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Entrada Therapeutics Appoints Dr. Bernhardt Zeiher to its Board of Directors

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Entrada Therapeutics (Nasdaq: TRDA) has appointed Dr. Bernhardt “Bernie” Zeiher to its Board of Directors. Previously, Dr. Zeiher was the Chief Medical Officer at Astellas Pharma, where he played key roles in developing numerous therapeutic products. His extensive experience in clinical and regulatory affairs is expected to benefit Entrada as it progresses its lead drug programs targeting Duchenne muscular dystrophy and myotonic dystrophy type 1. Dr. Zeiher expresses enthusiasm for joining during this growth phase, emphasizing his alignment with Entrada’s mission to innovate in intracellular therapeutics.

Positive
  • Dr. Bernhardt Zeiher brings extensive experience from Astellas Pharma, enhancing Entrada's leadership.
  • His clinical and regulatory insight is expected to support the advancement of key drug programs.
Negative
  • Concerns may arise regarding the continuity of leadership experience as Dr. Zeiher transitions into this role.

BOSTON, April 04, 2023 (GLOBE NEWSWIRE) -- Entrada Therapeutics, Inc. (Nasdaq: TRDA), a biopharmaceutical company aiming to transform the lives of patients by establishing intracellular Endosomal Escape Vehicle (EEV™)-therapeutics as a new class of medicines, today announced the appointment of Dr. Bernhardt “Bernie” Zeiher to its Board of Directors, effective immediately. Dr. Zeiher served most recently as the Chief Medical Officer at Astellas Pharma.

“Bernie is a dynamic life sciences leader and we look forward to having him join our Board of Directors,” said Dipal Doshi, President and Chief Executive Officer of Entrada. “As the former Chief Medical Officer and President of Development at Astellas, Bernie provides invaluable clinical and regulatory insight as we continue to advance our lead programs in Duchenne muscular dystrophy and myotonic dystrophy type 1 as well as broadening our pipeline.”

“Entrada’s EEV platform is transforming the way we think about intracellular therapeutics and I am honored to be joining the Board at this time in its growth,” said Dr. Zeiher. “Entrada’s culture of innovation, collaboration and commitment to patients aligns closely with my own values, and I look forward to working with the team to advance Entrada’s expanding intracellular therapeutics pipeline.”

Dr. Bernhardt Zeiher

Dr. Zeiher started his career at Astellas in 2010 as Vice President and Therapeutic Area Leader for Inflammation, Immunology and Infectious Diseases. He was promoted to Senior Vice President and Therapeutic Area Head for Immunology, Infectious Diseases and Transplant in 2012. Dr. Zeiher was later named Executive Vice President and Therapeutic Area Head when his responsibilities expanded to include the company's development operations and clinical pharmacology departments. He was promoted to President of Development in 2015, and most recently to Chief Medical Officer in 2018. Prior to joining Astellas, Dr. Zeiher served as Vice President of the Inflammation and Immunology Therapeutic Area at Pfizer and Medical Director for Inflammation and Immunology at Eli Lilly. Throughout his career, he has participated in the development and approval of 15 products across multiple therapeutic areas.

Dr. Zeiher earned his Doctor of Medicine at the Case Western Reserve University School of Medicine and completed an internal medicine residency at University Hospitals of Cleveland as well as a fellowship in Pulmonary and Critical Care Medicine at University of Iowa Hospitals and Clinics. He is also a Fellow in the American College of Physicians and the American College of Chest Physicians.

About Entrada Therapeutics
Entrada Therapeutics is a biopharmaceutical company aiming to transform the lives of patients by establishing a new class of medicines, Endosomal Escape Vehicle (EEV™)-therapeutics, to engage intracellular targets that have long been considered inaccessible and undruggable. The Company’s EEV therapeutics are designed to enable the efficient intracellular delivery of a wide range of therapeutics into a variety of organs and tissues, resulting in an improved therapeutic index. Through its proprietary, highly versatile and modular EEV platform, Entrada is building a robust development portfolio of RNA-, antibody- and enzyme-based programs for the potential treatment of neuromuscular, immunological, ocular and metabolic diseases, among others. The Company’s lead oligonucleotide programs include ENTR-601-44 and ENTR-601-45 for the potential treatment of people living with Duchenne who are exon 44 and 45 skipping amenable, respectively, as well as our partnered candidate ENTR-701 targeting myotonic dystrophy type 1 (DM1).

For more information about Entrada, please visit our website, www.entradatx.com, and follow us on Twitter and LinkedIn.

Entrada Investor/Media Contact 
Karla MacDonald 
Chief Corporate Affairs Officer  
kmacdonald@entradatx.com

A photo accompanying this announcement is available at https://www.globenewswire.com/NewsRoom/AttachmentNg/00e760cd-1e56-44dd-a6c7-cb312a87d51d


FAQ

Who is Dr. Bernhardt Zeiher and what is his role at Entrada Therapeutics?

Dr. Bernhardt Zeiher has been appointed to the Board of Directors at Entrada Therapeutics, bringing significant experience as the former Chief Medical Officer at Astellas Pharma.

What impact might Dr. Zeiher's appointment have on Entrada Therapeutics?

His expertise may enhance clinical and regulatory decision-making as Entrada advances its drug development programs.

What are Entrada's lead drug programs that Dr. Zeiher will help advance?

Entrada's lead programs focus on treating Duchenne muscular dystrophy and myotonic dystrophy type 1.

When was Dr. Zeiher appointed to Entrada Therapeutics' Board of Directors?

Dr. Zeiher's appointment was announced on April 4, 2023.

Entrada Therapeutics, Inc.

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