TCR² Therapeutics to Announce Interim Data from Phase 1/2 Clinical Trial of TC-210 in Mesothelin-Expressing Solid Tumors

Rhea-AI Summary

TCR² Therapeutics Inc. (Nasdaq: TCRR) will present interim data from the Phase 1 portion of its TC-210 clinical trial for mesothelin-expressing solid tumors on December 14, 2020. The company will host a conference call and webcast at 8:00 AM ET, which can be accessed via its Investors page. TCR² focuses on innovative T cell therapies, with TC-210 targeting solid tumors and TC-110 aimed at hematological malignancies. These TRuC-T cells demonstrate promising anti-tumor activity in preclinical studies.

Positive

• Upcoming presentation of interim clinical trial data on December 14, 2020.
• TC-210 targeting various solid tumors shows potential in clinical studies.
• Innovative TRuC-T cell therapy demonstrates superior anti-tumor activity compared to CAR-T cells.

Negative

• None.

CAMBRIDGE, Mass., Dec. 11, 2020 (GLOBE NEWSWIRE) -- TCR² Therapeutics Inc. (Nasdaq: TCRR), a clinical-stage immunotherapy company developing a pipeline of novel T cell therapies for patients suffering from cancer, today announced that the Company plans to discuss interim data from the Phase 1 portion of the TC-210 Phase 1/2 clinical trial for patients with mesothelin-expressing solid tumors in a premarket press release and webcast to be held on Monday, December 14^th, 2020.

The Company will host a conference call and webcast with a slide presentation at 8:00am E.T. on Monday, December 14^th. The webcast of the conference call will be made available on the Investors page of the Company’s website at www.investors.tcr2.com. To access the call via dial-in, please dial 866-220-8062 (U.S. toll free) or 470-495-9169 (international) ten minutes prior to the start time with the conference ID number 4070006. Following the live audio webcast, an archived replay will be available for at least 30 days following the presentation.

About TCR² Therapeutics

TCR² Therapeutics Inc. is a clinical-stage immunotherapy company developing a pipeline of novel T cell therapies for patients suffering from cancer. TCR²’s proprietary T cell receptor (TCR) Fusion Construct T cells (TRuC^®-T cells) are a unique therapeutic approach, specifically recognizing and killing cancer cells by harnessing signaling from the entire TCR, independent of human leukocyte antigens (HLA). In preclinical studies, TRuC-T cells have demonstrated superior anti-tumor activity compared to chimeric antigen receptor T cells (CAR-T cells), while exhibiting lower levels of cytokine release. The Company’s lead TRuC-T cell product candidate targeting solid tumors, TC-210, is currently being studied in a Phase 1/2 clinical trial to treat patients with mesothelin-positive non-small cell lung cancer (NSCLC), ovarian cancer, malignant pleural/peritoneal mesothelioma, and cholangiocarcinoma. The Company’s lead TRuC-T cell product candidate targeting hematological malignancies, TC-110, is currently being studied in a Phase 1/2 clinical trial to treat patients with CD19-positive adult acute lymphoblastic leukemia (aALL) and with aggressive or indolent non-Hodgkin lymphoma (NHL). For more information about TCR², please visit www.tcr2.com.

Investor and Media Contact:

Carl Mauch
Director, Investor Relations and Corporate Communications
TCR² Therapeutics Inc.
(617) 949-5667
carl.mauch@tcr2.com

FAQ

What is TCR² Therapeutics planning to announce on December 14, 2020?

TCR² Therapeutics plans to discuss interim data from the Phase 1 portion of the TC-210 clinical trial for mesothelin-expressing solid tumors.

What is the focus of the TC-210 clinical trial?

The TC-210 clinical trial focuses on treating patients with mesothelin-expressing solid tumors, including non-small cell lung cancer, ovarian cancer, and malignant mesothelioma.

How can I access the TCR² Therapeutics conference call?

You can access the conference call on December 14, 2020, by visiting TCR²'s Investors page or dialing in using the provided phone numbers.

What are TRuC-T cells developed by TCR² Therapeutics?

TRuC-T cells are a novel T cell therapy approach that recognizes and kills cancer cells, showing superior anti-tumor activity while minimizing cytokine release.

What does the Phase 1/2 trial involve for TC-210?

The Phase 1/2 trial for TC-210 involves studying its effects on patients with specific solid tumors to evaluate safety and efficacy.