Exicure, Inc. - XCUR STOCK NEWS

Exicure, Inc. (NASDAQ:XCUR) reported impressive financial results for 2020, achieving $16.6 million in revenue, up from $1.3 million in 2019, primarily due to a collaboration with AbbVie. The net loss reduced to $24.7 million from $26.3 million year-over-year. Key advancements included the initiation of IND-enabling studies for XCUR-FXN targeting Friedreich’s ataxia and multiple FDA designations for cavrotolimod (AST-008), enhancing its oncology pipeline. Despite COVID-19 related delays, Exicure expects sufficient cash runway for the next 12 months to support ongoing trials.

Exicure, Inc. (NASDAQ: XCUR) has announced the addition of Elizabeth Garofalo, M.D. and Andrew Sassine to its Board of Directors during a pivotal time for the company. The appointments are expected to enhance Exicure's development of its investigational drugs, cavrotolimod and XCUR-FXN. Garofalo brings over 25 years of clinical development experience, while Sassine contributes extensive financial expertise. Additionally, David Walt, Ph.D. will not seek re-election at the upcoming Annual Meeting. Exicure focuses on innovative therapies utilizing its proprietary Spherical Nucleic Acid technology.

Exicure, Inc. (NASDAQ: XCUR) announced that the FDA has granted Orphan Drug Designation for its candidate cavrotolimod (AST-008) targeting Merkel cell carcinoma (MCC). This designation is a significant step towards addressing unmet medical needs for MCC patients. Exicure previously received Fast Track designations for cavrotolimod for MCC and cutaneous squamous cell carcinoma (CSCC). Cavrotolimod is currently in Phase 1b/2 clinical trials, showing promising anti-tumor activity with no serious adverse events reported thus far.

Exicure, Inc. (Nasdaq: XCUR) announced that CEO David Giljohann will present at the 2021 H.C. Wainwright Global Life Sciences Conference on March 9-10, 2021. The presentation will be available for registered attendees to view on-demand starting March 9, 2021, at 7:00 AM EST, and it will be archived for 90 days. Exicure is a biotechnology firm focusing on gene regulatory therapies using its proprietary Spherical Nucleic Acid (SNA) technology, currently in preclinical development for Friedreich’s ataxia and advancing in clinical trials for solid tumors.

Exicure, Inc. (Nasdaq: XCUR) has announced its participation in 1x1 meetings with institutional investors at the 10th Annual SV Leerink Global Healthcare Conference from February 24 to 26, 2021. The company focuses on gene regulatory and immunotherapeutic drug development using its proprietary Spherical Nucleic Acid (SNA™) technology. Exicure is currently advancing its drug candidate XCUR-FXN for Friedreich’s ataxia and conducting a Phase 1b/2 trial for AST-008 in advanced solid tumors. The company is headquartered in Chicago, IL, with an office in Cambridge, MA.

Exicure, Inc. (Nasdaq: XCUR) announced that CEO David Giljohann will present at the BIO CEO & Investor Digital Conference from February 16-18, 2021. The presentation will be available for on-demand viewing for registered attendees beginning February 15, 2021. Attendees can schedule 1x1 meetings with Exicure during the conference. With a focus on gene regulatory and immunotherapeutic drugs, Exicure is developing therapeutics targeting neurological and inflammatory diseases utilizing its proprietary Spherical Nucleic Acid (SNA) technology.

Exicure, Inc. (NASDAQ: XCUR) has received Fast Track designations from the FDA for cavrotolimod (AST-008) targeting advanced Merkel cell carcinoma and cutaneous squamous cell carcinoma, both refractory to prior therapies. Cavrotolimod enhances immune responses and is currently in a Phase 1b/2 trial, showing a 21% overall response rate in evaluable patients, including durable responses exceeding six months. No serious adverse events were reported, and significant immune cell activation was observed. This designation highlights the urgent need for novel therapies in these cancer types.

Exicure, Inc. (NASDAQ: XCUR) has appointed James Sulat to its Board of Directors, bringing extensive biopharmaceutical experience. Sulat has held leadership roles at various firms and currently serves on the boards of Valneva SE and Arch Therapeutics. His background in business development and finance is expected to support Exicure's growth. Additionally, Jay Venkatesan has resigned from the Board, effective December 29, 2020. The company focuses on gene regulatory therapies targeting cancer and genetic disorders using its proprietary SNA™ technology, with its lead program in a Phase 1b/2 trial.

Exicure, Inc. (NASDAQ: XCUR) will host a virtual R&D Day on January 7, 2021, to discuss its neuroscience pipeline, focusing on its lead program for Friedreich’s Ataxia (FA). The company reported that XCUR-FXN has moved into IND-enabling studies, with updates on other preclinical programs targeting SCN9A for neuropathic pain and CLN3 for Batten Disease. Exicure will showcase CNS biodistribution studies of its SNA™ therapeutics. Despite the absence of therapies for FA, the meeting aims to engage stakeholders in discussions about future clinical developments.