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Synlogic Reports Third Quarter 2024 Financial Results

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Synlogic (NASDAQ: SYBX) has reported its Q3 2024 financial results. The company ended the quarter with $19.4 million in cash and cash equivalents. The company reported no revenue, compared to $0.4 million in Q3 2023. There was a $0.7 million benefit in R&D expenses, compared to $9.6 million expenses in Q3 2023, due to clinical trial closeouts and Synpheny-3 discontinuation. G&A expenses decreased to $1.2 million from $3.4 million year-over-year. The company reported a net loss of $0.1 million ($0.01 per share), improved from a $12.1 million loss ($2.57 per share) in Q3 2023. The company has retained Lucid Capital Markets to explore strategic alternatives.

Synlogic (NASDAQ: SYBX) ha riportato i risultati finanziari per il terzo trimestre del 2024. L'azienda ha concluso il trimestre con 19,4 milioni di dollari in cassa e equivalenti in cassa. Non sono stati riportati ricavi, rispetto ai 0,4 milioni di dollari nel terzo trimestre del 2023. C'è stato un beneficio di 0,7 milioni di dollari nelle spese per R&S, rispetto a 9,6 milioni di dollari di spese nel terzo trimestre del 2023, a causa della chiusura degli studi clinici e della sospensione di Synpheny-3. Le spese generali e amministrative sono diminuite a 1,2 milioni di dollari rispetto ai 3,4 milioni dell'anno precedente. L'azienda ha riportato una perdita netta di 0,1 milioni di dollari (0,01 dollari per azione), in miglioramento rispetto a una perdita di 12,1 milioni di dollari (2,57 dollari per azione) nel terzo trimestre del 2023. L'azienda ha incaricato Lucid Capital Markets di esplorare alternative strategiche.

Synlogic (NASDAQ: SYBX) ha informado sus resultados financieros del tercer trimestre de 2024. La compañía terminó el trimestre con 19.4 millones de dólares en efectivo y equivalentes de efectivo. No reportó ingresos, en comparación con 0.4 millones de dólares en el tercer trimestre de 2023. Hubo un beneficio de 0.7 millones de dólares en gastos de I+D, en comparación con gastos de 9.6 millones de dólares en el tercer trimestre de 2023, debido al cierre de ensayos clínicos y a la discontinuación de Synpheny-3. Los gastos generales y administrativos disminuyeron a 1.2 millones de dólares de 3.4 millones del año anterior. La compañía reportó una pérdida neta de 0.1 millones de dólares (0.01 dólares por acción), mejorando de una pérdida de 12.1 millones de dólares (2.57 dólares por acción) en el tercer trimestre de 2023. La compañía ha contratado a Lucid Capital Markets para explorar alternativas estratégicas.

신로직 (NASDAQ: SYBX)은 2024년 3분기 재무 결과를 보고했습니다. 회사는 1940만 달러의 현금 및 현금 등가물로 분기를 마쳤습니다. 2023년 3분기의 40만 달러와 비교하여 수익은 보고되지 않았습니다. 연구개발(R&D) 비용에서 70만 달러의 혜택이 있었으며, 이는 2023년 3분기의 960만 달러의 비용과 비교됩니다. 이는 임상시험 종료 및 Synpheny-3의 중단에 기인합니다. 관리 및 일반 비용은 전년 대비 120만 달러로 감소했습니다 (340만 달러에서). 회사는 10만 달러의 순손실을 보고했으며 (주당 0.01 달러), 2023년 3분기의 1210만 달러 손실 (주당 2.57 달러)에서 개선되었습니다. 회사는 전략적 대안을 모색하기 위해 Lucid Capital Markets를 고용했습니다.

Synlogic (NASDAQ: SYBX) a publié ses résultats financiers pour le troisième trimestre 2024. La société a terminé le trimestre avec 19,4 millions de dollars en liquidités et équivalents de liquidités. Aucun revenu n'a été signalé, comparé à 0,4 million de dollars au troisième trimestre 2023. Il y a eu un bénéfice de 0,7 million de dollars dans les dépenses de R&D, contre 9,6 millions de dollars de dépenses au troisième trimestre 2023, en raison de la clôture des essais cliniques et de l'arrêt de Synpheny-3. Les dépenses générales et administratives ont diminué à 1,2 million de dollars, contre 3,4 millions l'année précédente. L'entreprise a rapporté une perte nette de 0,1 million de dollars (0,01 dollar par action), améliorée par rapport à une perte de 12,1 millions de dollars (2,57 dollars par action) au troisième trimestre 2023. La société a retenu Lucid Capital Markets pour explorer des alternatives stratégiques.

Synlogic (NASDAQ: SYBX) hat die Finanzzahlen für das dritte Quartal 2024 veröffentlicht. Das Unternehmen schloss das Quartal mit 19,4 Millionen Dollar an Bargeld und liquiden Mitteln. Es wurden keine Einnahmen gemeldet, im Vergleich zu 0,4 Millionen Dollar im dritten Quartal 2023. Es gab einen Vorteil von 0,7 Millionen Dollar bei den F&E-Ausgaben, verglichen mit 9,6 Millionen Dollar Ausgaben im dritten Quartal 2023, hauptsächlich aufgrund der Schließung klinischer Studien und der Einstellung von Synpheny-3. Die allgemeinen und Verwaltungsausgaben sanken auf 1,2 Millionen Dollar von 3,4 Millionen im Vorjahresvergleich. Das Unternehmen meldete einen Nettoverlust von 0,1 Millionen Dollar (0,01 Dollar pro Aktie), eine Verbesserung gegenüber einem Verlust von 12,1 Millionen Dollar (2,57 Dollar pro Aktie) im dritten Quartal 2023. Das Unternehmen hat Lucid Capital Markets beauftragt, strategische Alternativen zu prüfen.

Positive
  • Significant reduction in net loss to $0.1 million from $12.1 million YoY
  • Decreased G&A expenses by 65% to $1.2 million
  • Benefit of $0.7 million in R&D expenses due to trial closeouts
Negative
  • No revenue generation in Q3 2024 compared to $0.4M in Q3 2023
  • Discontinued Synpheny-3 pivotal study leading to restructuring charges
  • Workforce reduction and restructuring costs of $0.3 million
  • Strategic review indicates potential financial/operational challenges

Insights

The Q3 2024 financial results reveal a concerning picture despite the superficially improved net loss. The company's $19.4 million cash position and zero revenue generation raise significant liquidity concerns. The reduced net loss of $0.1 million versus $12.1 million year-over-year primarily stems from cost-cutting measures and one-time benefits, not operational improvements. The $0.7 million R&D benefit from trial closeouts and the significant reduction in G&A expenses to $1.2 million from $3.4 million reflect the company's strategic pivot and workforce reduction following the discontinuation of their pivotal Synpheny-3 study. The engagement of Lucid Capital Markets for strategic alternatives exploration suggests the company is actively seeking an exit strategy, which could range from a merger to an acquisition, though there's no guarantee of a successful transaction.

WINCHESTER, Mass., Nov. 12, 2024 (GLOBE NEWSWIRE) -- Synlogic, Inc. (Nasdaq: SYBX), a biopharmaceutical company advancing novel therapeutics to transform the care of serious diseases, today reported financial results for the third quarter 2024 and provided a corporate update.

As previously announced, the Company retained Lucid Capital Markets, LLC to act as its financial advisor to explore and evaluate strategic options for maximizing shareholder value. Potential strategic alternatives that may be explored or evaluated as part of this process include the potential for an acquisition, merger, business combination or other strategic transaction involving the Company. The Synlogic Board of Directors has not set a timetable for the conclusion of this review, nor has it made any decisions related to any further actions or potential strategic options at this time. There can be no assurance, however, that this process will result in any such transaction.

Third Quarter 2024 Financial Results

As of September 30, 2024 Synlogic had cash and cash equivalents of $19.4 million.

There was no revenue for the three months ended September 30, 2024, compared to $0.4 million for the corresponding period in 2023. Revenue for the three months ended September 30, 2023 was associated with the prior research collaboration with Roche.

There was a benefit of $0.7 million related to research and development expenses for the three months ended September 30, 2024, compared to expenses of $9.6 million for the corresponding period in 2023. During the three months ended September 30, 2024, Synlogic received a refund related to the closeout of one of its clinical trials and estimates of manufacturing expenses that Synlogic incurred were revised due to the decision to discontinue Synpheny-3, resulting in a benefit upon reversal of the accrual.

General and administrative expenses for the three months ended September 30, 2024 were $1.2 million compared to $3.4 million for the corresponding period in 2023.

There were restructuring charges of $0.3 million for the three months ended September 30, 2024. The restructuring and other charges were a result of the Company’s decision in February 2024 to discontinue Synpheny-3, its pivotal study of labafenogene marselecobac (SYNB1934) in phenylketonuria (PKU) and evaluate strategic options for the Company. The restructuring charges were primarily related to severance expense as a result of the reduction in workforce.

For the three months ended September 30, 2024, Synlogic reported a consolidated net loss of $(0.1) million, or ($0.01) per share, compared to a consolidated net loss of $(12.1) million, or $(2.57) per share, for the corresponding period in 2023.

About Synlogic

Synlogic is a biopharmaceutical company advancing novel therapeutics to transform the care of serious diseases in need of new treatment options. Synlogic designs, develops and manufactures these drug candidates, which are produced by applying precision genetic engineering to well-characterized probiotics.

Forward Looking Statements

This press release contains "forward-looking statements" that involve substantial risks and uncertainties for purposes of the safe harbor provided by the Private Securities Litigation Reform Act of 1995. All statements, other than statements of historical facts, included in this press release regarding strategy, future operations, clinical development plans, future financial position, future revenue, projected expenses, prospects, plans and objectives of management are forward-looking statements. In addition, when or if used in this press release, the words "may," "could," "should," "anticipate," "believe," "look forward," "estimate," "expect," “focused on,” "intend," "on track," "plan," "predict" and similar expressions and their variants, as they relate to Synlogic, may identify forward-looking statements.  Actual results could differ materially from those contained in any forward-looking statements as a result of various factors, including: the Company may not execute on its planned exploration and evaluation of strategic alternatives; and the availability of suitable third parties with which to conduct contemplated strategic transactions; as well as those risks identified under the heading "Risk Factors" in Synlogic's filings with the U.S. Securities and Exchange Commission. The forward-looking statements contained in this press release reflect Synlogic's current views with respect to future events. Synlogic anticipates that subsequent events and developments will cause its views to change. However, while Synlogic may elect to update these forward-looking statements in the future, Synlogic specifically disclaims any obligation to do so. These forward-looking statements should not be relied upon as representing Synlogic's view as of any date subsequent to the date hereof.

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Contact: info@synlogictx.com

         
  
Synlogic, Inc.
Condensed Consolidated Statements of Operations
(unaudited)
         
(in thousands, except share and per share data)For the Three Months Ended
September 30
 For the Nine Months Ended
September 30
   2024   2023   2024   2023 
         
Revenue$  $393  $8  $602 
         
Operating expenses       
 Research and development (713)  9,616   9,164   33,831 
 General and administrative 1,165   3,400   5,228   11,291 
 Restructuring and other charges 296      24,790    
Total operating expenses 748   13,016   39,182   45,122 
Loss from operations (748)  (12,623)  (39,174)  (44,520)
Total other income, net 631   548   16,534   1,784 
Loss before income taxes (117)  (12,075)  (22,640)  (42,736)
Income tax expense    (3)  (5)  (12)
Net loss$(117) $(12,078) $(22,645) $(42,748)
         
Net loss per share - basic and diluted$(0.01) $(2.57) $(1.86) $(9.17)
Weighted-average common shares used in computing net loss per share - basic and diluted 12,223,922   4,699,847   12,186,830   4,662,444 


 
Synlogic, Inc.
Condensed Consolidated Balance Sheets
(unaudited)
 
(in thousands, except share data)   
  September 30, 2024 December 31, 2023
Assets   
 Cash, cash equivalents & marketable securities$19,389  $47,746 
 Property and equipment, net    5,603 
 Other assets 1,366   22,201 
Total assets$20,755  $75,550 
     
Liabilities and stockholders' equity   
 Current liabilities$7,647  $30,288 
 Long-term liabilities    12,491 
 Total liabilities 7,647   42,779 
 Total stockholders' equity 13,108   32,771 
     
Total liabilities and stockholders' equity$20,755  $75,550 
     
Common stock and common stock equivalents   
 Common stock 11,696,109   9,186,157 
 Common stock warrants (pre-funded) 722,183   2,973,183 
Total common stock 12,418,292   12,159,340 


Certain prior period amounts have been revised to correct for an immaterial error impacting previously issued financial statements, which are more fully described in our Quarterly Report on Form 10-Q for the period ended September 30, 2024.


FAQ

What was Synlogic's (SYBX) net loss per share in Q3 2024?

Synlogic reported a net loss of $0.01 per share in Q3 2024, compared to a loss of $2.57 per share in Q3 2023.

How much cash does Synlogic (SYBX) have as of September 30, 2024?

Synlogic had cash and cash equivalents of $19.4 million as of September 30, 2024.

Why did Synlogic (SYBX) report an R&D benefit in Q3 2024?

Synlogic reported an R&D benefit of $0.7 million due to clinical trial closeout refunds and revised manufacturing expense estimates following the discontinuation of Synpheny-3.

What strategic alternatives is Synlogic (SYBX) exploring?

Synlogic is exploring potential strategic alternatives including an acquisition, merger, business combination, or other strategic transaction involving the Company.

Synlogic, Inc.

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Biotechnology
Pharmaceutical Preparations
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United States of America
WINCHESTER