Company Description
Overview of Angle Plc Surrey
Angle Plc Surrey is a world-renowned company operating in the liquid biopsy space with innovative circulating tumour cell (CTC) solutions. Using cutting-edge microfluidics and advanced assay technologies, the company provides non-invasive diagnostic and research tools that enable comprehensive analysis of cancer biomarkers. With its proprietary Parsortix system and accompanying products such as the Portrait+ CTC Staining Kit and CellKeep slide, Angle Plc Surrey has positioned itself at the forefront of CTC analysis, addressing key clinical and research needs in oncology.
Innovative Technologies and Product Portfolio
The company has developed a robust suite of products designed to capture, isolate, and analyze CTCs from a simple blood sample. Central to this is the FDA cleared and patent protected Parsortix system, which exemplifies the company’s commitment to precision and quality. This system facilitates complete downstream analysis including whole cell imaging, proteomic evaluation, and genomic and transcriptomic assessments. The Portrait+ CTC Staining Kit enhances the visualization and characterization of CTCs by employing advanced immunofluorescence staining techniques, ensuring that even cell populations undergoing epithelial-to-mesenchymal transition are accurately detected.
Another breakthrough innovation is the proprietary CellKeep slide technology. Developed over several years, this technology addresses the significant challenge of CTC loss during microscopy-based assessments. By reducing cell loss and preserving morphological integrity, the CellKeep slide not only increases assay sensitivity but also optimizes cost efficiency by consolidating CTCs into a defined area for analysis.
Clinical Applications and Research Integration
Angle Plc Surrey’s technologies have profound applications in clinical oncology and translational research. Their liquid biopsy solutions enable a minimally invasive window into the dynamic landscape of tumor biology. By capturing CTCs from patient blood samples, the company’s products help inform diagnostic decisions, monitor treatment efficacy, and guide targeted therapeutic strategies. This approach is particularly beneficial where traditional invasive tissue biopsies are impractical or insufficient for ongoing disease monitoring.
Numerous peer-reviewed studies have validated the efficacy of the Parsortix system, reinforcing its suitability for a broad spectrum of cancer types. Its application in clinical trials and pharmaceutical studies has further established the company as a trusted partner in drug development. Additionally, collaborations that incorporate next generation sequencing assays using proprietary pan-cancer panels illustrate the company’s innovative drive in delivering comprehensive cancer profiling.
Strategic Collaborations and Market Position
Angle Plc Surrey maintains a solid competitive position through a combination of technological innovation, rigorous research validation, and strategic partnerships. The company has engaged with leading clinical stage biotechnology firms, facilitating pilot studies and extended collaborations that seek to integrate molecular profiling with liquid biopsy techniques. These collaborations not only broaden the application of its technologies but also enhance its market penetration across clinical diagnostics and pharmaceutical services sectors.
By focusing on technologies that improve assay sensitivity and reduce procedural cell loss, Angle Plc Surrey distinguishes itself from competitors that rely on traditional, epitope-dependent systems. Its offerings provide a more comprehensive analysis by capturing diverse CTC phenotypes and clusters, which are critical in understanding metastasis and drug resistance. The company’s integrated approach, combining its core Parsortix system with enhancements like the Portrait+ kit and CellKeep slide, underscores its commitment to advancing personalized medicine and precision oncology.
Quality, Compliance, and Intellectual Property
Quality and compliance are deeply embedded in Angle Plc Surrey’s operational ethos. The company’s diagnostic products and clinical services adhere to rigorous regulatory standards, ensuring reliable performance and reproducibility. The secured intellectual property rights—including European and pending US patents—play a crucial role in protecting its technological advancements and sustaining competitive advantages in the market.
Extensive Industry Validation
Over 90 peer-reviewed publications have affirmed the performance and utility of the Parsortix system, demonstrating its reliability and effectiveness in various oncological applications. This extensive body of research not only guides clinical practices but also informs future technological innovations, solidifying the company’s standing as an expert in the field of liquid biopsy and CTC analysis.
Conclusion
In summary, Angle Plc Surrey combines state-of-the-art liquid biopsy technology with a deep commitment to research and clinical excellence. Its comprehensive suite of products—from the Parsortix system to the transformative CellKeep technology—enables precise and robust analysis of circulating tumour cells across diverse cancer types. By bridging the gap between innovative diagnostics and practical clinical applications, the company continues to exert a significant influence in the domains of oncology research, drug development, and clinical diagnostics, providing critical tools that enhance our understanding of cancer dynamics.
This detailed overview is designed to provide investors, researchers, and clinical practitioners with an in-depth look at Angle Plc Surrey’s business model, its technological advancements, and its strategic market positioning. The company remains a pivotal player in the realm of precision oncology, reinforcing its commitment to driving substantive improvements in cancer diagnosis and treatment through liquid biopsy innovations.
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