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Vincerx Pharma, Inc. (Nasdaq: VINC) is a pioneering clinical-stage biopharmaceutical company focused on developing novel therapies to address the unmet medical needs of patients with cancer. Operating primarily in the United States, Vincerx leverages its extensive expertise in oncology to advance a diverse pipeline of cutting-edge treatments.
The company is dedicated to the development, manufacturing, and commercialization of small molecule drug programs and a preclinical-stage bioconjugation/next-generation antibody-drug conjugate (ADC) platform, known as VersAptx™. This platform allows for the creation of bespoke bioconjugates that combine different targeting, linker, and payload technologies to address various cancer biologies.
- VIP943: A next-generation ADC targeting CD123, designed to treat leukemias and myelodysplastic syndrome. Currently in Phase 1 clinical trials, VIP943 has shown promising safety profiles and rapid enrollment in its dose-escalation studies.
- VIP236: A first-in-class small molecule drug conjugate (SMDC) aimed at advanced solid tumors, VIP236 is also in Phase 1 trials and demonstrates promising early clinical activity.
- VIP924: Another ADC from the VersAptx platform, targeting CXCR5 for the treatment of B-cell malignancies. Preclinical data show superior efficacy and safety compared to existing treatments.
- Enitociclib: A selective CDK9 inhibitor under investigation for hematologic malignancies and solid tumors, currently in a Phase 1 trial in collaboration with the National Institutes of Health (NIH).
Recent corporate highlights include:
- Announcing positive preliminary Phase 1 data for VIP236 at the American Association for Cancer Research (AACR) Annual Meeting 2024.
- Presenting preclinical data at the 65th Annual Meeting of the American Society for Hematology (ASH 2023) demonstrating the potential of VIP943 and VIP924 in treating various cancers.
- Collaborations with key scientific advisory board members and institutions like the NIH to further clinical research and trials.
Financial results for the first quarter of 2024 show sustained momentum across their pipeline, with recent financing providing the capital needed to support ongoing dose-escalation studies for VIP943 and VIP236.
Vincerx's strong management team, with a proven track record in oncology drug development, continues to drive the company's mission of bringing paradigm-shifting therapeutics to market. Based in Palo Alto, California, with a research facility in Monheim, Germany, Vincerx is well-positioned to capitalize on the growing industry enthusiasm for bioconjugates and ADCs.
For more information, please visit www.vincerx.com.
PALO ALTO, Calif., April 07, 2021 (GLOBE NEWSWIRE) -- Vincerx Pharma (Nasdaq: VINC) will host a key opinion leader (KOL) meeting on bioconjugation and CDK9 inhibitors on April 16, 2021, at 12:00 PM ET. KOLs Brian Druker, M.D., and Anthony W. Tolcher, M.D., will present and answer questions regarding advancements in cancer treatments. Vincerx will also discuss its novel small molecule drug conjugate targeting multiple cancers and its bioconjugation platform, which includes several promising candidates for hematologic tumors.
Vincerx Pharma announced the redemption of all outstanding public warrants to purchase its common stock, effective May 5, 2021. The redemption price is set at $0.01 per warrant. These warrants can be exercised until the redemption date, where unexercised warrants will become void. The company has met the criteria for redemption, as its stock price has consistently exceeded $16.50 for 20 trading days within the past 30 days. A total of 6,563,767 public warrants were issued, potentially raising approximately $37.7 million if fully exercised.
Vincerx Pharma, a biopharmaceutical firm focused on cancer therapeutics, has established a Scientific Advisory Board (SAB) led by John C. Byrd, M.D. The board includes renowned experts in oncology, enhancing Vincerx's capacity to advance its oncology pipeline. CEO Ahmed Hamdy emphasized that the SAB's expertise is pivotal for the development of VIP152, a CDK9 inhibitor targeting hematologic malignancies and solid tumors. The company's strategic direction is strengthened with the formation of this board, aimed at addressing unmet medical needs in cancer treatment.
Vincerx Pharma, Inc. (Nasdaq: VINC) made significant strides with an exclusive license agreement with Bayer AG for its oncology portfolio, including the promising CDK9 inhibitor VIP152. The company raised about $62 million through a successful business combination on December 23, 2020. Leadership was strengthened with new appointments, enhancing strategic direction. Phase 1b studies for VIP152 will begin in 2021, targeting Myc-driven hematologic malignancies. Financially, Vincerx ended Q4 2020 with $61.8 million in cash, though it reported a net loss of $10.7 million for the year.
PALO ALTO, Calif., March 10, 2021 - Vincerx Pharma (Nasdaq: VINC) announced a poster presentation at the AACR Annual Meeting 2021, scheduled for April 10-15, 2021. The poster titled 'A novel small molecule drug conjugate' focuses on a new drug designed to treat multiple cancer types. The presentation will be led by Hans-Georg Lerchen as part of the Experimental and Molecular Therapeutics session. Vincerx, a clinical-stage life sciences company, aims to address unmet medical needs in oncology through innovative therapies.
Vincerx Pharma announces the appointment of three key executives: Hermes Garbán as Chief Medical Officer, Hans-Georg Lerchen as Chief Scientific Officer, and Tom Thomas as General Counsel and Chief Legal Officer. This strategic move aims to enhance the management team as the company advances its pipeline of targeted oncology therapeutics. Key milestones for 2021 include the initiation of Phase 1b studies for VIP52, a potent CDK9 inhibitor, in treating various cancers, including hematologic malignancies.
PALO ALTO, Calif., Feb. 24, 2021 – Vincerx Pharma (Nasdaq: VINC) announced a key opinion leader meeting on March 5, 2021, at 12:00pm ET to discuss VIP152, a treatment for hematologic and solid tumors. Esteemed KOLs Ian Flinn, John Byrd, and Howard Burris will present insights on the CDK9 inhibitor landscape. VIP152 has shown early clinical activity in Phase 1 trials, especially in high-need populations like double-hit DLBCL, indicating its potential to disrupt oncogene expression. For webinar registration, click here.
PALO ALTO, Calif., Feb. 17, 2021 – Vincerx Pharma, a biopharmaceutical company focused on innovative cancer therapies, will present a corporate overview at the SVB Leerink 10th Annual Global Healthcare Conference on February 26, 2021, at 10:00 AM ET. CEO Ahmed Hamdy, M.D., and CFO Alex Seelenberger will lead the presentation. The event will be webcast live and archived for 90 days on the company’s website. Vincerx is dedicated to addressing unmet medical needs in cancer treatment through its clinical-stage drug programs and strategic partnerships.
Vincerx, a biopharmaceutical company focused on cancer therapeutics, announced a corporate name change from Vincera Pharma to Vincerx, Inc. on January 7, 2021. The ticker symbols for its common stock, units, and warrants will remain unchanged as 'VINC', 'VINCW', and 'VINCU'. Vincerx aims to address unmet medical needs in cancer treatment through innovative therapies and has a pipeline of products developed under a license agreement with Bayer, including clinical-stage and preclinical programs.
Vincera Pharma, Inc. completed its business combination with LifeSci Acquisition Corp. on December 23, 2020, leading to its listing on the Nasdaq under ticker symbol VINC on December 24, 2020. The transaction yielded net proceeds of approximately $62 million, essential for advancing its oncology therapeutics pipeline, particularly its PTEFb inhibitor and bioconjugation platform. CEO Ahmed Hamdy emphasized the milestone this represents for the company and its plans for clinical advancements.
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