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Voyager Therapeutics, Inc., listed on Nasdaq under the symbol VYGR, is a pioneering gene therapy company dedicated to developing transformative treatments for severe neurological diseases. Founded in 2014 by leaders in the fields of AAV gene therapy and neuroscience, Voyager focuses on conditions like Parkinson's disease, a monogenic form of amyotrophic lateral sclerosis (ALS), and Friedreich's ataxia. Headquartered in Cambridge, Massachusetts, the company leverages its proprietary TRACER™ AAV capsid discovery platform to create gene therapies with high efficacy and broad brain penetration.
The company’s gene therapy platform, TRACER™ (Tropism Redirection of AAV by Cell-type-specific Expression of RNA), allows for the engineering, optimization, and delivery of AAV-based therapies. This platform has enabled the discovery of novel capsids that exhibit enhanced penetration of the blood-brain barrier and targeted delivery to central nervous system (CNS) tissues.
Voyager's pipeline includes several promising programs. The most advanced is the anti-tau antibody VY-TAU01, aimed at treating Alzheimer’s disease and expected to generate key tau PET imaging data by 2026. Other pipeline projects include gene therapies targeting SOD1 for ALS, and FXN gene therapy for Friedreich’s ataxia.
Financially, Voyager maintains a robust balance sheet. As of December 31, 2023, Voyager reported approximately $431 million in pro-forma cash. This financial strength supports the company’s ongoing clinical trials and the advancement of its gene therapy programs. Voyager collaborates with several industry leaders, including Alexion, AstraZeneca Rare Disease, Novartis Pharma AG, Neurocrine Biosciences, Inc., and Sangamo Therapeutics, Inc. These partnerships provide additional resources and expertise to accelerate the development and commercialization of its therapeutic candidates.
Voyager's achievements have garnered attention within the biotechnology industry. The company's commitment to innovation and the development of life-changing treatments makes it a significant player in the field of gene therapy.
For the latest updates, financial results, and news about Voyager Therapeutics, visit their website at www.voyagertherapeutics.com.
Voyager Therapeutics (Nasdaq: VYGR), a biotechnology company focused on neurogenetic medicines, has announced its upcoming second quarter 2024 financial results release and conference call. The company will report its Q2 2024 financial and operating results after market close on Tuesday, August 6, 2024. Following this, Voyager will host a conference call and webcast at 4:30 p.m. ET.
Interested participants can register for the telephone conference in advance through a provided link. A live webcast will be available on the Investors section of Voyager's website, with a replay accessible for at least 30 days after the call.
Voyager Therapeutics (Nasdaq: VYGR), a biotechnology company focusing on neurogenetic medicines, has granted inducement awards to new employee Eric Hall, Ph.D., M.B.A. The awards, approved by the Compensation Committee under Nasdaq Listing Rule 5635(c)(4), include:
1. A non-qualified stock option for 36,000 shares, effective July 22, 2024, with a ten-year term and an exercise price of $8.77 per share. It vests over four years: 25% after one year, then 75% monthly over three years.
2. Restricted stock units for 18,000 shares, effective October 1, 2024, vesting annually in equal installments over three years.
Both awards are subject to Dr. Hall's continued employment with Voyager and the terms of their respective award agreements.
Voyager Therapeutics (Nasdaq: VYGR) announced the induction of Nathan Jorgensen, Ph.D., M.B.A., into their team with a notable employment agreement. This agreement includes a non-qualified stock option for 200,000 shares and restricted stock units (RSUs) for 80,000 shares as part of the inducement process, approved by the Compensation Committee under Nasdaq Listing Rule 5635(c)(4). The stock option, effective July 8, 2024, carries an exercise price of $7.79 per share, matching the closing price on the effective date. The options vest over four years, with 25% vesting on the first anniversary and the remaining 75% in equal monthly installments over the next three years. The RSUs will vest annually in equal installments over three years starting October 1, 2024. These equity awards are contingent upon Dr. Jorgensen's ongoing employment with Voyager and are subject to specific award agreements.
Voyager Therapeutics (Nasdaq: VYGR), a biotech company specializing in neurogenetic medicines, will participate in two virtual investor conferences in June 2024.
The company will present at the TD Cowen Genetic Medicines & RNA Summit on June 20 at 1:35 p.m. ET and at the H.C. Wainwright 5th Annual Neuro Perspectives Virtual Conference on June 27 at 7:00 a.m. ET. Both presentations will be webcasted and available on Voyager’s investor website, with replays accessible for at least 30 days.
Voyager Therapeutics (Nasdaq: VYGR) announced the appointment of Nathan Jorgensen, Ph.D., MBA, as Chief Financial Officer, effective July 8, 2024. Jorgensen, bringing extensive experience in investment banking, healthcare investing, and biotech operations, previously served as CFO at Vor Biopharma. He raised over $400 million in financings and managed various operational domains. Voyager's CEO, Alfred W. Sandrock, Jr., emphasized Jorgensen's blend of strategic leadership and neuroscience expertise as important for advancing their neurotherapeutics pipeline. Jorgensen expressed enthusiasm for Voyager's innovative platform and its potential to overcome neurology delivery challenges.
Voyager Therapeutics announced the dosing of the first participants in a Phase 1a single ascending dose (SAD) trial of VY-TAU01, an investigational anti-tau antibody designed to inhibit the spread of pathological tau in Alzheimer's disease. This randomized, double-blind, placebo-controlled trial aims to assess the safety and pharmacokinetics of VY-TAU01 in healthy adults. Conducted at a single U.S. site, the trial plans to enroll around 48 patients. Data from this trial will inform a Phase 1b multiple ascending dose (MAD) trial in early Alzheimer's patients, expected to begin in 2025, with initial imaging data potentially available by late 2026. Chief Medical Officer Toby Ferguson highlighted this milestone as a testament to Voyager's neurology drug development capabilities.
Voyager Therapeutics reported its first quarter 2024 financial and operating results, highlighting several milestones and future expectations. The company received IND clearance for its anti-tau antibody VY-TAU01 for Alzheimer's disease and plans to start a trial soon. Development candidates were chosen for the GBA1 and Friedreich’s Ataxia gene therapy programs, with potential clinical entries in 2025. Voyager appointed Dr. Toby Ferguson as Chief Medical Officer. The company completed a $100 million public offering and announced a strategic collaboration with Novartis, which included an $80 million upfront payment and $20 million in newly issued equity. Voyager’s cash position is strong at approximately $400 million, providing financial runway into 2027. However, collaboration revenue dropped from $150.5 million in Q1 2023 to $19.5 million in Q1 2024, leading to a net loss of $11.3 million compared to a net income of $124 million in the same period last year. R&D expenses increased due to program-related spending.
Voyager Therapeutics, Inc. presented data on second-generation TRACER™-Generated Capsids and CNS Gene Therapy Programs at the ASGCT 27th Annual Meeting. The data showed enhanced blood-brain barrier penetrance, broad CNS biodistribution, and robust transduction of key cell types, supporting the high translational potential of TRACER capsids for gene therapy in the CNS. The company aims to file INDs for three development candidates in neurologic diseases by 2025.
Voyager Therapeutics, Inc. (Nasdaq: VYGR) will report its first quarter 2024 financial and operating results on May 13, 2024. The company will host a conference call and webcast to review the results. Participants can join via telephone or live webcast. Registration is required.
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