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Adaptive Biotechnologies Reports First Quarter 2020 Financial Results

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Adaptive Biotechnologies (Nasdaq: ADPT) reported strong financial results for Q1 2020, with revenues reaching $20.9 million, a 65% increase year-over-year. Notably, clinical tests for clonoSEQ surged 75% to 3,518 tests. The company expanded its partnership with Microsoft to tackle COVID-19 diagnostics and formed a strategic alliance with Amgen for therapeutic antibody development. However, operating expenses rose to $55.5 million, leading to a net loss of $31.4 million. Due to COVID-19 uncertainty, the company withdrew its annual revenue guidance for 2020.

Positive
  • Revenue of $20.9 million for Q1 2020, a 65% increase year-over-year.
  • Clinical tests for clonoSEQ increased 75% to 3,518 tests.
  • Sequencing revenue rose to $9.5 million, a 56% increase.
  • Development revenue increased to $11.4 million, up 74%.
Negative
  • Operating expenses increased to $55.5 million, a 70% rise from the prior year.
  • Net loss was $31.4 million, compared to $18.4 million in Q1 2019.
  • Withdrew annual revenue guidance for 2020 due to COVID-19 impact.

SEATTLE, May 12, 2020 (GLOBE NEWSWIRE) -- Adaptive Biotechnologies Corporation (“Adaptive Biotechnologies”) (Nasdaq: ADPT), a commercial stage biotechnology company that aims to translate the genetics of the adaptive immune system into clinical products to diagnose and treat disease, today reported financial results for the quarter ended March 31, 2020.

“Adaptive’s immune medicine platform was built to decode the specific immune response to any disease, which we are now applying in full force to COVID-19,” said Chad Robins, chief executive officer and co-founder of Adaptive Biotechnologies. “Importantly, we are able to do this while maintaining focus on our current products and future pipeline.”

Recent Highlights

  • Revenue of $20.9 million for the first quarter of 2020, representing a 65% increase over the corresponding period in 2019
  • Clinical tests for clonoSEQ increased 75% to 3,518 clinical tests in the first quarter of 2020, compared to the first quarter 2019
  • Extended existing partnership with Microsoft to decode the adaptive immune response to COVID-19 and potentially develop an improved diagnostic; data to be made publicly available
  • Announced strategic partnership with Amgen to leverage Adaptive’s immune medicine platform to discover and develop therapeutic antibodies for COVID-19
  • Executed South San Francisco lease expansion to construct personalized cell therapy prototyping lab for Genentech collaboration

First Quarter 2020 Financial Results

Revenue was $20.9 million for the quarter ended March 31, 2020, representing a 65% increase from the first quarter in the prior year. Sequencing revenue was $9.5 million for the quarter, representing a 56% increase from the first quarter in the prior year. Development revenue increased to $11.4 million for the quarter, representing a 74% increase from the first quarter in the prior year.

Operating expenses were $55.5 million for the first quarter of 2020, compared to $32.7 million in the first quarter of the prior year, representing an increase of 70%.

Net loss was $31.4 million for the first quarter of 2020, compared to $18.4 million for the same period in 2019.

Adjusted EBITDA (non-GAAP) was a loss of $28.0 million for the first quarter of 2020, compared to a loss of $15.2 million for the first quarter of the prior year.

Cash, cash equivalents and marketable securities was $655.8 million as of March 31, 2020.

2020 Financial Guidance

Given the ongoing uncertainty of the scope, duration and impact of the COVID-19 pandemic, Adaptive Biotechnologies is withdrawing its previously announced annual revenue guidance for 2020, which was issued on February 26, 2020.

Webcast and Conference Call Information

Adaptive Biotechnologies will host a conference call to discuss its first quarter financial results after market close on Tuesday, May 12, 2020 at 4:30 PM Eastern Time. The conference call can be accessed at http://investors.adaptivebiotech.com. The webcast will be archived and available for replay at least 90 days after the event.

About Adaptive Biotechnologies

Adaptive Biotechnologies (“we” or “our”) is a commercial-stage biotechnology company focused on harnessing the inherent biology of the adaptive immune system to transform the diagnosis and treatment of disease. We believe the adaptive immune system is nature’s most finely tuned diagnostic and therapeutic for most diseases, but the inability to decode it has prevented the medical community from fully leveraging its capabilities. Our proprietary immune medicine platform reveals and translates the massive genetics of the adaptive immune system with scale, precision and speed to develop products in life sciences research, clinical diagnostics and drug discovery. We have two commercial products, and a robust clinical pipeline to diagnose, monitor and enable the treatment of diseases such as cancer, autoimmune conditions and infectious diseases. Our goal is to develop and commercialize immune-driven clinical products tailored to each individual patient. For more information, please visit adaptivebiotech.com.       

Forward-Looking Statements

This press release contains forward-looking statements that are based on management’s beliefs and assumptions and on information currently available to management. All statements contained in this release other than statements of historical fact are forward-looking statements, including statements regarding our ability to develop, commercialize and achieve market acceptance of our current and planned products and services, our research and development efforts, and other matters regarding our business strategies, use of capital, results of operations and financial position, and plans and objectives for future operations. 

In some cases, you can identify forward-looking statements by the words “may,” “will,” “could,” “would,” “should,” “expect,” “intend,” “plan,” “anticipate,” “believe,” “estimate,” “predict,” “project,” “potential,” “continue,” “ongoing” or the negative of these terms or other comparable terminology, although not all forward-looking statements contain these words. These statements involve risks, uncertainties and other factors that may cause actual results, levels of activity, performance or achievements to be materially different from the information expressed or implied by these forward-looking statements. These risks, uncertainties and other factors are described under "Risk Factors," "Management's Discussion and Analysis of Financial Condition and Results of Operations" and elsewhere in the documents we file with the Securities and Exchange Commission from time to time. We caution you that forward-looking statements are based on a combination of facts and factors currently known by us and our projections of the future, about which we cannot be certain. As a result, the forward-looking statements may not prove to be accurate. The forward-looking statements in this press release represent our views as of the date hereof. We undertake no obligation to update any forward-looking statements for any reason, except as required by law.

Use of Non-GAAP Financial Measure

This press release includes references to Adjusted EBITDA, which is a non-GAAP financial measure that we define as net loss adjusted for interest and other income, net, income tax benefit (expense), depreciation and amortization and share-based compensation expenses. We have provided a reconciliation of net loss, the most directly comparable GAAP financial measure, to Adjusted EBITDA at the end of this press release.

Management uses Adjusted EBITDA to evaluate the financial performance of our business and the effectiveness of our business strategies. We present Adjusted EBITDA because we believe it is frequently used by analysts, investors and other interested parties to evaluate companies in our industry and it facilitates comparisons on a consistent basis across reporting periods. Further, we believe it is helpful in highlighting trends in our operating results because it excludes items that are not indicative of our core operating performance.

Adjusted EBITDA has limitations as an analytical tool and you should not consider it in isolation, or as a substitute for analysis of our results as reported under GAAP. We may in the future incur expenses similar to the adjustments in the presentation of Adjusted EBITDA. In particular, we expect to incur meaningful share-based compensation expense in the future. Other limitations include that Adjusted EBITDA does not reflect:

  • all expenditures or future requirements for capital expenditures or contractual commitments;
  • changes in our working capital needs;
  • income tax benefit (expense), which may be a necessary element of our costs and ability to operate;
  • the costs of replacing the assets being depreciated and amortized, which will often have to be replaced in the future;
  • the non-cash component of employee compensation expense; and
  • the impact of earnings or charges resulting from matters we consider not to be reflective, on a recurring basis, of our ongoing operations.

In addition, Adjusted EBITDA may not be comparable to similarly titled measures used by other companies in our industry or across different industries.

Investor Contact

Carrie Mendivil
investors@adaptivebiotech.com

Media Contact

Beth Keshishian
media@adaptivebiotech.com


Adaptive Biotechnologies
Condensed Statements of Operations
(in thousands, except share and per share amounts)
(unaudited)

100%; border-collapse:collapse !important;">
 Three Months Ended March 31,
65%; width:65%; min-width:65%;"> 1%; width:1%; min-width:1%;"> 15%; width:15%; min-width:15%;">20201%; width:1%; min-width:1%;"> 1%; width:1%; min-width:1%;"> 1%; width:1%; min-width:1%;"> 15%; width:15%; min-width:15%;">20191%; width:1%; min-width:1%;"> 
Revenue   
Sequencing revenue$   9,469  $   6,083 
Development revenue   11,441     6,583 
Total revenue   20,910     12,666 
Operating expenses   
Cost of revenue   5,343     4,988 
Research and development   23,935     12,483 
Sales and marketing   14,007     7,817 
General and administrative   11,821     7,004 
Amortization of intangible assets   424     419 
Total operating expenses   55,530     32,711 
Loss from operations   (34,620)    (20,045)
Interest and other income, net   2,894      1,659 
Income tax benefit   323     — 
Net loss   (31,403)    (18,386)
Fair value adjustment to Series E-1 convertible preferred stock options   —      (254)
Net loss attributable to common shareholders$  (31,403) $  (18,640)
Net loss per share attributable to common shareholders, basic and diluted$   (0.25) $  (1.45)
Weighted-average shares used in computing net loss per share attributable to common shareholders, basic and diluted   126,058,389     12,886,087 

Adaptive Biotechnologies
Condensed Balance Sheets
(in thousands, except share and per share amounts)

100%; border-collapse:collapse !important;">

 
  
  March 31,
2020
 December 31,
2019
  (unaudited)  
Assets    
Current assets    
63%; width:63%; min-width:63%;">Cash and cash equivalents2%; width:2%; min-width:2%;"> 1%; width:1%; min-width:1%;">$15%; width:15%; min-width:15%;">   212,688 1%; width:1%; min-width:1%;"> 1%; width:1%; min-width:1%;"> 1%; width:1%; min-width:1%;">$15%; width:15%; min-width:15%;">  96,5761%; width:1%; min-width:1%;"> 
Short-term marketable securities (amortized cost of $340,952 and $479,791, respectively)     342,485      480,290 
Accounts receivable, net    9,382     12,676 
Inventory  10,518     9,069 
Prepaid expenses and other current assets    9,573     14,079 
Total current assets    584,646     612,690 
Long-term assets    
Property and equipment, net  24,952     60,355 
Operating lease right-of-use assets  31,058    
Long-term marketable securities (amortized cost of $98,847 and $105,263, respectively)    100,618    105,435  
Restricted cash    2,138     2,138 
Intangible assets, net    11,504     11,928 
Goodwill    118,972     118,972 
Other assets    998     784 
Total assets $  874,886  $  912,302 
Liabilities and shareholders’ equity     
Current liabilities    
Accounts payable $  3,895  $  4,453 
Accrued liabilities    3,804     4,371 
Accrued compensation and benefits    4,177     8,124 
Current portion of deferred rent    —     371 
Current operating lease liabilities  1,502    
Current deferred revenue    64,572     60,994 
Total current liabilities    77,950     78,313 
Long-term liabilities    
Deferred rent liability, less current portion     —     6,918 
Operating lease liabilities, less current portion    36,545     — 
Financing obligation    —   36,607  
Deferred revenue, less current portion    208,828   219,332  
Other long-term liabilities  —      93 
Total liabilities    323,323     341,263 
Commitments and contingencies    
Shareholders’ equity    
Preferred stock: $0.0001 par value, 10,000,000 shares authorized at March 31, 2020 and December 31, 2019; no shares issued and outstanding at March 31, 2020 and December 31, 2019       —     — 
Common stock: $0.0001 par value, 340,000,000 shares authorized at March 31, 2020 and December 31, 2019; 126,621,829 and 125,238,142 shares issued and outstanding at March 31, 2020 and December 31, 2019, respectively    12     12 
Additional paid-in capital    945,026     935,834 
Accumulated other comprehensive gain    3,313     671 
Accumulated deficit    (396,788)    (365,478)
Total shareholders’ equity    551,563     571,039 
Total liabilities and shareholders’ equity $  874,886  $  912,302 
     

Adjusted EBITDA

The following table sets forth a reconciliation between our Adjusted EBITDA and our net loss, the most directly comparable GAAP financial measure, for each of the periods presented (in thousands):

100%; border-collapse:collapse !important;">
   

Three Months Ended  March 31, 
64%; width:64%; min-width:64%;"> 1%; width:1%; min-width:1%;"> 1%; width:1%; min-width:1%;"> 15%; width:15%; min-width:15%;">20201%; width:1%; min-width:1%;"> 1%; width:1%; min-width:1%;"> 1%; width:1%; min-width:1%;"> 15%; width:15%; min-width:15%;">20191%; width:1%; min-width:1%;"> 
         
  (unaudited)
Net loss $  (31,403) $  (18,386)
Interest and other income, net    (2,894)    (1,659)
Income tax benefit    (323)    — 
Depreciation and amortization expense    1,978     1,783 
Share-based compensation expense    4,675     3,046 
Adjusted EBITDA $ (27,967) $  (15,216)

FAQ

What were Adaptive Biotechnologies' Q1 2020 earnings results?

In Q1 2020, Adaptive Biotechnologies reported revenues of $20.9 million, a 65% increase from the previous year.

How did COVID-19 impact Adaptive Biotechnologies' financial guidance?

The company withdrew its 2020 revenue guidance due to uncertainty surrounding the COVID-19 pandemic.

What partnerships did Adaptive Biotechnologies announce in 2020?

Adaptive Biotechnologies extended its partnership with Microsoft for COVID-19 diagnostics and announced a collaboration with Amgen for therapeutic antibodies.

What was Adaptive Biotechnologies' net loss for Q1 2020?

The net loss for Q1 2020 was $31.4 million, compared to $18.4 million in the same period in 2019.

Adaptive Biotechnologies Corporation

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Biotechnology
Biological Products, (no Disgnostic Substances)
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United States of America
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