

 

$

1,437,822

 

 

56.5

%

Amortization of purchased intangibles  

 

4,659

 

   

 

4,622

 

   

 

18,562

 

   

 

18,322

 

 
Legal settlements  

 

 

   

 

(23,272

)

   

 

(28,308

)

   

 

(23,272

)

 
Restructuring (benefits) costs  

 

(112

)

   

 

(198

)

   

 

25,129

 

   

 

(1,903

)

 
Other non-recurring items (4)  

 

274

 

   

 

 

   

 

274

 

   

 

 

 
Non-GAAP gross profit  

$

405,822

 

 

55.4

%

 

$

441,307

 

 

58.2

%

 

$

1,656,318

 

 

57.3

%

 

$

1,430,969

 

 

56.9

%

                 
GAAP selling, general and administrative expense  

$

224,146

 

   

$

219,148

 

   

$

879,574

 

   

$

800,267

 

 
Amortization of purchased intangibles  

 

(1,839

)

   

 

(2,410

)

   

 

(8,968

)

   

 

(8,967

)

 
Legal matters  

 

(874

)

   

 

(6,313

)

   

 

(16,375

)

   

 

(16,708

)

 
Acquisition related benefits (costs) (1)  

 

 

   

 

3,323

 

   

 

40

 

   

 

4,160

 

 
Restructuring benefits (costs)  

 

1,367

 

   

 

(243

)

   

 

(26,140

)

   

 

(2,235

)

 
Other non-recurring items (4)  

 

(1,635

)

   

 

 

   

 

(1,635

)

   

 

 

 
Non-GAAP selling, general and administrative expense  

$

221,165

 

   

$

213,505

 

   

$

826,496

 

   

$

776,517

 

 
                 
GAAP research and development expense  

$

69,873

 

   

$

65,765

 

   

$

271,657

 

   

$

226,598

 

 
Restructuring benefits (costs)  

 

2,031

 

   

 

139

 

   

 

(13,020

)

   

 

1,253

 

 
Non-GAAP research and development expense  

$

71,904

 

   

$

65,904

 

   

$

258,637

 

   

$

227,851

 

 
                 
GAAP income from operations  

$

106,982

 

 

14.6

%

 

$

175,242

 

 

22.2

%

 

$

489,430

 

 

16.7

%

 

$

410,957

 

 

16.1

%

Legal settlements  

 

 

   

 

(23,272

)

   

 

(28,308

)

   

 

(23,272

)

 
Amortization of purchased intangibles  

 

6,498

 

   

 

7,032

 

   

 

27,530

 

   

 

27,289

 

 
Legal matters  

 

874

 

   

 

6,313

 

   

 

16,375

 

   

 

16,708

 

 
Acquisition related (benefits) costs (1)  

 

 

   

 

(3,323

)

   

 

(40

)

   

 

(4,160

)

 
Restructuring (benefits) costs  

 

(3,510

)

   

 

(94

)

   

 

64,289

 

   

 

(921

)

 
Other non-recurring items (4)  

 

1,909

 

   

 

 

   

 

1,909

 

   

 

 

 
Non-GAAP income from operations  

$

112,753

 

 

15.4

%

 

$

161,898

 

 

21.4

%

 

$

571,185

 

 

19.8

%

 

$

426,601

 

 

17.0

%

                 
GAAP change in fair market value of equity and debt securities  

$

2,152,505

 

   

$

(904,316

)

   

$

(4,926,248

)

   

$

(4,495,825

)

 
Valuation (loss) gain on equity-owned and debt securities  

 

(2,152,505

)

   

 

904,316

 

   

 

4,926,248

 

   

 

4,495,825

 

 
Non-GAAP change in fair market value of equity and debt securities  

$

 

   

$

 

   

$

 

   

$

 

 
                 
GAAP other (income) expense, net  

$

(10,043

)

   

$

(2,971

)

   

$

(26,775

)

   

$

(24,488

)

 
(Loss) gain on equity-method investments  

 

(1,615

)

   

 

(2,072

)

   

 

(7,194

)

   

 

(4,706

)

 
Legal settlements  

 

 

   

 

3,025

 

   

 

311

 

   

 

3,025

 

 
Other non-recurring items (3)  

 

 

   

 

 

   

 

 

   

 

11,680

 

 
Non-GAAP other (income) expense, net  

$

(11,658

)

   

$

(2,018

)

   

$

(33,658

)

   

$

(14,489

)

 
                 
GAAP (loss) income before income taxes  

$

(2,038,055

)

   

$

1,078,533

 

   

$

5,438,149

 

   

$

4,907,638

 

 
Legal settlements  

 

 

   

 

(26,297

)

   

 

(28,619

)

   

 

(26,297

)

 
Amortization of purchased intangibles  

 

6,498

 

   

 

7,032

 

   

 

27,530

 

   

 

27,289

 

 
Legal matters  

 

874

 

   

 

6,313

 

   

 

16,375

 

   

 

16,708

 

 
Acquisition related (benefits) costs (1)  

 

 

   

 

(3,323

)

   

 

(40

)

   

 

(4,160

)

 
Restructuring (benefits) costs  

 

(3,510

)

   

 

(94

)

   

 

64,289

 

   

 

(921

)

 
Valuation loss (gain) on equity-owned and debt securities  

 

2,152,505

 

   

 

(904,316

)

   

 

(4,926,248

)

   

 

(4,495,825

)

 
Loss (gain) on equity-method investments  

 

1,615

 

   

 

2,072

 

   

 

7,194

 

   

 

4,706

 

 
Other non-recurring items (3) (4)  

 

1,909

 

   

 

 

   

 

1,909

 

   

 

(11,680

)

 
Non-GAAP income before income taxes  

$

121,836

 

   

$

159,920

 

   

$

600,539

 

   

$

417,458

 

 
                 
GAAP benefit from (provision for) income taxes  

$

464,396

 

   

$

(239,431

)

   

$

(1,192,247

)

   

$

(1,101,371

)

 
Income tax effect of non-GAAP adjustments (2)  

 

(489,188

)

   

 

200,524

 

   

 

1,064,912

 

   

 

1,001,155

 

 
Non-GAAP provision for income taxes  

$

(24,792

)

   

$

(38,907

)

   

$

(127,335

)

   

$

(100,216

)

 
                 
GAAP net (loss) income  

$

(1,573,659

)

 

-214.8

%

 

$

839,102

 

 

106.2

%

 

$

4,245,902

 

 

145.3

%

 

$

3,806,267

 

 

149.5

%

Legal settlements  

 

 

   

 

(26,297

)

   

 

(28,619

)

   

 

(26,297

)

 
Amortization of purchased intangibles  

 

6,498

 

   

 

7,032

 

   

 

27,530

 

   

 

27,289

 

 
Legal matters  

 

874

 

   

 

6,313

 

   

 

16,375

 

   

 

16,708

 

 
Acquisition related (benefits) costs (1)  

 

 

   

 

(3,323

)

   

 

(40

)

   

 

(4,160

)

 
Restructuring (benefits) costs  

 

(3,510

)

   

 

(94

)

   

 

64,289

 

   

 

(921

)

 
Valuation loss (gain) on equity-owned and debt securities  

 

2,152,505

 

   

 

(904,316

)

   

 

(4,926,248

)

   

 

(4,495,825

)

 
Loss (gain) on equity-method investments  

 

1,615

 

   

 

2,072

 

   

 

7,194

 

   

 

4,706

 

 
Other non-recurring items (3) (4)  

 

1,909

 

   

 

 

   

 

1,909

 

   

 

(11,680

)

 
Income tax effect of non-GAAP adjustments (2)  

 

(489,188

)

   

 

200,524

 

   

 

1,064,912

 

   

 

1,001,155

 

 
Non-GAAP net income  

$

97,044

 

 

13.2

%

 

$

121,013

 

 

16.0

%

 

$

473,204

 

 

16.4

%

 

$

317,242

 

 

12.6

%

                 
GAAP diluted (loss) income per share  

$

(52.59

)

   

$

27.81

 

   

$

140.56

 

   

$

126.20

 

 
Legal settlements  

 

 

   

 

(0.87

)

   

 

(0.95

)

   

 

(0.87

)

 
Amortization of purchased intangibles  

 

0.22

 

   

 

0.23

 

   

 

0.91

 

   

 

0.90

 

 
Legal matters  

 

0.03

 

   

 

0.21

 

   

 

0.54

 

   

 

0.55

 

 
Acquisition related (benefits) costs (1)  

 

 

   

 

(0.11

)

   

 

 

   

 

(0.14

)

 
Restructuring (benefits) costs  

 

(0.12

)

   

 

 

   

 

2.13

 

   

 

(0.03

)

 
Valuation loss (gain) on equity-owned and debt securities  

 

71.24

 

   

 

(29.97

)

   

 

(163.08

)

   

 

(149.07

)

 
Loss (gain) on equity-method investments  

 

0.05

 

   

 

0.07

 

   

 

0.24

 

   

 

0.16

 

 
Other non-recurring items (3) (4)  

 

0.06

 

   

 

 

   

 

0.06

 

   

 

(0.39

)

 
Income tax effect of non-GAAP adjustments (2)  

 

(16.19

)

   

 

6.64

 

   

 

35.25

 

   

 

33.21

 

 
Add back anti-dilutive shares  

 

0.51

 

   

 

 

   

 

 

   

 

 

 
Non-GAAP diluted income per share  

$

3.21

 

   

$

4.01

 

   

$

15.66

 

   

$

10.52

 

 
                 
GAAP diluted weighted average shares used in per share calculation  

 

29,922

 

   

 

30,170

 

   

 

30,208

 

   

 

30,160

 

 
Shares included in non-GAAP net income per share, but excluded from GAAP net loss per share as they would have been anti-dilutive  

 

291

 

   

 

 

   

 

 

   

 

 

 
Non-GAAP diluted weighted average shares used in per share calculation  

 

30,213

 

   

 

30,170

 

   

 

30,208

 

   

 

30,160

 

 
                 
Reconciliation of Net income to adjusted EBITDA:                
GAAP net (loss) income  

$

(1,573,659

)

 

-214.8

%

 

$

839,102

 

 

106.2

%

 

$

4,245,902

 

 

145.3

%

 

$

3,806,267

 

 

149.5

%

Interest expense  

 

364

 

   

 

4,703

 

   

 

1,551

 

   

 

21,861

 

 
(Benefit from) provision for income taxes  

 

(464,396

)

   

 

239,431

 

   

 

1,192,247

 

   

 

1,101,371

 

 
Depreciation and amortization  

 

33,726

 

   

 

36,189

 

   

 

133,801

 

   

 

138,127

 

 
Foreign currency exchange losses (gains), net  

 

2,211

 

   

 

(707

)

   

 

2,753

 

   

 

1,771

 

 
Other income, net  

 

(10,043

)

   

 

(2,971

)

   

 

(26,775

)

   

 

(24,488

)

 
Change in fair market value of equity and debt securities  

 

2,152,505

 

   

 

(904,316

)

   

 

(4,926,248

)

   

 

(4,495,825

)

 
Dividend from Sartorius AG  

 

 

   

 

 

   

 

18,991

 

   

 

8,922

 

 
Legal settlements (5)  

 

 

   

 

(23,272

)

   

 

(28,308

)

   

 

(23,272

)

 
Legal matters  

 

874

 

   

 

6,313

 

   

 

16,375

 

   

 

16,708

 

 
Acquisition related (benefits) costs (1)  

 

 

   

 

(3,323

)

   

 

(40

)

   

 

(4,160

)

 
Restructuring (benefits) costs  

 

(3,510

)

   

 

(94

)

   

 

64,289

 

   

 

(921

)

 
Other non-recurring items (4) (6)  

 

1,909

 

   

 

 

   

 

1,909

 

   

 

 

 
Adjusted EBITDA  

$

139,981

 

 

19.1

%

 

$

191,055

 

 

25.2

%

 

$

696,447

 

 

24.1

%

 

$

546,361

 

 

21.7

%

(1) Release of contingent consideration and other acquisition-related (benefits) expenses.
(2) Excluded items identified in the reconciliation schedule are tax effected by application of a non-GAAP effective tax rate. The non-GAAP tax provision is adjusted for items, the nature of which and/or tax jurisdiction requires the application of a specific tax rate or treatment.
(3) Gain on the sale of a division (2020).
(4) Incremental costs to comply with the European Union's In Vitro Diagnostics Regulation ("IVDR") for previously approved products (2021).
(5) Amount excludes interest income received in connection with legal settlements.
(6) Amount excludes gain on the sale of a division in 2020.

2022 Financial Outlook

Forecasted non-GAAP operating margin excludes 86 basis points related to amortization of purchased intangibles. Forecasted non-GAAP operating margin does not reflect future gains and charges that are inherently difficult to predict and estimate due to their unknown timing, effect and/or significance, such as foreign currency fluctuations, future gains or losses associated with certain legal matters, acquisitions and restructuring activities.

Edward Chung, Vice President, Investor Relations

510-741-6104

ir@bio-rad.com

Source: Bio-Rad Laboratories, Inc.

FAQ

What were Bio-Rad's Q4 2021 earnings results?

Bio-Rad reported Q4 2021 net sales of $732.8 million, with a net loss of $1,573.7 million, or $52.59 per diluted share.

How did Bio-Rad's Clinical Diagnostics performance compare in Q4 2021?

In Q4 2021, Clinical Diagnostics segment net sales rose 12.6% compared to the same quarter in 2020.

What is the outlook for Bio-Rad in 2022?

Bio-Rad anticipates non-GAAP currency-neutral revenue growth of approximately 1.0 to 2.0 percent for 2022.

Bio-Rad Laboratories, Inc.

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