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Alnylam to Host Ninth Annual “RNAi Roundtable” Webcast Series

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Alnylam Pharmaceuticals has announced its 9th annual 'RNAi Roundtable' webinar series starting September 27, 2022. This series will feature discussions on pipeline programs, RNAi platform innovations, and clinical developments. Key sessions include:

  • Cemdisiran for IgA Nephropathy - September 27, 2022
  • Leadership in RNAi - October 21, 2022
  • CNS Delivery for Alzheimer’s - November 1, 2022

A virtual R&D Day is scheduled for December 15, 2022, focusing on RNAi pipeline advancements. More details are available on their website.

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– Series Will Culminate in a Virtual R&D Day on December 15, 2022

CAMBRIDGE, Mass.--(BUSINESS WIRE)-- Alnylam Pharmaceuticals, Inc. (Nasdaq: ALNY), the leading RNAi therapeutics company, announced today that it plans to host its 9th annual series of “RNAi Roundtable” webinars over the coming weeks. The series will offer presentations from Alnylam scientists and program leaders who will review recent progress in a selection of the Company’s pipeline programs and platform innovations, as well as medical thought leaders who will provide their perspectives on clinical developments and unmet needs. Each event will be webcast live on the Investors section of the Company’s website at investors.alnylam.com/events, and a replay will be posted on the Alnylam website approximately three hours after each event.

The 2022 RNAi Roundtable schedule is as follows:

  • Cemdisiran, in Development for the Treatment of IgA Nephropathy (IgAN) and Other Complement-Mediated Diseases
    Tuesday, September 27, 10:00 am ET
  • Alnylam Engine for Sustainable Innovation: Leadership in RNAi Platform and Human Genetics
    Friday, October 21, 10:00 am ET
  • CNS Delivery and ALN-APP, in Development for the Treatment of Alzheimer’s Disease and Cerebral Amyloid Angiopathy
    Tuesday, November 1, 11:00 am ET

Please visit the Capella section of our website for the latest information regarding webcast dates.

The Company also announced today that it plans to host a virtual R&D Day event on the morning of Thursday, December 15, 2022. Alnylam management will be joined by external guest speakers for a review of the Company’s RNAi pipeline and platform activities, including advancements in its TTR franchise programs. Additional details to follow.

About RNAi

RNAi (RNA interference) is a natural cellular process of gene silencing that represents one of the most promising and rapidly advancing frontiers in biology and drug development today. Its discovery has been heralded as “a major scientific breakthrough that happens once every decade or so,” and was recognized with the award of the 2006 Nobel Prize for Physiology or Medicine. By harnessing the natural biological process of RNAi occurring in our cells, a new class of medicines known as RNAi therapeutics is now a reality. Small interfering RNA (siRNA), the molecules that mediate RNAi and comprise Alnylam's RNAi therapeutic platform, function upstream of today’s medicines by potently silencing messenger RNA (mRNA) – the genetic precursors – that encode for disease-causing or disease pathway proteins, thus preventing them from being made. This is a revolutionary approach with the potential to transform the care of patients with genetic and other diseases.

About Alnylam Pharmaceuticals

Alnylam (Nasdaq: ALNY) has led the translation of RNA interference (RNAi) into a whole new class of innovative medicines with the potential to transform the lives of people afflicted with rare and prevalent diseases with unmet need. Based on Nobel Prize-winning science, RNAi therapeutics represent a powerful, clinically validated approach yielding transformative medicines. Since its founding 20 years ago, Alnylam has led the RNAi Revolution and continues to deliver on a bold vision to turn scientific possibility into reality. Alnylam’s commercial RNAi therapeutic products are ONPATTRO® (patisiran), GIVLAARI® (givosiran), OXLUMO® (lumasiran), AMVUTTRA® (vutrisiran), and Leqvio® (inclisiran) being developed and commercialized by Alnylam’s partner, Novartis. Alnylam has a deep pipeline of investigational medicines, including multiple product candidates that are in late-stage development. Alnylam is executing on its “Alnylam P5x25” strategy to deliver transformative medicines in both rare and common diseases benefiting patients around the world through sustainable innovation and exceptional financial performance, resulting in a leading biotech profile. Alnylam is headquartered in Cambridge, MA. For more information about our people, science and pipeline, please visit www.alnylam.com and engage with us on Twitter at @Alnylam, on LinkedIn, or on Instagram.

Alnylam Pharmaceuticals, Inc.

Christine Regan Lindenboom

(Investors and Media)

617-682-4340

Josh Brodsky

(Investors)

617-551-8276

Source: Alnylam Pharmaceuticals, Inc.

FAQ

What is the purpose of Alnylam's RNAi Roundtable series?

The RNAi Roundtable series aims to present recent progress in Alnylam's pipeline programs and RNAi platform innovations, featuring insights from both internal scientists and external medical thought leaders.

When will Alnylam host its virtual R&D Day?

Alnylam's virtual R&D Day is scheduled for December 15, 2022, focusing on updates regarding their RNAi pipeline and platform activities.

What key topics will be covered during the RNAi Roundtable webinars?

The webinars will discuss topics such as Cemdisiran for IgA Nephropathy, the Alnylam Engine for Sustainable Innovation, and CNS Delivery for Alzheimer's Disease.

Where can I find information about Alnylam's webinar schedule?

Information regarding the RNAi Roundtable webinar schedule can be found on Alnylam's Investors website at investors.alnylam.com/events.

What is RNAi and why is it important to Alnylam?

RNAi, or RNA interference, is a biological process used in drug development that allows for gene silencing. Alnylam harnesses this process to develop innovative RNAi therapeutics for rare and prevalent diseases.

Alnylam Pharmaceuticals, Inc.

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