Welcome to our dedicated page for Vincerx Pharma news (Ticker: VINC), a resource for investors and traders seeking the latest updates and insights on Vincerx Pharma stock.
Vincerx Pharma, Inc. (Nasdaq: VINC) is a pioneering clinical-stage biopharmaceutical company focused on developing novel therapies to address the unmet medical needs of patients with cancer. Operating primarily in the United States, Vincerx leverages its extensive expertise in oncology to advance a diverse pipeline of cutting-edge treatments.
The company is dedicated to the development, manufacturing, and commercialization of small molecule drug programs and a preclinical-stage bioconjugation/next-generation antibody-drug conjugate (ADC) platform, known as VersAptx™. This platform allows for the creation of bespoke bioconjugates that combine different targeting, linker, and payload technologies to address various cancer biologies.
- VIP943: A next-generation ADC targeting CD123, designed to treat leukemias and myelodysplastic syndrome. Currently in Phase 1 clinical trials, VIP943 has shown promising safety profiles and rapid enrollment in its dose-escalation studies.
- VIP236: A first-in-class small molecule drug conjugate (SMDC) aimed at advanced solid tumors, VIP236 is also in Phase 1 trials and demonstrates promising early clinical activity.
- VIP924: Another ADC from the VersAptx platform, targeting CXCR5 for the treatment of B-cell malignancies. Preclinical data show superior efficacy and safety compared to existing treatments.
- Enitociclib: A selective CDK9 inhibitor under investigation for hematologic malignancies and solid tumors, currently in a Phase 1 trial in collaboration with the National Institutes of Health (NIH).
Recent corporate highlights include:
- Announcing positive preliminary Phase 1 data for VIP236 at the American Association for Cancer Research (AACR) Annual Meeting 2024.
- Presenting preclinical data at the 65th Annual Meeting of the American Society for Hematology (ASH 2023) demonstrating the potential of VIP943 and VIP924 in treating various cancers.
- Collaborations with key scientific advisory board members and institutions like the NIH to further clinical research and trials.
Financial results for the first quarter of 2024 show sustained momentum across their pipeline, with recent financing providing the capital needed to support ongoing dose-escalation studies for VIP943 and VIP236.
Vincerx's strong management team, with a proven track record in oncology drug development, continues to drive the company's mission of bringing paradigm-shifting therapeutics to market. Based in Palo Alto, California, with a research facility in Monheim, Germany, Vincerx is well-positioned to capitalize on the growing industry enthusiasm for bioconjugates and ADCs.
For more information, please visit www.vincerx.com.
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Vincerx Pharma, Inc. to host a virtual investor event to review preliminary clinical data from its Phase 1 dose-escalation study of VIP236 and provide an update on pipeline progress. The event will feature presentations by key opinion leaders and the CEO, Ahmed Hamdy, MD. The company aims to address unmet medical needs in cancer treatment through innovative therapeutics.
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Vincerx Pharma, Inc. reported financial results for Q4 and full year 2023, showcasing progress in their clinical programs including VIP236, VIP943, and enitociclib. VIP236, a first-in-class SMDC, and VIP943, a novel CD123-targeted ADC, are in Phase 1 trials, with encouraging preliminary data. Enitociclib, a CDK9 inhibitor, demonstrated promising results in Phase 1 combination studies. Vincerx's VersAptx platform showed significant advancements in bioconjugation technologies. The company's cash runway is expected to last into early Q3 2024.
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Vincerx Pharma, Inc. announced the presentation of three posters at the AACR Annual Meeting 2024, including clinical data for VIP236, a small molecule-drug conjugate. The company will host a virtual investor event on April 8 to discuss preliminary Phase 1 data for VIP236. Vincerx aims to address unmet medical needs in cancer treatment through innovative therapeutics.
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Vincerx Pharma, a biopharmaceutical company (Nasdaq: VINC), announced promising clinical results from a Phase 1 NIH-sponsored study of enitociclib in combination with venetoclax and prednisone for the treatment of relapsed/refractory lymphoma. The study reported 2 partial responses in 3 peripheral T-cell lymphoma patients and 1 partial response in 2 double-hit diffuse large B-cell lymphoma patients. Vincerx is also on track to report early clinical data from lead VersAptx™ platform compounds, VIP236 (early 2024) and VIP943 (mid 2024). Enitociclib is being hailed as a well-tolerated and effective partner for novel combinations, showing a high response rate and tolerability in patients with hard-to-treat types of non-Hodgkin’s lymphoma such as PTCL and DH-DLBCL.
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Vincerx Pharma, Inc. (Nasdaq: VINC) presented preclinical data for VIP943 and VIP924 at ASH 2023. VIP943, a CD123-targeted antibody-drug conjugate, showed on-target selectivity and activity in AML cell lines. VIP924, a CXCR5-targeted ADC, demonstrated superior efficacy and safety compared to commercially available B-cell targeted ADCs.
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Vincerx Pharma, Inc. (Nasdaq: VINC) reported progress across all three clinical programs, including VIP943, the first antibody-drug conjugate (ADC) from the VersAptx Platform, and VIP236, a small molecule-drug conjugate (SMDC) for solid tumors. The company also provided a corporate update, highlighting the positive clinical results, FDA approval, and financial position.
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Vincerx Pharma, Inc. will present three posters at the 65th American Society for Hematology Meeting. The posters will cover VIP943, a CD123-targeting antibody-drug conjugate (ADC) for the treatment of acute myeloid leukemia (AML), myelodysplastic syndrome (MDS), and B-cell acute lymphoblastic leukemia (B-cell ALL). VIP924, a CXCR5 ADC for the treatment of B-cell malignancies, will also be discussed. Additionally, preclinical data on enitociclib's activity in pediatric leukemia will be presented.
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Vincerx Pharma to participate in Cantor Fitzgerald Global Healthcare Conference 2023
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Vincerx Pharma reports dosing of first patient in Phase 1 trial for VIP943
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Vincerx Pharma receives FDA clearance for Phase 1 trial of VIP943, their first candidate from next-generation ADC platform. Positive year with 2 IND clearances in 8 months. Preliminary results for VIP236 expected by late 2023 or early 2024.
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FAQ
What is the current stock price of Vincerx Pharma (VINC)?
The current stock price of Vincerx Pharma (VINC) is $1.65 as of January 28, 2025.
What is the market cap of Vincerx Pharma (VINC)?
The market cap of Vincerx Pharma (VINC) is approximately 3.8M.
What is the focus of Vincerx Pharma, Inc.?
Vincerx Pharma, Inc. is focused on developing novel therapies to address unmet medical needs in cancer treatment, leveraging their expertise in oncology and bioconjugation technology.
What is the VersAptx platform?
VersAptx is a next-generation bioconjugation platform that allows for the creation of bespoke bioconjugates by combining different targeting, linker, and payload technologies to address various cancer biologies.
What are Vincerx's key products in development?
Key products include VIP943 (an ADC for leukemias and myelodysplastic syndrome), VIP236 (a SMDC for advanced solid tumors), VIP924 (an ADC for B-cell malignancies), and Enitociclib (a CDK9 inhibitor for hematologic malignancies and solid tumors).
Where is Vincerx Pharma, Inc. based?
Vincerx Pharma, Inc. is based in Palo Alto, California, with a research facility in Monheim, Germany.
What recent progress has Vincerx made in their clinical programs?
Vincerx has reported positive preliminary Phase 1 data for VIP236, presented new preclinical data for VIP943 and VIP924, and continues dose-escalation studies for both VIP236 and VIP943.
Who conducts Vincerx Pharma's clinical trials?
Vincerx Pharma conducts its clinical trials in collaboration with institutions like the National Institutes of Health (NIH) and key scientific advisory board members.
How does Vincerx ensure the safety and efficacy of their ADCs?
Vincerx's ADCs are designed with proprietary effector chemistry to reduce non-specific release of the payload, ensuring accumulation in cancer cells versus healthy cells, thus improving the therapeutic index.
What financial support has Vincerx recently secured?
Recent financing has provided capital to support ongoing dose-escalation studies for their ADC, VIP943, and SMDC, VIP236.
What is the significance of VIP943 in cancer treatment?
VIP943 is a next-generation ADC targeting CD123, designed to treat leukemias and myelodysplastic syndrome, with promising safety profiles and rapid enrollment in its Phase 1 dose-escalation studies.
What are the future plans for Vincerx Pharma, Inc.?
Vincerx plans to continue advancing their clinical programs, maximizing the value of their VersAptx platform, and presenting more advanced dose-escalation data for VIP236 and VIP943 by the end of 2024.
Vincerx Pharma, Inc.
Nasdaq:VINC
VINC Rankings
VINC Stock Data
3.76M
31.10M
15.68%
24.4%
1.25%
Biotechnology
Pharmaceutical Preparations
United States of America
PALO ALTO