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Abivax Announces Former Prometheus COO, Mark Stenhouse, Appointed as Board Observer & Advisor to Abivax

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Abivax has appointed Mark Stenhouse as Board Observer and Advisor. Stenhouse brings over 30 years of biopharma industry experience, most recently serving as COO of Prometheus Biosciences, which was acquired by Merck for $10.8 billion in 2023. Previously, he spent 25+ years at AbbVie, where he led U.S. Immunology as Vice President, overseeing HUMIRA® sales and marketing teams. The appointment aims to support Abivax's progress toward commercialization of obefazimod and strengthen its pipeline, leveraging Stenhouse's extensive experience in gastroenterology and immunology.

Abivax ha nominato Mark Stenhouse come Osservatore del Consiglio e Consulente. Stenhouse porta con sé oltre 30 anni di esperienza nell'industria biopharma, avendo recentemente ricoperto il ruolo di COO di Prometheus Biosciences, acquisita da Merck per 10,8 miliardi di dollari nel 2023. In precedenza, ha trascorso oltre 25 anni in AbbVie, dove ha guidato il settore dell'Immunologia negli Stati Uniti come Vice Presidente, supervisionando le vendite e i team di marketing di HUMIRA®. Questa nomina ha l'obiettivo di supportare i progressi di Abivax verso la commercializzazione di obefazimod e di rafforzare il suo portafoglio, sfruttando l'ampia esperienza di Stenhouse in gastroenterologia e immunologia.

Abivax ha nombrado a Mark Stenhouse como Observador de la Junta y Asesor. Stenhouse aporta más de 30 años de experiencia en la industria biofarmacéutica, habiendo sido recientemente COO de Prometheus Biosciences, que fue adquirida por Merck por 10.8 mil millones de dólares en 2023. Anteriormente, pasó más de 25 años en AbbVie, donde lideró la inmunología en EE. UU. como Vicepresidente, supervisando los equipos de ventas y marketing de HUMIRA®. El nombramiento tiene como objetivo apoyar el progreso de Abivax hacia la comercialización de obefazimod y fortalecer su cartera, aprovechando la amplia experiencia de Stenhouse en gastroenterología e inmunología.

Abivax는 Mark Stenhouse를 이사회 관찰자 및 고문으로 임명했습니다. Stenhouse는 최근 Merck에 108억 달러에 인수된 Prometheus Biosciences의 COO로서 30년 이상의 생명공학 산업 경험을 보유하고 있습니다. 이전에는 AbbVie에서 25년 이상 근무하며, 미국의 면역학 부문 부사장으로 HUMIRA® 판매 및 마케팅 팀을 총괄했습니다. 이번 임명은 Abivax가 obefazimod 상용화에 나아가고, Stenhouse의 광범위한 위장병학 및 면역학 경험을 활용하여 파이프라인을 강화하기 위한 목표입니다.

Abivax a nommé Mark Stenhouse en tant qu'observateur du conseil et conseiller. Stenhouse apporte plus de 30 ans d'expérience dans l'industrie biopharmaceutique, ayant récemment occupé le poste de COO de Prometheus Biosciences, qui a été acquise par Merck pour 10,8 milliards de dollars en 2023. Auparavant, il a passé plus de 25 ans chez AbbVie, où il a dirigé l'immunologie aux États-Unis en tant que vice-président, supervisant les équipes de vente et de marketing de HUMIRA®. Cette nomination vise à soutenir les progrès d'Abivax vers la commercialisation d'obefazimod et à renforcer son portefeuille en tirant parti de l'expérience étendue de Stenhouse en gastro-entérologie et en immunologie.

Abivax hat Mark Stenhouse zum Beobachter des Vorstands und Berater ernannt. Stenhouse bringt über 30 Jahre Erfahrung in der biopharmazeutischen Industrie mit, zuletzt als COO von Prometheus Biosciences, das 2023 für 10,8 Milliarden Dollar von Merck übernommen wurde. Zuvor war er mehr als 25 Jahre bei AbbVie tätig, wo er als Vizepräsident die Immunologie in den USA leitete und die Verkaufs- und Marketingteams von HUMIRA® überwachte. Die Ernennung zielt darauf ab, den Fortschritt von Abivax in Richtung Kommerzialisierung von obefazimod zu unterstützen und die Pipeline zu stärken, indem Stenhouses umfangreiche Erfahrung in Gastroenterologie und Immunologie genutzt wird.

Positive
  • Appointment of experienced executive with 30+ years in biopharma industry
  • Strategic expertise from former COO of Prometheus (acquired for $10.8B)
  • Valuable HUMIRA® commercialization experience from leadership role at AbbVie
  • Addition of expertise in gastroenterology and immunology markets
Negative
  • None.

Abivax Announces Former Prometheus COO, Mark Stenhouse, Appointed as Board Observer & Advisor to Abivax

PARIS, France, November 13, 2024, 10:00 pm CET – Abivax SA (Euronext Paris and Nasdaq: ABVX) (“Abivax” or the “Company”), a clinical-stage biotechnology company focused on developing therapeutics that harness the body’s natural regulatory mechanisms to stabilize the immune response in patients with chronic inflammatory diseases, today announced the appointment of Mark Stenhouse as Board Observer and Advisor to Abivax.

Mr. Stenhouse brings more than 30 years of experience in the biopharma industry. Most recently, he served as Chief Operating Officer of Prometheus Biosciences, a biotechnology company focused on gastrointestinal diseases that was acquired by Merck for $10.8 billion in 2023. Prior to Prometheus, Mr. Stenhouse spent over 25 years at AbbVie, most recently serving as Vice President of U.S. Immunology. In this capacity, Mr. Stenhouse oversaw U.S. sales and marketing teams for HUMIRA®.

In addition to his positions at Prometheus and Abbvie, Mr. Stenhouse held an executive leadership role at Exact Sciences. He holds a Bachelor of Science in Business Administration from the College of Charleston.

Marc de Garidel, Chief Executive Officer of Abivax, said: “We are pleased to welcome Mark to the role of Board Observer and Advisor to Abivax. We expect his perspective and extensive experience in gastroenterology and immunology to undoubtedly support our continued progress as we head toward commercialization of obefazimod and strengthen our pipeline.”  

Mark Stenhouse, Board Observer & Advisor to Abivax, said: “I am impressed with the clinical profile of obefazimod and its potential to address unmet needs in the patient community. I look forward to working alongside the Abivax management team and Board of Directors as the company continues to advance toward key milestones.”

About Obefazimod
Obefazimod, Abivax’s lead investigational drug candidate, is an orally administered small molecule that was demonstrated to potentially enhance the expression of a single microRNA, miR-124. Phase 2 clinical trials in patients with ulcerative colitis (UC) have generated positive data, resulting in the initiation of a pivotal global Phase 3 clinical trial program (ABTECT Program), with first patients enrolled in the United States in October 2022. A Phase 2b clinical trial in Crohn’s disease is ongoing, with the first patient enrolled in October 2024, and exploration of potential combination therapy opportunities in UC is ongoing.

About Abivax
Abivax is a clinical-stage biotechnology company focused on developing therapeutics that harness the body’s natural regulatory mechanisms to stabilize the immune response in patients with chronic inflammatory diseases. Based in France and the United States, Abivax’s lead drug candidate, obefazimod (ABX464), is in Phase 3 clinical trials for the treatment of moderately to severely active ulcerative colitis. More information on the Company is available at www.abivax.com. Follow us on LinkedIn and on X, formerly Twitter, @Abivax.

Contact:
Patrick Malloy
SVP, Investor Relations, Abivax
patrick.malloy@abivax.com
+1 847 987 4878

DISCLAIMER
This press release contains forward-looking statements, including those relating to the Company’s business objectives. Words such as “continue,” “expect,” “forward,” “potential” and variations of such words and similar expressions are intended to identify forward-looking statements. These forward-looking statements include statements concerning or implying the therapeutic potential of Abivax's drug candidates and other statements that are not historical fact. Although Abivax’s management believes that the expectations reflected in such forward-looking statements are reasonable, investors are cautioned that forward-looking information and statements are subject to various risks, contingencies and uncertainties, many of which are difficult to predict and generally beyond the control of Abivax, that could cause actual results and developments to differ materially from those expressed in, or implied or projected by, the forward-looking information and statements. A description of these risks, contingencies and uncertainties can be found in the documents filed by the Company with the French Autorité des Marchés Financiers pursuant to its legal obligations including its universal registration document (Document d’Enregistrement Universel) and in our Annual Report on Form 20-F filed with the U.S. Securities and Exchange Commission on April 5, 2024 under the caption “Risk Factors.” These risks, contingencies and uncertainties include, among other things, the uncertainties inherent in research and development, future clinical data and analysis, decisions by regulatory authorities, such as the FDA or the EMA, regarding whether and when to approve any drug candidate, as well as their decisions regarding labelling and other matters that could affect the availability or commercial potential of such product candidates. Current results are not necessarily indicative of future results. Special consideration should be given to the potential hurdles of clinical and pharmaceutical development including further assessment by the company and regulatory agencies and IRBs/ethics committees following the assessment of preclinical, pharmacokinetic, carcinogenicity, toxicity, CMC and clinical data. Furthermore, these forward-looking statements, forecasts and estimates are only as of the date of this press release. Readers are cautioned not to place undue reliance on these forward-looking statements. Abivax disclaims any obligation to update these forward-looking statements, forecasts or estimates to reflect any subsequent changes that the Company becomes aware of, except as required by law. Information about pharmaceutical products (including products currently in development) that is included in this press release is not intended to constitute an advertisement. This press release is for information purposes only, and the information contained herein does not constitute either an offer to sell, or the solicitation of an offer to purchase or subscribe securities of the Company in any jurisdiction. Similarly, it does not give and should not be treated as giving investment advice. It has no connection with the investment objectives, financial situation or specific needs of any recipient. It should not be regarded by recipients as a substitute for exercise of their own judgment. All opinions expressed herein are subject to change without notice. The distribution of this document may be restricted by law in certain jurisdictions. Persons into whose possession this document comes are required to inform themselves about and to observe any such restrictions.

“Abivax” and the Abivax logo and other trademarks or service marks of Abivax SA in this press release are the property of Abivax SA. All other trademarks, trade names and service marks appearing in this press release are the property of their respective owners. Solely for convenience, the trademarks and trade names in this press release may be referred to without the ® and ™ symbols, but such references should not be construed as any indicator that their respective owners will not assert their rights thereto.


FAQ

Who is Mark Stenhouse and what is his new role at Abivax (ABVX)?

Mark Stenhouse, former COO of Prometheus Biosciences, has been appointed as Board Observer and Advisor to Abivax. He brings over 30 years of biopharma industry experience, including leadership roles at AbbVie and Prometheus.

What experience does Mark Stenhouse bring to Abivax (ABVX)?

Stenhouse brings over 30 years of biopharma experience, including serving as COO of Prometheus Biosciences, VP of U.S. Immunology at AbbVie overseeing HUMIRA® sales, and executive leadership at Exact Sciences.

How will Mark Stenhouse contribute to Abivax's (ABVX) development?

Stenhouse will support Abivax's progress toward commercialization of obefazimod and pipeline strengthening, leveraging his extensive experience in gastroenterology and immunology markets.

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