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10x Genomics Reports Fourth Quarter and Full Year 2023 Financial Results and Provides Outlook for 2024

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10x Genomics (TXG) reports Q4 2023 revenue growth of 18% and FY 2023 revenue growth of 20% over 2022. The company launched new products, increased instruments sold, and provided a positive outlook for 2024.
Positive
  • Revenue growth of 18% in Q4 2023 and 20% in FY 2023 compared to 2022.
  • Increased cumulative instruments sold to 5,966 by the end of 2023.
  • Launched preorders for new products and technologies.
  • Gross margin decreased due to product mix with a higher mix of Spatial instruments sold.
  • Operating expenses increased by 20% driven by in-process research and development expenses.
  • Net loss increased in Q4 2023 and FY 2023 compared to the prior year.
  • Provided a positive outlook for 2024 with revenue expected to grow by 8% to 12%.
  • Cash and cash equivalents and marketable securities were $388.7 million as of December 31, 2023.
Negative
  • None.

Insights

The reported revenue growth of 18% for Q4 and 20% for the full year signifies a robust performance by 10x Genomics, especially in the context of the life sciences tools and diagnostics sector. This growth trajectory, coupled with the expanded instrument portfolio, suggests the company is gaining market share and effectively capitalizing on the demand for single cell and spatial biology technologies. However, the decline in gross margin, primarily due to a higher mix of Spatial instruments sold, indicates a shift in the company's sales mix towards potentially lower-margin products, which could impact profitability in the short term.

Additionally, the increase in operating expenses, notably due to in-process research and development and impairment charges, reflects aggressive investment in innovation and potential expansion of capabilities. While this could strain current financials, leading to a larger operating loss, it may position the company for long-term growth if the new products and technologies capture significant market interest. Investors should monitor the balance between growth investments and cost management moving forward.

The launch of new products such as Visium HD Spatial Gene Expression and Chromium GEM-X technology is a strategic move to stay ahead in the competitive landscape of life sciences research. The increased cumulative instruments sold demonstrates market acceptance and the potential for recurring revenue through consumables, which is a key driver for sustainable growth in this sector. However, the company's outlook for 2024 projects a slower revenue growth rate of 8% to 12%, which could signal a maturing market or increased competition.

It is crucial to analyze the adoption rate of the newly launched products and the company's ability to maintain its innovation lead. The operating loss and net loss figures are significant, but not uncommon for companies in growth phases within biotechnology. Stakeholders should weigh the potential future returns of current R&D investments against the risks of prolonged periods of losses.

The single cell and spatial biology fields are rapidly evolving, with significant implications for research and clinical applications. 10x Genomics' focus on these areas, as evidenced by their new product launches and technology advancements, is aligned with the industry's trajectory towards more precise and high-resolution biological analysis. The company's investment in R&D, despite leading to short-term losses, is critical for maintaining a competitive edge in a field where technological obsolescence can occur quickly.

The acquisition of intangible and other assets suggests strategic moves to enhance their technological portfolio, which could lead to new revenue streams or improvements in existing products. However, the market will need to assess whether these investments will translate into commercial success that justifies the current financial impact.

Q4 2023 revenue growth of 18% and FY 2023 revenue growth of 20% over the corresponding periods of 2022

PLEASANTON, Calif., Feb. 15, 2024 /PRNewswire/ -- 10x Genomics, Inc. (Nasdaq: TXG), a leader in single cell and spatial biology, today reported financial results for the fourth quarter and full year ended December 31, 2023 and provided outlook for 2024.

Recent Highlights

  • Revenue was $184.0 million for the fourth quarter and $618.7 million for the full year of 2023, representing 18% and 20% increases over the corresponding periods of 2022.
  • Increased cumulative instruments sold to 5,966 as of the end of 2023, comprising 5,180 Chromium instruments, 531 Visium instruments and 255 Xenium instruments.
  • Launched preorders for Visium HD Spatial Gene Expression, enabling whole transcriptome spatial discovery at single cell-scale resolution.
  • Unveiled and launched preorders for the first two products featuring Chromium GEM-X technology, the next generation of the company's leading single cell technology architecture, enabling higher performance at larger scale and lower cost.

"Our innovation engine has consistently delivered transformational technologies that have enabled our customers to expand the frontiers of science," said Serge Saxonov, Co-founder and CEO of 10x Genomics. "We're building on last year's extraordinary launch of Xenium with new, franchise-defining products in each of our three platforms that will take our portfolio to the next level. Our priority is to ensure our customers' success with these new products as we work together to deliver on the full promise and potential of single cell and spatial biology to advance human health."

Fourth Quarter 2023 Financial Results

Revenue was $184.0 million for the three months ended December 31, 2023, a 18% increase from $156.2 million for the three months ended December 31, 2022. This increase was primarily due to a higher volume of Spatial instruments and consumables sold.

Gross margin was 63% for the fourth quarter of 2023, as compared to 76% for the corresponding prior year period. The decrease in gross margin was primarily due to product mix with a higher mix of Spatial instruments sold.

Operating expenses were $171.0 million for the fourth quarter of 2023, a 20% increase from $142.5 million for the corresponding prior year period. The increase was primarily driven by $19.6 million of in-process research and development expense related to an agreement to acquire certain intangible and other assets earlier this year and impairment charges related to long-lived assets.

Operating loss was $55.2 million for the fourth quarter of 2023, as compared to an operating loss of $23.1 million for the corresponding prior year period. Operating loss also includes $38.9 million of stock-based compensation for the fourth quarter of 2023, as compared to $41.0 million for the fourth quarter of 2022.

Net loss was $49.0 million for the fourth quarter of 2023, as compared to a net loss of $17.2 million for the corresponding prior year period. This includes $19.6 million of in-process research and development expense related to an agreement to acquire certain intangible and other assets earlier this year.

Full Year 2023 Financial Results

Revenue was $618.7 million for the year ended December 31, 2023, a 20% increase from $516.4 million for 2022.

Gross margin was 66% for full year 2023, as compared to 77% for 2022. The decrease in gross margin was primarily due to product mix with a higher mix of Spatial instruments sold.

Operating expenses were $674.6 million for full year 2023, as compared to $564.0 million for 2022, an increase of 20%. The increase was primarily driven by $61.0 million of in-process research and development expense related to an agreement to acquire certain intangible and other assets earlier this year and higher personnel expenses including stock-based compensation expense.

Operating loss was $265.3 million for full year 2023, as compared to an operating loss of $167.9 million for 2022. This includes $167.0 million of stock-based compensation for full year 2023, as compared to $136.8 million for full year 2022.

Net loss was $255.1 million for full year 2023, as compared to a net loss of $166.0 million for 2022. This includes $61.0 million of in-process research and development expense related to an agreement to acquire certain intangible and other assets earlier this year.

Cash and cash equivalents and marketable securities were $388.7 million as of December 31, 2023.

2024 Financial Guidance 

10x Genomics expects full year 2024 revenue to be in the range of $670 million to $690 million, representing 8% to 12% growth over full year 2023 revenue.

Webcast and Conference Call Information

10x Genomics will host a conference call to discuss the fourth quarter and full year 2023 financial results, business developments and outlook after market close on Thursday, February 15, 2024 at 1:30 PM Pacific Time / 4:30 PM Eastern Time. A webcast of the conference call can be accessed at http://investors.10xgenomics.com. The webcast will be archived and available for replay for at least 45 days after the event.

About 10x Genomics

10x Genomics is a life science technology company building products to accelerate the mastery of biology and advance human health. Our integrated solutions include instruments, consumables and software for single cell and spatial biology, which help academic and translational researchers and biopharmaceutical companies understand biological systems at a resolution and scale that matches the complexity of biology. Our products are behind breakthroughs in oncology, immunology, neuroscience and more, fueling powerful discoveries that are transforming the world's understanding of health and disease. To learn more, visit 10xgenomics.com or connect with us on LinkedIn or X (Twitter).

Forward Looking Statements

This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995 as contained in Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended, which are subject to the "safe harbor" created by those sections. All statements included in this press release, other than statements of historical facts, may be forward-looking statements. Forward-looking statements generally can be identified by the use of forward-looking terminology such as "may," "might," "will," "should," "expect," "plan," "anticipate," "could," "intend," "target," "project," "contemplate," "believe," "see," "estimate," "predict," "potential," "would," "likely," "seek" or "continue" or the negatives of these terms or variations of them or similar terminology, but the absence of these words does not mean that a statement is not forward-looking. These forward-looking statements include statements regarding 10x Genomics, Inc.'s product momentum, potential, progress and launches, our expected performance advantages and benefits of using our products and services, customer usage and adoption of our products and our financial performance and results of operations, including our expectations regarding revenue and guidance. These statements are based on management's current expectations, forecasts, beliefs, assumptions and information currently available to management. Actual outcomes and results could differ materially from these statements due to a number of factors and such statements should not be relied upon as representing 10x Genomics, Inc.'s views as of any date subsequent to the date of this press release. 10x Genomics, Inc. disclaims any obligation to update any forward-looking statements provided to reflect any change in our expectations or any change in events, conditions or circumstances on which any such statement is based, except as required by law. The material risks and uncertainties that could affect 10x Genomics, Inc.'s financial and operating results and cause actual results to differ materially from those indicated by the forward-looking statements made in this press release include those discussed under the captions "Risk Factors" and "Management's Discussion and Analysis of Financial Condition and Results of Operations" in the company's most recently-filed 10-K and elsewhere in the documents 10x Genomics, Inc. files with the Securities and Exchange Commission from time to time.

Disclosure Information

10x Genomics uses filings with the Securities and Exchange Commission, our website (www.10xgenomics.com), press releases, public conference calls, public webcasts and our social media accounts as means of disclosing material non-public information and for complying with our disclosure obligations under Regulation FD.

Contacts

Investors: investors@10xgenomics.com

Media: media@10xgenomics.com

10x Genomics, Inc.

Consolidated Statement of Operations

(Unaudited)

(In thousands, except share and per share data)



Three Months Ended
December 31,


Year Ended
December 31,


2023


2022


2023


2022

Revenue (1)

$         183,979


$         156,232


$         618,727


$         516,409

Cost of revenue (2)

68,197


36,827


209,414


120,386

Gross profit

115,782


119,405


409,313


396,023

Operating expenses:








Research and development (2)

65,267


63,614


270,332


265,667

In-process research and development

19,578



60,980


Selling, general and administrative (2)

86,125


78,887


343,330


298,300

Total operating expenses

170,970


142,501


674,642


563,967

Loss from operations

(55,188)


(23,096)


(265,329)


(167,944)

Other income (expense):








Interest income

4,637


2,815


16,906


6,647

Interest expense

(8)


(125)


(33)


(476)

Other income (expense), net

3,961


3,995


(307)


(198)

Total other income

8,590


6,685


16,566


5,973

Loss before provision for income taxes

(46,598)


(16,411)


(248,763)


(161,971)

Provision for income taxes

2,354


804


6,336


4,029

Net loss

$          (48,952)


$          (17,215)


$       (255,099)


$       (166,000)









Net loss per share, basic and diluted

$              (0.41)


$              (0.15)


$              (2.18)


$              (1.46)

Weighted-average shares used to compute net loss per share, basic and diluted

118,565,724


114,757,572


117,165,036


113,858,684









(1)

The following table represents revenue by source for the periods indicated (in thousands). Spatial products includes the Company's Visium and Xenium products:

 



Three Months Ended
December 31,


Twelve Months Ended
December 31,



2023


2022


2023


2022

Instruments









Chromium


$           11,150


$           15,243


$           47,866


$           58,552

Spatial


27,248


7,089


75,605


13,844

Total instruments revenue


38,398


22,332


123,471


72,396

Consumables









Chromium


118,144


120,238


420,316


400,433

Spatial


22,170


11,359


59,237


35,155

Total consumables revenue


140,314


131,597


479,553


435,588

Services


5,267


2,303


15,703


8,425

Total revenue


$         183,979


$         156,232


$         618,727


$         516,409

 

The following table presents revenue by geography based on the location of the customer for the periods indicated (in thousands):



Three Months Ended
December 31,


Twelve Months Ended
December 31,



2023


2022


2023


2022

Americas









United States


$           99,322


$           82,828


$         360,091


$         284,987

Americas (excluding United States)


4,520


2,794


13,101


8,791

Total Americas


103,842


85,622


373,192


293,778

Europe, Middle East and Africa


50,589


43,001


142,276


117,068

Asia-Pacific









China¹


11,748


16,277


50,965


64,356

Asia-Pacific (excluding China)


17,800


11,332


52,294


41,207

Total Asia-Pacific


29,548


27,609


103,259


105,563

Total Revenue


$         183,979


$         156,232


$         618,727


$         516,409



1

Includes Hong Kong effective from the first quarter of 2023. Comparative periods have been adjusted for this inclusion.

 

(2) Includes stock-based compensation expense as follows:


Three Months Ended
December 31,


Year Ended
December 31,

(in thousands)

2023


2022


2023


2022

Cost of revenue

$           1,928


$           1,511


$           7,068


$           5,259

Research and development

17,608


17,865


72,804


59,211

Selling, general and administrative

19,382


21,598


87,078


72,378

Total stock-based compensation expense

$         38,918


$         40,974


$       166,950


$       136,848

 

10x Genomics, Inc.

Consolidated Balance Sheets

(Unaudited)

(In thousands, except share and per share data)



December 31,


2023


2022

Assets




Current assets:




Cash and cash equivalents

$         359,284


$         219,746

Marketable securities

29,411


210,238

Restricted cash


2,633

Accounts receivable, net

114,832


104,211

Inventory

73,706


81,629

Prepaid expenses and other current assets

18,789


16,578

Total current assets

596,022


635,035

Property and equipment, net

279,571


289,328

Restricted cash


4,974

Operating lease right-of-use assets

65,361


69,882

Goodwill

4,511


4,511

Intangible assets, net

16,616


22,858

Other noncurrent assets

3,062


2,392

Total assets

$         965,143


$      1,028,980

Liabilities and stockholders' equity




Current liabilities:




Accounts payable

$           15,738


$           21,599

Accrued compensation and related benefits

30,105


32,675

Accrued expenses and other current liabilities

56,648


59,779

Deferred revenue

13,150


7,867

Operating lease liabilities

11,521


9,037

Total current liabilities

127,162


130,957

Operating lease liabilities, noncurrent

83,849


86,139

Deferred revenue, noncurrent

8,814


3,165

Other noncurrent liabilities

4,275


2,976

Total liabilities

224,100


223,237

Commitments and contingencies




Stockholders' equity:




Preferred stock, $0.00001 par value; 100,000,000 shares authorized, no shares issued or
outstanding as of December 31, 2023 and December 31, 2022


Common stock, $0.00001 par value; 1,100,000,000 shares authorized and 119,095,362
and 115,195,009 shares issued and outstanding as of December 31, 2023 and 2022

2


2

Additional paid-in capital

2,025,890


1,839,397

Accumulated deficit

(1,284,420)


(1,029,321)

Accumulated other comprehensive loss

(429)


(4,335)

Total stockholders' equity

741,043


805,743

Total liabilities and stockholders' equity

$         965,143


$      1,028,980





 

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SOURCE 10x Genomics, Inc

FAQ

What was 10x Genomics' revenue growth in Q4 2023 compared to 2022?

10x Genomics reported a revenue growth of 18% in Q4 2023 over the corresponding period in 2022.

How many instruments did 10x Genomics sell by the end of 2023?

10x Genomics sold 5,966 cumulative instruments by the end of 2023.

What new technology did 10x Genomics launch for spatial gene expression?

10x Genomics launched preorders for Visium HD Spatial Gene Expression, enabling whole transcriptome spatial discovery at single cell-scale resolution.

What is 10x Genomics' financial outlook for 2024?

10x Genomics expects full year 2024 revenue to be in the range of $670 million to $690 million, representing 8% to 12% growth over full year 2023 revenue.

10x Genomics, Inc.

NASDAQ:TXG

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