STOCK TITAN

Apollomics Inc. Warrant - APLMW STOCK NEWS

Welcome to our dedicated page for Apollomics Warrant news (Ticker: APLMW), a resource for investors and traders seeking the latest updates and insights on Apollomics Warrant stock.

Apollomics Inc is a clinical-stage biopharmaceutical company dedicated to developing oncology therapies that can be combined with other treatments to target the immune system and molecular pathways for cancer treatment. Their lead programs, vebreltinib (APL-101) and uproleselan (APL-106), show promising results in treating various cancers.

Rhea-AI Summary

Apollomics (NASDAQ: APLM) announced disappointing top-line results from its Phase 3 bridging trial of uproleselan in China for relapsed or refractory acute myeloid leukemia patients. The trial, which enrolled 140 subjects randomized 1:1, failed to demonstrate favorable benefits when comparing uproleselan plus chemotherapy versus chemotherapy alone.

The median overall survival in the uproleselan arm was 9.3 months versus 14.3 months in the chemotherapy-only arm. While the drug was generally well-tolerated, serious adverse events occurred in 43% of uproleselan patients compared to 39% in the control group. Following these results and a previous failed global Phase 3 trial by partner Glycomimetics, Apollomics is concluding the program with expected remaining expenses under $500,000.

Rhea-AI Impact
Rhea-AI Sentiment
End-of-Day
16.82%
Tags
-
Rhea-AI Summary

Apollomics (Nasdaq: APLM) has successfully regained compliance with Nasdaq's minimum bid price requirement. The company received confirmation on December 10, 2024, that its Class A Ordinary Shares maintained a closing bid price of $1.00 or higher for ten consecutive business days from November 25 to December 9, 2024. This development ensures the continued listing of Apollomics' shares on the Nasdaq Capital Market under the symbol 'APLM'. The matter is now considered closed.

Rhea-AI Impact
Rhea-AI Sentiment
End-of-Day
6.38%
Tags
none
-
Rhea-AI Summary

Apollomics (Nasdaq: APLM) announced a 1-for-100 reverse share split of its class A ordinary shares, effective November 25, 2024. The split was approved by shareholders at the Extraordinary General Meeting on November 14, 2024. The company's shares will continue trading under 'APLM' with a new CUSIP number G0411D123. The authorized share capital will increase to 130,000,000 shares. As part of the split, warrant exercise prices will be adjusted, with public warrants' exercise price increasing to $1,150.00 from $11.50. No fractional shares will be issued.

Rhea-AI Impact
Rhea-AI Sentiment
End-of-Day
-1%
Tags
Rhea-AI Summary

Apollomics Inc. (Nasdaq: APLM) presented data on vebreltinib for non-small cell lung cancer (NSCLC) with METex14 skipping mutations at the ESMO Congress 2024. Key findings include:

1. Efficacy in both treatment-naïve and previously treated patients:
- Treatment-naïve: 66.7% overall response rate (ORR), 17.3 months median duration of response (DOR), 13.8 months median progression-free survival (PFS)
- Previously treated: 61.1% ORR, 16.7 months median DOR, 7.4 months median PFS

2. Efficacy regardless of MET gene copy number (GCN):
- GCN<4: 67.8% ORR
- GCN<6: 69.2% ORR
- GCN>4: 100% ORR (5/5 patients)

3. Safety profile: 48.1% of patients experienced grade 3 or higher treatment-related adverse events, with edema being most common (16.7%). No deaths were reported due to treatment-emergent adverse events.

Rhea-AI Impact
Rhea-AI Sentiment
End-of-Day
-11.11%
Tags
none
-
Rhea-AI Summary

Apollomics Inc. (Nasdaq: APLM), a late-stage clinical biopharmaceutical company, has announced its participation in the H.C. Wainwright 26th Annual Global Investment Conference. The event will take place from September 9-11, 2024, both virtually and in-person at the Lotte New York Palace Hotel in New York, NY.

Key details of Apollomics' participation include:

  • An on-demand company presentation available from September 9, 2024, at 7:00 am ET
  • Presenters: Guo-Liang Yu, PhD (Chairman and CEO) and Matthew Plunkett, PhD (CFO)
  • Management will be available for virtual one-on-one meetings
  • The presentation will be accessible on the company's website

Apollomics focuses on developing oncology drug candidates for difficult-to-treat and treatment-resistant cancers.

Rhea-AI Impact
Rhea-AI Sentiment
End-of-Day
-61.15%
Tags
conferences
-
Rhea-AI Summary

Apollomics Inc. (Nasdaq: APLM) reported its first half 2024 financial results and clinical progress for vebreltinib. Key highlights include:

1. Promising preliminary results from the vebreltinib program for tumors with Met dysregulation, including non-CNS MET fusion tumors and NSCLC with MET amplification.

2. Cash position of $25.9 million as of June 30, 2024, with runway into Q3 2025.

3. R&D expenses of $16.9 million and G&A expenses of $10.2 million for H1 2024.

4. Net loss of $(35.2) million, or $(0.38) per share, including a $10 million impairment loss for uproleselan.

5. Strategic focus on vebreltinib for NSCLC patients with Met Amplification.

6. Raised $5.8 million in a PIPE financing in May 2024.

Rhea-AI Impact
Rhea-AI Sentiment
End-of-Day
-- %
Tags
Rhea-AI Summary

Apollomics Inc. (Nasdaq: APLM) announced positive preliminary data from its Phase 2 SPARTA trial of vebreltinib in patients with non-CNS MET fusion solid tumors. The study showed a 43% overall response rate, with six confirmed responses out of 14 patients. Key highlights include:

- One complete response in metastatic non-small cell lung cancer (NSCLC)
- Five partial responses across NSCLC, pancreatic cancer, and intrahepatic bile duct cancer
- Median overall survival of 12.4 months
- Median progression-free survival of 4.5 months
- Median duration of response of 5.6 months
- Longest ongoing response of 18 months

The company believes these results support vebreltinib's potential as a targeted therapy for tumors with MET alterations, which occur in 0.1-0.3% of solid tumors.

Rhea-AI Impact
Rhea-AI Sentiment
End-of-Day
-- %
Tags
-
Rhea-AI Summary

Apollomics Inc. (Nasdaq: APLM), a late-stage clinical biopharmaceutical company focusing on oncology drug candidates for difficult-to-treat and treatment-resistant cancers, has announced its participation in the Canaccord Genuity 44th Annual Growth Conference. The event is scheduled for August 13-15, 2024, in Boston, MA.

Key details of Apollomics' presentation:

  • Date and Time: Tuesday, August 14, 2024, at 9:30 am ET
  • Location: InterContinental Boston Hotel
  • Presenter: Matthew Plunkett, PhD, Chief Financial Officer

The company management will be available for one-on-one meetings during the conference. Interested investors can contact their Canaccord Genuity representative to schedule meetings. A webcast link for the presentation will be available on the company's website under the Investors section on the Events page.

Rhea-AI Impact
Rhea-AI Sentiment
End-of-Day
-- %
Tags
conferences
-
Rhea-AI Summary

Apollomics Inc. (Nasdaq: APLM), a late-stage clinical biopharmaceutical company, has been granted a 180-day extension by Nasdaq to regain compliance with the minimum bid price requirement. The company now has until January 13, 2025 to meet the $1.00 per share minimum bid price for its Ordinary Shares. This extension follows a previous notice of non-compliance received on January 16, 2024.

To regain compliance, Apollomics must maintain a closing bid price of at least $1.00 per share for a minimum of ten consecutive business days before the deadline. If unsuccessful, the company may face delisting, with an option to appeal to a Nasdaq Hearings Panel. Apollomics is actively monitoring its stock price and exploring options to meet the requirement, though success is not guaranteed.

Rhea-AI Impact
Rhea-AI Sentiment
End-of-Day
-- %
Tags
none
Rhea-AI Summary

Apollomics (Nasdaq: APLM) announced a revised strategic focus on the clinical development of vebreltinib for NSCLC patients with Met Amplification mutations and significant changes in its executive leadership. The SPARTA Phase 2 trial will concentrate on this high-need patient population. Co-founder and President Sanjeev Redkar, Ph.D., and Chief Medical Officer Peony Yu, M.D., will transition to consulting roles in August. These changes are part of a broader cost-reduction strategy expected to cut operating expenses by over 50% and extend funding until Q3 2025.

Apollomics aims to generate additional clinical data to support regulatory submissions, with updates anticipated in 2024 and 2025. The departures of key executives are aligned with the company's resource needs and focus on maximizing the efficient use of capital.

Rhea-AI Impact
Rhea-AI Sentiment
End-of-Day
-- %
Tags
management

FAQ

What is the current stock price of Apollomics Warrant (APLMW)?

The current stock price of Apollomics Warrant (APLMW) is $0.0125 as of December 20, 2024.

What is the market cap of Apollomics Warrant (APLMW)?

The market cap of Apollomics Warrant (APLMW) is approximately 27.9M.

What is Apollomics Inc focused on?

Apollomics Inc focuses on developing oncology therapies that target the immune system and molecular pathways for cancer treatment.

What are Apollomics Inc lead programs?

Apollomics Inc lead programs include vebreltinib (APL-101) and uproleselan (APL-106) which show promising results in treating various cancers.

What is vebreltinib (APL-101) used for?

vebreltinib (APL-101) is a potent, selective c-Met inhibitor used in the treatment of non-small cell lung cancer and other advanced tumors with c-Met alterations.

What is uproleselan (APL-106)?

uproleselan (APL-106) is a specific E-Selectin antagonist that could be used adjunctively with standard chemotherapy to treat acute myeloid leukemia.

How effective is vebreltinib in treating different tumor types?

Preclinical studies have shown that vebreltinib is effective for a variety of tumor types carrying MET-driver alterations.

What do Phase 2 and 2/3 trials demonstrate about vebreltinib?

Data from Phase 2 and 2/3 trials demonstrate continued efficacy and safety of vebreltinib for treating different tumor types carrying MET-driver alterations.

How can I contact Apollomics Inc for Investor Relations?

For Investor Relations, you can contact Peter Vozzo at ICR Westwicke by email at Peter.Vozzo@westwicke.com or phone at +1-443-213-0505.

How can I contact Apollomics Inc for Media Relations?

For Media Relations, you can contact Sean Leous at ICR Westwicke by email at Sean.Leous@westwicke.com or phone at +1-646-866-4012.

Apollomics Inc. Warrant

Nasdaq:APLMW

APLMW Rankings

APLMW Stock Data

27.88M
109.97M
United States of America