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Protara Therapeutics, Inc. (symbol: TARA) is a clinical-stage biopharmaceutical company specializing in identifying and advancing transformative therapies for individuals afflicted with rare and specialty diseases. Headquartered in New York, New York, the company’s mission is to discover, develop, and deliver breakthrough treatments for patients who have limited therapeutic options.
Protara’s leading program is TARA-002, an investigational cell therapy designed for the treatment of lymphatic malformations (LMs), a condition characterized by fluid-filled cysts. In a significant advancement for the company, TARA-002 has been granted the Rare Pediatric Disease designation by the U.S. Food and Drug Administration (FDA), spotlighting its potential impact on pediatric patients.
Another key asset in Protara’s pipeline is the development of intravenous (IV) choline chloride, a phospholipid substrate replacement therapy aimed at treating Intestinal Failure-Associated Liver Disease (IFALD). This investigational therapy underscores the company's commitment to addressing critical needs in the realm of pediatric and adult rare diseases.
The company's history dates back to its former identity as Artara Therapeutics, Inc. The name change to Protara Therapeutics, Inc. occurred in May 2020, reflecting a refreshed vision and strategic direction.
Protara’s forward-looking strategies are built upon solid research and development foundations, extensive clinical trial engagements, and meaningful partnerships. With recent financial updates, the company has ensured that its cash reserves, bolstered by anticipated net proceeds, can sustain its strategic plans into 2026. This financial planning provides a stable runway for Protara to continue its pioneering work and achieve significant milestones.
The company is actively involved in various clinical trials and regulatory interactions, aiming to bring its innovative therapies to market. Protara’s operational transparency and forward-looking statements indicate a robust business strategy focused on long-term growth and patient success.
For the latest updates on Protara Therapeutics, including performance, events, and developments, visit Protara Therapeutics or contact their offices directly at Justine O'Malley, Justine.OMalley@protaratx.com, 646-817-2836.
Protara Therapeutics, Inc. (Nasdaq: TARA) announced its participation in a virtual fireside chat at the Guggenheim Healthcare Talks 2022 Oncology Conference on February 9, 2022, at 4:00 PM ET. Interested parties can access the live webcast through the Events and Presentations section of the Company’s website, which will remain archived for 90 days post-event. Protara focuses on developing transformative therapies for cancer and rare diseases, including its lead program, TARA-002, aimed at treating non-muscle invasive bladder cancer and lymphatic malformations.
Protara Therapeutics (Nasdaq: TARA) has appointed Dr. Jathin Bandari as Chief Medical Officer. He previously served as the Vice President of Clinical Development and was Interim CMO. Dr. Bandari, a urologic oncologist with extensive experience, will lead the development of TARA-002, a therapy for non-muscle invasive bladder cancer. Under his leadership, Protara aims to advance its oncology portfolio and explore new applications for TARA-002. Dr. Bandari is a respected figure in oncology with a significant number of publications and contributions to the field.
Protara Therapeutics, Inc. (Nasdaq: TARA) will present at the H.C. Wainwright BioConnect Virtual Conference from January 10-13, 2022. The presentation will be available on January 10 at 7:00 am ET through the Company's website. Protara focuses on developing therapies for cancer and rare diseases, featuring its lead program TARA-002 for non-muscle invasive bladder cancer and lymphatic malformations. Additionally, IV Choline Chloride targets intestinal failure-associated liver disease. The presentation will be archived for 90 days on their website.
Protara Therapeutics (TARA) announced significant advancements in its TARA-002 program, achieving FDA clearance for its IND application targeting non-muscle invasive bladder cancer (NMIBC). The company plans to initiate a Phase 1 clinical trial by year-end 2021. As of September 30, 2021, Protara reported strong cash reserves of $138.4 million, despite increasing R&D and administrative expenses leading to a net loss of $10.8 million for the quarter. The company also aims to engage the FDA for a trial design in lymphatic malformations.
Protara Therapeutics (Nasdaq: TARA) announced the grant of inducement stock options for 44,000 shares to Mary Grendell, the new General Counsel. Each option has an exercise price of $6.81, equal to the closing price on October 25, 2021. The options will vest over four years, with 25% vesting after one year and the remainder monthly over 36 months, contingent on Ms. Grendell's continued employment. The awards were approved by the Compensation Committee following Nasdaq Listing Rule 5635(c)(4).
Protara Therapeutics (Nasdaq: TARA) has received FDA clearance for its Investigational New Drug (IND) application for TARA-002, a cell-based therapy targeting non-muscle invasive bladder cancer (NMIBC). The company plans to initiate a Phase 1 study by the end of 2021 to evaluate TARA-002's safety, tolerability, and preliminary anti-tumor activity. TARA-002 is derived from the same master cell bank as OK-432, which is already approved for oncologic use in Japan and Taiwan. There is a pressing need for new NMIBC treatments due to rising recurrence rates among patients.
Protara Therapeutics, Inc. (Nasdaq: TARA) will present at the Oppenheimer Fall Healthcare Life Sciences & MedTech Summit on September 22, 2021, at 12:25 PM ET. The presentation will be accessible through a webcast on the Company's website and archived for 90 days post-event. Protara focuses on developing transformative therapies for cancer and rare diseases, including its lead program TARA-002 for non-muscle invasive bladder cancer and IV Choline Chloride for intestinal failure-associated liver disease.
Protara Therapeutics (TARA) announced a study revealing that approximately 30% of patients dependent on parenteral nutrition (PN) experience cholestasis, a key pathology of intestinal failure-associated liver disease (IFALD). This highlights an unmet medical need for effective treatments. The company is developing IV Choline Chloride as a replacement therapy for choline deficiency in PN patients, with promising results from prior studies. Protara's ongoing research aims to further investigate IFALD and assess the prevalence of choline deficiency among affected patients.
Protara Therapeutics, Inc. (Nasdaq: TARA) announced its participation in the H.C. Wainwright 23rd Annual Global Investment Conference, occurring virtually from September 13-15, 2021. The company's prerecorded presentation will be available on September 13, 2021, at 7:00am ET, accessible via the Events and Presentations section on their website. Protara focuses on developing therapies for cancer and rare diseases, including TARA-002 for bladder cancer and lymphatic malformations, as well as IV Choline Chloride for intestinal failure-associated liver disease.
Protara Therapeutics, Inc. (TARA) reported significant progress in developing TARA-002 for non-muscle invasive bladder cancer (NMIBC) and lymphatic malformations (LMs). As of June 30, 2021, the company holds $145 million in cash and investments. They completed IND-enabling studies and are on track to submit an IND application by year-end, aiming to initiate a Phase 1 trial for NMIBC. However, R&D expenses rose to $5.9 million, contributing to a net loss of $12.8 million for Q2 2021, compared to a $7.1 million loss in Q2 2020.