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Nucleus RadioPharma Secures Series A Extension Funding with AstraZeneca Investment

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Nucleus RadioPharma announced the closing of a Series A extension funding round with AstraZeneca as a new investor. The funding aims to expand Nucleus's development, supply, and commercial manufacturing capabilities for targeted radiotherapies and theranostics, improving global patient access. Dr. Tyrell Rivers, Executive Director of Corporate Ventures at AstraZeneca, joined Nucleus’s Board of Directors. The precision of theranostics, combining diagnostics and therapeutics through radiotracers, offers a promising treatment for metastatic cancers, minimizing side effects compared to traditional methods. Charles S. Conroy, CEO of Nucleus, highlighted the remarkable effectiveness and safety of these drugs. The funding will facilitate large-scale production, addressing the challenges of the perishable nature of radiopharmaceuticals and enhancing their accessibility for cancer treatment worldwide.

Positive
  • Series A extension funding secured with AstraZeneca as a new investor.
  • Expansion of development, supply, and commercial manufacturing capabilities.
  • Dr. Tyrell Rivers appointed to the Board of Directors, bringing extensive experience.
  • Funding aims to improve global access to targeted radiotherapies and theranostics.
  • Theranostics showing promise in treating metastatic cancers with reduced side effects.
Negative
  • Challenges in managing the supply chain for radiopharmaceuticals due to their perishable nature.

Insights

The recent Series A extension funding secured by Nucleus RadioPharma, with AstraZeneca as a new investor, indicates a strong vote of confidence from a leading pharmaceutical company. Financially, this investment provides Nucleus with additional capital to expand its development, supply and manufacturing capabilities. This capital infusion is essential to support the scalability required for mass production of theranostic radiopharmaceuticals. The involvement of other high-profile investors such as GE Healthcare and Mayo Clinic further solidifies the financial stability and growth potential of Nucleus RadioPharma.

From a financial perspective, this infusion of funds can accelerate the company's timelines, reduce operational risks and potentially lead to earlier profitability. The collaboration with top-tier investors could also facilitate future funding rounds and partnerships. For retail investors, this indicates a lower financial risk and higher potential return on investment in the long run.

The expansion of Nucleus RadioPharma’s capabilities in theranostics and targeted radiotherapies is a important development in the field of personalized cancer treatment. Theranostics, which combine diagnostics and therapeutics, represent a significant advancement in oncology, offering precise targeting of cancer cells while minimizing damage to healthy tissue.

The funding will enable the company to scale up the production of these advanced treatments, making them more accessible to patients. This is particularly important for metastatic cancers such as neuroendocrine tumors and prostate cancer, where traditional treatments often fall short. The entry of AstraZeneca, a key player in the pharmaceutical industry, adds credibility and significance to Nucleus’s innovative approaches. The extended funding not only supports production but also aligns with the broader industry trend toward precision medicine.

The market for theranostics is one of the fastest-growing segments within oncology, driven by the need for more effective and personalized treatments. With the involvement of AstraZeneca and other notable investors, Nucleus RadioPharma is well-positioned to capture a significant share of this market.

Radiopharmaceuticals face unique logistical challenges due to the perishable nature of radioactive materials. Nucleus’s focus on enhancing manufacturing and supply chain efficiency is a vital step towards addressing these challenges. This not only enhances accessibility but also ensures that the treatments reach patients in a timely manner. The company’s integrated approach positions it uniquely in the market, setting it apart from competitors who may lack such comprehensive capabilities. For investors, this means Nucleus has a distinct competitive advantage that could translate into significant market share.

Dr. Tyrell Rivers joins the Nucleus Board of Directors

ROCHESTER, Minn.--(BUSINESS WIRE)-- Nucleus RadioPharma, the world’s first fully integrated development, manufacturing, and supply chain organization for radiopharmaceuticals, today announced the closing of a Series A extension round with new investor AstraZeneca (LSE/STO/Nasdaq: AZN). AstraZeneca joins existing investors from GE Healthcare, Mayo Clinic, Eclipse Ventures, Fox Chase Cancer Center, Echo Global Granger Management Mercy Health, and the University of Missouri as Nucleus expands development, supply, and commercial manufacturing capabilities to make targeted radiotherapies and theranostics more accessible to patients globally. Concurrent with the financing, Tyrell Rivers, PhD, Executive Director of Corporate Ventures at AstraZeneca, was named to the Board of Directors.

Theranostics combines diagnostics and therapeutics for personalized cancer treatment using radiotracers that selectively bind to specific cancer cells. A low-dose radiotracer helps visualize tumors, guiding targeted therapy, while a higher-dose radiotracer delivers potent radiation to kill cancer cells with minimal damage to healthy tissues. This precision approach reduces side effects compared to traditional treatments and shows promise in treating metastatic cancers like neuroendocrine tumors, prostate cancer, and lymphoma.

“Theranostic radiopharmaceuticals represent a new hope for millions of people with limited treatment alternatives,” said Nucleus RadioPharma CEO Charles S. Conroy. “These drugs, designed for precise targeting, are demonstrating remarkable effectiveness while upholding an exceptional safety record. The funding expands the accessibility and impact of these life-saving treatments, paving the way for large-scale production and instilling optimism in those with limited options.”

Dr. Tyrell Rivers is Executive Director of Corporate Ventures at AstraZeneca, where he is responsible for creating and executing innovative, value-enhancing business strategies. Prior to assuming this role in 2014, he worked at MedImmune Ventures, specializing in life science investing. Earlier in his career, Dr. Rivers held various positions at Merck & Co., where he led technical support for commercial vaccines and directed global business initiatives for accessing key technologies for research and development. He is a Board member of ADC Therapeutics, Cellectis, Cerapedics, and Quell Therapeutics. Dr. Rivers holds his B.S. in Chemical Engineering from the Massachusetts Institute of Technology, a Ph.D. in Chemical Engineering from the University of Texas at Austin, and an M.B.A. from the New York University Stern School of Business.

With more than 20 years of supporting business initiatives in the investment and life science sectors, Dr. Rivers brings extensive experience in aiding company growth, directing corporate strategy, and establishing financially sound businesses.

Conroy added: “The support of AstraZeneca and Tyrell on the board has ignited our excitement as this funding will facilitate the expansion of our development, supply, and commercial manufacturing capabilities, ultimately enhancing global accessibility to targeted radiotherapies and theranostics for patients worldwide.”

Radiopharmaceuticals offer precise cancer treatment, but the intricate supply chain, akin to managing a rapidly melting ice cube, demands precise timing due to the perishable nature of radioactive materials, consequently restricting patient access. Nucleus RadioPharma is at the forefront of addressing these challenges by enhancing manufacturing and supply chain efficiency, to broaden the accessibility of radiopharmaceuticals as a promising frontier in oncology.

About Nucleus RadioPharma

Nucleus RadioPharma is an innovative CDMO in the radiopharmaceutical industry, dedicated to the development and manufacturing of targeted radiotherapies. With an emphasis on innovation and quality, the company provides an array of services, from formulation and analytical development to regulatory documentation and drug product manufacturing. Nucleus RadioPharma’s technology platforms are at the forefront of radiopharmaceutical research, designed to advance new therapies through clinical trials to commercialization. Recognized for its flexible approach, the company offers multiple onboarding points to accommodate innovators at various stages of their product lifecycle. Backed by Eclipse, GE HealthCare, Echo Global, Fox Chase Cancer Center, Granger Management, Mayo Clinic, Mercy Health, and University of Missouri, Nucleus RadioPharma stands well-supported by leading institutions and organizations committed to advancing healthcare through innovative solutions. Please visit nucleusrad.com and follow us on LinkedIn for more information.

Patrick Schmidt

630-290-2787

nucleusrad@consortpartners.com

Source: Nucleus RadioPharma

FAQ

What recent funding did Nucleus RadioPharma secure involving AstraZeneca?

Nucleus RadioPharma secured Series A extension funding with AstraZeneca as a new investor.

What is the significance of the new funding for Nucleus RadioPharma?

The new funding will expand Nucleus's development, supply, and commercial manufacturing capabilities for targeted radiotherapies and theranostics, enhancing global patient access.

Who is the new board member from AstraZeneca at Nucleus RadioPharma?

Dr. Tyrell Rivers, Executive Director of Corporate Ventures at AstraZeneca, joined the Board of Directors of Nucleus RadioPharma.

What are theranostics?

Theranostics combine diagnostics and therapeutics for personalized cancer treatment using radiotracers that selectively bind to specific cancer cells, minimizing damage to healthy tissues.

How do theranostics benefit cancer treatment?

Theranostics offer precise targeting of cancer cells, reduce side effects compared to traditional treatments, and show promise in treating metastatic cancers like neuroendocrine tumors, prostate cancer, and lymphoma.

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